An interventional study of Radiotherapy on the MR-Linac and Imaging on the MR Linac in Rectal Cancer, Head and Neck Cancer and Liver Cancer, sponsored by University Hospital Tuebingen. Recruiting at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-11-21.
Sponsored by University Hospital Tuebingen · Not applicable, Interventional, and Treatment
This study investigates the feasibility of imaging and treatment on a novel 1.5 T MR-Linac radiotherapy hybrid device.
Novel hybrid devices combine magnetic resonance imaging (MRI) and a linear accelerator in a single device. The superior soft tissue contrast compared with cone-beam computed tomography based treatment and the possibility for daily plan adaptation promise a higher precision of treatment, better target volume coverage and normal tissue sparing. In a first step the present study will test the feasibility of imaging and treatment on the 1.5 T MR-Linac.
1,804 studies on the registry are indexed under Rectal Neoplasms; 520 are open to participants now.
This study's planned enrollment of 472 is above the median of 66 across 1,330 interventional studies indexed under Rectal Neoplasms.
Browse Rectal Neoplasms studies →University Hospital Tuebingen is the lead sponsor of 490 studies on the registry; 108 are open to participants now.
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Exclusion Criteria:
In this arm patients with rectal and anal cancer are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients with prostate cancer are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients with head and neck cancers are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients with esophageal cancer are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients with breast cancer are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients with tumors of the central nervous system are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients with palliative treatments are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients with other tumors are recruited.
Radiation: Radiotherapy on the MR-Linac
In this arm patients receive only imaging on the MR-Linac
Diagnostic Test: Imaging on the MR Linac
Radiotherapy is performed on the 1.5 T MR Linac
Only imaging performed on the MR Linac
Feasibility of online MR guided Radiotherapy
Treatment of a patient is considered feasible when 85% of treatments were completed as planned in this patient
Time frame: During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy)
Time analysis
Time required for online MR guided radiotherapy
Time frame: During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy)
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