Head and Neck Neoplasms: all 2,403 studies

Page 7 of 25. Open to participants first (559), then studies with results posted, then the rest; newest registration first within each.

• Phase 1/2a Study of SQ3370 in Patients With Advanced Solid TumorsTerminatedNCT04106492Phase 1/2Results posted
• CLR 131 Combined With Radiation for Head and Neck CancerCompletedNCT04105543Phase 1Results posted
• An Experimental Study to Compare Treatment Response and Toxicities of Concurrent Chemoradiation With Weekly Cisplatin and Three Weekly Cisplatin in Locally Advanced Head and Neck Cancer.CompletedNCT03998696Phase 2Results posted
• Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck CancerCompletedNCT03993353Phase 2Results posted
• Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid TumorsTerminatedNCT03991741Phase 1Results posted
• Impact of Therapeutic Patient Education on the Toxicity of Immune Checkpoint Inhibitors in OncologyCompletedNCT03948724Not applicableResults posted
• Abemaciclib and Pembrolizumab in Metastatic or Recurrent Head and Neck CancerTerminatedNCT03938337Phase 2Results posted
• Efficacy and Safety Trial of ADU-S100 and Pembrolizumab in Head and Neck CancerTerminatedNCT03937141Phase 2Results posted
• A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) TumorsActive, not recruitingNCT03899792Phase 1/2Results posted
• Induction TPN Followed by Nivolumab With Radiation in Locoregionally Advanced Laryngeal and Hypopharyngeal CancerCompletedNCT03894891Phase 2Results posted
• Paclitaxel vs Paclitaxel + Cetuximab in Recurrent - Metastatic Head & Neck Carcinoma After Failure of a 1º ChemotherapyTerminatedNCT03887442Phase 2Results posted
• Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced MalignanciesTerminatedNCT03881488Phase 1Results posted
• Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHNCompletedNCT03878979Phase 2Results posted
• CONNECTing Head and Neck Caregivers to Supportive Care ResourcesCompletedNCT03875885Not applicableResults posted
• Commensal Oral Microbiota in Head and Neck CancerTerminatedNCT03843554Not applicableResults posted
• Investigation of Two Swallowing Therapy Models During Radiation Therapy for Head and Neck CancerCompletedNCT03832686Not applicableResults posted
• Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) 2.0CompletedNCT03831100Not applicableResults posted
• A Phase I/II Clinical Trial of PepCan in Head and Neck Cancer PatientsCompletedNCT03821272Phase 1/2Results posted
• Single-arm Phase II Study of NDURE for Patients With HNCCompletedNCT03821064Not applicableResults posted
• IPI-549 in Patients With Locally Advanced HPV+ and HPV- Head and Neck Squamous Cell CarcinomaCompletedNCT03795610Phase 2Results posted
• This Study Tests How BI 754111 is Distributed in Patients With Advanced Non-small Cell Lung Cancer or Patients With Head and Neck Cancer Who Are Treated With BI 754091TerminatedNCT03780725Phase 1Results posted
• Cetuximab in Head and Neck Cancer PatientsCompletedNCT03769311Phase 2Results posted
• Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)Active, not recruitingNCT03765918Phase 3Results posted
• Flexible Intubation Scope With or Without Video Laryngoscope in Supporting Endotracheal Tube Placement in Patients With Head and Neck Cancer Before SurgeryCompletedNCT03757091Not applicableResults posted
• Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck CancerCompletedNCT03754933Phase 1/2Results posted
• Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck CancerCompletedNCT03733210Phase 1Results posted
• Porfimer Sodium Interstitial Photodynamic Therapy With or Without Standard of Care Chemotherapy in Treating Patients With Locally Advanced or Recurrent Head and Neck CancerTerminatedNCT03727061Phase 1Results posted
• Durvalumab (MEDI4736) With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaCompletedNCT03691714Phase 2Results posted
• ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer PatientsCompletedNCT03689712Phase 3Results posted
• Perioperative Analgesia Using Gabapentin in Head and Neck Cancer SurgeryTerminatedNCT03682367Phase 3Results posted
• Effect of Guided Imagery for Radiotherapy-Related Distress in Patients With Head and Neck CancerCompletedNCT03662698Not applicableResults posted
• Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCCTerminatedNCT03646461Phase 2Results posted
