Head and Neck Neoplasms: all 2,403 studies

Page 5 of 25. Open to participants first (559), then studies with results posted, then the rest; newest registration first within each.

• Home-based Respiratory Muscle Training for Minimizing Side Effects in Patients Undergoing Treatment for CancerRecruitingNCT05787834Not applicable
• IMM2520, a PD-L1 and CD47 Bispecific Antibody in Patients With Advanced Solid TumorsRecruitingNCT05780307Phase 1
• Postoperative Management for HNSCC Based on Pathological Response of Induction Chemotherapy and ImmunotherapyRecruitingNCT05777824Phase 2
• First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid TumorsRecruitingNCT05768139Phase 1/2
• Radiotherapy Combined With PD-1 Inhibitor and GM-CSF for Advanced Recurrent Metastatic Head and Neck TumorsRecruitingNCT05760196Phase 2
• Tislelizumab Combined APF Chemotherapy in the Treatment of Locally Advanced Head and Neck TumorsRecruitingNCT05758389Phase 2
• Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site SequelaeRecruitingNCT05757817Not applicable
• PREoPerAtive pREhabilitation in Patients With Head and Neck Cancer or Liver Cancer (PREPARE)RecruitingNCT05745558Not applicable
• The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery.RecruitingNCT05738603Not applicable
• Evaluation of the Efficacy and Safety of Local Cryotherapy Treatment of Recurrent Head and Neck Cancer in Irradiated Areas: a Pilot StudyRecruitingNCT05738187Not applicable
• Simultaneous Integrated Boost in Carbon Ion Radiotherapy for Head and Neck Adenoid Cystic CarcinomaRecruitingNCT05733910Not applicable
• Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCCRecruitingNCT05726370Phase 2
• A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid TumorsRecruitingNCT05706129Phase 1/2
• Preclinical Research for Personalized TCR-T Therapy for Head and Neck CancerRecruitingNCT05697926
• Multiparametric Imaging-based Intraoperative Navigation for Guidance of Surgical Resection and Postoperative Radiotherapy in Patients With Head-and-neck TumorsRecruitingNCT05671458Not applicable
• Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric PatientsRecruitingNCT05658731Not applicable
• Evaluation of Vascular Toxicity of Immune Checkpoint Inhibitors in Patients Head and Neck or Lung CancerRecruitingNCT05655663Not applicable
• Exploratory Study of Early Biomarkers Allowing Dynamic Assessment of Response to Treatment in Cancers of the Head and NeckRecruitingNCT05644457
• Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.RecruitingNCT05635929Not applicable
• Innovative Patient-partner-guided Virtual Group Speech Pathology Intervention Model in Head and Neck CancerRecruitingNCT05621889Phase 1/2
• Radiotherapy With Tislelizumab in Patients With Recurrent Head & Neck CancerRecruitingNCT05595590Phase 2
• A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid TumorsRecruitingNCT05592626Phase 1/2
• Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal CancersNot yet recruitingNCT05582590Phase 1
• A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)RecruitingNCT05576974Phase 2
• Drug Screening Using Novel IMD in Salivary and Head and Neck CancersRecruitingNCT05553782Early Phase 1
• Pivotal Study of Proton Radiotherapy Treatments Using Fixed Beam Chair-Based Delivery SystemRecruitingNCT05549414Not applicable
• A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck CancerRecruitingNCT05544136Phase 2
• Benefit of Paramedical Care in Accompanying Caregivers of Patients That Had Surgery for an Head and Neck Invasive CancerRecruitingNCT05542706Not applicable
• Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck CancerRecruitingNCT05526924Phase 1
• Expanded Access [11C] Methionine PET ImagingAvailableNCT05511714
• Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck CancerRecruitingNCT05505188Not applicable
• Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid TumorsRecruitingNCT05483400Phase 2
• The Head and Neck Registry of the European Reference Network on Rare Adult Solid CancersRecruitingNCT05483374
• Lung Ultrasound Score After ENT Cancer SurgeryRecruitingNCT05482841
• Sodium Selenite Supplementation in Patients With Head and Neck CancerRecruitingNCT05451576Not applicable
• Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCTRecruitingNCT05442957Not applicable
• Preventive Physical Activity Intervention in Head and Neck CancerRecruitingNCT05432297Not applicable
• 3D-PCT Combined With CT-guided Radioactive I-125 Seed Implantation in the Treatment of Head and Neck TumorsRecruitingNCT05421507
• A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck CancerRecruitingNCT05420948Phase 2
• Radiation Field, Dose and Fractionation Related to Mandibular ComplicationsRecruitingNCT05412849
• Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy SystemRecruitingNCT05406167
• Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)RecruitingNCT05403177
• InGReS: Intra-treatment Image Guided Adaptive Radiotherapy Dose-escalation StudyRecruitingNCT05393297Not applicable
• Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx CancerRecruitingNCT05388773Phase 2
• Individualized Follow-Up for Head and Neck CancerRecruitingNCT05386225
• Newer Therapeutic Targets in Head and Neck CancersRecruitingNCT05382585
• Immune Biomarker Study for Head and Neck CancerRecruitingNCT05375266
• PATH Trial: Personalized Approaches in the Treatment of Head and Neck CancerNot yet recruitingNCT05373251Not applicable
• cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseRecruitingNCT05366881
• ATATcH Alternating Treatment Plans for Advanced CancerRecruitingNCT05358548Phase 2
• FMISO-based Adaptive Radiotherapy for Head and Neck CancerRecruitingNCT05348486Not applicable
• Evaluation the Effects of Herbal Gargle for Chemoradiotherapy-induced Oral Mucositis of Head & Neck Cancer, a Pilot Study.Not yet recruitingNCT05341206Phase 2
• Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.RecruitingNCT05333523Phase 3
• Identification of Predictive Factors for the Response to Anti-Programmed Cell Death Protein 1 (PD1) Immunotherapy in Head and Neck Squamous Cell CarcinomaRecruitingNCT05328024
• The Clinical, Epidemiological and Treatment Characteristics of Head and Neck Cancer PatientsRecruitingNCT05319483
• Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated TumorsRecruitingNCT05313191Not applicable
• Penpulimab in Combination With Cetuximab as First-line Treatment in R/M SCCHNRecruitingNCT05260671Phase 2
• Measurement of Head and Neck Tumor Hypoxia With PET-MRIRecruitingNCT05246475Not applicable
• Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer?RecruitingNCT05217212
• A Study of Neurocognitive Tests and Questionnaires for People With Head and Neck Cancer Who Are Undergoing Radiation TherapyRecruitingNCT05207098
• A Single Arm, Prospective, Open Label, Multi Center, Phase Ib Study to Evaluate the Safety, Tolerability and Initial Efficacy of a Single Intra-tumoral Injection of IntraGel's Polymer-based Cisplatin-loaded Gel (TumoCure) in Subjects With Progressive or Radio-resistant Primary Head and Neck TumorRecruitingNCT05200650Phase 1
• A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid TumorRecruitingNCT05194982Phase 1
• The SWOAR Trial Sparing of Swallowing and Aspiration Related Organs at Risk & Submandibular Gland With Intensity Modulated Radiotherapy Versus Standard IMRT in Head and Neck Squamous Cell CarcinomasRecruitingNCT05187091Phase 3
• LEARN: Learning Environment for Artificial Intelligence in Radiotherapy New TechnologyRecruitingNCT05184790
• GH21 Capsules for Advanced Solid Tumors: A Study on Safety and Early ResultsRecruitingNCT05183243Phase 1
