Hyperthyroidism clinical trials
The registry lists 112 studies for Hyperthyroidism across more than 10 countries. 27 are recruiting or about to start. 43 of them are mainly about Hyperthyroidism (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 3 narrower conditions too, such as Graves Ophthalmopathy: 408 studies, 119 open.
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Who runs them
University Hospital, Basel, Switzerland (3) · Biohaven Therapeutics Ltd. (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Mashhad University of Medical Sciences (2) · Hospital de Clinicas de Porto Alegre (2) · Centre Hospitalier Princesse Grace (2) · Sun Yat-sen University (2) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2)
What is being tested here
Drugs under test in Hyperthyroidism studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026A Clinical Study of Hyperthyroidism in Children · Shengjing Hospital
- Dec 2026Evaluation of Levothyroxine Replacement Therapy After Total Thyroidectomy Using a Smart Wristband · Yeditepe University Hospital
- Apr 2027Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter Registry · Sarasota Memorial Health Care System
- Jun 2027AI-Based Wearable Monitoring (Glandy HYPER) for Antithyroid Drug Dose Adjustment in Graves' Disease · THYROSCOPE INC.
- Jul 2027Iodine Supplementation in Graves' Hyperthyroidism · Shandong Provincial Hospital
- Sep 2027Study of BHV-1300 in Graves' Disease · Biohaven Therapeutics Ltd.
Who these studies take
Of the 17 Hyperthyroidism studies recruiting now, 8 (47%) set no upper age limit and 7 (41%) stop at 75 or younger. 4 (24%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (24%) | 4 (24%) |
| 18 | 15 (88%) | 15 (88%) |
| 30 | 16 (94%) | 16 (94%) |
| 40 | 16 (94%) | 16 (94%) |
| 50 | 16 (94%) | 16 (94%) |
| 65 | 16 (94%) | 16 (94%) |
| 75 | 13 (76%) | 13 (76%) |
| 85 | 9 (53%) | 9 (53%) |
Across all 112 studies, recruiting or not: 39% stop at 75 or younger and 25% at 65; 13% take children; 5% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hyperthyroidism studies take
Of 20 observational studies under Hyperthyroidism, half reached primary completion within 31 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 13 mo6–46 · 15 studies | — | — |
| Observational | 31 mo10–48 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered2
- An Open-Label Study to Determine if BHV-1300 is Safe in Adults With Graves' DiseaseOct 28, 2026NCT07901244
- Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye DiseaseOct 21, 2026NCT07885605
Studies
Recruiting first, then most recently updated. Showing 50 of 112. Browse all 112 → or search them.
- Natural History of Thyroid Function DisordersRecruitingNCT000011591 country
- Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' DiseaseRecruitingNCT07682896Phase 22 countries
- NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' DiseaseRecruitingNCT07305818Phase 12 countries
- An Open-Label Study to Determine if BHV-1300 is Safe in Adults With Graves' DiseaseNot yet recruitingNCT07901244Phase 2/3
- A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years OldRecruitingNCT07722546Phase 22 countries
- Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye DiseaseRecruitingNCT07885605Phase 11 country
- Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' DiseaseRecruitingNCT07661056Phase 33 countries
- AI-Based Wearable Monitoring (Glandy HYPER) for Antithyroid Drug Dose Adjustment in Graves' DiseaseNot yet recruitingNCT07857421Not applicable1 country
- Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter RegistryEnrolling by invitationNCT068684591 country
- Evaluation of Levothyroxine Replacement Therapy After Total Thyroidectomy Using a Smart WristbandRecruitingNCT07733375Not applicable1 country
- A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' DiseaseRecruitingNCT06727604Phase 210 countries
- Study of BHV-1300 in Graves' DiseaseRecruitingNCT06980649Phase 12 countries
- Evaluating an AI Tool for Detecting Thyrotoxic StatesRecruitingNCT070179071 country
- Efficacy of Thermal Ablation Combined With Antithyroid Drugs in the Treatment of Primary HyperthyroidismRecruitingNCT075578101 country
- Impact of Thyroid Hormones on Human Glucose and Energy MetabolismRecruitingNCT07410637Not applicable1 country
