Tyrosine Kinase Inhibitors: all 10,469 studies that test it

Page 42 of 105. Open to participants first (1,907), then studies with results posted, then the rest; newest registration first within each.

• A 2-Year Phase 3 Study Of CP-690,550 In Patients With Active Rheumatoid Arthritis On Background MethotrexateCompletedNCT00847613Phase 3Results posted
• Gemcitabine, Cisplatin, and Sunitinib (GC-S) as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder CancerCompletedNCT00847015Phase 2Results posted
• Study of Sorafenib and Transarterial Chemoembolization (TACE) to Treat Hepatocellular CarcinomaCompletedNCT00844883Phase 2Results posted
• Study Of Sunitinib In Patients With Recurrent Paraganglioma/PheochromocytomaCompletedNCT00843037Phase 2Results posted
• A Phase 1/2, Open-Label, Dose-Escalation Study of JI-101, in Patients With Advanced Solid TumorsCompletedNCT00842335Phase 1/2Results posted
• Study Of Axitinib In Combination With Cisplatin And Capecitabine In Patients With Advanced Gastric CancerCompletedNCT00842244Phase 1Results posted
• Trastuzumab Versus Lapatinib as Neoadjuvant Treatment for Her2+ PatientsCompletedNCT00841828Phase 2Results posted
• 7 Day's of Erlotinib Neo-adjuvant, Followed by Adjuvant Erlotinib-gemcitabine in Pancreatic Cancer PatientsTerminatedNCT00841035Phase 2Results posted
• Imatinib Mesylate (Gleevec) and Paclitaxel in Recurrent Patients of Ovarian and Other Cancers of Mullerian OriginTerminatedNCT00840450Phase 2Results posted
• Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid TumorsCompletedNCT00838539Phase 1Results posted
• Sorafenib and Erlotinib in Treating Patients With Pancreatic Cancer That Cannot Be Removed by SurgeryCompletedNCT00837876Phase 2Results posted
• Sorafenib and Dacarbazine in Soft Tissue SarcomaCompletedNCT00837148Phase 2Results posted
• Axitinib (AG-013736) With Or Without Dose Titration (Increase) In Patients With Kidney CancerCompletedNCT00835978Phase 2Results posted
• Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by SurgeryTerminatedNCT00835679Early Phase 1Results posted
• Bendamustine and Erlotinib in Treating Patients With Stage IIIB, Stage IIIC, or Stage IV Breast CancerCompletedNCT00834678Phase 1/2Results posted
• E7080 in Combination With Carboplatin and Paclitaxel in Patients With Non-small Cell Lung Cancer (NSCLC)CompletedNCT00832819Phase 1Results posted
• Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree CancersTerminatedNCT00832637Phase 2Results posted
• TKI258 in Castrate Resistant Prostate CancerCompletedNCT00831792Phase 2Results posted
• Continuing Access to Axitinib (A406- AG- 013736 ) For Patients Previously Receiving AG 013736 In Clinical TrialsCompletedNCT00828919Not applicableResults posted
• Sorafenib and Vinorelbine in Treating Women With Stage IV Breast CancerCompletedNCT00828074Phase 1/2Results posted
• A Study of Vascular Endothelial Growth Factor (VEGF) Inhibition in Patients With Unilateral Upper Extremity Lymphedema Following Treatment for CancerCompletedNCT00827372Phase 2Results posted
• Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal CancerCompletedNCT00826540Phase 2Results posted
• Dasatinib and Erlotinib in Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00826449Phase 1/2Results posted
• 6 Weeks Treatment of Locally Advanced Breast Cancer With BIBW 2992 (Afatinib) or Lapatinib or TrastuzumabCompletedNCT00826267Phase 2Results posted
• Dose-Dense Temozolomide + Lapatinib for Recurrent EpendymomaCompletedNCT00826241Phase 2Results posted
• Phase I/II Trial of Sorafenib Plus Ixabepilone in HER2-Negative Metastatic Breast CancerCompletedNCT00825734Phase 1/2Results posted
• Study of Gefitinib Retreatment in Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00824746Phase 2Results posted
• Sunitinib in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer Who Have Tumor Cells in the Bone MarrowTerminatedNCT00824538Phase 2Results posted
• Gemzar, Cisp, Sunitinib Urothelial CaCompletedNCT00821327Phase 2Results posted
• A Study of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque PsoriasisCompletedNCT00820950Phase 2Results posted
• Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast CancerCompletedNCT00820222Phase 3Results posted
• Dasatinib In Combination With Weekly Paclitaxel For Patients With Metastatic Breast Carcinoma CA 180 194CompletedNCT00820170Phase 1/2Results posted
• Dacomitinib (PF-00299804) As A Single Oral Agent In Selected Patients With Adenocarcinoma Of The LungCompletedNCT00818441Phase 2Results posted
• Efficacy Study of Dasatinib in Locally Advanced Triple-Negative Breast Cancer PatientsTerminatedNCT00817531Phase 2Results posted