• A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer PatientsCompletedNCT03602911Phase 2Results posted
• Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001)TerminatedNCT03515824Phase 1Results posted
• Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior ImmunotherapyTerminatedNCT03463161Phase 2Results posted
• Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell CarcinomaCompletedNCT03422536Phase 2Results posted
• Brain Stimulation For Cancer SmokersCompletedNCT03419741Not applicableResults posted
• Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck CancerCompletedNCT03405142Phase 2Results posted
• Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck CancerCompletedNCT03377270Not applicableResults posted
• Bridge: Proactive Psychiatry Consultation and Case Management for Patients With CancerCompletedNCT03360695Not applicableResults posted
• Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)CompletedNCT03358472Phase 3Results posted
• Adjuvant Nivolumab After Salvage Resection in Head and Neck Cancer Patients Previously Treated With Definitive TherapyCompletedNCT03355560Phase 2Results posted
• Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free FlapsCompletedNCT03349034Phase 2Results posted
• Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former SmokersActive, not recruitingNCT03347838Phase 2Results posted
• A Pilot Study to Evaluate the Feasibility and Potential Effectiveness of the Flexitouch System Head and Neck TreatmentCompletedNCT03332160Not applicableResults posted
• Safety and Efficacy of MEDI0457 and Durvalumab in Participants With Human Papilloma Virus (HPV) Associated Recurrent/Metastatic Head and Neck CancerCompletedNCT03162224Phase 1/2Results posted
• A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)Active, not recruitingNCT03157128Phase 1/2Results posted
• Ruxolitinib in Operable Head and Neck CancerTerminatedNCT03153982Phase 2Results posted
• MAGE-A4ᶜ¹º³²T for Multi-TumorActive, not recruitingNCT03132922Phase 1Results posted
• Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck CancerCompletedNCT03109873Early Phase 1Results posted
• Kanglaite Reduce the Toxicity of Radiotherapy of Head and Neck Cancer Phase II StudyCompletedNCT03101514Phase 2Results posted
• A Study of AK-01 (LY3295668) in Solid TumorsCompletedNCT03092934Phase 1/2Results posted
• Targeting PD-1 Therapy Resistance With Focused High or High and Low Dose Radiation in SCCHNActive, not recruitingNCT03085719Phase 2Results posted
• Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell CarcinomaCompletedNCT03082534Phase 2Results posted
• P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCCCompletedNCT03077243Phase 2Results posted
• Using a Head and Neck Maskless Immobilization Device For Patients With Intracranial TumorsCompletedNCT03076255Not applicableResults posted
• Involved Field Elective Volume De-Intensification Radiation Therapy for Head and Neck CancerCompletedNCT03067610Phase 2Results posted
• The Addition of Pembrolizumab to Postoperative Radiotherapy in Cutaneous Squamous Cell Cancer of the Head and NeckCompletedNCT03057613Phase 2Results posted
• Radiotherapy Related Skin Toxicity: Mepitel® vs. Standard Care in Patients With Locally Advanced Head-and-Neck CancerCompletedNCT03047174Not applicableResults posted
• Study of Pembrolizumab (MK-3475) or Placebo With Chemoradiation in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-412/KEYNOTE-412)CompletedNCT03040999Phase 3Results posted
• Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid TumorsCompletedNCT03037385Phase 1/2Results posted
• Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck CancerCompletedNCT03032250Not applicableResults posted
• Self-Care for Head and Neck Cancer Survivors With Lymphedema and FibrosisCompletedNCT03030859Not applicableResults posted
• To Evaluate the Efficacy and Safety of SCB01A in Subjects With r/m Squamous Cell Head and Neck CancerTerminatedNCT03020823Phase 2Results posted
• Oral Decitabine (ASTX727) and Durvalumab in Recurrent and/or Metastatic Head and Neck Cancer PatientsCompletedNCT03019003Phase 1Results posted
• A Stepped Care Intervention to Reduce Disparities in Mental Health Services Among Cancer Patients and CaregiversCompletedNCT03016403Not applicableResults posted
