Prostatic Hyperplasia clinical trials
The registry lists 827 studies for Prostatic Hyperplasia across more than 10 countries. 179 are recruiting or about to start. 678 of them are mainly about Prostatic Hyperplasia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
ClinicalTrials.gov finds 886 studies for Prostatic Hyperplasia. How that becomes 826 here
This page counts the studies the registry files under Prostatic Hyperplasia, and those it files under no condition that list Prostatic Hyperplasiathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 886Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −4List Prostatic Hyperplasia as a condition, but the registry did not file them under itMost often written as “Prostatic Hyperplasia of the Medial Lobe” (1), “Benign Prostatic Hyperplasia With Outflow Obstruction” (1), and “Benign Prostatic Hyperplasia Postoperative Pain” (1). The registry filed them under other conditions only, most often Lower Urinary Tract Symptoms (3) and Urinary Retention (1).
- −56Match it another way41 name it in the title, 1 in a keyword, and 14 by a synonym or other text the search reads.
- 826The count on this page16 of them list Prostatic Hyperplasia in their own words; the registry filed them under no condition.
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Status
Who runs them
GlaxoSmithKline (43) · Boehringer Ingelheim (18) · Eli Lilly and Company (17) · Mansoura University (16) · Ain Shams University (14) · Samsung Medical Center (12) · Beni-Suef University (11) · Boston Scientific Corporation (11)
What is being tested here
Drugs under test in Prostatic Hyperplasia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Tamsulosin | 8 | 11 | 48 |
| Silodosin | 4 | 4 | 18 |
| Tranexamic Acid | 3 | 0 | 4 |
| Tadalafil | 2 | 11 | 26 |
| AD-1161 | 2 | 0 | 3 |
| Dutasteride | 1 | 4 | 27 |
| Finasteride | 1 | 5 | 10 |
| RT-310 | 1 | 0 | 3 |
| Lorazepam | 1 | 1 | 1 |
| Coenzyme Q10 | 1 | 0 | 1 |
Drug classes tested here 5-alpha reductase inhibitors 2 open · PDE5 inhibitors 2 open · Antimuscarinics 12
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jan 2027A Phase III Clinical Study of H077 Sustained-Release Tablets Compared With Silodosin Capsules in the Treatment of Benign Prostatic Hyperplasia · Phase 3 · Shanghai Huilun Pharmaceutical Co., Ltd.
- Apr 2027Efficacy/ Safety of Product DNN.65.21.005 in Patients With Benign Prostatic Hyperplasia · Phase 3 · Ache Laboratorios Farmaceuticos S.A.
- Aug 2027Efficacy and Safety of Combination Therapy Compared With Monotherapy in Patients With Benign Prostatic Hyperplasia · Phase 3 · Il-Yang Pharm. Co., Ltd.
- Nov 2026Local Anesthesia With Schelin Catheter in Rezum Treatment: a Randomized Controlled Trial · Assistance Publique Hopitaux De Marseille
- Nov 2026Impact of Long-term Dutasteride Use on Perioperative Outcomes of HoLEP · Ankara City Hospital Bilkent
- Nov 2026A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate · Tanta University
- Dec 2026Application of Quantum Detection-Driven Artificial Intelligence Algorithms for Single-Molecule cfDNA Characterization in the Early Diagnosis of Prostate Cancer · Shanghai Changzheng Hospital
- Dec 2026Oxiblume:CoQ10 (Ralivia) Therapy for Benign Prostatic Hyperplasia: · G.Gennimatas General Hospital
- Dec 2026Comparative Outcomes of Rezūm Versus EchoLaser for Treatment of Benign Prostatic Hyperplasia With Enlarged Median Lobe. · Benha University
- Dec 2026Short Term Outcomes Of Bipolar Prostate Resection (BPR) Versus Diode Laser Ablation Versus Holmium Laser Enucleation Of Prostate Above 80 Grams With Minimum One Year Follow Up Duration. · Ain Shams University
Who these studies take
Of the 102 Prostatic Hyperplasia studies recruiting now, 70 (69%) set no upper age limit and 4 (4%) stop at 75 or younger. 7 (7%) take children under 18. 0 (0%) are for women only and 99 (97%) for men only; 7 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 5 (5%) |
| 18 | 1 (1%) | 41 (40%) |
| 30 | 2 (2%) | 44 (43%) |
| 40 | 2 (2%) | 56 (55%) |
| 50 | 3 (3%) | 100 (98%) |
| 65 | 3 (3%) | 101 (99%) |
| 75 | 3 (3%) | 100 (98%) |
| 85 | 3 (3%) | 85 (83%) |
