Central Nervous System Infections clinical trials
The registry lists 41 studies for Central Nervous System Infections across more than 10 countries. 9 are recruiting or about to start. 18 of them are mainly about Central Nervous System Infections (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its 16 narrower conditions too, such as Poliomyelitis: 1,237 studies, 240 open.
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Who runs them
JN-International Medical Corporation (2) · Beneficência Portuguesa de São Paulo (2) · IRCCS San Raffaele (2) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · Delve Bio, Inc. (1) · University Hospital, Ghent (1) · European Society for Blood and Marrow Transplantation (1) · Wei Zhao (1)
What is being tested here
Drugs under test in Central Nervous System Infections studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation · Tan Tock Seng Hospital
- Jun 2027Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous System (CNS) Infection · Delve Bio, Inc.
Who these studies take
Of the 5 Central Nervous System Infections studies recruiting now, 3 (60%) set no upper age limit and 1 (20%) stop at 75 or younger. 1 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (20%) | 1 (20%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 4 (80%) | 4 (80%) |
| 85 | 3 (60%) | 3 (60%) |
Across all 41 studies, recruiting or not: 34% stop at 75 or younger and 32% at 65; 44% take children; 0% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
- Tissue Penetration of Paracetamol in Pediatric Intensive Care PatientsNov 4, 2026NCT07916831
Studies
Recruiting first, then most recently updated. Showing 41 of 41. search them.
- Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous System (CNS) InfectionRecruitingNCT07435649Not applicable1 country
- A Trial of ALN-6457 in Adult Participants With Symptomatic Prion Disease (PrD)Not yet recruitingNCT07832370Phase 1/2
- Safety and Efficacy of Ventricular Irrigation for VentriculitisRecruitingNCT06358209Not applicable1 country
- INfectious DIsease REgistry BIObankRecruitingNCT064180481 country
- Safety, Pharmacokinetics and Efficacy of BV100 Plus Low Dose Polymyxin B Plus Ceftazidime/Avibactam, or Plus Cefiderocol in Patients With Pulmonary and Extrapulmonary Infections Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus ComplexNot yet recruitingNCT07431307Phase 2
- Comparing Tigecycline Vs. Colistimethate in CNS InfectionsNot yet recruitingNCT06702943
- Central Nervous System Infections in DenmarkRecruitingNCT034184411 country
- Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD)Not yet recruitingNCT06412549Not applicable
- Economic Impact of mNGS on Diagnosis of Post-neurosurgical Central Nervous System InfectionRecruitingNCT05887037Not applicable1 country
- Tissue Penetration of Paracetamol in Pediatric Intensive Care PatientsCompletedNCT079168311 country
- Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological RehabilitationActive, not recruitingNCT067049971 country
- National Study on Listeriosis and ListeriaCompletedNCT015205971 country
- Viral Infections of the Central Nervous System: Diagnosis and Clinical OutcomeActive, not recruitingNCT073581171 country
- Molecular Panel Evaluation for Diagnosis of Infections of the Central Nervosous SystemCompletedNCT067205191 country
- Topical Vancomycin for Neurosurgery Wound ProphylaxisCompletedNCT02284126Phase 31 country
- Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)CompletedNCT070440371 country
- Central Nervous System Disorders Following Hematopoietic Stem Cell TransplantationCompletedNCT0473778512 countries
- A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs ControlCompletedNCT04796935Not applicable1 country
- Device-related Central Nervous System Infections in Adult Intensive Care Units in BrazilActive, not recruitingNCT064125231 country
- Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With EncephalitisCompletedNCT02308982Phase 31 country
- Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of CareCompletedNCT014313265 countries
- Determination of COVID-19 Related Virus in Central Nervous SystemStatus unknownNCT047757841 country
- Brazil ICU Encephalitis SurveillanceCompletedNCT053705731 country
- The Role of Serum Procalcitonin in Diagnosis and Detection of Outcome of Acute Bacterial Meningitis in ChildernStatus unknownNCT04929925
- Venezuelan Equine Encephalitis Monovalent Virus-Like Particle VaccineStatus unknownNCT03776994Phase 11 country
- Meningitis Encephalitis: a Metagenomics-Based Etiology & Epidemiology ResearchStatus unknownNCT047248761 country
- Protecting Brains and Saving Futures - the PBSF ProtocolStatus unknownNCT037864971 country
- Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized PatientsStatus unknownNCT042295111 country
- Ceftriaxone as Home IV for Staph InfectionsStatus unknownNCT04141787Phase 41 country
- A Study the Population Pharmacokinetics of Children of Infectious Disease in Central Nervous SystemStatus unknownNCT039609051 country
- CNS Infections Effect on the Inner EarStatus unknownNCT037155691 country
- Daptomycin in Pediatric Patients With Bacterial MeningitisTerminatedNCT01522105Phase 11 country
- Vietnam Cryptococcal Retention in Care Study Version 1.0Status unknownNCT023346701 country
- Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNSCompletedNCT02452216Early Phase 11 country
- Singapore Neurologic Infections ProgramStatus unknownNCT020176651 country
- Meropenem Penetration Across BBB in Patients With CNS Infection and Optimization of Meropenem TreatmentCompletedNCT02506686Phase 4
- Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.)WithdrawnNCT01923376Not applicable1 country
- Immunogenicity and Safety of Group A, C, Y & W-135 Meningococcal Polysaccharide Diphtheria Toxoid Conjugate VaccineCompletedNCT01897402Phase 21 country
- Safety Study of Group A, C, Y & W-135 Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine for MeningitisCompletedNCT01482052Phase 11 country
- Lymphocytic Herpesviruses and Cerebrospinal Fluid Polymerase Chain Reaction (PCR)Status unknownNCT014388791 country
- Long Term Outcomes of EV71 CNS InfectionStatus unknownNCT001723931 country