• Cisplatin + Radiation in SCCHN and Correlation With Oxidative Stress MarkersActive, not recruitingNCT02994069Phase 2Results posted
• A Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck CancerCompletedNCT02990468Phase 1/2Results posted
• The Use of Integra in Coverage of Radial Forearm Free Flap Donor Site DefectTerminatedNCT02980601Not applicableResults posted
• Engagement of Patients With Advanced CancerCompletedNCT02966509Not applicableResults posted
• Response to Intermittent Pneumatic Compression Therapy in Head and Neck Cancer-Related LymphedemaCompletedNCT02946021Phase 1/2Results posted
• Window Study of Nivolumab With or Without Ipilimumab in Squamous Cell Carcinoma of the Oral CavityActive, not recruitingNCT02919683Phase 2Results posted
• Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid TumorsCompletedNCT02903914Phase 1Results posted
• Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal CancerCompletedNCT02865135Phase 1/2Results posted
• A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay StudyCompletedNCT02841748Phase 2Results posted
• Development and Evaluation of Rehabilitation Consult for Survivors of Head and Neck CancerCompletedNCT02836769Not applicableResults posted
• Study to Compare the Effect of Two Different Types of Humidifier on the Endotracheal Tube PatencyCompletedNCT02780765Not applicableResults posted
• Pembrolizumab in Combination With Cisplatin and Intensity Modulated Radiotherapy (IMRT) in Head and Neck CancerCompletedNCT02777385Phase 2Results posted
• Expansion Trial for Axitinib In Head And Neck CancerCompletedNCT02762513Phase 2Results posted
• DMH-Based Plan Evaluation and Inverse Optimization in RadiotherapyCompletedNCT02663817Not applicableResults posted
• Impact of Symbiotic Administration on Intestinal Function of Head and Neck Patients Surgically TreatedCompletedNCT02654652Not applicableResults posted
• Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related CancersCompletedNCT02648178Not applicableResults posted
• Phase II Trial of Adjuvant Cisplatin and Radiation With Pembrolizumab in Resected Head and Neck Squamous Cell CarcinomaActive, not recruitingNCT02641093Phase 2Results posted
• Patritumab With Cetuximab and a Platinum Agent for Squamous Cell Carcinoma (Cancer) of the Head and Neck (SCCHN )TerminatedNCT02633800Phase 2Results posted
• Pembrolizumab + Radiation for Locally Adv SCC of the Head and Neck (SCCHN) Not Eligible CisplatinCompletedNCT02609503Phase 2Results posted
• LigaSure Small Jaw® Versus Conventional Neck Dissection in Head and Neck Cancer PatientsCompletedNCT02597582Phase 4Results posted
• Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck CancerCompletedNCT02589938Not applicableResults posted
• Pembrolizumab in Combination With CRT for LA-SCCHNCompletedNCT02586207Phase 1Results posted
• Nab-Paclitaxel and Cisplatin or Nab-paclitaxel as Induction Therapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck (HNSCC)CompletedNCT02573493Phase 2Results posted
• A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid TumorsCompletedNCT02573259Phase 1Results posted
• Feasibility Study of the Head and Neck Survivorship Tool: Assessment and Recommendations (HN-STAR)CompletedNCT02571673Results posted
• Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) in Recurrent/Metastatic Head and Neck CancerCompletedNCT02551159Phase 3Results posted
• Image Guided Adaptive Radiotherapy in the Head-and-neck RegionCompletedNCT02545322Not applicableResults posted
• Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by SurgeryCompletedNCT02538510Phase 1/2Results posted
• A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT02521870Phase 1/2Results posted
• Surgery With or Without Adjuvant Stereotactic Body RadiotherapyCompletedNCT02516969Not applicableResults posted
• Study of SCB01A in Patient With Head and Neck CancerTerminatedNCT02488629Phase 2Results posted
• Gabapentin Compared to Standard of Care in Preventing Mucositis in Patients With Stage III-IV Head and Neck Cancer Undergoing Primary or Adjuvant Chemoradiation TherapyCompletedNCT02480114Phase 3Results posted
• Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerCompletedNCT02475213Phase 1Results posted
• A Web-Based Multimedia Intervention for Head and Neck Cancer PatientsCompletedNCT02442336Not applicableResults posted

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