- A Brief Video Intervention to Improve Patient Outcomes Following Radioiodine TreatmentNot yet recruitingNCT07405320Not applicable
- Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular GoiterRecruitingNCT04856488Phase 31 country
- Hyperthyroidism as a Potential Predictive of Worse Outcome of Renal GraftRecruitingNCT067942031 country
- Evaluation of Different Diagnostic Therapeutic Strategies in Patients with Thyroid PathologyRecruitingNCT067797471 country
- Quest to Analyze One Thousand Humans MeditatingEnrolling by invitationNCT065833951 country
- Evaluation of Renal Function in Patients With HyperthyroidismNot yet recruitingNCT06591858
- A Clinical Study of Hyperthyroidism in ChildrenRecruitingNCT065709671 country
- Iodine Supplementation in Graves' HyperthyroidismNot yet recruitingNCT06540469Not applicable
- A Randomized Clinical Trial of Intravenous Methylprednisolone With 2 Protocols in Patients With Graves OrbitopathyNot yet recruitingNCT06510114Phase 4
- Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone StabilizationEnrolling by invitationNCT064528231 country
- Povidone Iodine Irrıgation at Hip-Knee ArthroplastyRecruitingNCT05599841Not applicable1 country
- Awareness of Osteoporosis in Patients With HyperthyroidismNot yet recruitingNCT05760417
- Tocilizumab in Active Moderate-severe Graves' OrbitopathyCompletedNCT04876534Phase 21 country
- Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' DiseaseActive, not recruitingNCT07369063Phase 21 country
- A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves' DiseaseCompletedNCT05907668Phase 21 country
- The Effect of SPU on Hormonal and Cardiometabolic FactorsCompletedNCT07688824Not applicable1 country
- Virtual Reality on Stress, Pain Levels in Patients With Hyperthyroidism Undergoing BiopsyCompletedNCT07066241Not applicable1 country
- Tocilizumab in Corticosteroid-Resistant Graves' Orbitopathy (Thyroid Eye Disease)CompletedNCT063675171 country
- Thyroid Uptake Quantification Validation on a Three-dimensional (3D) Cadmium-Zinc-Telluride (CZT) New Generation Gamma CameraCompletedNCT076104601 country
- A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye DiseaseActive, not recruitingNCT06088979Phase 211 countries
- Development of a Non-Invasive Prognostic Test for Graves OrbitopathyActive, not recruitingNCT07472062Not applicable1 country
- The Sequestration of Holistic Stress Management Techniques for AdultsWithdrawnNCT06098755Not applicable1 country
- Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid SurgeryCompletedNCT07274670Not applicable1 country
- Prospective, Observational Study on the Carotid Intima-media Thickness in Patients Undergoing Thyroid SurgeryWithdrawnNCT057745351 country
- Optimization With a Gamma Camera of the Individualized Patient Dosimetry in Radioiodine Therapy of Thyroid DiseasesCompletedNCT06371339Not applicable1 country
- Radiofrequency Ablation Versus I-131 for Solitary Autonomous Thyroid NodulesTerminatedNCT05142904Phase 31 country
- Assessment of THL and Potential Risk of Hypothyroidism in Healthcare Workers Exposed to Low-dose Ionizing RadiationActive, not recruitingNCT070485481 country
- Hyperthyroidism: Methimazole Plus L-carnitine and SeleniumCompletedNCT04946123Not applicable1 country
- Calcium+Calcitriol Versus PTH for the Prevention of Hypocalcemia in Thyroidectomy. Randomized Clinical TrialCompletedNCT05252884Not applicable1 country
- Expanded Access Protocol of Teprotumumab (HZN-001) for Patients With Active Thyroid Eye DiseaseApproved for marketingNCT040408941 country
- Pharmacist Role in Thyroid DisordersCompletedNCT06408909Not applicable1 country
- Clinical Study of Ultrasound-guided Radiofrequency Ablation in the Treatment of Refractory HyperthyroidismActive, not recruitingNCT06305871Not applicable1 country
- Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of HyperthyroidismCompletedNCT049321351 country
- The Role of Thyroid Status in Regulating Brown Adipose Tissue Activity, White Adipose Tissue Partitioning and Resting Energy ExpenditureCompletedNCT030645421 country
- Clinical Feasibility of Disease Managing Mobile App for HyperthyroidismStatus unknownNCT05828732Not applicable1 country