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RecruitingNCT07125248Updated Aug 15, 2025

Outcomes of a Single Chest Drain vs Two Drains

An interventional study of Bilateral chest tube placement and Single drain placement in Pleura; Effusion, Esophageal Adenocarcinoma and Esophageal Anastomotic Leak, sponsored by Khyber Teaching Hospital. Recruiting at 1 site in Pakistan. Per ClinicalTrials.gov, last updated 2025-08-15.

Sponsored by Khyber Teaching Hospital · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Primary completion was expected by Sep 2025, 1 year 2 months ago, but the record still lists the study as recruiting.
  • Registered 5 months after the study started (first participant enrolled Feb 2025, registered Aug 2025).
  • Started Feb 2025; still recruiting 1 year 8 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
68
Allocation
Randomized
Sex
All
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Study summary

Esophagectomy is a major surgical procedure done for carcinoma of esophagus. Usually bilateral chest tubes are placed in surgery for prevention of fluid accumulation in chest. However such procedure limits patients mobility and increases severity of pain. recent studies suggest that a single drain can be safe and effective. our study aims to compare the results of two chest tubes vs one.

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Conditions studied

  • Pleura; Effusion
  • Esophageal Adenocarcinoma
  • Esophageal Anastomotic Leak
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In context

Pleural Effusion

241 studies on the registry are indexed under Pleural Effusion; 50 are open to participants now.

This study's planned enrollment of 68 is below the median of 80 across 142 interventional studies indexed under Pleural Effusion.

Browse Pleural Effusion studies →

Lead sponsor

Khyber Teaching Hospital is the lead sponsor of 29 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients undergoing open esophagectomy for carcinoma of esophagus

Exclusion criteria

Exclusion Criteria:

  • Non consenting individuals esophagectomy for benign disease
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Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
68 participants (estimated)

Study arms

  • Experimental
    Bilateral chest drains group

    Participants in this group will have bilateral intercostal chest tubes placed during surgery.

    Procedure: Bilateral chest tube placement

  • Experimental
    Single drain group

    Paricipants in this group will have a single transhiatal drain placed in mediastinum that would be brought out through abdomen

    Procedure: Single drain placement

Interventions

  • ProcedureBilateral chest tube placement

    Bilateral chest tubes will be passed in this intervention group through intercostal spaces

  • ProcedureSingle drain placement

    A single transhiatal drain will be placed in mediastinum in this group

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What researchers measure

Primary outcomes

  1. Chest expansion

    Chest expansion will be observed by chest xray postoperatively

    Time frame: On postoperative day 1 and day 3 .

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Study locations

1 of 1 sites recruiting
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References and documents

Individual participant data

Plan to share: No — Patients data will be confidential

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 15, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07125248
Lead sponsor
Khyber Teaching Hospital
Responsible party
Dr Saeed Sarwar (Doctor, Khyber Teaching Hospital) — Principal investigator
First posted
Aug 15, 2025
Start date
Feb 28, 2025
Primary completion
Sep 1, 2025 (estimated)
Completion
Sep 10, 2025 (estimated)
Last update
Aug 15, 2025

Study contacts

Saeed Sarwar, MBBS
Contact
saeedkmc2020@gmail.com
+923420973863

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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