Simvastatin: all 386 studies that test it

Page 4 of 4. Open to participants first (27), then studies with results posted, then the rest; newest registration first within each.

• Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical TrialCompletedNCT00731627Phase 3
• Study to Evaluate the Effect of Simvastatin, Losartan and Pioglitazone on Patients With Peripheral Arterial Disease.CompletedNCT00720577Early Phase 1
• Effects of Statins on the Pharmacokinetics for Midazolam in Healthy VolunteersCompletedNCT00716846Not applicable
• Antihypertensive Effect of Simvastatin in Hypertensive PatientsStatus unknownNCT00704548Phase 4
• Does Simvastatin Affect Insulin Sensitivity in Dyslipidemic Type 2 Diabetic Patients?CompletedNCT00704314Not applicable
• The Effect of Simvastatin on Desensitization of Panel-Positive Kidney Transplant CandidatesCompletedNCT00693576Phase 2/3
• Simvastatin in Chronic Obstructive Pulmonary Disease (COPD)Status unknownNCT00680641Phase 4
• Losartan and Simvastatin in Hypertensive Obeses With Liver SteatosisStatus unknownNCT00669435Phase 4
• Simvastatin in Relapsing Remitting Multiple Sclerosis (RRMS) Patients Using Avonex Compared to PlaceboCompletedNCT00668343Phase 3
• Standard Medical Management in Secondary Prevention of Ischemic Stroke in ChinaCompletedNCT00664846Not applicable
• Effect of Statin Therapy on C-reactive Protein Levels in Patients With Chronic Obstructive Lung Disease (COPD)CompletedNCT00655993Phase 1
• Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)CompletedNCT00653835Phase 4
• A Research Study to Evaluate MK0653 (Ezetimibe) and Simvastatin, Given Together and Alone, on Intestinal Absorption of Cholesterol (0653-050)(COMPLETED)CompletedNCT00652301Phase 3
• Vytorin As Strategy To Reduce Dislipidemia In Adults (0653A-148)CompletedNCT00651560Phase 3
• Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336)TerminatedNCT00651391Phase 3
• Comparison of Ezetimibe Plus Simvastatin Versus Ezetimibe or Simvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03757)(COMPLETED)CompletedNCT00650819Phase 3
• Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377)CompletedNCT00650663Phase 4
• Add-on Simvastatin in Schizophrenia TrialTerminatedNCT00605995Not applicable
• Efficacy and Safety of Simvastatin in the Treatment of Portal HypertensionCompletedNCT00594191Phase 2
• The Acute Effect of Statins on Inflammatory Markers of Athersclerotic TissueCompletedNCT00587717Not applicable
• Effects of Simvastatin on Biochemical Parameters and Outcome of IVF-ICSI in Pcos PatientsCompletedNCT00575601Phase 3
• A Randomized, Double-Blinded Study of Simvastatin 20 mg/Day Versus Vytorin 10/20 in Subjects With Lipid Profiles Not Meeting Current NCEP Guidelines, Following a Low-Carbohydrate DietCompletedNCT00566267Phase 2/3
• Vascular Effects of Ezetimibe/Simvastatin and Simvastatin on AtherosclerosisCompletedNCT00560170Phase 4
• Simvatstatin Used to Treat Pulmonary HypertensionStatus unknownNCT00538044Phase 1
• Evaluate the Efficacy and Safety of Rosuvastatin Versus Simvastatin in Type 2 Diabetic Patients With DyslipidemiaCompletedNCT00506961Phase 4
• A Study To Evaluate The Safety And Tolerability Of SB-656933-AAA Following Repeated Doses In Healthy Adult SubjectsCompletedNCT00504439Phase 1
• Efficacy and Safety of Statin on the Course of Progressive Smoldering Multiple MyelomaWithdrawnNCT00503763Phase 2
• Simvastatin as an Add-on Treatment to Interferon-beta-1a for the Treatment of Relapsing-Remitting Multiple SclerosisCompletedNCT00492765Phase 4
• Simvastatin Reduces Circulating Osteoprotegerin Levels in Patients With Type 2 DiabetesCompletedNCT00471549Phase 4
• Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to PeroxidationCompletedNCT00466401Phase 4
• Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of BothCompletedNCT00461968Not applicable
• Irinotecan/Cisplatin Plus Simvastatin in Extensive Disease-Small Cell Lung Cancer (ED-SCLC)CompletedNCT00452634Phase 2
• Gefitinib With or Without Simvastatin in Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00452244Phase 2
• Cholesterol and Pharmacogenetic StudyCompletedNCT00451828Phase 4
• Simvastatin in Patients With Septic ShockStatus unknownNCT00450840Phase 4
• Monocyte Function and Inflammation in Type 1 Diabetes and Its ModulationCompletedNCT00441844Phase 2
• Simvastatin as an add-on Treatment to Copaxone for the Treatment of Relapsing Multiple SclerosisWithdrawnNCT00429442Phase 3
• Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.Status unknownNCT00404599Phase 4
• Simvastatin as Inhibitor of Cell Adhesion Mediated Drug Resistance in Patients With Refractory Multiple Myeloma.CompletedNCT00399867Phase 2
• Evaluation of the Effects of Simvastatin 40mgCompletedNCT00397826Phase 4
• Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.Status unknownNCT00396513Not applicable
