National Institutes of Health: all 11,571 studies

Page 1 of 116. Open to participants first (947), then studies with results posted, then the rest; newest registration first within each.

• Mirdametinib to Reduce the Size of Large/Giant Congenital Melanocytic Nevi in Children, Adolescents and Young AdultsNot yet recruitingNCT07891286Phase 2
• A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African WomenNot yet recruitingNCT07884240Phase 3
• Epcoritamab as Consolidative Therapy for Waldenstr(SqrRoot)(Delta)m Macroglobulinemia (WM) Treated With a Bruton Tyrosine Kinase Inhibitor (BTKi)Not yet recruitingNCT07882173Phase 2
• Metabolic Impact of VLCPUFA-Rich Fish Oil: A Clinical Study on Omega-3 Index Enhancement in Healthy IndividualsRecruitingNCT07882160Not applicable
• A Clinical Study of Ixazomib to Reactivate HIV and Reduce HIV Reservoir SizeNot yet recruitingNCT07881809Phase 2
• Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research UseNot yet recruitingNCT07877259
• A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric IllnessRecruitingNCT07877246
• Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES)Enrolling by invitationNCT07867184
• Testing the Investigational Medication Combination of Azacitidine, Venetoclax, and Quizartinib Compared to the Usual Treatment of Cytarabine, Daunorubicin, and Quizartinib for Patients With FLT3-ITD Mutant Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)Not yet recruitingNCT07862517Phase 2
• Positron Emission Tomography and Organ-Specific Changes in Participants Co-Enrolled in NIH Studies of Plasmodium Vivax Controlled Human Malaria InfectionNot yet recruitingNCT07859800Not applicable
• First-in-Human Evaluation of [11C]JMJ-129-d2 for PDE4D Imaging in Healthy VolunteersRecruitingNCT07853781Phase 1
• Pain Phenotyping of Rheumatic Diseases - An Observational StudyNot yet recruitingNCT07829497
• A Clinical Study of the HCMV-TB Vaccine Candidate VIR-1778 in Healthy AdultsNot yet recruitingNCT07818824Phase 1
• NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label DevicesNot yet recruitingNCT07806149Not applicable
• A Clinical Study to Evaluate the Safety and Immunogenicity of a Higher Dose of the Study Vaccine, VIR-1388, in HCMV-seropositive Adult Participants Without HIVNot yet recruitingNCT07801456Phase 1
• Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology ContinuumNot yet recruitingNCT07801079
• Noninvasive Neuromodulation Of The Subjective Value Network In Chronic PainNot yet recruitingNCT07798908Phase 1
• Nemtabrutinib for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Leukemia (SLL) Refractory to Covalent Bruton Tyrosine Kinase Inhibitor or Pirtobrutinib and Previously Treated With a BCL2 InhibitorNot yet recruitingNCT07796373Phase 2
• Dynamic Magnetic Resonance Imaging of Human Subarachnoid Space Using Intrathecal Gadolinium ContrastNot yet recruitingNCT07796360Phase 1
• Expanding HOPE LiverRecruitingNCT07778459
• Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIMEnrolling by invitationNCT07775313Phase 1/2
• Miniature In-line RespiratorNot yet recruitingNCT07768215Not applicable
• Augmenting Parent Management Training for Child Temper Outbursts Using a Digital ToolRecruitingNCT07764536
• Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy AdultsRecruitingNCT07757802Phase 1
• Visual Attention, Object Recognition, and Eye Movements in Healthy VolunteersRecruitingNCT07756853
• Combination Bevacizumab and PRGN-2012 in Adults With Recurrent Respiratory Papillomatosis (RRP)Not yet recruitingNCT07756840Phase 2
• Survey to Determine Incarcerated Persons' Views on Surrogate Decision MakingRecruitingNCT07751731
• Immune Dysregulation During Sepsis: A Natural History CohortNot yet recruitingNCT07735741
• Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit LymphomaNot yet recruitingNCT07724457Phase 2/3
• Neuroplasticity Enhancement From Cognitive Training Reinforced by PsilocybinRecruitingNCT07721467Phase 2
• Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump TherapyNot yet recruitingNCT07715903Phase 1
• Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic HyperlipidemiaNot yet recruitingNCT07715890Not applicable
• Screening ProtocolNot yet recruitingNCT07712874
• Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus InfectionRecruitingNCT07706686Phase 1
• ESCUDDO Long Term Follow UpEnrolling by invitationNCT07706673Phase 4
• Assessment of [18F]-Fluorocellobiose ([18F]FCB) Pharmacokinetics in Healthy Volunteers and Subjects With Invasive Mold InfectionsRecruitingNCT07704333Phase 1
• Safety and Immunogenicity of Chimeric Hemagglutinin mRNA Vaccine CandidatesNot yet recruitingNCT07703514Phase 1
• A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 VaccineNot yet recruitingNCT07703475Phase 1
• Healthy Volunteer Recruitment and Characterization for NINDS StudiesNot yet recruitingNCT07700511
• Testing the Investigational Medication Pembrolizumab After Kidney Removal for Patients With Non-Clear Cell Renal Cell CarcinomaNot yet recruitingNCT07689240Phase 3
• PET Imaging of Noradrenergic Transmission in the BrainRecruitingNCT07686393Phase 1
• IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation TherapyRecruitingNCT07686380Phase 2
• Testing the Anti-Cancer Drug, Brenetafusp (IMCF106C), in Rare CancersNot yet recruitingNCT07686367Phase 2
• Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related DisordersRecruitingNCT07683104
• Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs PlaceboNot yet recruitingNCT07683026Phase 2
• IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory Solid TumorsRecruitingNCT07672483Phase 1
• Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate CancerRecruitingNCT07667400Phase 1/2
