Glioblastoma: all 1,951 studies

Page 6 of 20. Open to participants first (457), then studies with results posted, then the rest; newest registration first within each.

• Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 MutationsActive, not recruitingNCT03581292Phase 2Results posted
• Mathematical Model-Adapted Radiation In GlioblastomaCompletedNCT03557372Not applicableResults posted
• Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their CaregiversCompletedNCT03538587Not applicableResults posted
• Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent GliomasCompletedNCT03532295Phase 2Results posted
• Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed GlioblastomaCompletedNCT03522298Phase 2Results posted
• Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint BlockadeCompletedNCT03493932Phase 1Results posted
• Testing Ramipril to Prevent Memory Loss in People With GlioblastomaCompletedNCT03475186Phase 2Results posted
• Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed GlioblastomaCompletedNCT03463265Phase 2Results posted
• Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in GBMActive, not recruitingNCT03452579Phase 2Results posted
• Trial of Combination Tumor Treating Fields (TTF; Optune), Nivolumab Plus/Minus Ipilimumab for Recurrent GlioblastomaTerminatedNCT03430791Phase 2Results posted
• Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed GlioblastomaCompletedNCT03426891Phase 1Results posted
• UNITE Study: Understanding New Interventions With GBM ThErapyTerminatedNCT03419403Phase 3Results posted
• Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)Active, not recruitingNCT03405792Phase 2Results posted
• Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only SubjectsTerminatedNCT03393000Phase 3Results posted
• Phase I Study of APX005M in Pediatric Central Nervous System TumorsCompletedNCT03389802Phase 1Results posted
• Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated GlioblastomaCompletedNCT03367715Phase 2Results posted
• Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma MultiformeTerminatedNCT03363659Phase 2Results posted
• Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With GlioblastomaTerminatedNCT03347617Phase 2Results posted
• A Phase III Trial of With Marizomib in Patients With Newly Diagnosed GlioblastomaCompletedNCT03345095Phase 3Results posted
• A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPGTerminatedNCT03330197Phase 1/2Results posted
• Study of AMG 596 in Patients With EGFRvIII Positive GlioblastomaTerminatedNCT03296696Phase 1Results posted
• Feasibility Study of Modified Atkins Ketogenic Diet in the Treatment of Newly Diagnosed Malignant GliomaCompletedNCT03278249Not applicableResults posted
• Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaTerminatedNCT03250299Phase 1Results posted
• Multi-kinase Inhibitor TG02 (TG02) in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma.CompletedNCT03224104Phase 1Results posted
• HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent GlioblastomaCompletedNCT03216499Phase 2Results posted
• Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 MutationsActive, not recruitingNCT03212274Phase 2Results posted
• Pembrolizumab and Standard Therapy in Treating Patients With GlioblastomaActive, not recruitingNCT03197506Phase 2Results posted
• Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT03174197Phase 1/2Results posted
• Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With CancerCompletedNCT03154190Not applicableResults posted
• A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent GlioblastomaCompletedNCT03150862Phase 1/2Results posted
• A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial TherapyCompletedNCT03149003Phase 3Results posted
• Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed GlioblastomaCompletedNCT03139916Phase 2Results posted
• Spectroscopic MRI-Guided Radiation Therapy Planning in GlioblastomaCompletedNCT03137888Phase 2Results posted
• HUMC 1612: Optune NovoTTF-200A SystemCompletedNCT03128047Phase 1Results posted
• BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent GlioblastomaTerminatedNCT03119064Phase 1/2Results posted
• Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant GliomaCompletedNCT03072134Phase 1Results posted
• Avelumab in Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT03047473Phase 2Results posted
• Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in ChildrenCompletedNCT03043391Phase 1Results posted
• Safety, Tolerability and Efficacy of Disulfiram and Copper Gluconate in Recurrent GlioblastomaCompletedNCT03034135Phase 2Results posted
• Protein Phosphatase 2A Inhibitor, in Recurrent GlioblastomaCompletedNCT03027388Phase 2Results posted
• Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic AstrocytomaTerminatedNCT03022578Phase 2Results posted
• NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing SurgeryCompletedNCT03020017Early Phase 1Results posted
• Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)TerminatedNCT03018288Phase 2Results posted
• Lerapolturev in Recurrent Malignant GliomaCompletedNCT02986178Phase 2Results posted
• A Study of Abemaciclib in Recurrent GlioblastomaActive, not recruitingNCT02981940Phase 2Results posted
• Cediranib Maleate and Olaparib Compared to Bevacizumab in Treating Patients With Recurrent GlioblastomaActive, not recruitingNCT02974621Phase 2Results posted
• Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant GlioblastomaCompletedNCT02968940Phase 2Results posted
• Engagement of Patients With Advanced CancerCompletedNCT02966509Not applicableResults posted
• Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and GlioblastomaTerminatedNCT02942264Phase 1/2Results posted
