Carotid Stenosis clinical trials
The registry lists 364 studies for Carotid Stenosis across more than 10 countries. 85 are recruiting or about to start. 269 of them are mainly about Carotid Stenosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Status
Who runs them
Xuanwu Hospital, Beijing (11) · Second Affiliated Hospital, School of Medicine, Zhejiang University (6) · Beijing Tiantan Hospital (6) · Columbia University (5) · Peking Union Medical College Hospital (5) · National Heart, Lung, and Blood Institute (NHLBI) (5) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (5) · Mayo Clinic (5)
What is being tested here
Drugs under test in Carotid Stenosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Evolocumab | 1 | 0 | 3 |
| Rivaroxaban | 1 | 0 | 2 |
| Aspirin | 1 | 0 | 2 |
| Secukinumab | 1 | 0 | 1 |
| Alirocumab | 1 | 1 | 1 |
| Atorvastatin | 0 | 1 | 4 |
| Clopidogrel | 0 | 0 | 3 |
| Ticagrelor | 0 | 0 | 2 |
| Remifentanil | 0 | 0 | 2 |
| Dexmedetomidine | 0 | 0 | 2 |
Drug classes tested here PCSK9 inhibitors 2 open · Statins 6 · P2Y12 inhibitors 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Monitoring of Brain Metabolites Using Proton and Deuterium MR Techniques · Insel Gruppe AG, University Hospital Bern
- Nov 2026Carotid Revascularization With MicroNet Covered Stent Comparing Early Neurological Outcomes With Distal Versus Proximal EPS · Meshalkin Research Institute of Pathology of Circulation
- Nov 2026A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach · InspireMD
- Dec 2026Predictive Value of Neovascularization Within Asymptomatic Carotis Stenosis on CEUS · University Hospital, Basel, Switzerland
- Dec 2026Perioperative GFAP and Neurological Complications After Carotid Endarterectomy · Filiz Ata
- Dec 2026A Randomized Trial of Carotid Artery Stenting With Balloon Guide Catheter · Hebei General Hospital
- Dec 202618F FDG and 68Ga FAPI PET/MR Imaging of Carotid Artery Plaque Vulnerability: A Clinical Study in Carotid Artery Plaque Patients · Ruijin Hospital
- Dec 2026Plaque and Brain Inflammation in Symptomatic Carotid Stenosis: Role of the Ficolin-2 · Hospices Civils de Lyon
- Dec 2026Carotid Revascularization for Radiation Induced Carotid Artery Stenosis · Xuanwu Hospital, Beijing
- Jan 2027Impact of Significant Carotid Stenosis on Retinal Perfusion Measured Via Automated Retinal Oximetry · University Hospital Olomouc
Who these studies take
Of the 60 Carotid Stenosis studies recruiting now, 38 (63%) set no upper age limit and 0 (0%) stop at 75 or younger. 4 (7%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (7%) | 4 (7%) |
| 18 | 46 (77%) | 46 (77%) |
| 30 | 48 (80%) | 48 (80%) |
| 40 | 55 (92%) | 55 (92%) |
| 50 | 59 (98%) | 59 (98%) |
| 65 | 60 (100%) | 60 (100%) |
| 75 | 60 (100%) | 60 (100%) |
| 85 | 44 (73%) | 44 (73%) |
Across all 364 studies, recruiting or not: 3% stop at 75 or younger and 1% at 65; 7% take children; <1% are for women only and 1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Carotid Stenosis studies take
Of 87 observational studies under Carotid Stenosis, half reached primary completion within 50 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo19–50 · 61 studies | — | 28 mo22–50 · 50 studies |
| Observational | 50 mo30–104 · 87 studies | — | 50 mo26–104 · 79 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting2
- Alirocumab for Stabilisation of Symptomatic Vulnerable Carotid PlaqueNov 12, 2026NCT07586540
- Evaluation of Balloon Guide Catheter as Proximal Protection During Carotid Artery Stenting (EMBO-PROTECT)Nov 10, 2026NCT07576790
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 364. Browse all 364 → or search them.