Across all 827 studies, recruiting or not: 9% stop at 75 or younger and 5% at 65; 8% take children; 0% are for women only and 96% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Prostatic Hyperplasia studies take
Of 34 phase 1 interventional studies under Prostatic Hyperplasia, half reached primary completion within 3 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 3 mo1–6 · 34 studies | 3 mo1–4 · 26 studies | — |
| Phase 2 | 32 mo13–76 · 17 studies | — | — |
| Phase 3 | 28 mo19–50 · 17 studies | — | — |
| Phase 4 | 23 mo10–26 · 28 studies | — | — |
| Interventional, no phase | 26 mo14–48 · 203 studies | 30 mo10–50 · 51 studies | 25 mo14–48 · 152 studies |
| Observational | 25 mo12–50 · 74 studies | — | 33 mo10–50 · 59 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting4
- ProVIDE Studies Post Exit AnalysisNov 5, 2026NCT07680543
- Evaluation of the Aulea Veloxion™ Disposable Resectoscope System for Operational Efficiency in Surgical Management of Benign Prostatic Hyperplasia (BPH)Oct 27, 2026NCT07728071
- A Smart Wearable Device for Monitoring Urination Function in Benign Prostatic HyperplasiaOct 15, 2026NCT07357012
- To Establish the Safety and Effectiveness of the ALPFA GRAIL PFA System for Treating Symptomatic Benign Prostate Hyperplasia (BPH) Also Known as an Enlarged Prostate.Oct 15, 2026NCT07592299
Newly registered8
- RELEASE Ph2 RT-310 BPH StudyNov 10, 2026NCT07928206
- Perioperative Dutasteride for Hemorrhage Control in Bipolar TURP Under Anticoagulation.Nov 2, 2026NCT07911501
- Prostatic Artery Embolization Using Histoacryl as a Novel Embolizing Agent for Treatment of BPHOct 29, 2026NCT07904702
- Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the ProstateOct 26, 2026NCT07893548
- Anterior Bridge-Preserving Versus Conventional Early Apical Release During Holmium Laser Enucleation of the ProstateOct 23, 2026NCT07892599
Show 3 moreShow fewer
- Ultrasound-Guided vs. Conventional Prostate Suspension in BPH: An Exploratory StudyOct 14, 2026NCT07873125
- Efficacy and Safety of Combination Therapy Compared With Monotherapy in Patients With Benign Prostatic HyperplasiaOct 13, 2026NCT07870759
- Optimization of Surgical Treatment Pathways for BPH Based on Real-World DataOct 13, 2026NCT07872085
Studies
Recruiting first, then most recently updated. Showing 50 of 827. Browse all 827 → or search them.
- Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate CancerRecruitingNCT06161506Phase 21 country
- RELEASE Ph2 RT-310 BPH StudyNot yet recruitingNCT07928206Phase 2
- ProVIDE Studies Post Exit AnalysisRecruitingNCT076805431 country
- Clinical Study on Prostate Thermal Vapor Ablation Guided by MRI/TRUS Fusion ImagingRecruitingNCT06817733Not applicable1 country
- Learning Curve of Tri-lobar HoLEP Versus En-bloc HoLEPRecruitingNCT07890103Not applicable1 country
- Impact of Long-term Dutasteride Use on Perioperative Outcomes of HoLEPRecruitingNCT074174491 country
- Perioperative Dutasteride for Hemorrhage Control in Bipolar TURP Under Anticoagulation.Not yet recruitingNCT07911501Phase 41 country
- Prostatic Artery Embolization Using Histoacryl as a Novel Embolizing Agent for Treatment of BPHNot yet recruitingNCT07904702Not applicable
- Ambulatory Long Length URodynamics EvaluationRecruitingNCT07425015Not applicable1 country
- Comparing Rezum and UroliftRecruitingNCT06820606Not applicable1 country
- Evaluation of the Aulea Veloxion™ Disposable Resectoscope System for Operational Efficiency in Surgical Management of Benign Prostatic Hyperplasia (BPH)RecruitingNCT07728071Not applicable1 country
- Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the ProstateNot yet recruitingNCT07893548Not applicable
- Efficacy and Safety of Two Fixed-dose Combinations in Men With Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia. (BENIPRO)Not yet recruitingNCT06546735Phase 31 country
- Anterior Bridge-Preserving Versus Conventional Early Apical Release During Holmium Laser Enucleation of the ProstateNot yet recruitingNCT07892599Not applicable
- Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong KongRecruitingNCT052922351 country
- The FLOW Registry.Not yet recruitingNCT074304231 country
- To Establish the Safety and Effectiveness of the ALPFA GRAIL PFA System for Treating Symptomatic Benign Prostate Hyperplasia (BPH) Also Known as an Enlarged Prostate.RecruitingNCT07592299Not applicable1 country