• Study of Sorafenib/Cetuximab in Head and Neck CancerCompletedNCT00815295Phase 1/2Results posted
• A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid ArthritisCompletedNCT00814307Phase 3Results posted
• Sorafenib Therapy Prior to Radiofrequency Ablation for Intermediate Sized Hepatocellular CancerCompletedNCT00813293Phase 2Results posted
• Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive LeukemiasCompletedNCT00811070Phase 2Results posted
• Gemcitabine and Erlotinib in Treating Patients With Metastatic or Recurrent Pancreatic CancerCompletedNCT00810719Phase 2Results posted
• Sorafenib in Treating Patients With Advanced Malignant Solid TumorsCompletedNCT00810394Phase 2Results posted
• Trial Exploring Afatinib (BIBW 2992) + Paclitaxel (Part A), Afatinib + Paclitaxel + Bevacizumab (Part B), Afatinib + Carboplatin (Part C) and Afatinib+ Paclitaxel +Carboplatin(Part D) in Patients With Advanced Solid TumoursCompletedNCT00809133Phase 1Results posted
• Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLCCompletedNCT00806819Phase 3Results posted
• Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 StudiesTerminatedNCT00805467Phase 2Results posted
• LUME-Lung 1: BIBF 1120 Plus Docetaxel as Compared to Placebo Plus Docetaxel in 2nd Line Non Small Cell Lung CancerCompletedNCT00805194Phase 3Results posted
• Randomized Phase Lll Study of Imatinib Dose Optimization vs Nilotinib in CML Patients With Suboptimal Response to ImatinibCompletedNCT00802841Phase 3Results posted
• Study of Low Dose Chemotherapy Plus Sorafenib as Initial Therapy for Patients With Advanced Non-Squamous Cell NSCLCTerminatedNCT00801801Phase 2Results posted
• Phase I Trial of Oral Metronomic Topotecan and Oral Pazopanib to Treat Recurrent/Persistent Gynecologic TumorsCompletedNCT00800345Phase 1Results posted
• A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer With Asymptomatic Untreated Brain MetastasisCompletedNCT00800202Phase 2Results posted
• Rollover Protocol for Prior SU011248 ProtocolsCompletedNCT00798889Not applicableResults posted
• Efficacy and Safety Study of Fostamatinib Disodium Tablets to Treat T-Cell LymphomaCompletedNCT00798096Phase 2Results posted
• Trial of Sunitinib for Refractory Malignant AscitesTerminatedNCT00796861Phase 2Results posted
• BIBW2992 (Afatinib) in Advanced (EGFR-FISH +) NSCLC (Non Small Cell Lung Cancer) PatientsCompletedNCT00796549Phase 2Results posted
• Cediranib, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung CancerCompletedNCT00795340Phase 3Results posted
• Bacillus Calmette-Guerin Followed by Sunitinib for the Treatment of High Risk Non-muscle Invasive Lower Urinary Tract Urothelial CarcinomaCompletedNCT00794950Phase 2Results posted
• Safety And Efficacy Study Of Sunitinib Malate In Chinese Patients With Imatinib Resistant Or Intolerant Malignant Gastrointestinal Stromal TumorCompletedNCT00793871Phase 4Results posted
• Study Evaluating Bosutinib-Exemestane Combination Vs Exemestane Alone in Post Menopausal Women With Breast CancerTerminatedNCT00793546Phase 2Results posted
• Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic LeukemiaActive, not recruitingNCT00792948Phase 2Results posted
• Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal CancerCompletedNCT00791778Phase 2Results posted
• Nilotinib in TKI Resistant or Intolerant Patients With Metastatic Mucosal, Acral, or Chronically Sun Damaged MelanomaCompletedNCT00788775Phase 2Results posted
• Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid TumorsTerminatedNCT00788125Phase 1/2Results posted
• Sunitinib Malate and Capecitabine in Treating Patients With Unresectable or Metastatic Liver CancerTerminatedNCT00787787Phase 2Results posted
• Phase II Study of Dasatinib in Previously Treated Patients With Advanced NSCLCTerminatedNCT00787267Phase 2Results posted
• A Study To Investigate The Safety And Efficacy Of CP- 690,550 In Patients With Moderate And Severe Ulcerative Colitis.CompletedNCT00787202Phase 2Results posted
• A Study of Nilotinib Versus Imatinib in GIST PatientsCompletedNCT00785785Phase 3Results posted
• A Prospective, Randomized, Placebo and Active Comparator Controlled Study of CP-690,550 in Subjects With Dry Eye.CompletedNCT00784719Phase 1/2Results posted
• Evaluating the Safety and Efficacy of Oral Lenvatinib in Medullary and Iodine-131 Refractory, Unresectable Differentiated Thyroid Cancers, Stratified by HistologyCompletedNCT00784303Phase 2Results posted
• Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST)TerminatedNCT00782834Phase 2Results posted
• Personalized Treatment Selection for Metastatic Breast CancerTerminatedNCT00780676Phase 2Results posted
• A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal CancerTerminatedNCT00779311Phase 1Results posted
