Emphysema clinical trials
The registry lists 331 studies for Emphysema across more than 10 countries. 60 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 168
- Recruiting
- 49
- Status unknown
- 42
- Terminated
- 30
- Withdrawn
- 16
- Active, not recruiting
- 13
Phase
- Phase 2
- 55
- Phase 4
- 27
- Phase 3
- 27
- Phase 1
- 24
- Early Phase 1
- 2
Where
- United States
- 126
- Germany
- 50
- United Kingdom
- 47
- Netherlands
- 38
- France
- 27
- Canada
- 19
Who runs them
Aeris Therapeutics (17) · Pulmonx Corporation (12) · University Medical Center Groningen (12) · Boston Scientific Corporation (9) · National Heart, Lung, and Blood Institute (NHLBI) (8) · Heidelberg University (8) · Royal Brompton & Harefield NHS Foundation Trust (8) · Mayo Clinic (7)
Studies
Recruiting first, then most recently updated. Showing 50 of 331 — search for more.
- Gene Therapy for Alpha 1- Antitrypsin DeficiencyRecruitingNCT06996756Phase 11 country
- A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)RecruitingNCT07759245Phase 218 countries
- Global Utilization And Registry Database for Improved preservAtion of doNor LUNGsEnrolling by invitationNCT049302892 countries
- An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe EmphysemaRecruitingNCT06035120Not applicable10 countries
- Zephyr Valve Japan Post-Marketing SurveillanceRecruitingNCT063328851 country
- Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume ReductionRecruitingNCT05257681Not applicable1 country
- A Study of AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD)RecruitingNCT07431112Phase 15 countries
- A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)RecruitingNCT07555483Phase 39 countries
- STRIVE Post-Market Registry StudyRecruitingNCT043022721 country
- Development of a Prediction Score for the Occurrence of Death or Lung Transplantation in Patients With Emphysema Secondary to Alpha-1-anti-tripsin DeficiencyRecruitingNCT077156171 country
- Endobronchial Silicone Valve for Patients With EmphysemaRecruitingNCT07097896Not applicable1 country
- DIVision of the Interlobar Fissure in Patients Who Do Not Respond to Endobronchial Lung Volume ReductionNot yet recruitingNCT07682168Not applicable
- Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® ValvesRecruitingNCT06181357Not applicable1 country
- Improve Muscle Weakness in Patient With COPDNot yet recruitingNCT07649850Not applicable
- A Trial of the Implantable Artificial Bronchus 50 Flex in Patients With Severe EmphysemaRecruitingNCT07086339Not applicable2 countries
- A Multi Center Study Testing a New Implant for Adults With Severe EmphysemaRecruitingNCT07119229Not applicable1 country
- Lung Disease and FLNA MutationsNot yet recruitingNCT07592637Not applicable1 country
- Clinical-ultrasonographic Assessment of Pulmonary EmphysemaRecruitingNCT06533371Not applicable1 country
- Ultrasound and Respiratory Physiological Signals in Lung DiseasesRecruitingNCT06068647Not applicable1 country
- Phase 4, Double-blind Study Evaluating the Response on Computed Tomography (CT) Lung Density Decline Rates of Respreeza / Zemaira Weekly for 3 Years in Adults With alpha1 Antitrypsin Deficiency (AATD)Not yet recruitingNCT07326592Phase 4
- The Italian Registry of Patients With Chronic Obstructive Pulmonary DiseaseEnrolling by invitationNCT066527761 country
- Change in Task-related Oxygen Uptake After EBV TreatmentRecruitingNCT067020721 country
- Analysing Peripheral Skeletal Muscle Function Before and After Endobronchial Valve TreatmentRecruitingNCT060255001 country
- Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3RecruitingNCT06891755Not applicable4 countries
- Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in EmphysemaRecruitingNCT04801108Not applicable1 country
- Ventilation-Perfusion Discrepancy Index Versus Conventional Anatomic-Physiologic Assessment for Target Lung Lobe Selection in Endobronchial Valve Placement: A Multicenter, Randomised Controlled TrialNot yet recruitingNCT07403617Not applicable1 country
- PiMZ Longitudinal Cohort (PiMZ Logic)RecruitingNCT065056031 country
- Lung and Bone Marrow Transplantation for Lung and Bone Marrow FailureRecruitingNCT03500731Phase 1/21 country
- Collection of Airway, Blood and/or Urine Specimens From Subjects for Research StudiesRecruitingNCT017763981 country
- Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPDRecruitingNCT07059637Not applicable1 country
- Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) StudyRecruitingNCT011776181 country
- Emphysema Research Registry and Biosample RepositoryRecruitingNCT003072811 country
- COPD Resources, Education, and Activity Designed for You StudyRecruitingNCT07125053Not applicable1 country
- A Multi-center RCT to Evaluate Subsegmental BTVA Treatment for Severe EmphysemaRecruitingNCT06152107Not applicable1 country
- BENTO - Bronchoscopic Lung Volume Reduction in Severe Emphysema Using ThermoablationRecruitingNCT05717192Not applicable1 country
- Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer ScreeningRecruitingNCT061220771 country
- Exploring Novel Biomarkers for Emphysema DetectionRecruitingNCT058252611 country
- Bronchoscopic Lung Volume Reduction in Management of Localized EmphysemaRecruitingNCT06629558Not applicable1 country
- Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled BreathRecruitingNCT065284181 country
- Safety and Efficacy of Endobronchial Valve for Bronchoscopic Lung Volume Reduction Surgery: a Prospective Pilot StudyRecruitingNCT06349174Not applicable1 country
- Post-Market BTVA RegistryRecruitingNCT033184063 countries
- Utilising Hull Lung Health Study Data to Investigate the Performance of TidalSense Diagnostic Algorithms to Identify COPD and Pre-COPD Among Participants in the FRONTIER Programme.Not yet recruitingNCT06788613
- Characterizing Matrix Metalloproteinase-12 (MMP12) in SputumRecruitingNCT047613931 country
- DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.RecruitingNCT066903851 country
- Efficacy and Safety of Transbronchial Bronchoscopic Thermal Vapor Ablation (BTVA) in Heterogeneous EmphysemaNot yet recruitingNCT06642038
- Telehealth and Onsite Maintenance Exercise in Chronic Lung DiseaseRecruitingNCT06304207Not applicable1 country
- Using Artificial Intelligence for the Detection of Respiratory Diseases Associated With PollutionEnrolling by invitationNCT065121421 country
- Biological Investigation of Explanted Endobronchial Lung Valves StudyRecruitingNCT042145871 country
- Bronchoscopic EmphysemA Treatment in THE NetherLandsRecruitingNCT028156831 country
- Magnetic Resonance Lung Function Imaging Study of Pulmonary Fibrosis Combined With Emphysema SyndromeRecruitingNCT064315551 country