- Profiling of Radiological Factors in Treatment and Outcomes in Prostate CancerRecruitingNCT033544161 country
- Orientation Video Training Administered at Different Times to Patients Undergoing Prostate Surgery on Postoperative Pain and Anxiety (Video Training)Not yet recruitingNCT07778355Not applicable1 country
- A Study to Track the Safety of Vesomni in Men in South Korea Treated in Routine Clinical Practice for the Urinary Symptoms of Benign Prostatic Hyperplasia (Enlarged Prostate)Not yet recruitingNCT07619105
- Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled TrialRecruitingNCT07632742Not applicable1 country
- Emsella for Reducing tSUI After HOLEPEnrolling by invitationNCT07580404Not applicable1 country
- A Smart Wearable Device for Monitoring Urination Function in Benign Prostatic HyperplasiaRecruitingNCT073570121 country
- Ultrasound-Guided vs. Conventional Prostate Suspension in BPH: An Exploratory StudyNot yet recruitingNCT07873125Not applicable1 country
- Transperineal Irreversible Electroporation for Benign Prostatic HyperplasiaRecruitingNCT06867315Not applicable1 country
- Efficacy and Safety of Combination Therapy Compared With Monotherapy in Patients With Benign Prostatic HyperplasiaNot yet recruitingNCT07870759Phase 3
- Sacral Neuromodulation for Male Overactive Bladder (MOAB)RecruitingNCT06511141Not applicable1 country
- Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic HyperplasiaRecruitingNCT070166201 country
- Tranexamic Acid for Bleeding Reduction During TURP SurgeryRecruitingNCT07460518Phase 41 country
- HoLEP-ThuLEP - Comparing Lasers for BPH SurgeryRecruitingNCT07565961Not applicable1 country
- Modified SOLTIVE StudyNot yet recruitingNCT078380771 country
- Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE)RecruitingNCT05531240Not applicable1 country
- Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate CancerRecruitingNCT07526675Not applicable1 country
- Post-Market Study to Assess iTind Safety in Comparison to UroLiftRecruitingNCT04757116Not applicable2 countries
- Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer.RecruitingNCT05148156Not applicable1 country
- Ceasing Alpha-blockers Early After Resection of the Prostate (The CLEAR Trial)Not yet recruitingNCT07846579Phase 4
- Effect of Catheter Duration on Prostate Laser Enucleation Surgery Outcomes in Patients With Urinary RetentionRecruitingNCT076030111 country
- Prospective Post Market Clinical Registry for the Zenflow Spring System - A Minimally Invasive Treatment for LUTS Associated With BPH Spring System RegistryRecruitingNCT075386221 country
- Prospective Post Market Clinical Trial for the Zenflow Spring System - A Minimally Invasive Treatment for LUTS Associated With BPH.Not yet recruitingNCT07797348Phase 4
- Use of PuraStat Following Aquablation to Determine if There is Change in Hematuria & Probability of Same Day DischargeRecruitingNCT07789041Not applicable1 country
- Transurethral Thermodilatation vs. Prostatic Urethral Lift for Moderate-to-Severe BPHRecruitingNCT07759752Not applicable1 country
- Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported OutcomesRecruitingNCT058989321 country
- Ejaculatory-Sparing HoLEP vs Standard HoLEPRecruitingNCT07631286Not applicable1 country
- Comparison of Holmium Laser Enucleation of the Prostate and Robotic Water Jet Ablation for Benign Prostatic HyperplasiaNot yet recruitingNCT07772232Not applicable1 country
- Sonablate HIFU International Registry for PC & BPH PatientsRecruitingNCT077574901 country
- BPH Global RegistryRecruitingNCT0554320021 countries
- Hydrodissection-Assisted Bipolar Prostatic Enucleation Versus Conventional Bipolar EnucleationNot yet recruitingNCT07749794Not applicable1 country
- Vivifi Device Safety Evaluation for the Treatment of Benign Prostatic HyperplasiaNot yet recruitingNCT07745621Not applicable1 country
- A Study of the Beacon Platform for Holmium Laser Enucleation of the Prostate (HoLEP)RecruitingNCT07741656Not applicable3 countries
- Pupil Size and Choroidal Thickness Changes With Tamsulosin vs. Silodosin in Benign Prostatic Hyperplasia PatientsNot yet recruitingNCT07743060Phase 4