Meningitis, Cryptococcal clinical trials
The registry lists 53 studies for Meningitis, Cryptococcal across more than 10 countries. 6 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-10.
Status
- Completed
- 35
- Status unknown
- 10
- Recruiting
- 4
- Terminated
- 2
- Enrolling by invitation
- 1
- Not yet recruiting
- 1
Phase
- Phase 2
- 12
- Phase 3
- 8
- Phase 4
- 5
- Phase 1
- 5
- Early Phase 1
- 1
Where
- United States
- 23
- Uganda
- 10
- Zimbabwe
- 4
- Vietnam
- 4
- South Africa
- 3
- Thailand
- 3
Who runs them
Pfizer (11) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · University of Minnesota (5) · National Hospital for Tropical Diseases, Hanoi, Vietnam (3) · University of Zimbabwe (2) · ANRS, Emerging Infectious Diseases (2) · Matinas BioPharma Nanotechnologies, Inc. (2) · Novartis Pharmaceuticals (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 53 — search for more.
- Fungal Infection SusceptibilityRecruitingNCT000013521 country
- Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low TitersNot yet recruitingNCT07743593Phase 31 country
- Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaRecruitingNCT008672691 country
- Platform Trial For Cryptococcal Meningitis (PLATFORM-CM)RecruitingNCT06666322Phase 2/31 country
- Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal AntigenemiaRecruitingNCT03945448Phase 2/31 country
- Amphotericin B for Non-HIV Cryptococcal Meningitis PatientsEnrolling by invitationNCT06178627Phase 41 country
- Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal MeningitisCompletedNCT06414512Phase 21 country
- Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT)CompletedNCT04031833Phase 1/21 country
- Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico CityStatus unknownNCT05685641Not applicable1 country
- Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3Status unknownNCT05541107Phase 3
- Clinical Study of ABCD in the Treatment of Cryptococcal MeningitisStatus unknownNCT05471063Not applicable1 country
- Driving Reduced AIDS-associated Meningo-encephalitis MortalityCompletedNCT03226379Not applicable3 countries
- Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal MeningitisCompletedNCT045324631 country
- The Lived Experience of Participants in an African Randomised TrialCompletedNCT042962923 countries
- High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected IndividualsCompletedNCT00885703Phase 1/28 countries
- A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal MeningitisCompletedNCT00000639Not applicable1 country
- Dexamethasone in Cryptococcal MeningitisCompletedNCT00000776Phase 22 countries
- Three Induction Treatments on Cryptococcal MeningitisStatus unknownNCT04072640Early Phase 11 country
- Cryptococcal Optimal ART Timing TrialCompletedNCT01075152Phase 42 countries
- Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal MeningitisCompletedNCT01802385Phase 31 country
- Operational Research for Cryptococcal Antigen ScreeningCompletedNCT01535469Phase 41 country
- Treatment With Tamoxifen in Cryptococcal MeningitisCompletedNCT03112031Phase 21 country
- CryptoART Study: Decreasing Mortality Associated With Initiation of Antiretroviral Therapy in Sub-Saharan AfricaCompletedNCT024341721 country
- Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial ReportCompletedNCT02955862Phase 11 country
- Pre-Antiretroviral Therapy (ART) Cryptococcal Antigen Screening in AIDSStatus unknownNCT02624453Not applicable1 country
- Vietnam Cryptococcal Retention in Care Study Version 1.0Status unknownNCT023346701 country
- Vietnam Cryptococcal Retention in Care Study - Version 2.1Status unknownNCT032674071 country
- Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in AfricaCompletedNCT00830856Not applicable1 country
- Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan AfricaStatus unknownNCT01715922Phase 2/32 countries
- Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal MeningitisStatus unknownNCT02686853Phase 4
- Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRCCompletedNCT01589289Phase 31 country
- Liposomal Amphotericin B for the Treatment of Cryptococcal MeningitisStatus unknownNCT02136030Not applicable1 country
- Clinical Outcomes of Cryptococcal Meningitis Among HIV-infected Patients in the Era of Antiretroviral TherapyCompletedNCT020985251 country
- Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated MeningitisCompletedNCT00145249Phase 22 countries
- Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal MeningitisCompletedNCT00976040Phase 41 country
- Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal MeningitisCompletedNCT00000708Not applicable1 country
- Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDSCompletedNCT00001017Phase 31 country
- Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal MeningitisCompletedNCT00012467Phase 22 countries
- Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDSTerminatedNCT00847678Phase 21 country
- Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDSTerminatedNCT00324025Phase 21 country
- A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin BCompletedNCT00002306Not applicable1 country
- A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.CompletedNCT00002113Not applicable1 country
- Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency SyndromeCompletedNCT00002019Not applicable1 country
- The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal MeningitisCompletedNCT00002316Phase 11 country
- Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal MeningitisCompletedNCT00002040Not applicable1 country
- A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal MeningitisCompletedNCT00002068Not applicable2 countries
- A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDSCompletedNCT00002294Not applicable1 country
- Pilot Study of Oral Fluconazole in the Treatment of Acute Cryptococcal MeningitisCompletedNCT00002076Not applicable1 country
- Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency SyndromeCompletedNCT00002074Not applicable2 countries
- A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal MeningitisCompletedNCT00002305Not applicable2 countries