• A Dose Ranging Study of the Effect of Ruxolitinib Phosphate Cream When Applied to Participants With Plaque PsoriasisCompletedNCT00778700Phase 2Results posted
• Erlotinib Hydrochloride With or Without Cixutumumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerCompletedNCT00778167Phase 1/2Results posted
• Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Following Platinum-doublet ChemotherapyCompletedNCT00777179Phase 2Results posted
• Cediranib in Combination With Lomustine Chemotherapy in Recurrent GlioblastomaCompletedNCT00777153Phase 3Results posted
• Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast CancerCompletedNCT00777101Phase 2Results posted
• A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to ImatinibCompletedNCT00777036Phase 2Results posted
• Double-blind Comparative Study of E3810 Tablets (10 or 20 mg b.i.d.) to Evaluate Efficacy and Safety in Patients With Refractory Reflux EsophagitisCompletedNCT00770913Phase 2/3Results posted
• Assess the Efficacy, Safety and Tolerability of Gefitinib (Iressa® 250mg) as Maintenance Therapy in Locally Advanced or Metastatic (Stage IIIB/IV) Non Small Cell Lung Cancer (NSCLC)CompletedNCT00770588Phase 4Results posted
• MK-0646 and Gemcitabine +/- Erlotinib for Patients With Advanced Pancreatic CancerCompletedNCT00769483Phase 1/2Results posted
• A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy RegimenCompletedNCT00769067Phase 2Results posted
• Evaluation Of The Efficacy Of The Combination Of Axitinib With Pemetrexed And Cisplatin In The Treatment Of Non-Squamous Non-Small Cell Lung CancerCompletedNCT00768755Phase 1/2Results posted
• Open-Label Trial Of Oral PF-00299804 By Continuous Dosing In Patients With Recurrent Or Metastatic Head And Neck Squamous Cell CancerCompletedNCT00768664Phase 2Results posted
• Study Evaluating Safety And Tolerability, Solid TumorCompletedNCT00768469Phase 1Results posted
• Sunitinib in Recurrent and Refractory Ovarian, Fallopian Tube and Peritoneal CarcinomaCompletedNCT00768144Phase 2Results posted
• Safety and Efficacy of Exemestane Plus Dasatinib Versus Placebo for Advanced ER+ Breast CancerCompletedNCT00767520Phase 2Results posted
• Preoperative Chemotherapy (Gemcitabine and Erlotinib) With or Without Radiation TherapyTerminatedNCT00766636Phase 2Results posted
• Safety Evaluation of Dasatinib in Subjects With Scleroderma Pulmonary FibrosisCompletedNCT00764309Phase 1/2Results posted
• Study of Low-Dose Fractionated Radiotherapy in Patients With Locally Advanced Metastatic Pancreatic CancerCompletedNCT00761345Phase 1Results posted
• Nilotinib Versus Standard Imatinib (400/600 mg Every Day (QD)) Comparing the Kinetics of Complete Molecular Response for Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) Pts With Evidence of Persistent Leukemia by Real-time Quantitative Polymerase Chain Reaction (RQ-PCR)CompletedNCT00760877Phase 3Results posted
• Lapatinib in Women With Metastatic Breast Cancer Who Have Failed Prior Antihormone TherapyTerminatedNCT00759642Phase 2Results posted
• Treatment of Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumors in First Line With NilotinibCompletedNCT00756509Phase 4Results posted
• Phase II Neoadjuvant in Inflammatory Breast CancerTerminatedNCT00756470Phase 2Results posted
• Sorafenib in Treating Non-Smokers or Former Light Smokers With Relapsed or Refractory Stage IIIB or Stage IV Non-Small Cell Lung CancerTerminatedNCT00754923Phase 2Results posted
• Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or AdenomaCompletedNCT00754494Phase 2Results posted
• Randomized Trial of Fulvestrant With or Without Dasatinib in Men and Postmenopausal Women Who Have Hormone Receptor-positive Advanced Breast Cancer Previously Treated With an Aromatase InhibitorCompletedNCT00754325Phase 2Results posted
• Zactima in Non Small Cell Lung Cancer (NSCLC) ELderly Patients In Combination With or Versus GemcitabineCompletedNCT00753714Phase 2Results posted
• Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior TherapyCompletedNCT00753688Phase 3Results posted
• Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract CancerCompletedNCT00753675Phase 2Results posted
• ZACtima FASlodex Trial in Postmenopausal Advance Breast Cancer Patients Instead of ZACtima FASlodex TrialTerminatedNCT00752986Phase 2Results posted
• A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the LungTerminatedNCT00752206Phase 2Results posted
• Nilotinib 800 Mg And Imatinib 800 Mg For The Treatment Of Patients With Gastrointestinal Stromal Tumors (Gist) Refractory To Imatinib 400 MgTerminatedNCT00751036Phase 3Results posted

← Tyrosine Kinase Inhibitors overview