Protein Kinase Inhibitors: all 15,278 studies that test it

Page 59 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• Study of Pazopanib and Ixabepilone in Patients With Solid TumorsTerminatedNCT01012362Phase 1Results posted
• Selumetinib in Treating Patients With Recurrent or Persistent Endometrial CancerCompletedNCT01011933Phase 2Results posted
• Phase II Study Of Oral PHA-848125AC In Patients With Thymic CarcinomaTerminatedNCT01011439Phase 2Results posted
• Study of Gleevec and Weekly Paclitaxel in Patients Aged 70 or Older With Advanced Non-small Cell Lung CancerCompletedNCT01011075Phase 2Results posted
• Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell CancerCompletedNCT01010126Phase 2Results posted
• RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHNTerminatedNCT01009346Phase 1/2Results posted
• Temsirolimus (Torisel®) and Erlotinib (Tarceva®) in Platinum-Refractory/Ineligible, Advanced, Squamous Cell CarcinomaTerminatedNCT01009203Phase 2Results posted
• Phase II Randomized Trial Evaluating Neoadjuvant Therapy With Neratinib and/or Trastuzumab Followed by Postoperative Trastuzumab in Women With Locally Advanced HER2-positive Breast CancerCompletedNCT01008150Phase 2Results posted
• Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast CancerCompletedNCT01007942Phase 3Results posted
• A Study of Vemurafenib (RO5185426) in Comparison With Dacarbazine in Previously Untreated Patients With Metastatic Melanoma (BRIM 3)CompletedNCT01006980Phase 3Results posted
• Stereotactic Radiation Therapy and Sorafenib in the Treatment of Hepatocellular CarcinomaTerminatedNCT01005875Not applicableResults posted
• Sirolimus Conversions in African-American Renal Transplant RecipientsCompletedNCT01005706Not applicableResults posted
• Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT01004978Phase 3Results posted
• Safety Study of PLX108-01 in Patients With Solid TumorsCompletedNCT01004861Phase 1Results posted
• Phase I/II Comparison of Efficacy and Safety of BIBF 1120 and Sorafenib in Patients With Advanced Hepatocellular CarcinomaCompletedNCT01004003Phase 2Results posted
• Topotecan With Erlotinib for Topotecan Pretreated Ovarian CancerTerminatedNCT01003938Phase 2Results posted
• A Phase II Trial of Afatinib(BIBW 2992) in Third-line Treatment for Patients With Stage IIIB/IV Adenocarcinoma of the Lung Harbouring Wild-type Epidermal Growth Factor Receptor[EGFR]CompletedNCT01003899Phase 2Results posted
• Lenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic LeukemiaTerminatedNCT01003769Phase 1/2Results posted
• A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic MelanomaCompletedNCT01001299Phase 1Results posted
• PF-00299804 in Stage IIIB or Stage IV Non-Small Cell Lung Cancer Not Responding to Standard Therapy for Advanced or Metastatic CancerCompletedNCT01000025Phase 3Results posted
• Extension Study of Lapatinib Plus Herceptin With or Without Endocrine TherapyActive, not recruitingNCT00999804Phase 2Results posted
• Phase I Dose Escalation Study of Concomitant BIBF 1120 and BIBW 2992 in Patients With Advanced Solid Tumours.CompletedNCT00998296Phase 1Results posted
• Erlotinib Therapy and Subsequent Development of Mechanisms of Secondary Resistance in Patients With NSCLCCompletedNCT00997334Phase 2Results posted
• Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid TumorsTerminatedNCT00996892Phase 1Results posted
• SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDSCompletedNCT00996840Phase 2Results posted
• Study of Bevacizumab and Erlotinib for Patients With Hormone Refractory Prostate CancerTerminatedNCT00996502Phase 1/2Results posted
• A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade GliomasCompletedNCT00995007Phase 2Results posted
• Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 (Afatinib) Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib or GefitinibCompletedNCT00993499Phase 1Results posted
• Irinotecan Hydrochloride With or Without Alvocidib in Treating Patients With Advanced Stomach or Gastroesophageal Junction Cancer That Cannot Be Removed By SurgeryCompletedNCT00991952Phase 2Results posted
• A Study of Advanced or Metastatic Non-small Cell Lung CancerCompletedNCT00988858Phase 2Results posted
• A Phase I / II Trial of Nintedanib in Asian Hepatocellular Carcinoma PatientsCompletedNCT00987935Phase 2Results posted
• Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach CancerCompletedNCT00985192Phase 2Results posted
