Drug
Tumor necrosis factor-alpha, CNGRC fusion protein, human clinical trials
- studies test it
- 17
- open now
- 0
- in phase 3
- 0
- first study started
- 2004
How studies write it
Studies that test it under each name
Name
- NGR-hTNF
- 16
Studies by the year they started
17 studies that test it; most in 2007 (4)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 3 |
| 2007 | 4 |
| 2008 | 1 |
| 2009 | 2 |
| 2010 | 1 |
| 2011 | 2 |
| 2013 | 1 |
| 2016 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 12
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 15 · Other 2
AGC Biologics S.p.A. (15) · Andres J. M. Ferreri (1) · European Organisation for Research and Treatment of Cancer - EORTC (1)
Often tested with
Tested in the same studies.
Doxorubicin (5) · Cyclophosphamide (1) · Vincristine (1) · Prednisone (1) · Oxaliplatin (1) · Cisplatin (1)
Studies
Open first, then newest update. How each study uses tumor necrosis factor-alpha, CNGRC fusion protein, human is read from its arms, and is right about nine times in ten.
Testing it · 17
- RCHOP Chemoimmunotherapy Preceded BY BBB Permeabilization by t-NGR Necrosis FactorCompletedPhase 2Andres J. M. FerreriNCT03536039Written as NGR-hTNF
- A Modified Phase I Study of NGR-hTNF in Advanced Solid TumorsCompletedPhase 1AGC Biologics S.p.A.NCT00419328Written as NGR-hTNF
- Study of NGR-hTNF in Combination With Doxorubicin in Solid TumorsCompletedPhase 1AGC Biologics S.p.A.NCT00305084Written as NGR-hTNF
- Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Metastatic Small Cell Lung CarcinomaCompletedPhase 2AGC Biologics S.p.A.NCT00483509Written as NGR-hTNF
- Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural MesotheliomaCompletedPhase 2AGC Biologics S.p.A.NCT00484276Written as NGR-hTNF
- Study of NGR-hTNF as Single Agent in Patients Affected by Colorectal Cancer (CRC)CompletedPhase 2AGC Biologics S.p.A.NCT00483080Written as NGR-hTNF
- NGR-hTNF in Combination With an Anthracycline in Platinum-resistant Ovarian Cancer (NGR018)CompletedPhase 2AGC Biologics S.p.A.NCT03804866Written as NGR-hTNF
- Phase II Study of NGR-hTNF Versus Placebo as Maintenance Treatment in Patients With Advanced MPMCompletedPhase 2AGC Biologics S.p.A.NCT01358084Written as NGR-hTNF
- Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Advanced or Metastatic Ovarian CancerCompletedPhase 2AGC Biologics S.p.A.NCT00484432Written as NGR-hTNF
- Phase II Study of NGR-hTNF in Combination With Doxorubicin in Platinum-resistant Ovarian CancerCompletedPhase 2AGC Biologics S.p.A.NCT01358071Written as NGR-hTNF
- NGR-hTNF in Combination With Standard Chemotherapy to Treat Patients With Advanced Non-small Cell Lung CancerCompletedPhase 2AGC Biologics S.p.A.NCT00994097Written as NGR-hTNF
- Phase II Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Soft Tissue Sarcomas.CompletedPhase 2AGC Biologics S.p.A.NCT00484341Written as low-dose NGR-hTNF
- Study of NGR-hTNF Administered at High Doses in Patient With Advanced or Metastatic Solid TumourCompletedPhase 1AGC Biologics S.p.A.NCT00878111Written as NGR-hTNF
- NGR-hTNF Administered in Combination With a Standard Oxaliplatin Based Regimen in Patients With Metastatic Colorectal CancerCompletedPhase 2AGC Biologics S.p.A.NCT00675012Written as NGR-hTNF
- Study of NGR-hTNF in Combination With Cisplatin in Solid TumorCompletedPhase 1AGC Biologics S.p.A.NCT00483093Written as NGR-hTNF
- Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Hepatocellular Carcinoma (HCC)CompletedPhase 2AGC Biologics S.p.A.NCT00484211Written as NGR-hTNF
- NGR-TNF in Treating Patients With Advanced Solid TumorsCompletedPhase 1European Organisation for Research and Treatment of Cancer - EORTCNCT00098943Written as CNGRC peptide-TNF alpha conjugate