• Phase 1/2a Study of BAL101553 as 48-hour Infusions in Patients With Advanced Solid Tumors or Recurrent GlioblastomaCompletedNCT02895360Phase 1/2Results posted
• Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in ChildrenTerminatedNCT02885324Phase 2Results posted
• Peptide Targets for Glioblastoma Against Novel Cytomegalovirus AntigensTerminatedNCT02864368Phase 1Results posted
• Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive GlioblastomaCompletedNCT02858895Phase 2Results posted
• Study of Tesevatinib Monotherapy in Patients With Recurrent GlioblastomaCompletedNCT02844439Phase 2Results posted
• A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With GlioblastomaCompletedNCT02805179Phase 2Results posted
• Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant GliomaCompletedNCT02794883Phase 2Results posted
• Temozolomide Chronotherapy for High Grade GliomaCompletedNCT02781792Phase 2Results posted
• Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)TerminatedNCT02765165Phase 1/2Results posted
• Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent GlioblastomaTerminatedNCT02743078Phase 2Results posted
• Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed GlioblastomaCompletedNCT02715609Phase 1/2Results posted
• Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced MalignanciesTerminatedNCT02711137Phase 1/2Results posted
• Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid TumorsTerminatedNCT02709889Phase 1/2Results posted
• Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG TumorsCompletedNCT02684058Phase 2Results posted
• An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)CompletedNCT02667587Phase 3Results posted
• EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant GliomaTerminatedNCT02664363Phase 1Results posted
• TTFields and Pulsed Bevacizumab for Recurrent GlioblastomaTerminatedNCT02663271Phase 2Results posted
• Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With GlioblastomaCompletedNCT02661282Phase 1/2Results posted
• Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001CompletedNCT02655601Phase 1/2Results posted
• Phase 0 Analysis of Ixazomib (MLN9708) in Patients With GlioblastomaCompletedNCT02630030Early Phase 1Results posted
• An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)CompletedNCT02617589Phase 3Results posted
• A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)Active, not recruitingNCT02586857Phase 1/2Results posted
• A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) AmplificationCompletedNCT02573324Phase 3Results posted
• Phase 2 Study of Sym004 for Adult Patients With Recurrent GlioblastomaCompletedNCT02540161Phase 2Results posted
• Nivolumab With DC Vaccines for Recurrent Brain TumorsCompletedNCT02529072Phase 1Results posted
• Oral ONC201 in Adult Recurrent GlioblastomaTerminatedNCT02525692Phase 2Results posted
• Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade GliomaCompletedNCT02490800Phase 1/2Results posted
• Trial of Ponatinib in Patients With Bevacizumab-Refractory GlioblastomaCompletedNCT02478164Phase 2Results posted
• Ceritinib Rare Indications Study in ALK+ TumorsTerminatedNCT02465528Phase 2Results posted
• Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma MultiformeCompletedNCT02465268Phase 2Results posted
• SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed GlioblastomaActive, not recruitingNCT02455557Phase 2Results posted
• A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or ImmunotherapyCompletedNCT02431572Not applicableResults posted
• 89Zr-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients With Glioblastoma MultiformeCompletedNCT02410577Not applicableResults posted
• Methoxyamine and Temozolomide in Treating Patients With Recurrent GlioblastomaTerminatedNCT02395692Phase 2Results posted
• Dose Escalated MRSI Guided Radiation Therapy in GlioblastomaTerminatedNCT02394665Phase 2Results posted
• Improving Goals of Care Discussion in Advanced Cancer PatientsCompletedNCT02374255Not applicableResults posted
• Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain TumorsTerminatedNCT02372409Phase 2Results posted
• DC Migration Study for Newly-Diagnosed GBMCompletedNCT02366728Phase 2Results posted
• A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)TerminatedNCT02343549Phase 2Results posted
• Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade GliomasCompletedNCT02343406Phase 2Results posted
• TH-302 in Combination With Bevacizumab for GlioblastomaCompletedNCT02342379Phase 2Results posted
• Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent GlioblastomaTerminatedNCT02340156Phase 2Results posted
• Pembrolizumab in Treating Patients With Recurrent GlioblastomaActive, not recruitingNCT02337686Phase 2Results posted
• Pembrolizumab +/- Bevacizumab for Recurrent GBMCompletedNCT02337491Phase 2Results posted
• Phase 2 Study of Durvalumab (MEDI4736) in Patients With GlioblastomaCompletedNCT02336165Phase 2Results posted
• Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and BevacizumabCompletedNCT02330562Phase 1/2Results posted
• A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)CompletedNCT02327078Phase 1/2Results posted
• Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade GliomasCompletedNCT02323880Phase 1Results posted
• A Study of BBI608 in Combination With Temozolomide in Adult Patients With Recurrent or Progressed GlioblastomaCompletedNCT02315534Phase 1/2Results posted
• A Dose-finding Study of Birabresib (MK-8628) in Participants With Recurrent Glioblastoma Multiforme (MK-8628-002)TerminatedNCT02296476Phase 2Results posted
• Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System TumorsTerminatedNCT02255461Phase 1Results posted

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