• Efficacy and Safety of Valsartan and the Combination of Valsartan and SimvastatinCompletedNCT00385931Phase 3
• A Drug-Drug Interaction Study of GK Activator (2) and Simvastatin in Patients With Type 2 Diabetes.CompletedNCT00377442Phase 1
• Statin Therapy Vs. Therapeutic Lifestyle Changes and SupplementsCompletedNCT00365742Not applicable
• Simvastatin Therapy in Women With Polycystic Ovary Syndrome.CompletedNCT00365638Not applicable
• A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis.CompletedNCT00365001Phase 1
• Comparison of the Combination of Fenofibrate and Simvastatin Versus AtorvastatinCompletedNCT00362934Phase 3
• Comparison of the Combination of Fenofibrate and Simvastatin Versus PravastatinCompletedNCT00362206Phase 3
• Comparison of the Combination of Fenofibrate and 40 mg Simvastatin Versus 40 mg Simvastatin MonotherapyCompletedNCT00352183Phase 3
• Comparison of the Combination of Fenofibrate and 20 mg Simvastatin Versus 40 mg Simvastatin MonotherapyCompletedNCT00349375Phase 3
• Effects of Statin Medications on Mental Processes, Behavior, and Serotonin LevelsCompletedNCT00330980Phase 4
• Paroxysmal Atrial Fibrillation: Role of Inflammation, Oxidative Stress Injury and Effect of StatinsCompletedNCT00321802Phase 2
• LDL Receptor Under Ezetimibe and SimvastatinCompletedNCT00317993Phase 4
• Combination of Telmisartan and Simvastatin in the Treatment of Hypertension and HypercholesterolemiaCompletedNCT00316095Phase 3
• Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRCCompletedNCT00313859Phase 2
• Pioglitazone in Impaired Glucose ToleranceWithdrawnNCT00306826Phase 4
• Do HMG CoA Reductase Inhibitors Affect Abeta Levels?CompletedNCT00303277Phase 4
• Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal DialysisStatus unknownNCT00291863Phase 4
• Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With HypercholesterolemiaCompletedNCT00286481Phase 3
• Effects of Statins on Pro- and Antioxidant Status : Link With Statin-Associated Myopathy.CompletedNCT00285181Not applicable
• The Effect of High Dose Simvastatine on Multiple MyelomaCompletedNCT00281476Phase 1/2
• A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).TerminatedNCT00267280Phase 3
• A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol.CompletedNCT00267254Phase 3
• Simvastatin Treatment of Patients With Acute Optic NeuritisStatus unknownNCT00261326Phase 3
• PROMISS: Simvastatin Prevents the Contrast Induced Acute Renal Failure in Patients With Renal Insufficiency Undergoing Coronary AngiographyCompletedNCT00259441Phase 4
• Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.CompletedNCT00256178Phase 3
• A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and HypercholesterolemiaCompletedNCT00254475Phase 3
• Evaluation of Efficacy and Safety of Combined Omacor (Omega-3-acid Ethyl Esters) and Simvastatin Therapy in Hypertriglyceridemic SubjectsCompletedNCT00246701Phase 3
• A Safety Study of Combination Treatment With Avonex and Zocor in Relapsing Remitting Multiple SclerosisStatus unknownNCT00242268Phase 3
• A Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin on Subarachnoid Hemorrhage-Induced VasospasmCompletedNCT00235963Phase 1/2
• Effects of Ezetimibe on Postprandial Hyperlipidemia and Endothelial FunctionCompletedNCT00189085Phase 4
• A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and HypercholesterolemiaCompletedNCT00171093Phase 3
• EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)CompletedNCT00166530Phase 4
• Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHDCompletedNCT00159835Phase 4
• Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)CompletedNCT00157924Phase 4
• Ezetimibe and Simvastatin in Dyslipidemia of DiabetesCompletedNCT00157482Phase 2
• EARLY IFNB-1a and Simvastatin Combination Therapy in Clinically Isolated Syndrome Suggestive of Multiple SclerosisCompletedNCT00146068Phase 4
• Efficacy And Safety Study Of Atorvastatin Versus Simvastatin In Type 2 Diabetic Subjects With HypercholesterolemiaCompletedNCT00141141Phase 4
• A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)CompletedNCT00132717Phase 3
• Transesophageal Magnetic Resonance Imaging (MRI) in Conjunction With Lipid Lowering MeasuresCompletedNCT00125060Not applicable
• A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED)CompletedNCT00093899Phase 3
• Effectiveness of Two Approved Drugs in Lowering High Cholesterol (0733-224)CompletedNCT00092157Phase 3
• Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOASTCompletedNCT00082251Phase 3
• Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS)CompletedNCT00080275Phase 3
• Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease StudyCompletedNCT00053599Phase 3
• Drugs for High Blood Pressure and High Cholesterol in American Indians With Type 2 DiabetesCompletedNCT00004266Phase 3

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