Tyrosine Kinase Inhibitors: all 10,469 studies that test it

Page 41 of 105. Open to participants first (1,907), then studies with results posted, then the rest; newest registration first within each.

• Erlotinib Is Being Studied With Or Without An Investigational Drug, PF-02341066, In Patients With Lung CancerCompletedNCT00965731Phase 1Results posted
• Depocyt® With Sorafenib in Neoplastic MeningitisTerminatedNCT00964743Not applicableResults posted
• Sunitinib and Capecitabine for First Line Colon CancerTerminatedNCT00961571Phase 2Results posted
• Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) InhibitorsCompletedNCT00960440Phase 3Results posted
• Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast CancerTerminatedNCT00959946Phase 1/2Results posted
• Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid TumorsCompletedNCT00958724Phase 1Results posted
• CLAG Gleevec in Relapsed or Refractory Acute Myeloid Leukemia (AML)CompletedNCT00955916Phase 2Results posted
• A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract CancerTerminatedNCT00955721Phase 1/2Results posted
• Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate CancerTerminatedNCT00953576Phase 1/2Results posted
• Study to Assess dHER2+AS15 Cancer Vaccine Given in Combination With Lapatinib to Patients With Metastatic Breast CancerCompletedNCT00952692Phase 1/2Results posted
• COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I TrialCompletedNCT00952289Phase 3Results posted
• The Effects of Soy Isoflavones to Improve the Metabolism of Glucose and LipidsCompletedNCT00951912Not applicableResults posted
• Phase I Open Label Trial to Assess Safety of BIBW 2992 (Afatinib) in Combination With Herceptin® in Patients With HER2-positive Advanced Breast Cancer.CompletedNCT00950742Phase 1Results posted
• Pemetrexed Disodium With or Without Erlotinib Hydrochloride in Treating Patients With Stage IIIB-IV or Recurrent Non-Small Cell Lung CancerCompletedNCT00950365Phase 2Results posted
• A Study of Dasatinib and Rituximab for Relapsed/Refractory Chronic Lymphocytic LeukemiaTerminatedNCT00949988Phase 1/2Results posted
• An Expanded Access Program of Tarceva (Erlotinib) in Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00949910Phase 4Results posted
• BIBW 2992 (Afatinib) Versus Chemotherapy as First Line Treatment in NSCLC With EGFR MutationCompletedNCT00949650Phase 3Results posted
• Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM)TerminatedNCT00948389Phase 1/2Results posted
• A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine TumorsTerminatedNCT00947167Phase 2Results posted
• Study of Lenvatinib (E7080) in Participants With Advanced Hepatocellular Carcinoma (HCC)CompletedNCT00946153Phase 1/2Results posted
• Pazopanib as Second Line Therapy in Patients With Metastatic Prostate Cancer Refractory to Total Androgen BlockadeTerminatedNCT00945477Phase 2Results posted
• Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part SarcomaCompletedNCT00942877Phase 2Results posted
• Study to Determine the Safety, Maximum Tolerated Dose, Pharmacokinetics of Sorafenib (BAY43-9006)CompletedNCT00941863Phase 1Results posted
• Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal CancerCompletedNCT00940316Phase 2Results posted
• Study of Cabozantinib (XL184) in Adults With Advanced MalignanciesCompletedNCT00940225Phase 2Results posted
• Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell LymphomaCompletedNCT00939770Phase 1/2Results posted
• Relative Drug Exposures Of Two Formulations of PF-02341066CompletedNCT00939731Phase 1Results posted
• Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent CetuximabCompletedNCT00939627Phase 2Results posted
• Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard TherapyCompletedNCT00939523Phase 2Results posted
• Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II TrialCompletedNCT00934544Phase 3Results posted
• An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) GeneCompletedNCT00932893Phase 3Results posted
• An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) GeneCompletedNCT00932451Phase 2Results posted
• Gleevec and Gemzar in Patients With Epithelial Ovarian CancerCompletedNCT00928642Phase 2Results posted
• ATX Study:A Study of Avastin (Bevacizumab), Tarceva (Erlotinib) and Xeloda (Capecitabine) in Patients With Locally Advanced and/or Metastatic Pancreatic CancerCompletedNCT00925769Phase 1Results posted
• Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate CancerTerminatedNCT00924807Phase 1/2Results posted
• Trial of Dasatinib Plus Ixabepilone in 2nd or 3rd Line Metastatic Breast CancerCompletedNCT00924352Phase 1/2Results posted
• A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...CompletedNCT00923481Phase 2Results posted
• Sunitinib to Treat Recurrent Brain CancerTerminatedNCT00923117Phase 2Results posted
• Axitinib (AG-013736) For the Treatment of Metastatic Renal Cell CancerCompletedNCT00920816Phase 3Results posted
• Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naive to Systemic TherapyCompletedNCT00919061Phase 2Results posted
• A Study to Evaluate the Safety and Efficacy of Dasatinib (Sprycel) in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)TerminatedNCT00918463Phase 2Results posted
• Genomic Guided Therapy With Dasatinib or Nilutamide in Metastatic Castration-Resistant Prostate CancerTerminatedNCT00918385Phase 2Results posted
• Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast CancerCompletedNCT00915018Phase 2Results posted
• Sunitinib Malate in Refractory Germ Cell TumorsTerminatedNCT00912912Phase 2Results posted
• Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative DiseasesCompletedNCT00910728Phase 1Results posted
• Sunitinib Malate After Stereotactic Radiosurgery in Treating Patients With Newly Diagnosed Brain MetastasesTerminatedNCT00910039Phase 2Results posted
• Exemestane With Sunitinib (SUTENT®) in Metastatic Breast CancerTerminatedNCT00905021Phase 1/2Results posted
• Efficacy and Safety Comparison of RAD001 Versus Sunitinib in the First-line and Second-line Treatment of Patients With Metastatic Renal Cell CarcinomaCompletedNCT00903175Phase 2Results posted
• Trial of Fulvestrant, MK-0646, and Dasatinib for Metastatic Hormone Receptor-Positive HER2-Negative Breast CancerTerminatedNCT00903006Phase 1/2Results posted
• INCB028050 Compared to Background Therapy in Patients With Active Rheumatoid Arthritis (RA) With Inadequate Response to Disease Modifying Anti-Rheumatic DrugsCompletedNCT00902486Phase 2Results posted
• Imatinib (QTI571) in Pulmonary Arterial HypertensionCompletedNCT00902174Phase 3Results posted
• Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular CarcinomaCompletedNCT00901901Phase 3Results posted
• Phase I/II AZD8931/Paclitaxel in Treatment of Advanced Solid Tumours (Phase I) and Advanced Breast Cancer (Phase II)CompletedNCT00900627Phase 1/2Results posted
• Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma MultiformeCompletedNCT00892177Phase 2Results posted
• Tarceva And Radiotherapy in Locally Advanced Lung Cancer Non-small Cell Lung CancerCompletedNCT00888511Phase 2Results posted
• Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial CancerCompletedNCT00888173Phase 2Results posted
• Neoadjuvant Sunitinib With Paclitaxel/Carboplatin in Patients With Triple-Negative Breast CancerCompletedNCT00887575Phase 1/2Results posted
• Bevacizumab and Lapatinib in Children With Recurrent or Refractory EpendymomaCompletedNCT00883688Phase 2Results posted
• A Study of Dasatinib, Cetuximab and Radiation With or Without Cisplatin in HNSCCTerminatedNCT00882583Phase 1Results posted
• Bevacizumab and Erlotinib or Sorafenib as First-Line Therapy in Treating Patients With Advanced Liver CancerCompletedNCT00881751Phase 2Results posted
• Lapatinib and Capecitabine for Second Line Treatment of Pancreas CancerTerminatedNCT00881621Phase 2Results posted
• Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by SurgeryTerminatedNCT00880542Phase 2Results posted
• Randomized Study of Docetaxel +/- Vandetanib in Metastatic TCCCompletedNCT00880334Phase 2Results posted
• Study Evaluating Bosutinib-Letrozole Combination Versus Letrozole Alone In Post Menopausal Women With Breast CancerTerminatedNCT00880009Phase 2Results posted
• Taxotere/Prednisone Plus Sunitinib in Chemotherapy-Naïve, Hormone Refractory Prostate Cancer PatientsTerminatedNCT00879619Phase 1/2Results posted
• Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast CancerCompletedNCT00878709Phase 3Results posted
• Cisplatin or Carboplatin and Sorafenib in Treating Patients With Liver Cancer That Cannot Be Removed By SurgeryCompletedNCT00875615Phase 2Results posted
• Afatinib (BIBW 2992) QTcF Trial in Patients With Relapsed or Refractory Solid TumoursCompletedNCT00875433Phase 2Results posted
