Dystonia clinical trials
The registry lists 213 studies for Dystonia across more than 10 countries. 54 are recruiting or about to start. 92 of them are mainly about Dystonia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Torticollis too: 316 studies, 70 open.
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Status
Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (32) · University of Florida (13) · University of Southern California (5) · University of California, San Francisco (5) · University Health Network, Toronto (5) · Institut National de la Santé Et de la Recherche Médicale, France (4) · Mayo Clinic (4) · Emory University (4)
What is being tested here
Drugs under test in Dystonia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Efficacy and Safety of Radiofrequency Pallidotomy in the Management of Dystonia · All India Institute of Medical Sciences, New Delhi
- Jan 2027Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia · Radboud University Medical Center
- Feb 2027Cortical-Basal Ganglia Speech Networks · Massachusetts General Hospital
- Feb 2027Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb Dystonia · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Mar 2027Effects of Stimulation Patterns of Deep Brain Stimulation · Duke University
- Mar 2027A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia · Vima Therapeutics
- Mar 2027The Effects of Waning of Botulinum Toxin in the Treatment of Cervical Dystonia · Western University, Canada
- Jun 2027Surgery of Dystonia · Sohag University
- Jul 2027Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders · State University of New York at Buffalo
- Aug 2027Physiological Brain Atlas Development · Vanderbilt University Medical Center
Who these studies take
Of the 41 Dystonia studies recruiting now, 19 (46%) set no upper age limit and 10 (24%) stop at 75 or younger. 18 (44%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (15%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 16 (39%) | 16 (39%) |
| 18 | 37 (90%) | 37 (90%) |
| 30 | 35 (85%) | 35 (85%) |
| 40 | 35 (85%) | 35 (85%) |
| 50 | 35 (85%) | 35 (85%) |
| 65 | 35 (85%) | 35 (85%) |
| 75 | 33 (80%) | 33 (80%) |
| 85 | 25 (61%) | 25 (61%) |
Across all 213 studies, recruiting or not: 31% stop at 75 or younger and 17% at 65; 37% take children; 0% are for women only and 0% for men only; 23% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Dystonia studies take
Of 49 interventional studies with no phase under Dystonia, half reached primary completion within 50 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 50 mo26–75 · 49 studies | — | 50 mo26–75 · 48 studies |
| Observational | 72 mo58–188 · 27 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 50 of 213. Browse all 213 → or search them.
- Deep Brain Stimulation Surgery for Movement DisordersRecruitingNCT01581580Not applicable1 country
- Impact of rTMS on Abnormal Cortical fMRI in Patients With DystoniaRecruitingNCT07626216Not applicable1 country
- Accelerating TMS for Cervical DystoniaEnrolling by invitationNCT06328114Phase 21 country
- Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb DystoniaRecruitingNCT07168850Not applicable1 country
- Intrathecal Baclofen and Pediatric DystoniaRecruitingNCT06606574Not applicable1 country
- A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated DystoniaRecruitingNCT07304089Phase 22 countries
- Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric DystoniaRecruitingNCT07325175Not applicable1 country
- Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNSRecruitingNCT065536252 countries
- Vercise™ DBS Dystonia Prospective StudyRecruitingNCT0268612512 countries
- Intraoperative Microelectrode Recordings Using MAVEN Compared to Standard Recording ApparatusesRecruitingNCT078686141 country
- Deep Brain Stimulation (DBS) Retrospective Outcomes StudyRecruitingNCT036646096 countries
- A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)Not yet recruitingNCT06792500Phase 1/21 country
- DaxibotulinumtoxinA for BlepharospasmRecruitingNCT07489430Phase 21 country
- Dystonia Genotype-Phenotype CorrelationRecruitingNCT034280091 country
- Physiological Brain Atlas DevelopmentRecruitingNCT005750811 country
- LIFUS For Neurological DisordersRecruitingNCT07417280Not applicable1 country
- Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral PalsyRecruitingNCT06554288Phase 11 country
- Long-read Genome Sequencing for the Molecular Diagnosis of DystoniaRecruitingNCT06999096Not applicable1 country
- Deep Brain Stimulation (DBS) MatchMakerEnrolling by invitationNCT069128411 country
- Effects of Stimulation Patterns of Deep Brain StimulationEnrolling by invitationNCT02553525Not applicable1 country
- Multimodal Investigation of Cortico-Basal Ganglia-Thalamo-Cortical Network Dynamics in Dystonic Patients With Deep Brain StimulationRecruitingNCT067169831 country
- Cortical-Basal Ganglia Speech NetworksRecruitingNCT04286308Not applicable1 country
- A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia SyndromesRecruitingNCT065856051 country
- A Multicenter Pediatric Deep Brain Stimulation RegistryRecruitingNCT065856181 country
- Sleep-specific DBS Therapy in Parkinson's DiseaseRecruitingNCT05962489Not applicable1 country
- Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke PatientsNot yet recruitingNCT074293831 country
- Abbott DBS Post-Market Study of Outcomes for Indications Over TimeRecruitingNCT040718479 countries
- Predicting DBS Outcomes in Dystonia Using Wearable Gait SensorsRecruitingNCT073236021 country
- Local Field Potentials in DystoniaRecruitingNCT073091331 country
- Brain Networks in DystoniaRecruitingNCT030429621 country
- Deep Brain Stimulation in Laryngeal Dystonia and Voice TremorRecruitingNCT05150093Not applicable1 country
- Imaging Genetics of Laryngeal DystoniaRecruitingNCT030429751 country
- Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated DystoniaRecruitingNCT05317390Not applicable1 country
- Chronic Outcome Monitoring for DBS in DystoniaRecruitingNCT072445491 country
- Observational Study on "Functional Overlay" in Patients With Movement DisordersRecruitingNCT059436521 country
- Deep Anterior Cerebellar Stimulation in Treatment of Poststroke Spasticity and Motor Function Impairment.RecruitingNCT07190092Not applicable1 country
- Surgery of DystoniaNot yet recruitingNCT07140302Not applicable1 country
- Effects of Exercise on Dystonia PathophysiologyRecruitingNCT05663840Not applicable1 country
- Deep Brain Stimulation for Idiopathic Craniofacial Dystonia: GPi or STNRecruitingNCT05416905Not applicable1 country
- The Effects of Waning of Botulinum Toxin in the Treatment of Cervical DystoniaNot yet recruitingNCT06886750Phase 4
- Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover TrialRecruitingNCT05097001Not applicable1 country
- Video-supervised Motor and Awareness Training in Writer's CrampRecruitingNCT04611009Phase 21 country
- The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related DisordersRecruitingNCT06174948Not applicable1 country
- Register for Patients With Thyroid Hormone Resistance.RecruitingNCT065660661 country
- Differences in Brain Network Mechanisms Between STN and GPi Deep Brain Stimulation in the Treatment of Craniocervical DystoniaRecruitingNCT06480188Not applicable1 country
- Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) SurgeryEnrolling by invitationNCT023202661 country
- Strategy to Adapt Botulinum Toxin Doses in DystoniaNot yet recruitingNCT06386848
- Lesioning Procedures for Movement DisordersNot yet recruitingNCT063522681 country
- Investigating LFP Correlates of TUS in Patients With Movement DisordersRecruitingNCT05965960Not applicable1 country
- Efficacy and Safety of Radiofrequency Pallidotomy in the Management of DystoniaNot yet recruitingNCT06038097Not applicable1 country