Bundle-Branch Block clinical trials
The registry lists 94 studies for Bundle-Branch Block across more than 10 countries. 30 are recruiting or about to start. 40 of them are mainly about Bundle-Branch Block (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
Get an email when these change. Save the Bundle-Branch Block studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Rigshospitalet, Denmark (3) · Boston Scientific Corporation (3) · Maastricht University Medical Center (3) · Medtronic Cardiac Rhythm and Heart Failure (3) · University Medical Centre Ljubljana (2) · University of Aarhus (2) · Duke University (2) · Tomsk National Research Medical Center of the Russian Academy of Sciences (2)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Dec 2026Clinical Efficacy and Safety of Left Bundle Branch Area Pacing Using Quantitative Guidance of Multimodal Data in the Treatment of Heart Failure · Second Affiliated Hospital of Nanchang University
- Dec 2026Prophylactic Permanent Pacemaker in Patients With Right Bundle Branch Block Undergoing Transcatheter Aortic Valve Implantation · Aalborg University Hospital
- Dec 2026Machine Learning for Diagnosis of Occlusive MI in LBBB Patients · Konya City Hospital
- May 2027Management of Patients With New Left Bundle Branch Block After Transcatheter Aortic Valve Implantation · Assistance Publique Hopitaux De Marseille
- Jul 2027His-Bundle Corrective Pacing in Heart Failure · University of Rochester
- Sep 2027Improving CRT Outcome With Non-Invasive Cardiac Mapping · EP Solutions SA
- Oct 2027LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB · The First Affiliated Hospital with Nanjing Medical University
Who these studies take
Of the 23 Bundle-Branch Block studies recruiting now, 14 (61%) set no upper age limit and 2 (9%) stop at 75 or younger. 2 (9%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (4%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (9%) | 2 (9%) |
| 18 | 23 (100%) | 23 (100%) |
| 30 | 23 (100%) | 23 (100%) |
| 40 | 23 (100%) | 23 (100%) |
| 50 | 23 (100%) | 23 (100%) |
| 65 | 22 (96%) | 22 (96%) |
| 75 | 22 (96%) | 22 (96%) |
| 85 | 18 (78%) | 18 (78%) |
Across all 94 studies, recruiting or not: 7% stop at 75 or younger and 4% at 65; 16% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Bundle-Branch Block studies take
Of 32 interventional studies with no phase under Bundle-Branch Block, half reached primary completion within 50 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 50 mo33–61 · 32 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Novel Approach to Conduction System Pacing With Use of UltrasoundOct 19, 2026NCT06815783
Newly registered1
- LBBAP Versus ILR in Patients With New-Onset LBBB and Moderately Reduced LVEF After TAVINov 2, 2026NCT07909239
Studies
Recruiting first, then most recently updated. Showing 50 of 94. Browse all 94 → or search them.
- LBBAP Versus ILR in Patients With New-Onset LBBB and Moderately Reduced LVEF After TAVINot yet recruitingNCT07909239Not applicable1 country
- Novel Approach to Conduction System Pacing With Use of UltrasoundRecruitingNCT06815783Not applicable1 country
- Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVIRecruitingNCT03303612Not applicable2 countries
- Clinical Efficacy and Safety of Left Bundle Branch Area Pacing Using Quantitative Guidance of Multimodal Data in the Treatment of Heart FailureRecruitingNCT07814612Not applicable1 country
- Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal CaptureNot yet recruitingNCT07804394Not applicable
- Left Bundle Branch Area Mapping for Conduction System PacingRecruitingNCT058843591 country
- REstoration of SYNChronous Cardiac Function Due to Physiologic cArdiac Pacing Modalities With Clinical EndpointsNot yet recruitingNCT076845471 country
- Cardiac Contractility Modulation in Chagas Heart DiseaseRecruitingNCT05519046Not applicable1 country
- Machine Learning for Diagnosis of Occlusive MI in LBBB PatientsRecruitingNCT076201191 country
- Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following TAVRRecruitingNCT041396161 country
- His-Bundle Corrective Pacing in Heart FailureRecruitingNCT05265520Not applicable1 country
- Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure PatientsRecruitingNCT05769036Not applicable1 country
