An interventional study of mHealth Text Message Program and Usual Care in Hypertension and Primary Hypertension, sponsored by GIFT University. Completed at 1 site in Pakistan. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-26.
Sponsored by GIFT University · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to learn if text messages can help adults with newly diagnosed high blood pressure (hypertension) bring their blood pressure under control. The study took place in primary care clinics in Bangladesh and Pakistan. The main questions it aims to answer are:
Do more participants who get text messages have their blood pressure under control after 6 months? Under control means a top number below 140 and a bottom number below 90.
Do text messages help participants take their blood pressure medicine as prescribed?
Researchers compared a text message program to usual care to see if the text messages work to lower blood pressure. They randomly assigned whole clinics, not individual people, to one of the two groups.
Participants:
Got text messages for 6 months, or got written health materials and usual care. Received daily messages for the first month and fewer after that, if in the text message group. The messages encouraged taking medicine, healthy habits, and checking blood pressure.
Had their blood pressure checked at 9 weeks and at 6 months.
Hypertension is a major risk factor for heart disease and death worldwide, and it can be treated. But many people with hypertension still do not reach healthy blood pressure levels. This trial tests whether a low-cost text message program can help adults with newly diagnosed hypertension reach blood pressure control in routine primary care.
The trial is multicenter and cluster randomized. Researchers randomly assigned whole primary care clinics, rather than individual participants, to the text message program or usual care. Clinics were assigned in a 2:1 ratio, so twice as many clinics offered the text message program as usual care. Participants were followed for 6 months.
Blood pressure control was the main focus because it is the clinical goal of hypertension treatment. The trial also looked at several other measures of how participants did on treatment. These include blood pressure control at an earlier point (9 weeks), how long participants stayed on their medicine, whether treatment worked or failed, how many participants dropped out of follow-up, and deaths.
Because participants in the same clinic may have similar outcomes, the analysis accounts for clustering by clinic.
6,834 studies on the registry are indexed under Hypertension; 971 are open to participants now.
This study's enrollment of 1,295 is above the median of 90 across 5,095 interventional studies indexed under Hypertension.
Browse Hypertension studies →GIFT University is the lead sponsor of 8 studies on the registry; none are open to participants now.
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Exclusion Criteria
Participants receive text messages for 6 months that encourage taking blood pressure medicine, making healthy lifestyle changes, and checking blood pressure. Messages are sent daily for the first month and less often after that. Participants also receive routine hypertension care at their clinic.
Behavioral: mHealth Text Message Program
Participants receive written educational materials about hypertension and routine hypertension care at their clinic for 6 months. They do not receive text messages.
Other: Usual Care
Participants receive text messages on their mobile phones for 6 months. The messages encourage three things: taking blood pressure medicine as prescribed, making healthy lifestyle changes, and checking blood pressure. Messages are sent daily for the first month and less often after that. Participants receive this program in addition to routine hypertension care at their clinic.
Participants receive written educational materials about hypertension and routine hypertension care at their clinic for 6 months. They do not receive text messages.
Blood pressure control at 6 months
Percentage of participants whose blood pressure is under control at 6 months. Control means systolic blood pressure (the top number) below 140 mm Hg and diastolic blood pressure (the bottom number) below 90 mm Hg.
Time frame: 6 months
Blood pressure control at 9 weeks
Percentage of participants whose blood pressure is under control at 9 weeks. Control means systolic blood pressure (the top number) below 140 mm Hg and diastolic blood pressure (the bottom number) below 90 mm Hg.
Time frame: 9 weeks
Treatment adherence
Number of days participants take their blood pressure medicine during the 6-month follow-up.
Time frame: 6 months
Treatment success
Percentage of participants who have treatment success at 6 months.
Time frame: 6 months
Treatment failure
Percentage of participants who have treatment failure during the 6-month follow-up.
Time frame: 6 months
Loss to follow-up
Percentage of participants who stop attending follow-up visits and cannot be assessed during the 6-month follow-up.
Time frame: 6 months
Plan to share: Undecided — The research team has not yet decided whether to share individual participant data (IPD) with other researchers. A decision will be made after the main results are published. Any plan will follow the ethics approvals and consent terms of the participating clinics.
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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GIFT University