• Nexavar® Versus Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid CancerCompletedNCT00984282Phase 3Results posted
• A Study of Erlotinib Plus Radiotherapy (RT) for Patients With Advanced or Inoperable Non-Small-Cell Lung CancerCompletedNCT00983307Phase 2Results posted
• Trial of MSC1936369B in Subjects With Solid TumorsCompletedNCT00982865Phase 1Results posted
• A Trial Of CVX-060, An Anti-Angiogenic COVX-Body, In Combination With Sunitinib In Patients With Advanced Renal Cell CarcinomaTerminatedNCT00982657Phase 2Results posted
• Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaCompletedNCT00982488Phase 2Results posted
• Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver CancerCompletedNCT00980460Phase 3Results posted
• An Exploratory Trial to Assess the Improvement of Adverse Events in Chronic Myelogenous Leukemia Patients Treated With Imatinib When Switched to Nilotinib TreatmentCompletedNCT00980018Phase 4Results posted
• Sunitinib Malate in Treating Patients With Persistent or Recurrent Clear Cell Ovarian CancerCompletedNCT00979992Phase 2Results posted
• Study is Designed to Assess the Safety and Tolerability of AZD4547 at Increasing Doses in Patients With Advanced TumoursTerminatedNCT00979134Phase 1Results posted
• Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemic StudyCompletedNCT00978731Phase 1Results posted
• Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)TerminatedNCT00978432Phase 2Results posted
• Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial CancerActive, not recruitingNCT00977574Phase 2Results posted
• Erlotinib Study for Myelodysplastic Syndrome (MDS)CompletedNCT00977548Phase 2Results posted
• Erlotinib With or Without Hydroxychloroquine in Chemo-Naive Advanced NSCLC and (EGFR) MutationsActive, not recruitingNCT00977470Phase 2Results posted
• Open Label Trial to Explore Safety of Combining Afatinib (BIBW 2992) and Radiotherapy With or Without Temozolomide in Newly Diagnosed Glioblastoma MultiformCompletedNCT00977431Phase 1Results posted
• Carboplatin, Paclitaxel, and Bevacizumab With or Without Erlotinib Hydrochloride in Treating Non-Smokers With Advanced Non-Small Cell Lung CancerTerminatedNCT00976677Phase 2Results posted
• Clinical Study to Test a New Drug to Treat Major DepressionCompletedNCT00976560Phase 2Results posted
• Everolimus (RAD001) in Primary Therapy of Waldenstrom's MacroglobulinemiaCompletedNCT00976248Phase 2Results posted
• Safety and Efficacy Study of Sirolimus in Complicated Vascular AnomaliesCompletedNCT00975819Phase 2Results posted
• Study of Lenalidomide in Combination With Sunitinib to Evaluate the Safety and Efficacy in Patients With Renal Cell CarcinomaTerminatedNCT00975806Phase 1/2Results posted
• Treatment of Older Adults With Acute Lymphoblastic LeukemiaCompletedNCT00973752Phase 2Results posted
• Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related TumorsCompletedNCT00973739Phase 2Results posted
• Trial of the Combination of Bevacizumab and Everolimus in Patients With Refractory, Progressive Intracranial MeningiomaTerminatedNCT00972335Phase 2Results posted
• Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor SyndromesCompletedNCT00971789Phase 2Results posted
• Erlotinib, Celecoxib and Reirradiation for Recurrent Head and Neck CancerCompletedNCT00970502Phase 1/2Results posted
• Reacquisition of Radioactive Iodine (RAI) Uptake of RAI-Refractory Metastatic Thyroid Cancers by Pretreatment With the Selective MEK Inhibitor AZD6244CompletedNCT00970359Not applicableResults posted
• BI 6727 (Volasertib) in Combination With Cisplatin or Carboplatin in Patients With Advanced or Metastatic Solid TumourCompletedNCT00969761Phase 1Results posted
• Dose Finding Study of BI 6727 (Volasertib) in Patients With Various Solid CancersCompletedNCT00969553Phase 1Results posted
• Continued HER2 Suppression With Lapatinib Plus Trastuzumab Versus Trastuzumab AloneTerminatedNCT00968968Phase 3Results posted
• RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic LeukemiaCompletedNCT00968253Phase 1/2Results posted
• Panobinostat (LBH589) Plus Everolimus (RAD001) in Patients With Relapsed and Refractory LymphomaCompletedNCT00967044Phase 1/2Results posted
• Erlotinib Is Being Studied With Or Without An Investigational Drug, PF-02341066, In Patients With Lung CancerCompletedNCT00965731Phase 1Results posted
• Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant RecipientsCompletedNCT00965094Phase 4Results posted
• Depocyt® With Sorafenib in Neoplastic MeningitisTerminatedNCT00964743Not applicableResults posted