- Alirocumab for Stabilisation of Symptomatic Vulnerable Carotid PlaqueRecruitingNCT07586540Phase 38 countries
- Cerebral Oximetry During Awake Carotid EndarterectomyNot yet recruitingNCT078160811 country
- Evaluation of Balloon Guide Catheter as Proximal Protection During Carotid Artery Stenting (EMBO-PROTECT)RecruitingNCT07576790Not applicable1 country
- A Prospective, Multicenter, Single Arm Registry of ENROUTE NPS in Conjunction With Carotid WALLSTENT in Chinese PopulationNot yet recruitingNCT07458243
- Optical Coherence Tomography-Assisted Strategy for Interventional Management of Symptomatic Carotid Stenosis (OASIS-C)Not yet recruitingNCT07886775Not applicable1 country
- A First-in-Human Feasibility Study of the Vibrant Stroke Detection Technology During Carotid EndarterectomiesNot yet recruitingNCT078513891 country
- Perioperative GFAP and Neurological Complications After Carotid EndarterectomyRecruitingNCT078439791 country
- CEST-PROTECT: Proximal Flow Control With a Balloon Guide Catheter Plus Distal Embolic Protection: a Randomised, Open-label Trial Evaluating Cerebral Protection TechniquesNot yet recruitingNCT07841132Not applicable1 country
- Safety and Efficacy of Carotid Artery Stenting Combined With Intermittent Hypoxia Intervention in Patients With Severe Internal Carotid Artery StenosisNot yet recruitingNCT07837011Not applicable1 country
- Effects of Rosa Roxburghii Tratt Freeze-Dried Powder on Carotid Atherosclerotic Plaques: A Real-World StudyNot yet recruitingNCT07840950Not applicable
- Determination of the Best Therapeutic Strategy, Interventional With Best Medical Management (BMM) Versus BMM Alone, for Patients With Symptomatic Moderate <70% Atherosclerotic Carotid Artery Stenosis: the SIMCA Multicenter Randomized TrialNot yet recruitingNCT07839390Not applicable
- RESCUE: PCSK9 Inhibitors for Carotid Vulnerable Plaque RemodelingNot yet recruitingNCT07819643Phase 4
- Balloon Guide Catheter Combined With Filter Protection for Carotid Artery StentingRecruitingNCT07247864Not applicable1 country
- Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery StenosisRecruitingNCT077626641 country
- Endovascular Acute Stroke Intervention - Tandem OCclusion TrialRecruitingNCT04261478Not applicable1 country
- Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular StrokeRecruitingNCT077567751 country
- A Cohort Study Comparing PCSK9 Inhibitor Plus Statin With Statin Monotherapy for Carotid Artery StenosisRecruitingNCT070369911 country
- Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular DiseaseNot yet recruitingNCT07704190Phase 4
- Multicentric Study on Clopidogrel Resistance in DAPT for CAS (MULTI-RESCLOSA)RecruitingNCT055663011 country
- A Randomized Trial of Carotid Artery Stenting With Balloon Guide CatheterNot yet recruitingNCT07678164Not applicable
- Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid SurgeryRecruitingNCT07200180Phase 31 country
- CAROTID ENDATORECTOMY AND GENERAL ANESTHESIA: Assessment and Evaluation of Cerebral Ischemic Damage With Clinical, Laboratory and Imaging ParametersNot yet recruitingNCT07602400
- Whole-life Investigation of Lishui LongevityRecruitingNCT075929621 country
- Clinical Impact of Using IMPROVE to Select Patients for Carotid RevascularisationRecruitingNCT07556887Not applicable1 country
- Prospective Carotid Artery Stenosis TrialRecruitingNCT057248361 country
- Oral Microbiome in Carotid AtherosclerosisRecruitingNCT072969651 country
- CAS for Stenosis With High-risk Features for CEARecruitingNCT07370246Not applicable1 country
- Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery StenosisRecruitingNCT07412249Not applicable1 country
- Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-controlRecruitingNCT02748941Not applicable1 country
- 18F FDG and 68Ga FAPI PET/MR Imaging of Carotid Artery Plaque Vulnerability: A Clinical Study in Carotid Artery Plaque PatientsRecruitingNCT070046731 country
- High Coverage CARotid Stenting vs. Medical Management Alone to Prevent EmboliSm From symptomaTic Non-stenotic cARotid Disease (SyNC)RecruitingNCT071667311 country
- Asymptomatic Carotid Stenosis and Mobility Function With Exercise InterventionRecruitingNCT05436600Not applicable1 country
- CGUARDIANS III IDE Pivotal TrialNot yet recruitingNCT07277296Not applicable
- Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep LearningRecruitingNCT058008211 country
- NON CANONICAL ACTIVATION OF BOOD COAGULATIONNot yet recruitingNCT07242521
- Research on Ultrasound Diagnostic Criteria for Intracranial and Extracranial Arterial Serial StenosisNot yet recruitingNCT069477201 country
- [18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery DiseaseRecruitingNCT07104487Phase 21 country
- Study on the Trans-Carotid Artery Occlusion Shunt SystemRecruitingNCT06924593Not applicable1 country
- Improved Medication and Care to Achieve Lipid Targets After Carotid SurgeryNot yet recruitingNCT07064135Not applicable1 country
- Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking StudyRecruitingNCT070572971 country
- A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery StenosisRecruitingNCT070341571 country
- A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization ApproachRecruitingNCT06653387Not applicable1 country
- Study of Human Ocular Hemodynamics by Holography DoppleNot yet recruitingNCT06989996Not applicable
- Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)(Extended Follow-Up)RecruitingNCT069361891 country
- Prospective Trial of IVL for Calcified Carotid Lesions(CREATE Trial)RecruitingNCT06936176Not applicable1 country
- Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer SetsRecruitingNCT06959628Not applicable1 country
- Study on PAD and CAS Based on Omics and ImagingNot yet recruitingNCT06917547
- Predictive Value of Neovascularization Within Asymptomatic Carotis Stenosis on CEUSRecruitingNCT017325231 country
- Monitoring of Brain Metabolites Using Proton and Deuterium MR TechniquesNot yet recruitingNCT06705010Not applicable1 country
- The Management of Asymptomatic Carotid StenosisRecruitingNCT068829541 country