An observational study in Shock, sponsored by Southeast University, China. Enrolling by invitation at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-01-28.
Sponsored by Southeast University, China · Observational
This study aims to explore the feasibility and scientific validity of carotid-jugular Doppler in evaluating volume tolerance in shock patients (with the VExUS score as an important reference standard), and to conduct an in-depth analysis of the correlation between its monitoring indicators and patient prognosis.The primary endpoint is comparison of the agreement between hands-free carotid-jugular Doppler and the VExUS score in evaluating volume tolerance.The secondary endpoint is correlation between volume tolerance assessed by hands-free carotid-jugular Doppler and the clinical outcomes of shock patients.
487 studies on the registry are indexed under Shock; 107 are open to participants now.
This study's planned enrollment of 45 is below the median of 100 across 247 observational studies indexed under Shock.
Browse Shock studies →Southeast University, China is the lead sponsor of 168 studies on the registry; 45 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients admitted to the ICU
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hands-free Carotid Artery and Vein Doppler Parameters
Elevate the patient's upper body to 45°, keep the legs flat, place the long axis of the probe perpendicular to the carotid vessels (with the probe height not exceeding the upper edge of the thyroid cartilage), locate the optimal signals of the common carotid artery and internal jugular vein waveforms, and then fix the probe.
Time frame: Time of shock in ICU within 3 days
PiCCO
Inject cold saline through central venous catheterization, sense temperature changes via arterial catheter, and obtain hemodynamic parameters such as cardiac output by combining thermodilution and pulse contour analysis.
Time frame: Time of shock in ICU within 3 days
Venous Excess Ultrasound Score
Evaluate the diameter, waveform, etc. of the inferior vena cava, hepatic veins, portal vein, and intrarenal veins sequentially via ultrasound, and comprehensively derive a grade ranging from 0 to 3.Grade 0: No congestion; Grade 1: Mild congestion; Grade 2: Moderate congestion; Grade 3: Severe congestion.
Time frame: Time of shock in ICU within 3 days
Bioelectrical Impedance Analysis
Attach electrodes to the patient's limbs, input basic information, measure impedance of multiple parts with multi-frequency technology, and quickly obtain parameters such as body composition.
Time frame: Time of shock in ICU within 3 days
Duration of shock
Time of shock in ICU within 28 days
Time frame: Time of shock in ICU within 28 days
Duration of Mechanical Ventilation
Duration of Mechanical Ventilation During ICU Admission
Time frame: up to 24 weeks
Total Length of Hospital Stay
Total Length of Hospital Stay
Time frame: up to 24 weeks
Length of ICU stay
Length of ICU stay
Time frame: up to 24 weeks
mortality of 28 days
Incidence of death during 28 days
Time frame: Incidence of death during 28 days
In-hospital Mortality
In-hospital Mortality
Time frame: up to 24 weeks
Vasoactive Agent Dosage
Vasoactive Agent Dosage During ICU Admission
Time frame: up to 24 weeks
Time without vasoactive agents within 28 days
Time without vasoactive agents within 28 days
Time frame: Time without vasoactive agents within 28 days
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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