- Improving CRT Outcome With Non-Invasive Cardiac MappingRecruitingNCT05564793Not applicable4 countries
- UHF ECG in LBBB and Response to CRT PredictionRecruitingNCT07057544Not applicable1 country
- Management of Patients With New Left Bundle Branch Block After Transcatheter Aortic Valve ImplantationRecruitingNCT06148883Not applicable1 country
- Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Block With Cardiac Resynchronization TherapyRecruitingNCT055646891 country
- EArly Effect of Glucocorticoid on Incidence of Persistent Left BundlE Branch Block (LBBB) Post-TAVR (EAGLE-TAVR Trial)Not yet recruitingNCT06762145Phase 41 country
- Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT NonrespondersRecruitingNCT05760924Not applicable1 country
- Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy AssessmentRecruitingNCT05327062Not applicable7 countries
- Pacing to Maintain Physiologic Ventricular ActivationRecruitingNCT044169581 country
- HIS Alternative II - UK SiteRecruitingNCT05814263Not applicable1 country
- ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System PacingRecruitingNCT063246821 country
- A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection SoftwareEnrolling by invitationNCT059033131 country
- Outcomes and Safety of Various Conduction System Pacing MethodsRecruitingNCT047498361 country
- Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances (GLUCO-TAVR).RecruitingNCT06076824Phase 41 country
- Prophylactic Permanent Pacemaker in Patients With Right Bundle Branch Block Undergoing Transcatheter Aortic Valve ImplantationNot yet recruitingNCT05889208Not applicable
- Prediction of Outcome by Echocardiography in Left Bundle Branch BlockRecruitingNCT042934711 country
- Clinical Observational Registry of Patients With Left Bundle Branch BlockRecruitingNCT052836031 country
- Clinical, Structural and Mechanical Features in Patients With Left Bundle Branch Block.Not yet recruitingNCT04328649
- Prognosis of Patients With Compete Left Bundle Branch BlockRecruitingNCT030966781 country
- REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)Active, not recruitingNCT05652218Not applicable1 country
- Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-upActive, not recruitingNCT072098527 countries
- Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)CompletedNCT06601322Not applicable1 country
- DANISH-CRT - Does Electric Targeted LV Lead Positioning Improve Outcome in Patients With Heart Failure and Prolonged QRSCompletedNCT03280862Not applicable1 country
- A Multimodal Strategy to Screen for and Rule-Out Delayed High-Grade Conduction Disturbances After TAVRCompletedNCT074144851 country
- LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBBActive, not recruitingNCT05572957Not applicable1 country
- THE RELATIONSHIP BETWEEN CARDIAC RESYNCHRONİZATION THERAPY RESPONSE IN HEART FAILURE PATIENTS AND YKL-40 LEVELSActive, not recruitingNCT074691371 country
- Direct HIS/LBB Pacing as an Alternative to Biventricular Pacing in Patients With HFrEF and a Typical LBBB.CompletedNCT04409119Not applicable1 country
- Pain Relief and and Peripheral Perfusion Index During Erector Spinae BlockCompletedNCT06963424Not applicable1 country
- Mapping and Pacing of the His Bundle for Heart Failure Patients With Left Bundle Branch BlockCompletedNCT03803995Not applicable1 country
- The Left Bundle Cardiac Resynchronization Therapy TrialActive, not recruitingNCT05434962Not applicable1 country
- Study on Heart Block Risks Using Outcome-Based ModelingCompletedNCT07065123
- Mid-Q Response StudyCompletedNCT04180696Not applicable10 countries
- Conduction System Pacing Versus Biventricular Resynchronization in Patients With Chronic Heart FailureCompletedNCT05572736Not applicable1 country
- Optimised MultiSite Pacing Vector StudyWithdrawnNCT03938090Not applicable1 country
- Adaptive CRT Effect on Electrical DyssynchronyCompletedNCT02543281Not applicable1 country
- BIOTRONIK Conduction System Pacing With the Solia LeadCompletedNCT05251363Not applicable1 country
- Acute Hemodynamic Effects of Pacing the His Bundle in Heart FailureTerminatedNCT04701112Not applicable1 country
- LV Only MPP With SyncAVCompletedNCT03567096Not applicable4 countries
- Conduction System Pacing Versus Biventricular Pacing for Cardiac ResYNChronizationCompletedNCT05155865Not applicable1 country