Glioblastoma: all 1,951 studies

Page 5 of 20. Open to participants first (457), then studies with results posted, then the rest; newest registration first within each.

• The PROGRAM-study: Awake Mapping Versus Asleep Mapping Versus No Mapping for Glioblastoma ResectionsRecruitingNCT04708171
• LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)RecruitingNCT04699773Not applicable
• A Trial of RSC-1255 for Treatment of Patients With Advanced MalignanciesRecruitingNCT04678648Phase 1
• Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) GlioblastomasRecruitingNCT04623931Phase 2
• Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated GlioblastomaRecruitingNCT04590664Phase 1/2
• A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First ProgressionRecruitingNCT04573192Phase 1/2
• A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)RecruitingNCT04573140Phase 1
• Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesAvailableNCT04566393
• Sacituzumab Govitecan in Recurrent GlioblastomaRecruitingNCT04559230Phase 2
• Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant GliomaRecruitingNCT04547777Phase 1
• Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsRecruitingNCT04541082Phase 1
• Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma.Not yet recruitingNCT04536649Phase 3
• Acetyl-Amantadine as a Biomarker in Patients With GlioblastomaRecruitingNCT04530006Not applicable
• Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in GlioblastomaRecruitingNCT04523688Phase 2
• Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain TumorsRecruitingNCT04479696Not applicable
• Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed GlioblastomaRecruitingNCT04443010Phase 1/2
• NG101m Adjuvant Therapy in Glioblastoma PatientsNot yet recruitingNCT04373785Phase 1/2
• Improving Treatment of Glioblastoma: Distinguishing Progression From PseudoprogressionRecruitingNCT04359745
• Study of Recombinant Human Endostatin Combined with Temozolomide and Irinotecan in Recurrent GliomasRecruitingNCT04267978Phase 2
• Restrictive Use of Dexamethasone in GlioblastomaRecruitingNCT04266977Not applicable
• Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery)RecruitingNCT04223999Phase 2
• Serial MRI Scans During Radiation TherapyRecruitingNCT04188535Not applicable
• Implantable Microdevice In Primary Brain TumorsRecruitingNCT04135807Early Phase 1
• A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 AlterationsRecruitingNCT04094610Phase 1/2
• B7-H3 CAR-T for Recurrent or Refractory GlioblastomaRecruitingNCT04077866Phase 1/2
• Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System LesionsRecruitingNCT04047264Not applicable
• A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GlioblastomaRecruitingNCT03970447Phase 2/3
• Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan StudyEnrolling by invitationNCT03951142Phase 2
• Immune Modulatory DC Vaccine Against Brain TumorNot yet recruitingNCT03914768Phase 1
• HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 1
• MSC-DNX-2401 in Treating Patients With Recurrent High-Grade GliomaRecruitingNCT03896568Phase 1
• The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.RecruitingNCT03861299Not applicable
• Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer PatientsRecruitingNCT03787056Not applicable
• IA Carboplatin + Radiotherapy in Relapsing GBMRecruitingNCT03672721Phase 1/2
• Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17)RecruitingNCT03643549Phase 1/2
• HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBMRecruitingNCT03603405Phase 1/2
• HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBMRecruitingNCT03596086Phase 1/2
• PreOperative Brain Irradiation in GlioblastomaRecruitingNCT03582514Phase 1
• Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard TherapyRecruitingNCT03548571Phase 2/3
• SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryRecruitingNCT03452774
• Intracranial Injection of NK-92/5.28.z Cells in Combination With Intravenous Ezabenlimab in Patients With Recurrent HER2-positive GlioblastomaRecruitingNCT03383978Phase 1
• Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBMRecruitingNCT03213002Phase 1/2
• APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsRecruitingNCT03175224Phase 2
• Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of RadiochemotherapyRecruitingNCT03144167Not applicable
• Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBMRecruitingNCT03008148Phase 2/3
• Integrative Analysis of Human Glioblastoma MultiformeRecruitingNCT03005132
• INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)RecruitingNCT02977780Phase 2
• Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed GlioblastomaRecruitingNCT02861898Phase 1/2
• Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOARecruitingNCT02800486Phase 2
• Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed GlioblastomasRecruitingNCT02613988Not applicable
• Surgery for Recurrent GlioblastomaRecruitingNCT02394626Phase 2
• Super-Selective Intraarterial Intracranial Infusion of Bevacizumab (Avastin) for Glioblastoma MultiformeRecruitingNCT02285959Phase 1
• Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221AvailableNCT02146066
• Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)RecruitingNCT01906385Phase 1/2
• Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma MultiformNot yet recruitingNCT01777919Phase 2
• Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AARecruitingNCT01269853Phase 1/2
• Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma MultiformeRecruitingNCT00083512
• A Study to Investigate 14C-bemcentinib in Healthy Male SubjectsCompletedNCT06469138Phase 1Results posted
• A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma PatientsTerminatedNCT05753007Phase 2Results posted
• Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line ChemotherapyCompletedNCT05718466Phase 3Results posted
• Tofacitinib in Recurrent GBM PatientsCompletedNCT05326464Phase 3Results posted
• PARP Inhibition for Gliomas (PI-4G or π4g)TerminatedNCT05297864Phase 2Results posted
• ETAPA I: Peptide-based Tumor Associated Antigen Vaccine in GBMActive, not recruitingNCT05283109Phase 1Results posted
• Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 AlterationsTerminatedNCT05267106Phase 2Results posted
• Accurate DCE-MRI Measurement of Glioblastoma Using Point-of-care Portable Perfusion PhantomCompletedNCT05140902Not applicableResults posted
• A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in GlioblastomaActive, not recruitingNCT04900792Phase 1Results posted
• Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical TrialTerminatedNCT04825275Early Phase 1Results posted
• Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas SystemCompletedNCT04743310Phase 2Results posted
• Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent GlioblastomaActive, not recruitingNCT04729959Phase 2Results posted
• LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent GlioblastomaCompletedNCT04479241Phase 2Results posted
• Mycophenolate Mofetil Combined With Radiation Therapy in GlioblastomaActive, not recruitingNCT04477200Phase 1Results posted
• Infigratinib in Recurrent High-Grade Glioma PatientsTerminatedNCT04424966Early Phase 1Results posted
• A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent GlioblastomaTerminatedNCT04421378Phase 1/2Results posted
• VB-111 in Surgically Accessible Recurrent/Progressive GBMTerminatedNCT04406272Phase 2Results posted
• INCB7839 in Treating Children With Recurrent/Progressive High-Grade GliomasCompletedNCT04295759Phase 1Results posted
• A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaCompletedNCT04238819Phase 1/2Results posted
• Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent GlioblastomaActive, not recruitingNCT04225039Phase 2Results posted
• Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed GlioblastomaActive, not recruitingNCT04216329Phase 1Results posted
• Neoadjuvant Chemoradiation for Resectable GlioblastomaTerminatedNCT04209790Phase 2Results posted
• First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive GlioblastomaCompletedNCT04116658Phase 1/2Results posted
• Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated GlioblastomaActive, not recruitingNCT04015700Phase 1Results posted
• Study of Pembrolizumab Plus SurVaxM for Glioblastoma at First RecurrenceCompletedNCT04013672Phase 2Results posted
• Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive GlioblastomaTerminatedNCT04006119Phase 2Results posted
• Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGGTerminatedNCT03973918Phase 2Results posted
• Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated GliomaTerminatedNCT03927222Phase 2Results posted
• BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 MutationsCompletedNCT03914742Phase 1/2Results posted
• Solriamfetol in Improving Sleep in Patients With Grade II-IV GliomaTerminatedNCT03868943Phase 2Results posted
• A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for ResectionCompletedNCT03834740Early Phase 1Results posted
• Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)CompletedNCT03797326Phase 2Results posted
• 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation TherapyCompletedNCT03778294Phase 2Results posted
• Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With GlioblastomaCompletedNCT03746080Phase 2Results posted
• Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator PhenotypeActive, not recruitingNCT03718767Phase 2Results posted
• Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBMTerminatedNCT03705351Phase 1Results posted
• A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 MutationCompletedNCT03684811Phase 1/2Results posted
• Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102CompletedNCT03679754Phase 1Results posted
• Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent GlioblastomaCompletedNCT03661723Phase 2Results posted
• Trial of C134 in Patients With Recurrent GBMCompletedNCT03657576Phase 1Results posted
• A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102CompletedNCT03636477Phase 1Results posted
• Standard Chemotherapy vs. Chemotherapy Guided by Cancer Stem Cell Test in Recurrent GlioblastomaCompletedNCT03632135Phase 3Results posted
• Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent MedulloblastomaCompletedNCT03615404Phase 1Results posted

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