ClinicalTrials.gg
RecruitingNCT07599241Updated May 20, 2026

Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver Issues

An interventional study of physical activity and usual care in Subclinical hypothyroïdism, Non-Alcoholic Fatty Liver Disease and Primary Open Angle Glaucoma, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to female participants aged 65 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-05-20.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Mar 2026; still recruiting 7 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
65 Years to 75 Years
Sex
Female
01

Study summary

additive efficacy of physical activity program in hypthyroidism in elder females with glaucoma and fatty liver issues was not investigated

Read the detailed description

hypthyroidism elder females (n=40) with glaucoma and fatty liver issues will randomly divided into group number 1 (n=20) that will recive their levothyroxine and physical activity program on treadmill thrice weehly for 6 month or group number II (n=20) that will receive levothyroxine only

02

Conditions studied

  • Subclinical hypothyroïdism
  • Non-Alcoholic Fatty Liver Disease
  • Primary Open Angle Glaucoma
03

In context

Non-alcoholic Fatty Liver Disease

1,617 studies on the registry are indexed under Non-alcoholic Fatty Liver Disease; 324 are open to participants now.

This study's planned enrollment of 40 is below the median of 60 across 1,176 interventional studies indexed under Non-alcoholic Fatty Liver Disease.

Browse Non-alcoholic Fatty Liver Disease studies →

Lead sponsor

Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years to 75 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • subclinical hypothrodism (significant form)
  • primary opened angle gaulcoma in both eyes with ocular hypertension in both eyes )(high-tension typed glaucoma)
  • fatty liver (non alcholic type)
  • elder females

Exclusion criteria

Exclusion Criteria:

  • respiratory issues
  • cardiac issues
  • renal issues
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    group number 1

    hypthyroidism elder females (n=20) with glaucoma and fatty liver issues recive their levothyroxine and physical activity program on treadmill thrice weekly for 6 month

    Behavioral: physical activity

  • Active comparator
    group number 2

    hypthyroidism elder females (n=20) with glaucoma and fatty liver issues will recive their levothyroxine only

    Other: usual care

Interventions

  • Behavioralphysical activity

    hypthyroidism elder females (n=20) with glaucoma and fatty liver issues that will recive their levothyroxine and physical activity program on treadmill thrice weehly for 6 month

  • Otherusual care

    hypthyroidism elder females (n=20) with glaucoma and fatty liver issues that will recive their levothyroxine only

06

What researchers measure

Primary outcomes

  1. intraocular pressure

    it will be assessed in both eyes

    Time frame: 6 months

Secondary outcomes

  1. body mass index

    it will be assessed on empty stomach and bladder

    Time frame: 6 months

  2. waist circumfrence

    it will be assessed by tape at umblical level

    Time frame: 6 months

  3. systolic blood pressure

    it will be assessed by sphygmomanmometer

    Time frame: 6 months

  4. diastolic blood pressure

    it will be assessed by sphygmomanmometer

    Time frame: 6 months

  5. glaucoma assocaited life quality survey

    it is a questionaire evaluates life quality

    Time frame: 6 months

  6. triglyceridss

    it will be assessed in serum

    Time frame: 6 months

  7. high density lipoproteines

    it will be assesed in serum

    Time frame: 6 months

  8. alanine transamianses

    it will be assessed in serum

    Time frame: 6 months

  9. aspartate trasnamiansses

    it will be assessed in serum

    Time frame: 6 months

  10. physical conclusion of short form survey

    it will assess physical quality of lifes of females

    Time frame: 6 months

  11. Mental conclusion of short form survey

    it will assess physical quality of lifes of females

    Time frame: 6 months

  12. thyroid stimualting horomone

    it will be assessed in serum

    Time frame: 6 months

  13. fasting glycemia value

    it will be assessed in serum

    Time frame: 6 months

07

Study locations

1 of 1 sites recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 20, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07599241
Lead sponsor
Cairo University
Responsible party
Ali Mohamed Ali ismail (lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Cairo University) — Principal investigator
First posted
May 20, 2026
Start date
Mar 15, 2026
Primary completion
Dec 15, 2026 (estimated)
Completion
Dec 15, 2026 (estimated)
Last update
May 20, 2026

Study contacts

Ali MA Ismail, lecturer
Contact
ali.mohamed@pt.cu.edu.eg
01005154209
fatma M Ali
Contact
fatma1995@gmail.com
01031321109
Ali MA Ismail, lecturer
principal investigator · Cairo University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion