ClinicalTrials.gg
Status unknownNCT05663099AEAUpdated Dec 19, 2023

Cauterization of the Anterior Ethmoidal Artery by Transconjunctival Approach

An observational study in Epistaxis, Anterior Ethmoid Artery, sponsored by University Hospital, Strasbourg, France. Status unknown at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-12-19.

Sponsored by University Hospital, Strasbourg, France · Observational

The sponsor has not verified this record recently (last verified Dec 2022), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
20
Ages
18 Years and older
Sex
All
01

Study summary

The incidence of epistaxis varies from 7 to 14% in the general population and represents 30 per 100,000 emergency room admissions in adults. Most nasal bleeding is self-limiting without the need for specific medical treatment. Cauterization under local anesthesia and control of medical comorbidities (arterial hypertension and hemostasis disorders) are effective in most cases. In case of failure of cauterization or in case of more posterior epistaxis, an antero-posterior packing can be put in place for 48 hours. In case of failure or recurrence of packing removal, endoscopic sphenopalatine artery (SPA) ligation or embolization is proposed. In case of persistent epistaxis despite hemostasis of the PSA, ligation of the anterior ethmoidal artery (AEA) is recommended. This artery cannot be embolized because of the risk to the ophthalmic artery. The ligation of the AEA is most often performed via the external paracanthal approach. It can also be performed by endonasal endoscopic approach but involves the performance of an anterior ethmoidectomy, a long surgery with a significant risk of complications. Its identification by the endonasal route is complicated in the event of abundant bleeding. Moreover, its endoscopic cauterization is difficult if the artery is not procidente. The transconjunctival approach avoids a visible scar and the complications of an ethmoidectomy.

Read the detailed description

The objective of the study was to compare the efficacy of transconjunctival and external cauterization of the anterior ethmoidal artery in patients with refractory epistaxis

02

Conditions studied

  • Epistaxis, Anterior Ethmoid Artery

Keywords

  • Epistaxis
  • Anterior Ethmoid Artery
  • Arterial hypertension
  • Hemostasis disorders
  • Endoscopic sphenopalatine artery
  • Endonasal endoscopic
  • Anterior ethmoidectomy
03

In context

Epistaxis

96 studies on the registry are indexed under Epistaxis; 22 are open to participants now.

This study's planned enrollment of 20 is below the median of 71 across 12 observational studies indexed under Epistaxis.

Browse Epistaxis studies →

Lead sponsor

University Hospital, Strasbourg, France is the lead sponsor of 999 studies on the registry; 358 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Adult patient having un persistent epistaxis after meching

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Male or female (age ≥18 years)
  • Persistent epistaxis after meching
  • Having required transconjunctival anterior ethmoidal artery cauterization surgery
  • Subject operated at the University Hospitals of Strasbourg between 01/01/2015 and 01/05/2023
  • Subject not objecting to the reuse of his/her data for scientific research purposes.

Exclusion criteria

Exclusion Criteria:

  • Subject who has expressed opposition to the reuse of his/her data for scientific research purposes.
05

Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
20 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. To retrospectively compare the efficacy of transconjunctival and external cauterization of the anterior ethmoidal artery in patients with refractory epistaxis

    The endpoint is the efficacy of the technique with the presence of postoperative epistaxis recurrence

    Time frame: Files analysed retrospectively from January 01, 2015 to May 01, 2023 will be examined

07

Study locations

1 of 1 sites recruiting
  • Service d'ORL et de Chirurgie Cervico-Faciale - CHU de Strasbourg - France
    Strasbourg, 67091, France
    Recruiting
    • Léa FATH, MD · Contactlea.fath@chru-strasbourg.fr · 33 3 88 12 64 98
    • Léa FATH, MD · Principal investigator
    • Alexandra LEON, MD · Principal investigator
    • Christian DEBRY, MD, PhD · Sub investigator
    • Idir DJENNAOUI, MD · Sub investigator
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Feb 2023 (actual). Primary completion is estimated for Feb 2024, 12 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 14, 2022
First posted
Dec 23, 2022
StartActual
Feb 7, 2023
Primary completionEst.
Feb 2024
CompletionEst.
Feb 7, 2024
Last update
Dec 19, 2023
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Dec 19, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05663099
Responsible party
Sponsor
First posted
Dec 23, 2022
Start date
Feb 7, 2023
Primary completion
Feb 2024 (estimated)
Completion
Feb 7, 2024 (estimated)
Last update
Dec 19, 2023

Study contacts

Léa FATH, MD
Contact
lea.fath@chru-strasbourg.fr
33 3 88 12 64 98

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Dec 2022. You cannot join it, but the record below documents what was studied.

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