• S0904: Docetaxel With or Without Vandetanib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerCompletedNCT00872989Phase 2Results posted
• Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung CancerCompletedNCT00871923Phase 2Results posted
• Study of Pazopanib and Pemetrexed in Advanced Non-small Cell Lung CancerCompletedNCT00871403Phase 2Results posted
• Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00869401Phase 1/2Results posted
• New Individualized Therapy Trial for Metastatic Colorectal CancerCompletedNCT00867334Phase 1/2Results posted
• Bevacizumab and Sorafenib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Liver CancerCompletedNCT00867321Phase 1/2Results posted
• Five Year Adjuvant Imatinib Mesylate (Gleevec®) in Gastrointestinal Stromal Tumor (GIST)CompletedNCT00867113Phase 2Results posted
• Efficacy and Safety of Pazopanib Monotherapy After First Line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal CancerCompletedNCT00866697Phase 3Results posted
• Sorafenib in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Sunitinib or BevacizumabCompletedNCT00866320Phase 2Results posted
• Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) SubjectsCompletedNCT00865709Phase 2Results posted
• Sunitinib Non Small Cell Lung Cancer Patients Over 70CompletedNCT00864721Phase 2Results posted
• Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients With Soft Tissue Sarcoma of the Extremity and Body WallCompletedNCT00864032Phase 1/2Results posted
• A 3rd/4th Line Placebo-controlled Trial of Sorafenib in Patients With Predominantly Non Squamous Non-Small Cell Lung Cancer (NSCLC).CompletedNCT00863746Phase 3Results posted
• Concentration and Activity of Lapatinib in Vestibular SchwannomasCompletedNCT00863122Early Phase 1Results posted
• Addition of Vandetanib to Standard Therapy Pegliposomal Doxorubicin (PLD)TerminatedNCT00862836Phase 1/2Results posted
• Pazopanib Hydrochloride in Treating Patients With Metastatic Melanoma That Cannot be Removed by SurgeryCompletedNCT00861913Phase 2Results posted
• Docetaxel (Taxotere) and Imatinib Mesylate (Gleevec) in Hormone Refractory Prostate CancerTerminatedNCT00861471Phase 1/2Results posted
• Neoadjuvant Dasatinib Plus LHRH Analogue Therapy in High-Risk Localized Prostate CancerTerminatedNCT00860158Phase 2Results posted
• Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland TumorsCompletedNCT00859937Phase 2Results posted
• Sunitinib in Certain Subtypes of Soft Tissue SarcomasTerminatedNCT00859456Phase 2Results posted
• Neoadjuvant Cisplatin, Gemcitabine, Sunitinib Malate + Radical Cystectomy for TCCTerminatedNCT00859339Phase 2Results posted
• Dasatinib in Advanced Non-small Cell Lung Cancer (NSCL) With Ex Vivo and In Vivo Assessment of Tumor Target ModulationTerminatedNCT00858403Phase 2Results posted
• Lapatinib for Treatment of Ductal Carcinoma In Situ (DCIS) of the BreastTerminatedNCT00857714Not applicableResults posted
• A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis MedicationsCompletedNCT00856544Phase 3Results posted
• A Study of the Combination of Erlotinib and Pertuzumab in Patients With Relapsed Non-small Cell Lung CancerCompletedNCT00855894Phase 2Results posted
• A Phase II Randomized, Double-blind, Placebo-controlled Study of Sorafenib or Placebo in Combination With Transarterial Chemoembolization (TACE) Performed With DC Bead and Doxorubicin for Intermediate Stage Hepatocellular Carcinoma (HCC).CompletedNCT00855218Phase 2Results posted
• Safety and Toxicity Study of Sorafenib in Patients With Kidney CancerCompletedNCT00854620Phase 2Results posted
• A Phase 3 Study Comparing 2 Doses Of CP-690,550 And The Active Comparator, Humira (Adalimumab) Vs. Placebo For Treatment Of Rheumatoid ArthritisCompletedNCT00853385Phase 3Results posted
• AMG 386 Phase 2 Open-Label Renal Cell Carcinoma (RCC) Study 1st Line or After Cytokine Failure in Combination With SunitinibCompletedNCT00853372Phase 2Results posted
• Sunitinib and Irradiated Donor Lymphocytes in Treating Patients With Metastatic Kidney CancerTerminatedNCT00853125Phase 2Results posted
• Treatment With Pazopanib for Neoadjuvant Breast CancerCompletedNCT00849472Phase 2Results posted
• Sunitinib and Surgery in Treating Patients With Localized or Metastatic Kidney CancerCompletedNCT00849186Not applicableResults posted

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