Edema clinical trials
The registry lists 566 studies for Edema across more than 10 countries. 95 are recruiting or about to start. 253 of them are mainly about Edema (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
ClinicalTrials.gov finds 2,448 studies for Edema. How that becomes 566 here
This page counts the studies the registry files under Edema, and those it files under no condition that list Edemathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 2,448Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −1,226List Edema as a condition, but the registry did not file them under itMost often written as “Diabetic Macular Edema” (468), “Macular Edema” (206), and “Pulmonary Edema” (60). The registry filed 359 of them under no condition at all, and the others under other conditions only, most often Macular Edema (334) and Diabetic Retinopathy (159).
- −656Match it another way310 name it in the title, 150 in a keyword, and 196 by a synonym or other text the search reads.
- 566The count on this page68 of them list Edema in their own words; the registry filed them under no condition.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Bezmialem Vakif University (7) · Church & Dwight Company, Inc. (6) · University of Nove de Julho (6) · Hospices Civils de Lyon (6) · University of Aarhus (5) · Medical University of Vienna (5) · Celtic Pharma Development Services (5) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (5)
What is being tested here
Drugs under test in Edema studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Furosemide | 6 | 4 | 14 |
| Dexamethasone | 2 | 1 | 7 |
| Metolazone | 2 | 0 | 3 |
| Neridronic acid | 2 | 2 | 2 |
| Acetazolamide | 1 | 0 | 4 |
| Albumins | 1 | 1 | 4 |
| Triamcinolone | 1 | 2 | 4 |
| Triamcinolone Acetonide | 1 | 2 | 3 |
| Methylprednisolone | 1 | 0 | 3 |
| Dexamethasone phosphate | 1 | 0 | 2 |
Drug classes tested here Diuretics 7 open · Loop diuretics 6 open · Corticosteroids 3 open · Thiazide diuretics 2 open · Angiogenesis inhibitors 14
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks · Phase 3 · Octapharma
- Nov 2026Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
- Nov 2026Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS) · Indiana University
- Nov 2026Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure · University of Florida
- Nov 2026Proactive Hemodynamic Management During Cytoreductive Surgery and HIPEC · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Nov 2026Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis Fractures · Nishtar Medical University
- Dec 2026Comparison of the Effects of Kinesio Taping and Compression Bandaging on Edema, Range of Motion, Upper Extremity Function, and Grip Strength in Patients With Breast Cancer-Related Lymphedema · Halic University
- Dec 2026Electric Cardiometry-Guided Standard Versus Restricted Fluid Therapy In Robotic Prostaectomy · Nazmy Edward Seif
- Dec 2026COMPARISON OF BANDAGE IN HAND EDEMA · Regione del Veneto - AULSS n. 7 Pedemontana
- Dec 2026Timing of Renal Replacement Therapy in the Critically Ill Patients · Karolinska University Hospital
Who these studies take
Of the 56 Edema studies recruiting now, 34 (61%) set no upper age limit and 16 (29%) stop at 75 or younger. 8 (14%) take children under 18. 4 (7%) are for women only and 1 (2%) for men only; 4 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 7 (13%) | 6 (11%) |
| 18 | 52 (93%) | 48 (86%) |
| 30 | 52 (93%) | 48 (86%) |
| 40 | 50 (89%) | 48 (86%) |
| 50 | 48 (86%) | 46 (82%) |
| 65 | 47 (84%) | 45 (80%) |
| 75 | 42 (75%) | 40 (71%) |
| 85 | 37 (66%) | 35 (63%) |
Across all 566 studies, recruiting or not: 33% stop at 75 or younger and 28% at 65; 12% take children; 7% are for women only and 2% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Edema studies take
Of 28 phase 4 interventional studies under Edema, half reached primary completion within 30 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 19 mo13–31 · 14 studies | — | — |
| Phase 4 | 30 mo12–74 · 28 studies | — | — |
| Interventional, no phase | 11 mo6–24 · 168 studies | — | 11 mo6–24 · 153 studies |
| Observational | 23 mo7–47 · 85 studies | — | 21 mo7–39 · 76 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting3
- Dry Weight Reduction Intervention Via Extra UltrafiltrationOct 30, 2026NCT07637110
- Using Bioimpedance Analysis to Monitor Fluid Status in ChildrenOct 26, 2026NCT07834710
- Phase 3, Open-Label Extension Study of AMBTX-01 (Neridronate) for Complex Regional Pain Syndrome Type 1Oct 16, 2026NCT07857733
Stopped1
- Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg PositioningWithdrawnNov 2, 2026NCT06418022
Newly registered3
- Comparison of Reliability, Time Cost, and Participant Comfort of Lymphedema Assessments in Upper ExtremityNov 6, 2026NCT07921290
- Comparison of the Effects of Kinesio Taping and Compression Bandaging on Edema, Range of Motion, Upper Extremity Function, and Grip Strength in Patients With Breast Cancer-Related LymphedemaNov 5, 2026NCT07919093
- Bioimpedance and Multiparametric Ultrasound-Guided Fluid Management After Kidney TransplantationOct 30, 2026NCT07905963
Studies
Recruiting first, then most recently updated. Showing 50 of 566. Browse all 566 → or search them.
