Adenocarcinoma Of Esophagus: all 354 studies
Page 1 of 4. Open to participants first (81), then studies with results posted, then the rest; newest registration first within each.
- Lucid BE Biomarkers StudyNot yet recruitingNCT07887568
- A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in Participants With Gastric Cancer, Esophagogastric Junction Cancer, or Esophageal AdenocarcinomaNot yet recruitingNCT07818070Phase 3
- A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction AdenocarcinomaRecruitingNCT07818018Phase 1/2
- Breath Research Narrow Validation for Gastrointestinal Cancer DetectionRecruitingNCT07714538
- Clonal Hematopoiesis Chemotherapy and Radiation Effects StudyRecruitingNCT07675967
- Determining Minimal Residual Disease Using ctDNA Deep SequencingRecruitingNCT07660627Not applicable
- Dual-Target CLDN18.2/HER2 CAR-NK Cells for Advanced Esophageal AdenocarcinomaRecruitingNCT07622940Phase 1/2
- Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal AdenocarcinomaRecruitingNCT07603375Phase 2
- Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal AdenocarcinomaNot yet recruitingNCT07594548Phase 1
- A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal CancersRecruitingNCT07544589Phase 1
- Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)RecruitingNCT07432295Phase 2
- Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2RecruitingNCT07431281Phase 3
- Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal CancerRecruitingNCT07392892Phase 2/3
- Will a Pre-therapy Exercise Intervention Improve the Outcomes of Patients With Advanced Oesophageal Cancer?RecruitingNCT07375420Not applicable
- Combination of Chemotherapy and Adaptive MR-Guided Radiotherapy to Improve Outcomes in Patients With Esophageal AdenocarcinomaRecruitingNCT07359443Phase 1
- Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal DissectionRecruitingNCT07343869
- Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-304 in Adults With Advanced HER2-Expressing Solid TumorsRecruitingNCT07334119Phase 1
- Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical EsophagectomyRecruitingNCT07309991
- First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid TumorsRecruitingNCT07284186Phase 1
- Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) LevelsRecruitingNCT07282912Phase 2
- A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsRecruitingNCT07277413Phase 1
- AUGMENTED RESPONSE OF VOLATILE BIOMARKERS IN THE ASSESSMENT OF OESOPHAGOGASTRIC CANCER (AROMA2)Not yet recruitingNCT07260734
- Patient Preference for Subcutaneous vs. Intravenous Immune TherapyRecruitingNCT07223424Phase 2
- Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal AdenocarcinomaRecruitingNCT07222657Phase 2
- A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)RecruitingNCT07221149Phase 2/3
- Minimally Invasive Molecular Approaches for the Detection of Barrett's Esophagus- High Grade Dysplasia and Esophageal AdenocarcinomaEnrolling by invitationNCT07212491
- Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C TrialNot yet recruitingNCT07206589Not applicable
- A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid TumorsRecruitingNCT07182149Phase 1
- Low-Dose Radiotherapy in Patients With Advanced Esophageal Squamous Cell Carcinoma Resistant to First-Line Chemotherapy Combined With ImmunotherapyNot yet recruitingNCT07164690Phase 2
- Evaluation of Seismocardiography(SCG) for Assessing Fitness and Predicting Outcomes in Oesophageal Cancer SurgeryRecruitingNCT07159711
- Outcomes of a Single Chest Drain vs Two DrainsRecruitingNCT07125248Not applicable
- A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid TumorsRecruitingNCT07090499Phase 1
- Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal AdenocarcinomaNot yet recruitingNCT07059611Phase 2
- A Phase Ib Trial Evaluating the Safety and Activity of Neoadjuvant Combination of Tislelizumab Plus FLOT for Resectable Esophagogastric AdenocarcinomaRecruitingNCT07059299Phase 1
- Evaluation of Efficacy and Safety De-escalation Versus Standard Adjuvant Chemotherapy in Patients With Low Risk Localized Gastroesophageal AdenocarcinomaNot yet recruitingNCT06933966Phase 2
- Testing Ivonescimab in Combination With Chemotherapy in Advanced or Metastatic Gastric/Gastroesophageal AdenocarcinomaRecruitingNCT06846346Phase 2
- ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a MuRecruitingNCT06824363Early Phase 1
- Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's EsophagusRecruitingNCT06732388Phase 2
- Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant ChemoradiotherapyRecruitingNCT06687876Phase 2
- Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD SymptomsRecruitingNCT06687603Not applicable
- A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid TumorsRecruitingNCT06657144Phase 1
- A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer or Malignant Peritoneal MesotheliomaRecruitingNCT06623396Phase 1
- Barrett's Esophagitis in Anorexia Nervosa Binge/Purge SubtypeRecruitingNCT06532734
- A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of CancerRecruitingNCT06523374Not applicable
- Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric AdenocarcinomaRecruitingNCT06340711Phase 2
- A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)RecruitingNCT06330064Phase 1/2
- Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has SpreadRecruitingNCT06324357Phase 1/2
- Longitudinal Assessment of Biomarkers After Oesophagogastric Cancer SurgeryRecruitingNCT06289374
- Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE TrialRecruitingNCT06203600Phase 2/3