• A Study of MK-2206 in Combination With Trastuzumab and Lapatinib for the Treatment of HER2+ Solid Tumors (MK-2206-015)TerminatedNCT00963547Phase 1Results posted
• Study of MLN8237 in Participants With Advanced Solid TumorsCompletedNCT00962091Phase 1Results posted
• Sunitinib and Capecitabine for First Line Colon CancerTerminatedNCT00961571Phase 2Results posted
• Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) InhibitorsCompletedNCT00960440Phase 3Results posted
• Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic Breast CancerTerminatedNCT00959946Phase 1/2Results posted
• Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid TumorsCompletedNCT00958724Phase 1Results posted
• Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell TumorsCompletedNCT00957905Phase 2Results posted
• Trial of Pimasertib in Hematological MalignanciesTerminatedNCT00957580Phase 2Results posted
• Study to Evaluate the Efficacy, Safety and Tolerability of Everolimus in de Novo Renal Transplant Recipients Participating in the Eurotransplant Senior ProgramTerminatedNCT00956293Phase 4Results posted
• CLAG Gleevec in Relapsed or Refractory Acute Myeloid Leukemia (AML)CompletedNCT00955916Phase 2Results posted
• A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract CancerTerminatedNCT00955721Phase 1/2Results posted
• Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate CancerTerminatedNCT00953576Phase 1/2Results posted
• Study to Assess dHER2+AS15 Cancer Vaccine Given in Combination With Lapatinib to Patients With Metastatic Breast CancerCompletedNCT00952692Phase 1/2Results posted
• Study to Investigate the Efficacy, Safety and Tolerability of AZD1152 Alone and in Combination With Low Dose Cytosine Arabinoside (LDAC)in Acute Myeloid Leukaemia (AML) PatientsCompletedNCT00952588Phase 2/3Results posted
• COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I TrialCompletedNCT00952289Phase 3Results posted
• The Effects of Soy Isoflavones to Improve the Metabolism of Glucose and LipidsCompletedNCT00951912Not applicableResults posted
• Phase I Open Label Trial to Assess Safety of BIBW 2992 (Afatinib) in Combination With Herceptin® in Patients With HER2-positive Advanced Breast Cancer.CompletedNCT00950742Phase 1Results posted
• Pemetrexed Disodium With or Without Erlotinib Hydrochloride in Treating Patients With Stage IIIB-IV or Recurrent Non-Small Cell Lung CancerCompletedNCT00950365Phase 2Results posted
• A Study of Dasatinib and Rituximab for Relapsed/Refractory Chronic Lymphocytic LeukemiaTerminatedNCT00949988Phase 1/2Results posted
• An Expanded Access Program of Tarceva (Erlotinib) in Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00949910Phase 4Results posted
• A Study of Vemurafenib in Previously Treated Patients With Metastatic MelanomaCompletedNCT00949702Phase 2Results posted
• BIBW 2992 (Afatinib) Versus Chemotherapy as First Line Treatment in NSCLC With EGFR MutationCompletedNCT00949650Phase 3Results posted
• Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent SarcomaCompletedNCT00949325Phase 1/2Results posted
• Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM)TerminatedNCT00948389Phase 1/2Results posted
• A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine TumorsTerminatedNCT00947167Phase 2Results posted
• Study of Lenvatinib (E7080) in Participants With Advanced Hepatocellular Carcinoma (HCC)CompletedNCT00946153Phase 1/2Results posted
• Pazopanib as Second Line Therapy in Patients With Metastatic Prostate Cancer Refractory to Total Androgen BlockadeTerminatedNCT00945477Phase 2Results posted
• Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part SarcomaCompletedNCT00942877Phase 2Results posted
• Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC)CompletedNCT00942825Phase 2Results posted
• Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell CarcinomaCompletedNCT00942734Phase 2Results posted
• Study to Determine the Safety, Maximum Tolerated Dose, Pharmacokinetics of Sorafenib (BAY43-9006)CompletedNCT00941863Phase 1Results posted
• Study of PF-05212384 (Also Known as PKI-587)Administered Intravenously To Subjects With Solid TumorsCompletedNCT00940498Phase 1Results posted
• Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal CancerCompletedNCT00940316Phase 2Results posted
• Study of Cabozantinib (XL184) in Adults With Advanced MalignanciesCompletedNCT00940225Phase 2Results posted

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