- Screening For BCRL In Targeted Therapy For Breast CancerRecruitingNCT051428001 country
- Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema AttacksRecruitingNCT06361537Phase 313 countries
- Using Bioimpedance Analysis to Monitor Fluid Status in ChildrenRecruitingNCT078347101 country
- Comparison of Reliability, Time Cost, and Participant Comfort of Lymphedema Assessments in Upper ExtremityNot yet recruitingNCT07921290
- Comparison of the Effects of Kinesio Taping and Compression Bandaging on Edema, Range of Motion, Upper Extremity Function, and Grip Strength in Patients With Breast Cancer-Related LymphedemaEnrolling by invitationNCT07919093Not applicable1 country
- Early Deresuscitation Strategy Driven by Tissue Perfusion in Renal Replacement Therapy in Patients With Acute Renal FailureRecruitingNCT05817539Not applicable1 country
- Dry Weight Reduction Intervention Via Extra UltrafiltrationRecruitingNCT07637110Not applicable1 country
- Bioimpedance and Multiparametric Ultrasound-Guided Fluid Management After Kidney TransplantationNot yet recruitingNCT07905963Not applicable
- Capital Offload-ShockNot yet recruitingNCT07756801Phase 41 country
- Diuretic Tuner Clinical Decision SupportRecruitingNCT04759274Not applicable1 country
- Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)RecruitingNCT07210515Phase 31 country
- Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0Enrolling by invitationNCT0682311533 countries
- Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)RecruitingNCT070599622 countries
- Phase 3, Open-Label Extension Study of AMBTX-01 (Neridronate) for Complex Regional Pain Syndrome Type 1RecruitingNCT07857733Phase 31 country
- Blood Volume Monitoring Via Critline in Volume Overload: Hospitalization and ReadmissionEnrolling by invitationNCT078668721 country
- A Study of JMKX003142 Tablet to Treat Renal EdemaNot yet recruitingNCT07841093Phase 31 country
- Boston Medical Center Ultrasound Decongestion Study in Heart FailureNot yet recruitingNCT07096726Not applicable1 country
- Perioperative Photobiomodulation in Facial Plastic SurgeryNot yet recruitingNCT07846631Not applicable1 country
- Molecular Underpinnings of Heart Failure, Integrative Multi-Omics, and Non-Coding RNA ProfilingRecruitingNCT071580861 country
- The Effects of Manual Lymphatic Drainage and Self-Manual Lymphatic DrainageNot yet recruitingNCT07814807Not applicable1 country
- Characterization of Peri-Hemorrhagic Cerebral Edema Using Synthetic Sodium Imaging With 7-Tesla and 3-Tesla MRINot yet recruitingNCT07789990Not applicable
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)RecruitingNCT042784042 countries
- Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care PathwaysEnrolling by invitationNCT077759761 country
- Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard CareNot yet recruitingNCT07719270Not applicable1 country
- The FILTRATE Trial: High-Rate Ultrafiltration for Intravascular CongestionRecruitingNCT07705269Not applicable1 country
- Volume Removal Intolerance During Net Ultrafiltration in Acute Kidney Injury PatientsRecruitingNCT076435977 countries
- Infusion of Furosemide to Improve Diuretic Efficiency in Acute Heart FailureRecruitingNCT07577596Phase 41 country
- Euvolemia-Based Assessment of Pulmonary Hypertension in Stable Hemodialysis PatientsNot yet recruitingNCT076767861 country
- Bumetanide vs. Furosemide in CirrhosisRecruitingNCT06941415Phase 31 country
- "Effect of Albumin Combined With Furosemide in Critically Ill Patients With Fluid Overload: Impact on Urine Output and Renal Function"RecruitingNCT07417969Not applicable1 country
- Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart FailureRecruitingNCT06979726Phase 41 country
- Electric Cardiometry-Guided Standard Versus Restricted Fluid Therapy In Robotic ProstaectomyRecruitingNCT07626151Not applicable1 country
- SURE-HF: Urinary Sodium-Guided Diuretic Therapy in Heart FailureNot yet recruitingNCT07631780Not applicable1 country
- Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit.RecruitingNCT04180397Phase 49 countries
- A Clinical Study Comparing Ankle Swelling Caused by Two Different Blood Pressure Medications, Levamlodipine and Amlodipine, in Post-menopausal Women With Mild High Blood Pressure.Not yet recruitingNCT07618806Phase 3
- Proactive Hemodynamic Management During Cytoreductive Surgery and HIPECRecruitingNCT07070973Not applicable1 country
- Measuring Fluid Buildup in Cancer PatientsRecruitingNCT074436181 country
- Comparison of Submucosal Dexamethasone and Methylprednisolone in Postoperative Sequelae of Parasymphsis FracturesRecruitingNCT07208799Phase 21 country
- Detecting the Undetected: Heart Failure Screening at the Lymphoedema Point of CareNot yet recruitingNCT074988681 country
- Renal and Hepatic Abnormal Doppler Patterns in TraumaRecruitingNCT074925111 country
- Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single CentreRecruitingNCT07033039Not applicable1 country
- ReDS-guided Decongestion Strategy in Patients Hospitalized for Heart FailureRecruitingNCT07484009Not applicable1 country
- Transitional Care Program for Fluid Overload in CirrhosisRecruitingNCT06174272Not applicable1 country
- Care Bundle for Prevention of Skin Complications and Edema in Restrained PatientsNot yet recruitingNCT07442344Not applicable1 country
- Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand SyndromeRecruitingNCT07428811Not applicable1 country
- Focused Echocardiography for Primary Care PhysiciansNot yet recruitingNCT07427303Not applicable
- Infant Massage for Lymphedema and Comfort in Preterm NewbornsNot yet recruitingNCT07418814Not applicable
- Consistency of Fluid Tolerance Evaluation Methods and Their Correlation With Clinical Outcomes in Patients With ShockEnrolling by invitationNCT073737171 country
- Combined Exercise Effects in Breast Cancer-related LymphedemaNot yet recruitingNCT07365618Not applicable1 country
- Timing and Dose of Fluid Deresuscitation in Critically Ill PatientsRecruitingNCT072756581 country