- Total Neoadjuvant Therapy for Lymph Node-positive Adenocarcinoma of the OESophagus and Oesophagogastric JunctionRecruitingNCT06161818Phase 2
- Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal SamplesRecruitingNCT06071845Not applicable
- Oral TGF-beta Receptor I Inhibitor Vactosertib in SOC Chemoradiotherapy for Esophageal AdenocarcinomaRecruitingNCT06044311Phase 2
- Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid TumorsRecruitingNCT06005493Phase 1/2
- Lucid Registry StudyRecruitingNCT05965999
- A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid TumorsRecruitingNCT05954312Phase 1
- Chemotherapy in the Context of Esophageal and Gastroesophageal Junction Cancer CachexiaNot yet recruitingNCT05954117Not applicable
- Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade DysplasiaRecruitingNCT05753748Not applicable
- Oral Bevacizumab-800CW and Cetuximab-800CW Administration to Detect Early Esophageal AdenocarcinomasRecruitingNCT05745857Phase 2
- mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric AdenocarcinomaRecruitingNCT05677490Phase 3
- Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction AdenocarcinomaRecruitingNCT05651594Phase 2
- A Multicenter Prospective Cohort Study Comparing Random Biopsies Versus Wide-Area Transepithelial Brush-Sampling (WATS) for Surveillance of Barrett's Esophagus, the WATS-EURO2 StudyRecruitingNCT05642338
- Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in HumansRecruitingNCT05591053Not applicable
- A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal CancerRecruitingNCT05563766Phase 2
- Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing SurveillanceRecruitingNCT05530343Not applicable
- Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo MeasurementsRecruitingNCT05247346Not applicable
- TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal CancerRecruitingNCT05188313Phase 3
- Anti-PD-1 and CapOx for the First-line Treatment of dMMR Esophagogastric Cancer (AuspiCiOus)RecruitingNCT05177133Phase 2
- Obeticholic Acid for Prevention in Barrett's EsophagusRecruitingNCT04939051Phase 2
- Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid TumorsRecruitingNCT04900818Phase 1
- Propranolol With Chemotherapy or Chemoradiation for Esophageal AdenocarcinomaRecruitingNCT04682158Phase 2
- A Study of Sigvotatug Vedotin in Advanced Solid TumorsRecruitingNCT04389632Phase 1
- RAMIE Versus MIE for Resectable Esophageal Cancer, a Randomized Controlled Trial (ROBOT-2 Trial).RecruitingNCT04306458Not applicable
- Registry Platform Gastric/Esophageal Cancer (SAPHIR)RecruitingNCT04290806
- Radiation Therapy for the Treatment of Metastatic Gastrointestinal CancersRecruitingNCT04221893Not applicable
- Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric AdenocarcinomaRecruitingNCT04150640Phase 2
- Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor MalignanciesRecruitingNCT04114136Phase 2
- Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal CancerRecruitingNCT04018872Phase 2
- Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal MalignanciesRecruitingNCT03539822Phase 1/2
- Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric CancerRecruitingNCT03161522Phase 2
- The Effect of Ablation Therapy on Barrett's EsophagusEnrolling by invitationNCT00587314
- Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's RegistryRecruitingNCT00574327
- A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)CompletedNCT05104567Phase 2Results posted
- Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction CancerActive, not recruitingNCT04929392Phase 2Results posted
- Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction CaCompletedNCT04921904Phase 1/2Results posted
- Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract TumorsTerminatedNCT04683939Phase 1/2Results posted
- Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal CancerCompletedNCT04499924Phase 2/3Results posted
- Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction CancersActive, not recruitingNCT04460937Phase 1Results posted
- Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal CancersActive, not recruitingNCT04430738Phase 2Results posted
- Phase II Trial of Neoadjuvant Pembrolizumab for Patients With Early Stage Gastroesophageal AdenocarcinomaTerminatedNCT04089904Phase 2Results posted
- Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal AdenocarcinomasCompletedNCT03783936Phase 2Results posted
- M6620 Plus Standard Treatment in Oesophageal and Other CancerCompletedNCT03641547Phase 1Results posted
- Rapid Assessment of Esophageal Adenocarcinoma Risk TestTerminatedNCT03366012Not applicableResults posted
- PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic MalignanciesCompletedNCT03365791Phase 2Results posted
- Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision TherapyTerminatedNCT03223662Phase 2Results posted
- Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction or Esophageal CancersTerminatedNCT03122548Phase 2Results posted
- Study of Pembrolizumab in Locally Advanced Esophageal AdenocarcinomaActive, not recruitingNCT02998268Phase 2Results posted
- Pembrolizumab in Refractory Advanced Esophageal CancerCompletedNCT02971956Phase 2Results posted
- Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction CancerCompletedNCT02872116Phase 3Results posted
- Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction CancerCompletedNCT02830594Phase 2Results posted
- Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal CancerCompletedNCT02735239Phase 1/2Results posted