Supplement

(R)-3-hydroxybutyl (R)-3-hydroxybutyrate clinical trials

studies test it: 24
open now: 8
in phase 3: 0
first study started: 2011

Keep track of what changes. Save the (R)-3-hydroxybutyl (R)-3-hydroxybutyrate studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.

Watch these studies

How studies write it

Studies that test it under each name

Name

Ketone monoester: 13
Ketone Monoester (KE): 6
Ketone ester drink: 5
deltaG: 2
(R)-3-hydroxybutyl (R)-3-hydroxybutyrate: 2

Studies by the year they started

24 studies that test it; most in 2024 (4)

Studies that test (R)-3-hydroxybutyl (R)-3-hydroxybutyrate, by start year
Year	Studies
2011	1
2016	1
2018	2
2019	2
2020	1
2021	3
2022	3
2023	2
2024	4
2025	2
2026	3

By phase

A phase 1/2 study counts in both.

Early Phase 1: 1
Phase 1: 2
Phase 2: 3
Phase 4: 2
No phase: 16

What it is tested for

Each study’s main condition, where its own words name it.

Ketosis: 6
Diabetes Mellitus, Type 2: 2
Heart Failure: 2
Metabolic Syndrome: 1
Out-of-Hospital Cardiac Arrest: 1
Cystic Fibrosis: 1
Critical Illness: 1
Prediabetic State: 1
Shock, Cardiogenic: 1
Parkinson Disease: 1

Who runs them

Industry 0 · Other 24

University of British Columbia (4) · University of Alabama at Birmingham (3) · University of Oxford (2) · University of Aarhus (2) · McMaster University (2) · Central Jutland Regional Hospital (1) · National Institute on Aging (NIA) (1) · Barts & The London NHS Trust (1)

Studies

Open first, then newest update. How each study uses (R)-3-hydroxybutyl (R)-3-hydroxybutyrate is read from its arms, and is right about nine times in ten.

Testing it · 24

See all 24 studies that test (R)-3-hydroxybutyl (R)-3-hydroxybutyrate →

As the comparator · 1 — what is tested is compared with (R)-3-hydroxybutyl (R)-3-hydroxybutyrate

The Causal Role of Ketone Bodies in Obesity-associated Disease Prevention - Combining Genetic Epidemiology With a Randomised Trial to Infer CausalityCompletedNot applicableUniversity of BathNCT06668168Written as Ketone Monoester (KE)

Codes

What other systems call (R)-3-hydroxybutyl (R)-3-hydroxybutyrate · ClinicalTrials.gg INT006190

MeSH (NLM) C576699(R)-3-hydroxybutyl (R)-3-hydroxybutyrateOne source ClinicalTrials.gov

System	Code	Name there	Checked by
MeSH (NLM)	C576699	(R)-3-hydroxybutyl (R)-3-hydroxybutyrate	One source ClinicalTrials.gov

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.