Tyrosine Kinase Inhibitors: all 10,469 studies that test it

Page 40 of 105. Open to participants first (1,907), then studies with results posted, then the rest; newest registration first within each.

• Sunitinib Malate in Treating Patients With Recurrent Transitional Cell Bladder CancerTerminatedNCT01118351Phase 2Results posted
• Extension to QTI571A2301 to Evaluate the Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)TerminatedNCT01117987Phase 3Results posted
• Continuous Dosing of BAY73-4506 in Patients With Advanced MalignanciesCompletedNCT01117623Phase 1Results posted
• Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast CancerActive, not recruitingNCT01116648Phase 1/2Results posted
• Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast CancerCompletedNCT01111825Phase 1/2Results posted
• Study of Lenvatinib in Subjects With Advanced Endometrial Cancer and Disease ProgressionCompletedNCT01111461Phase 2Results posted
• Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)TerminatedNCT01110876Phase 1/2Results posted
• Safety and Tolerability Study of PCI-32765 in B Cell Lymphoma and Chronic Lymphocytic LeukemiaCompletedNCT01109069Phase 2Results posted
• A Phase 2 Study of Pertuzumab and Erlotinib for Refractory Pancreatic AdenocarcinomaTerminatedNCT01108458Phase 2Results posted
• Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell CarcinomaCompletedNCT01108445Phase 2Results posted
• Phase II Pazopanib in Combination With Weekly Paclitaxel in Refractory Urothelial CancerCompletedNCT01108055Phase 2Results posted
• Pazopanib and Paclitaxel as First-Line Treatment for Subjects With Unresectable Stage III and Stage IV MelanomaCompletedNCT01107665Phase 2Results posted
• A Dose Finding Study Of A New Medication, PF-00337210 That Will Possibly Decrease Blood Supply To TumorsCompletedNCT01105533Phase 1Results posted
• Safety of PCI-32765 in Chronic Lymphocytic LeukemiaCompletedNCT01105247Phase 1/2Results posted
• Eribulin Mesylate in Combination With Intermittent Erlotinib in Patients With Previously Treated, Advanced Non-Small Cell Lung CancerCompletedNCT01104155Phase 2Results posted
• Patients With Metastatic Colorectal Cancer Treated With Regorafenib or Placebo After Failure of Standard TherapyCompletedNCT01103323Phase 3Results posted
• Velcade and Sorafenib in Unresected or Metastatic Renal Cell CarcinomaTerminatedNCT01100242Phase 2Results posted
• Effects of cKit Inhibition by Imatinib in Patients With Severe Refractory Asthma (KIA)CompletedNCT01097694Phase 2Results posted
• Sorafenib Tosylate and Erlotinib Hydrochloride in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gallbladder Cancer or CholangiocarcinomaCompletedNCT01093222Phase 2Results posted
• Trial of BIBW 2992 (Afatinib) + Cetuximab in Non-Small Cell Lung CancerCompletedNCT01090011Phase 1Results posted
• Trial of Tasigna (Nilotinib) 400 mg Twice Daily Alone or With Gleevec (Imatinib Mesylate) 400 mg Daily for Patients With Advanced Gastrointestinal Stromal Tumor (GIST)TerminatedNCT01089595Phase 2Results posted
• LUX-Lung 5: Afatinib Plus Weekly Paclitaxel Versus Investigator's Choice of Single Agent Chemotherapy Following Afatinib Monotherapy in Non-small Cell Lung Cancer Patients Failing Erlotinib or GefitinibCompletedNCT01085136Phase 3Results posted
• Radiolabeled [14C]PF-02341066 Study To Investigate The Absorption, Metabolism And Excretion In Healthy Male VolunteersCompletedNCT01082380Phase 1Results posted
• Gemcitabine and Pazopanib in Metastatic Pancreatic CancerTerminatedNCT01080248Phase 2Results posted
• A Pharmacokinetic (PK) Study of Nilotinib in Pediatric Patients With Philadelphia Chromosome-positive (Ph+) Chronic Myelogenous Leukemia (CML) or Acute Lymphoblastic Leukemia (ALL)CompletedNCT01077544Phase 1Results posted
• A Study of Adavosertib (MK-1775) in Combination With Topotecan/Cisplatin in Participants With Cervical Cancer (MK-1775-008)TerminatedNCT01076400Phase 1/2Results posted
• An Extension Treatment Protocol for Subjects Who Have Participated in a Study of Tivozanib Versus Sorafenib in Kidney Carcinoma (Protocol AV-951-09-301).CompletedNCT01076010Phase 3Results posted
• ARQ 197 in Combination With Chemotherapy in Patients With Metastatic Colorectal CancerCompletedNCT01075048Phase 1/2Results posted
• Understanding Mechanisms of Acquired Resistance to BIBW2992CompletedNCT01074177Not applicableResults posted
• Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second RelapseTerminatedNCT01068782Phase 2Results posted
• Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal TumorCompletedNCT01068769Phase 2Results posted
• Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural MesotheliomaActive, not recruitingNCT01064648Phase 1/2Results posted
• Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and NeckCompletedNCT01064479Phase 2Results posted
• Patient Preference Study of Pazopanib Versus Sunitinib in Advanced or Metastatic Kidney CancerCompletedNCT01064310Phase 3Results posted
• Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT01062425Phase 2Results posted
• Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome & /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic PhaseCompletedNCT01061177Phase 4Results posted
• Phase II Trial of Erlotinib, Prior to Surgery or Radiation in Patients With Squamous Cell Cancers (SCC) of the SkinTerminatedNCT01059305Phase 2Results posted
• RAD001 and AV-951 in Patients With Refractory, Metastatic Colorectal CancerCompletedNCT01058655Phase 1/2Results posted
• ARQ 197 for Participants With Relapsed or Refractory Germ Cell TumorsTerminatedNCT01055067Phase 2Results posted
• Evaluation of Patients With Bulky GIST Using SunitinibTerminatedNCT01054911Not applicableResults posted
• GW786034 in Patients With Non Small Cell Lung Cancer 3rd LineTerminatedNCT01049776Phase 2Results posted
• A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005TerminatedNCT01047007Phase 1Results posted
• Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and NeckCompletedNCT01044433Phase 2Results posted
• Study to Evaluate Nilotinib in Chronic Myelogenous Leukemia (CML) Patients With SubOptimal ResponseCompletedNCT01043874Phase 4Results posted
• Trial of Adjuvant Sutent for Patients With High Risk Urothelial Carcinoma After Neoadjuvant Chemotherapy and CystectomyTerminatedNCT01042795Phase 2Results posted
• Safety and Efficacy Study of Icotinb in Non-small Cell Lung Cancer (NSCLC) PatientsCompletedNCT01040780Phase 3Results posted
• Comparing The Effectiveness And Safety Of 2 Doses Of An Experimental Drug, CP-690,550, To Methotrexate (MTX) In Patients With Rheumatoid Arthritis Who Have Not Previously Received MTXCompletedNCT01039688Phase 3Results posted
• Trial of Erlotinib in Patients With JAK-2 V617F Positive Polycythemia VeraTerminatedNCT01038856Phase 2Results posted
• Pazopanib/Doxil in Adv Relapsed Plat Sensitive or Resistant Ovarian, Fallopian or Primary Peritoneal AdenocarcinomaTerminatedNCT01035658Phase 1/2Results posted
• CS1008- in Combination With Sorafenib Compared to Sorafenib Alone in Subjects With Advanced Liver CancerCompletedNCT01033240Phase 2Results posted
• Sorafenib With Capecitabine for Patients With Measurable Hepatocellular CarcinomaTerminatedNCT01032850Phase 2Results posted
• Erlotinib Versus Oral Etoposide in Patients With Recurrent or Refractory Pediatric EpendymomaTerminatedNCT01032070Phase 2Results posted
• Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) PatientsTerminatedNCT01031628Phase 3Results posted
• A Study to Compare Tivozanib (AV-951) to Sorafenib in Subjects With Advanced Renal Cell CarcinomaCompletedNCT01030783Phase 3Results posted
• Rollover Study of BMS-354825 in Patients With CML and Ph+ALLCompletedNCT01030718Phase 1/2Results posted
• A Study of AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit MutationCompletedNCT01028222Phase 2Results posted
• Randomized, Double-Blind Trial of Erlotinib/Pazopanib or Erlotinib/Placebo in Patients With Previously Treated Advanced Non-Small-Cell Lung CancerCompletedNCT01027598Phase 2Results posted
• Combination of Temsirolimus and Sorafenib in the Treatment of Radioactive Iodine Refractory Thyroid CancerCompletedNCT01025453Phase 2Results posted
• Compare Safety and Efficacy of BIBF 1120 Versus Sunitinib.CompletedNCT01024920Phase 2Results posted
• Combination of BI6727 (Volasertib) and BIBF1120 in Solid TumorsCompletedNCT01022853Phase 1Results posted
• Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver CancerCompletedNCT01015833Phase 3Results posted
• LUME-Ovar 1: Nintedanib (BIBF 1120) or Placebo in Combination With Paclitaxel and Carboplatin in First Line Treatment of Ovarian CancerCompletedNCT01015118Phase 3Results posted
• First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor MSC2156119J in Subjects With Advanced Solid TumorsCompletedNCT01014936Phase 1Results posted
• Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by SurgeryCompletedNCT01013649Phase 3Results posted
• Study of Pazopanib and Ixabepilone in Patients With Solid TumorsTerminatedNCT01012362Phase 1Results posted
• Phase II Study Of Oral PHA-848125AC In Patients With Thymic CarcinomaTerminatedNCT01011439Phase 2Results posted
• Study of Gleevec and Weekly Paclitaxel in Patients Aged 70 or Older With Advanced Non-small Cell Lung CancerCompletedNCT01011075Phase 2Results posted