• Individualized Response-adaptive Radiation Dose Prescription in HNC Based on MRIRecruitingNCT05160714Phase 1
• Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck CancerRecruitingNCT05156060Phase 1/2
• Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER StudyRecruitingNCT05106608Not applicable
• Head and Neck Early Relapse Detection Study (HERD)RecruitingNCT05097625
• Circulating Immunes Cells, Cytokines and Brain RadiotherapyRecruitingNCT05082961Not applicable
• MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid TumorsRecruitingNCT05076760Phase 1
• AB122 Platform StudyRecruitingNCT04999761Phase 1
• Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICIRecruitingNCT04954599Phase 1/2
• Study of MCLA-129, a Human Bispecific EGFR and cMet Antibody, in Patients With Advanced NSCLC and Other Solid TumorsRecruitingNCT04930432Phase 1/2
• Improving Care for Rural Patients With Solid TumorsRecruitingNCT04916990Not applicable
• Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck CancerRecruitingNCT04915183Phase 2
• Meridian Energy Changes of Head and Neck Cancer Patients After Chemotherapy or RadiotherapyRecruitingNCT04872517Not applicable
• The Evaluation of Manual Therapy for the Prevention of Radiation-Induced Fibrosis in Patients With Head and Neck CancerRecruitingNCT04850170Not applicable
• Microbiota and Symptom Distress in Head and Neck Cancer Patients Receiving RadiotherapyNot yet recruitingNCT04843644Not applicable
• Study Evaluating Near-infrared Imaging Coupled With Indocyanine Green for Intraoperative Control of Resection Margins in ENT SurgeryRecruitingNCT04842162Phase 2
• MR-Linac for Head and Neck SBRTNot yet recruitingNCT04809792Not applicable
• Study of Non-invasive Acupuncture-like Transcutaneous Electrical Nerve Stimulation (Altens) to Help Alleviate Xerostomia After Radiation Therapy for Cancers of the Head and NeckRecruitingNCT04805528Not applicable
• Early Feeding After Oral Cavity ReconstructionRecruitingNCT04787939Not applicable
• Interest of Bilateral Basic Tongue Mucosectomy Assisted by Robot or Laser in Combination with Tonsillectomy in the Assessment of Prevalent Cervical LymphadenopathyRecruitingNCT04767048Phase 2
• MAGE-C2 TCR T Cell Trial to Treat Melanoma and Head and Neck CancerRecruitingNCT04729543Phase 1/2
• A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck CancerRecruitingNCT04722523Phase 1
• Neurosensorial Disorder and Pain in Oral Cavity and Oropharynx Cancer Traited Patients (OCAPA)RecruitingNCT04673981Not applicable
• Exploratory Study of Clonal Evolution in Cancer for Patients Undergoing Transoral Robotic Surgery for Radiation Exposed Residual/reCurrent Tumours of the Upper Aerodigestive TractRecruitingNCT04671940
• Study of a 1-Millimeter Resolution Clinical Positron Emission Tomography (PET) System in Head and Neck Cancer ImagingNot yet recruitingNCT04662554Not applicable
• A Motion Exergaming Approach for Symptom Management: HNCRecruitingNCT04632654Not applicable
• The EMINENCE Study - PET/MR Imaging of Head Neck CancerRecruitingNCT04612075
• Immunonutrition and Tolerance to Chemoradiotherapy in Patients With Head-neck CancerRecruitingNCT04611113Not applicable
• DAHANCA 35: Proton Versus Photon Therapy for Head-neck CancerRecruitingNCT04607694Not applicable
• Submandibular Gland Stem Cell TransplantationRecruitingNCT04593589Phase 1
• The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)RecruitingNCT04585750Phase 1/2
• Specific Methylation Profiles in HNSCCRecruitingNCT04567056
• Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesAvailableNCT04566393
• Jump: MR Simulation For Radiation Therapy Master ProtocolRecruitingNCT04545957Not applicable
• Phase II Panitumumab-IRDye800 in Head & Neck CancerRecruitingNCT04511078Phase 2
• A Multicenter Cancer Biospecimen Collection StudyRecruitingNCT04510129

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