• Ketoconazole Effects on the Daily Cortisol Rhythm in Mild Autonomous Cortisol SecretionRecruitingNCT07649317Phase 1
• AMC 120, Glofitamab Plus Chemoimmunotherapy in Newly Diagnosed HIV-Associated Large B-Cell Lymphoma (The "Glofit-RCHOP Study")Not yet recruitingNCT07649304Phase 1
• A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides DifficileNot yet recruitingNCT07649096Phase 1
• Pulmonary Hypertension (PH) Biorepository for Translational ResearchRecruitingNCT07647549
• Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive PsychotherapyRecruitingNCT07640802
• Olfactory Function and Model-Based Behavior in People Living With HIV and SUDRecruitingNCT07637669
• Discovering Determinants of Food Intake by Application of Artificial Intelligence to Complex, High-Dimensional DataNot yet recruitingNCT07637656
• Evaluation of [11C]ZTP-1 to Image PDE4BRecruitingNCT07625345Phase 1
• Longitudinal Immunophenotyping of Patients With Inflammatory Bowel DiseaseRecruitingNCT07619547
• Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain MetastasesRecruitingNCT07619534
• Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a (Trastuzumab Deruxtecan), for Advanced Pancreatic Ductal AdenocarcinomaRecruitingNCT07619521Phase 1/2
• Longitudinal Natural History Protocol for PRKN- and PINK1-Linked PDNot yet recruitingNCT07613112
• Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT ImagingRecruitingNCT07613099Phase 3
• Beginning to Assess an Appropriate CONtrol for Oral Food Challenges in Alpha-Gal Syndrome (CoFAR-13) - BeACON4AGRecruitingNCT07611435Phase 2
• Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM TrialRecruitingNCT07605416Phase 2
• Partial Stem Cell Transplant for Sickle Cell Disease From Matched DonorsRecruitingNCT07599176Phase 1/2
• A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingNCT07595042Phase 2
• Multitargeted Recombinant Ad5 PSA/MUC-1/Brachyury-Based Immunotherapy (TriAdeno) Vaccine With IL-15 Superagonist N-803 in Participants With Clinically Localized Prostate Cancer Undergoing Active SurveillanceNot yet recruitingNCT07574541Phase 2
• Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)RecruitingNCT07572136Phase 1
• Evaluating the Addition of Maintenance Immunotherapy Compared to the Usual Treatment of Chemotherapy and Autologous Stem Cell Transplant Alone for High-risk Patients With Relapsed or Refractory Hodgkin LymphomaNot yet recruitingNCT07572123Phase 2/3
• A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan AntibodiesRecruitingNCT07569029Phase 1
• Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell DiseaseRecruitingNCT07566494Phase 1
• Stress, Coping, and Sleep Health StudyNot yet recruitingNCT07566481
• Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)RecruitingNCT07566468
• Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)RecruitingNCT07559500Phase 1
• Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat TrialRecruitingNCT07551596Phase 2
• Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment and in the CirculationRecruitingNCT07549503Phase 2
• Human Experimental Models of Pain (HEMP)Not yet recruitingNCT07549490Not applicable
• Safety and Efficacy of PTH-IARecruitingNCT07541209Phase 1/2
• A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated AdultsRecruitingNCT07536308Phase 1
• Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood CancersNot yet recruitingNCT07524530Phase 2
• GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung TransplantationRecruitingNCT07516379
• Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT TrialRecruitingNCT07516366Phase 2
• Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot StudyRecruitingNCT07511049Phase 2
• Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory DiseaseRecruitingNCT07509034Phase 1
• Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy VolunteersNot yet recruitingNCT07504601Phase 2
• Sacituzumab Govitecan With Bevacizumab Compared to Usual Chemotherapy (Carboplatin, Pegylated Liposomal Doxorubicin and Bevacizumab) for Treating Recurrent Platinum-Sensitive Ovarian Cancer After PARP Inhibitor Maintenance TherapyRecruitingNCT07504588Phase 2
• Turner Syndrome: Genetic ConsiderationsRecruitingNCT07502586
• Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse EventEnrolling by invitationNCT07499128Not applicable
• NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid TumorsRecruitingNCT07489378
• Trial of Tirzepatide for the Treatment of Cannabis Use DisorderNot yet recruitingNCT07468552Phase 2
• A Trial Comparing Three Different Treatment Options for Adults With Low-Risk Myelodysplasia and Anemia (A MyeloMATCH Treatment Trial)Not yet recruitingNCT07463820Phase 2
• Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After TreatmentRecruitingNCT07463807Phase 1/2
• LYmph Node eXamination in Cat Allergen ImmunotherapyRecruitingNCT07447869Early Phase 1
• Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid TumorsRecruitingNCT07444723Phase 2/3
• Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) for Previously Untreated Mantle Cell LymphomaNot yet recruitingNCT07444710Phase 1
• A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With ObesityNot yet recruitingNCT07437976
• Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten WorseRecruitingNCT07437963Phase 1/2
• Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)RecruitingNCT07437950Phase 2
• Immune Profiling of CLL/SLL Treated With First-Line PirtobrutinibRecruitingNCT07428707Early Phase 1
• Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent GlioblastomaNot yet recruitingNCT07422363Phase 1
• Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without ThymectomyRecruitingNCT07416201
• Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent GlioblastomaRecruitingNCT07416188Phase 1/2

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