Carotid Artery Diseases clinical trials
The registry lists 259 studies for Carotid Artery Diseases across more than 10 countries. 60 are recruiting or about to start. 123 of them are mainly about Carotid Artery Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 2 narrower conditions too, such as Carotid Stenosis: 620 studies, 153 open.
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Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (11) · Silk Road Medical (8) · Abbott Medical Devices (8) · Columbia University (7) · Assistance Publique - Hôpitaux de Paris (5) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (5) · Boston Scientific Corporation (4) · Washington University School of Medicine (4)
What is being tested here
Drugs under test in Carotid Artery Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Aspirin | 2 | 0 | 2 |
| Pegulicianine | 1 | 0 | 1 |
| Menaquinone 7 | 1 | 0 | 1 |
| Cholecalciferol | 1 | 0 | 1 |
| Niacin | 0 | 0 | 3 |
| Simvastatin | 0 | 0 | 2 |
| Atorvastatin | 0 | 0 | 2 |
| Rimonabant | 0 | 1 | 2 |
| Interleukin-2 | 0 | 0 | 1 |
| Dapagliflozin | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach · InspireMD
- Dec 2026The CREST-2 Registry · University of Maryland, Baltimore
- Dec 2026Carotid Atherosclerosis in Predicting Coronary Artery Disease · Shanghai Zhongshan Hospital
- Dec 2026SVS VQI TransCarotid Revascularization Surveillance Project · Society for Vascular Surgery Patient Safety Organization
- Feb 2027Randomized Controlled Trial on Carotid Atherosclerosis Screening in Asymptomatic Smokers and Hypertensive Adults: Prevalence and Impact on Cardiovascular Prevention · Universidade do Porto
- May 2027Endovascular Acute Stroke Intervention - Tandem OCclusion Trial · Centre hospitalier de l'Université de Montréal (CHUM)
- May 2027Implementation of an Algorithm- and Multi-professional Team-supported Strategy to Improve Lipid Management of Patients With Atherosclerotic Cardiovascular Disease · Colorado Prevention Center
- May 2027PET-MR Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Multisite) · Washington University School of Medicine
- May 2027CANF-Comb-II PET-MR in Atherosclerosis Multisite · Washington University School of Medicine
- Jun 2027Evaluate the Precision of ABL-101 Perfluorocarbon and Fluorine-19 MRI for the Mapping of Atherosclerotic Plaque Composition and Inflammation in Patients Undergoing Carotid Endarterectomy · Ruud van Heeswijk
Who these studies take
Of the 47 Carotid Artery Diseases studies recruiting now, 32 (68%) set no upper age limit and 2 (4%) stop at 75 or younger. 3 (6%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 3 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (2%) | 1 (2%) |
| 18 | 39 (83%) | 38 (81%) |
| 30 | 42 (89%) | 41 (87%) |
| 40 | 43 (91%) | 42 (89%) |
| 50 | 46 (98%) | 45 (96%) |
| 65 | 47 (100%) | 46 (98%) |
| 75 | 45 (96%) | 44 (94%) |
| 85 | 38 (81%) | 37 (79%) |
Across all 259 studies, recruiting or not: 12% stop at 75 or younger and 4% at 65; 13% take children; 2% are for women only and 3% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Carotid Artery Diseases studies take
Of 45 observational studies under Carotid Artery Diseases, half reached primary completion within 45 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 32 mo20–59 · 42 studies | — | — |
| Observational | 45 mo36–94 · 45 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 259. Browse all 259 → or search them.