• Temsirolimus (Torisel®) and Erlotinib (Tarceva®) in Platinum-Refractory/Ineligible, Advanced, Squamous Cell CarcinomaTerminatedNCT01009203Phase 2Results posted
• Phase II Randomized Trial Evaluating Neoadjuvant Therapy With Neratinib and/or Trastuzumab Followed by Postoperative Trastuzumab in Women With Locally Advanced HER2-positive Breast CancerCompletedNCT01008150Phase 2Results posted
• Stereotactic Radiation Therapy and Sorafenib in the Treatment of Hepatocellular CarcinomaTerminatedNCT01005875Not applicableResults posted
• Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT01004978Phase 3Results posted
• Safety Study of PLX108-01 in Patients With Solid TumorsCompletedNCT01004861Phase 1Results posted
• Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular CarcinomaCompletedNCT01004003Phase 2Results posted
• Topotecan With Erlotinib for Topotecan Pretreated Ovarian CancerTerminatedNCT01003938Phase 2Results posted
• A Phase II Trial of Afatinib(BIBW 2992) in Third-line Treatment for Patients With Stage IIIB/IV Adenocarcinoma of the Lung Harbouring Wild-type Epidermal Growth Factor Receptor[EGFR]CompletedNCT01003899Phase 2Results posted
• PF-00299804 in Stage IIIB or Stage IV Non-Small Cell Lung Cancer Not Responding to Standard Therapy for Advanced or Metastatic CancerCompletedNCT01000025Phase 3Results posted
• Extension Study of Lapatinib Plus Herceptin With or Without Endocrine TherapyActive, not recruitingNCT00999804Phase 2Results posted
• Phase I Dose Escalation Study of Concomitant BIBF 1120 and BIBW 2992 in Patients With Advanced Solid Tumours.CompletedNCT00998296Phase 1Results posted
• Erlotinib Therapy and Subsequent Development of Mechanisms of Secondary Resistance in Patients With NSCLCCompletedNCT00997334Phase 2Results posted
• Study of Bevacizumab and Erlotinib for Patients With Hormone Refractory Prostate CancerTerminatedNCT00996502Phase 1/2Results posted
• A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade GliomasCompletedNCT00995007Phase 2Results posted
• Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 (Afatinib) Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib or GefitinibCompletedNCT00993499Phase 1Results posted
• A Phase I / II Trial of Nintedanib in Asian Hepatocellular Carcinoma PatientsCompletedNCT00987935Phase 2Results posted
• Nexavar® Versus Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid CancerCompletedNCT00984282Phase 3Results posted
• A Study of Erlotinib Plus Radiotherapy (RT) for Patients With Advanced or Inoperable Non-Small-Cell Lung CancerCompletedNCT00983307Phase 2Results posted
• A Trial Of CVX-060, An Anti-Angiogenic COVX-Body, In Combination With Sunitinib In Patients With Advanced Renal Cell CarcinomaTerminatedNCT00982657Phase 2Results posted
• Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaCompletedNCT00982488Phase 2Results posted
• An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib TreatmentCompletedNCT00980018Phase 4Results posted
• Sunitinib Malate in Treating Patients With Persistent or Recurrent Clear Cell Ovarian CancerCompletedNCT00979992Phase 2Results posted
• Study is Designed to Assess the Safety and Tolerability of AZD4547 at Increasing Doses in Patients With Advanced TumoursTerminatedNCT00979134Phase 1Results posted
• Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemic StudyCompletedNCT00978731Phase 1Results posted
• Erlotinib Study for Myelodysplastic Syndrome (MDS)CompletedNCT00977548Phase 2Results posted
• Erlotinib With or Without Hydroxychloroquine in Chemo-Naive Advanced NSCLC and (EGFR) MutationsActive, not recruitingNCT00977470Phase 2Results posted
• Open Label Trial to Explore Safety of Combining Afatinib (BIBW 2992) and Radiotherapy With or Without Temozolomide in Newly Diagnosed Glioblastoma MultiformCompletedNCT00977431Phase 1Results posted
• Carboplatin, Paclitaxel, and Bevacizumab With or Without Erlotinib Hydrochloride in Treating Non-Smokers With Advanced Non-Small Cell Lung CancerTerminatedNCT00976677Phase 2Results posted
• Study of Lenalidomide in Combination With Sunitinib to Evaluate the Safety and Efficacy in Patients With Renal Cell CarcinomaTerminatedNCT00975806Phase 1/2Results posted
• Treatment of Older Adults With Acute Lymphoblastic LeukemiaCompletedNCT00973752Phase 2Results posted
• Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsCompletedNCT00973739Phase 2Results posted
• Erlotinib, Celecoxib and Reirradiation for Recurrent Head and Neck CancerCompletedNCT00970502Phase 1/2Results posted
• Continued HER2 Suppression With Lapatinib Plus Trastuzumab Versus Trastuzumab AloneTerminatedNCT00968968Phase 3Results posted

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