National Institutes of Health: all 11,571 studies

Page 13 of 116. Open to participants first (946), then studies with results posted, then the rest; newest registration first within each.

• Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in PsoriasisCompletedNCT04271735Not applicableResults posted
• Treatment of Refractory Diamond-Blackfan Anemia With EltrombopagCompletedNCT04269889Phase 1/2Results posted
• Electromagnetic Tracking and Optical Imaging With ICG for Hepatic BiopsiesTerminatedNCT04258566Not applicableResults posted
• Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung CancerActive, not recruitingNCT04250545Phase 1Results posted
• Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus InfectionCompletedNCT04247282Phase 1/2Results posted
• Phase 2 Shigella Vaccine and ChallengeCompletedNCT04242264Phase 2Results posted
• Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine TumorsActive, not recruitingNCT04234568Phase 1Results posted
• Genomic Effects of Glucocorticoids in Patients With Systemic Lupus ErythematosusCompletedNCT04233164Early Phase 1Results posted
• Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)CompletedNCT04216589Phase 2Results posted
• Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed GlioblastomaActive, not recruitingNCT04216329Phase 1Results posted
• Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung CancerActive, not recruitingNCT04216316Phase 1/2Results posted
• Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung CancerActive, not recruitingNCT04214262Phase 3Results posted
• BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid LeukemiaActive, not recruitingNCT04214249Phase 2Results posted
• Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy, HIV-uninfected Adult ParticipantsCompletedNCT04212091Phase 1Results posted
• Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaTerminatedNCT04209621Phase 2Results posted
• PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell CancersCompletedNCT04209595Phase 1/2Results posted
• Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)CompletedNCT04209075Phase 2Results posted
• Safety and Pharmacokinetics of VT-1598CompletedNCT04208321Phase 1Results posted
• Trial to Evaluate CIS43LS in Healthy AdultsCompletedNCT04206332Phase 1Results posted
• Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR StudyActive, not recruitingNCT04197713Phase 1Results posted
• Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT04195555Phase 2Results posted
• B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-BCompletedNCT04193189Phase 3Results posted
• Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary SyndromeCompletedNCT04185220Phase 1Results posted
• Evaluating the Safety and Immunogenicity of HIV-1 BG505 SOSIP.664 gp140 With TLR Agonist and/or Alum Adjuvants in Healthy, HIV-uninfected AdultsCompletedNCT04177355Phase 1Results posted
• Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the LiverActive, not recruitingNCT04175912Phase 2Results posted
• Phase I Norovirus Challenge ModelCompletedNCT04174560Phase 1Results posted
• VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)TerminatedNCT04166383Phase 2Results posted
• T Cells Expressing Fully-human Anti-CD19 and Anti-CD20 Chimeric Antigen Receptors for Treating B-cell Malignancies and Hodgkin LymphomaTerminatedNCT04160195Phase 1Results posted
• Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal CarcinomaTerminatedNCT04150562Phase 2Results posted
• A Proof-of-Concept Trial on the Effect of Ketamine on FatigueCompletedNCT04141696Phase 1/2Results posted
• Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant PairsCompletedNCT04140266Phase 3Results posted
• Mepolizumab in Episodic Angioedema With EosinophiliaTerminatedNCT04128371Phase 2Results posted
• Safety and Pharmacokinetics of RezafunginTerminatedNCT04117607Phase 1Results posted
• Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast CancerTerminatedNCT04108858Phase 1/2Results posted
• Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine TumorsActive, not recruitingNCT04079712Phase 2Results posted
• Treg Modulation With CD28 and IL-6 Receptor AntagonistsCompletedNCT04066114Phase 1/2Results posted
• Safety and Pharmacokinetic Study of Tenofovir Alafenamide (TAF)/Elvitegravir (EVG) Administered RectallyCompletedNCT04047420Phase 1Results posted
• H1N1v Virus Challenge Study in Healthy SubjectsCompletedNCT04044352Phase 1Results posted
• Ebola Sudan Chimpanzee Adenovirus Vector Vaccine in Healthy AdultsCompletedNCT04041570Phase 1Results posted
• Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal CancerActive, not recruitingNCT04034927Phase 2Results posted
• Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal CarcinomatosisTerminatedNCT04034251Phase 2Results posted
• Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid TumorsCompletedNCT04034238Phase 1Results posted
• LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)TerminatedNCT04027946Phase 2Results posted
• Systems Analyses of the Immune Response to the Seasonal Influenza VaccineCompletedNCT04025580Phase 2Results posted
• Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisCompletedNCT04025554Phase 1/2Results posted
• Dosage-Escalation Study of the Safety and Immunogenicity of a Novel Rabies Vaccine ChAd155-RG vs. the Comparator RABAVERT Vaccine in Healthy Adult SubjectsCompletedNCT04019444Phase 1Results posted
• E7 TCR Cell Induction Immunotherapy for Stage II and Stage III HPV-Associated Oropharyngeal CancerTerminatedNCT04015336Phase 2Results posted
• Evaluating the Safety and Immunogenicity of AGS-v PLUS, a Universal Mosquito-Borne Disease and Mosquito Control VaccineCompletedNCT04009824Phase 1Results posted
• A Dose-Finding Study of AG-348 in Sickle Cell DiseaseCompletedNCT04000165Early Phase 1Results posted
• Modulating the Hippocampal and Striatal Memory Networks With rTMSCompletedNCT03994120Not applicableResults posted
• Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Malaria Transmission Season in Healthy African Adult Women of Childbearing Potential in MaliCompletedNCT03989102Phase 2Results posted
• A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With AztreonamCompletedNCT03978091Phase 1/2Results posted
• HLAB-002 of ANS-6637 for Alcohol Use DisorderTerminatedNCT03970109Phase 2Results posted
• Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in PregnancyCompletedNCT03965923Phase 3Results posted
• Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With ImmunotherapyActive, not recruitingNCT03965689Phase 2Results posted
• T-cells Expressing an Anti-SLAMF7 CAR for Treating Multiple MyelomaCompletedNCT03958656Phase 1Results posted
• PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) RadioligandTerminatedNCT03958630Phase 1Results posted
• Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) MutationActive, not recruitingNCT03953898Phase 2Results posted
• Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...CompletedNCT03952650Phase 1/2Results posted
• De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal CancerActive, not recruitingNCT03952585Phase 2/3Results posted
• Flublok or Fluzone With Advax-CpG55.2 or AF03CompletedNCT03945825Phase 1Results posted
• Testing the Addition of Ixazomib/Placebo to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM TrialCompletedNCT03941860Phase 3Results posted
• Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast CancerActive, not recruitingNCT03939897Phase 1Results posted
• Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial LesionsTerminatedNCT03937791Phase 2Results posted
• Sensory Afferents for Deep Pressure SensationCompletedNCT03937778Not applicableResults posted
• Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult ParticipantsCompletedNCT03934541Phase 1Results posted
• Suppression Of Bacterial Vaginosis (BV) [SUBVert]CompletedNCT03930745Phase 2Results posted
• NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility StudyCompletedNCT03929913Not applicableResults posted
• Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult ParticipantsCompletedNCT03928821Phase 1Results posted
• Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in MaliCompletedNCT03917654Phase 2Results posted
• Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of AgeTerminatedNCT03916185Phase 1/2Results posted
• Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial CancerActive, not recruitingNCT03914612Phase 3Results posted
• Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid CancerActive, not recruitingNCT03914300Phase 2Results posted
• Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal ConditionsTerminatedNCT03912428Phase 1Results posted
• Intravenous Fosfomycin Pharmacokinetics StudyCompletedNCT03910673Phase 1Results posted
• Dried Blood Spot Testing of CMV Detection in HCT RecipientsCompletedNCT03910478Not applicableResults posted
• Avelumab in Combination With Hypofractionated Radiotherapy in Patients With Relapsed Refractory Multiple MyelomaTerminatedNCT03910439Phase 2Results posted
• Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin LymphomaActive, not recruitingNCT03907488Phase 3Results posted
• Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell MalignanciesCompletedNCT03905135Phase 1Results posted
• Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal FunctionCompletedNCT03896750Phase 1Results posted
• Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use DisorderCompletedNCT03896516Phase 1/2Results posted
• Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the LungsActive, not recruitingNCT03896503Phase 2Results posted
• A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and RifabutinCompletedNCT03891901Phase 2Results posted
• Combined Intrathecal and Intravenous VTS-270 Therapy for Liver and Neurological Disease Associated With Niemann-Pick Disease, Type C1TerminatedNCT03887533Phase 1/2Results posted
• StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With TuberculosisCompletedNCT03882177Phase 2Results posted
• Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic ParticipantsCompletedNCT03881696Phase 3Results posted
• A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine LeiomyosarcomaActive, not recruitingNCT03880019Phase 2Results posted
• VRC 313: A Trivalent Virus-like Particle (VLP) Encephalitis Vaccine (WEVEE) in Healthy AdultsCompletedNCT03879603Phase 1Results posted
• Intranasal Oxytocin for the Treatment of Alcohol Use DisorderCompletedNCT03878316Phase 2Results posted
• Translational Development of Photon-counting CT ImagingCompletedNCT03878134Not applicableResults posted
• Effects of Low Fat Versus Low Carbohydrate Diets on Energy MetabolismCompletedNCT03878108Not applicableResults posted
• Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant TumorsActive, not recruitingNCT03878095Phase 2Results posted
• Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN StudyActive, not recruitingNCT03872427Phase 2Results posted
• Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health VolunteersCompletedNCT03864406Phase 1Results posted
• Online Survey in Studying Smoking Attitudes and Behaviors Among Current SmokersCompletedNCT03863795Results posted
• Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D)CompletedNCT03861000Phase 1/2Results posted
• A Clinical Trial in Healthy, HIV-1-Uninfected Adult Participants to Compare the Safety, Tolerability and Immunogenicity of CH505TF gp120 Produced From Stably Transfected Cells to CH505TF gp120 Produced From Transiently Transfected CellsCompletedNCT03856996Phase 1Results posted
• Sodium-glucose Co Transporter 2 (sGLT2) Inhibitor and Endogenous Ketone ProductionCompletedNCT03852901Phase 1Results posted
• Clinical Study of a Diagnostic Device for NG, TV and CT in WomenCompletedNCT03852316Not applicableResults posted
• Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected MutationsActive, not recruitingNCT03842228Phase 1Results posted

← National Institutes of Health overview and focus areas