- Cerebral Oximetry During Awake Carotid EndarterectomyNot yet recruitingNCT078160811 country
- PET-MR Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Multisite)Not yet recruitingNCT079168831 country
- Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)RecruitingNCT07611747Phase 41 country
- Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery PlaquesNot yet recruitingNCT06957821Early Phase 11 country
- Real-World Treatment of Extracranial Carotid Artery Disease With the ENROUTE™ Transcarotid Neuroprotection SystemRecruitingNCT074557471 country
- Predicting High-Risk Carotid Plaque: Integrating radioMics and biomEchanicsRecruitingNCT07877480Not applicable1 country
- Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)RecruitingNCT07062471Not applicable1 country
- Effects of Rosa Roxburghii Tratt Freeze-Dried Powder on Carotid Atherosclerotic Plaques: A Real-World StudyNot yet recruitingNCT07840950Not applicable
- The Role Oral Microbiome in the Development and Progression of Aorta Aneurysm and Carotid AtherosclerosisEnrolling by invitationNCT078249211 country
- Intervascular Post-Market Clinical Follow-Up (PMCF) RegistryRecruitingNCT073229134 countries
- Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery StenosisRecruitingNCT077626641 country
- Endovascular Acute Stroke Intervention - Tandem OCclusion TrialRecruitingNCT04261478Not applicable1 country
- Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Femoral Stenting (SKYWARD Trans-Femoral IDE [Investigational Device Exemption] Study)Not yet recruitingNCT07512128Not applicable1 country
- Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk PatientsRecruitingNCT06276374Not applicable1 country
- Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid SurgeryRecruitingNCT07200180Phase 31 country
- SNRK & Vascular Endothelial AgingRecruitingNCT075913371 country
- Clinical Impact of Using IMPROVE to Select Patients for Carotid RevascularisationRecruitingNCT07556887Not applicable1 country
- The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in WomenRecruitingNCT072840821 country
- Oral Microbiome in Carotid AtherosclerosisRecruitingNCT072969651 country
- 3D Contrast Enhanced Microvascular Ultrasound of Carotid Atherosclerosis for the Detection of Carotid Plaque Neo-Revascularisation.RecruitingNCT07298655Not applicable1 country
- CANF-Comb-II PET-MR in Atherosclerosis MultisiteRecruitingNCT058385471 country
- High Coverage CARotid Stenting vs. Medical Management Alone to Prevent EmboliSm From symptomaTic Non-stenotic cARotid Disease (SyNC)RecruitingNCT071667311 country
- The CREST-2 RegistryRecruitingNCT022408621 country
- Assessment of Platelet-derived GARP in Atherosclerotic DiseaseNot yet recruitingNCT073640581 country
- Implementation of an Algorithm- and Multi-professional Team-supported Strategy to Improve Lipid Management of Patients With Atherosclerotic Cardiovascular DiseaseRecruitingNCT07334834Not applicable1 country
- Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep LearningRecruitingNCT058008211 country
- Microflow3D - Non-invasive Mapping of Coronary Arteries and the Cerebral Vascular Network Using 3D Ultrasound Localization Microscopy in Patients With Atherosclerosis Prior to Carotid Endarterectomy SurgeryNot yet recruitingNCT07193225Not applicable1 country
- Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI)RecruitingNCT04046237Not applicable1 country
- [18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery DiseaseRecruitingNCT07104487Phase 21 country
- Study on the Trans-Carotid Artery Occlusion Shunt SystemRecruitingNCT06924593Not applicable1 country
- PET Detection of CCR2 in Human AtherosclerosisRecruitingNCT04537403Phase 11 country
- Residual Stenosis and Restenosis Following Carotid Endarterectomy With Primary Closure, A Prospective Tracking StudyRecruitingNCT070572971 country
- A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization ApproachRecruitingNCT06653387Not applicable1 country
- Hemodynamic Monitoring Carotid SurgeryRecruitingNCT06926010Not applicable1 country
- Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer SetsRecruitingNCT06959628Not applicable1 country
- Shear Wave Elastography for Carotid Atherosclerotic PlaquesRecruitingNCT062144291 country
- Efficacy and Safety Study of Endovascular Treatment of Asymptomatic Carotid Artery StenosisRecruitingNCT06899399Not applicable1 country
- Biomarkers and Unstable Carotid PlaqueRecruitingNCT068878941 country
- The Management of Asymptomatic Carotid StenosisRecruitingNCT068829541 country
- Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic DiseaseRecruitingNCT06541691Not applicable1 country
- Randomized Controlled Trial on Carotid Atherosclerosis Screening in Asymptomatic Smokers and Hypertensive Adults: Prevalence and Impact on Cardiovascular PreventionNot yet recruitingNCT06848283Not applicable
- Evaluate the Precision of ABL-101 Perfluorocarbon and Fluorine-19 MRI for the Mapping of Atherosclerotic Plaque Composition and Inflammation in Patients Undergoing Carotid EndarterectomyNot yet recruitingNCT06850324Phase 21 country
- Carotid Intraplaque Neovascularization Combined With Stress EchoRecruitingNCT054163851 country
- Assessing Neurocognition After Cerebrovascular InterventionRecruitingNCT03344276Not applicable1 country
- Cardiac Abnormalities in Stroke Prevention and Risk of RecurrenceEnrolling by invitationNCT063983661 country
- Stress Reduction Using Video Googles on Patients Undergoing Vascular SurgeryRecruitingNCT06704230Not applicable1 country
- The Role of Maintaining External Carotid Artery Flow in Graft Interposition After Carotid EndarterectomyRecruitingNCT065287171 country
- Carotid Artery Stenting During Endovascular Treatment of Acute StrokeRecruitingNCT06511089Phase 31 country
- Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air PollutionRecruitingNCT06261606Not applicable1 country
- Carotid Atherosclerosis in Predicting Coronary Artery DiseaseRecruitingNCT062539621 country