Protein Kinase Inhibitors: all 15,278 studies that test it

Page 60 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell LymphomaCompletedNCT00939770Phase 1/2Results posted
• Relative Drug Exposures Of Two Formulations of PF-02341066CompletedNCT00939731Phase 1Results posted
• Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent CetuximabCompletedNCT00939627Phase 2Results posted
• Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard TherapyCompletedNCT00939523Phase 2Results posted
• Dinaciclib in Treating Patients With Stage IV MelanomaActive, not recruitingNCT00937937Phase 2Results posted
• RAD001 for Patients With Radioiodine Refractory Thyroid CancerCompletedNCT00936858Phase 2Results posted
• Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown PrimaryCompletedNCT00936702Phase 2Results posted
• Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma PatientsCompletedNCT00936221Phase 2Results posted
• Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaCompletedNCT00935792Phase 1/2Results posted
• Phase I/II Study of Weekly Abraxane and RAD001 in Women With Locally Adv. or Metastatic Breast CaTerminatedNCT00934895Phase 1/2Results posted
• Polycystic Liver Disease in Kidney TransplantTerminatedNCT00934791Not applicableResults posted
• Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II TrialCompletedNCT00934544Phase 3Results posted
• An Investigational Drug, PF-02341066 Is Being Studied Versus Standard Of Care In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) GeneCompletedNCT00932893Phase 3Results posted
• An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) GeneCompletedNCT00932451Phase 2Results posted
• This Is The First Study Using Escalating Doses Of PF-03758309, An Oral Compound, In Patients With Advanced Solid TumorsTerminatedNCT00932126Phase 1Results posted
• Tacrolimus to Sirolimus Conversion for Delayed Graft FunctionTerminatedNCT00931255Phase 4Results posted
• Cisplatin and Paclitaxel With or Without Everolimus in Treating Patients With Stage II or Stage III Breast CancerCompletedNCT00930930Phase 2Results posted
• Gleevec and Gemzar in Patients With Epithelial Ovarian CancerCompletedNCT00928642Phase 2Results posted
• Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With LymphomaCompletedNCT00928018Phase 3Results posted
• A Trial To Assess Safety And Tolerability Of PF-04691502 In Cancer PatientsCompletedNCT00927823Phase 1Results posted
• ATX Study:A Study of Avastin (Bevacizumab), Tarceva (Erlotinib) and Xeloda (Capecitabine) in Patients With Locally Advanced and/or Metastatic Pancreatic CancerCompletedNCT00925769Phase 1Results posted
• Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate CancerTerminatedNCT00924807Phase 1/2Results posted
• Trial of Dasatinib Plus Ixabepilone in 2nd or 3rd Line Metastatic Breast CancerCompletedNCT00924352Phase 1/2Results posted
• Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney CancerCompletedNCT00923845Phase 2Results posted
• A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...CompletedNCT00923481Phase 2Results posted
• Sirolimus and Pemetrexed to Treat Non-Small Cell Lung CancerTerminatedNCT00923273Phase 1/2Results posted
• Sunitinib to Treat Recurrent Brain CancerTerminatedNCT00923117Phase 2Results posted
• Temsirolimus and Pemetrexed for Recurrent or Refractory Non-Small Cell Lung CancerTerminatedNCT00921310Phase 1/2Results posted
• Axitinib (AG-013736) For the Treatment of Metastatic Renal Cell CancerCompletedNCT00920816Phase 3Results posted
• Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to TherapyTerminatedNCT00920309Phase 2/3Results posted
• Open-label Study to Evaluate the Safety, PK, and PD of MEK Inhibitor GSK1120212 in Subjects With Relapsed or Refractory LeukemiasCompletedNCT00920140Phase 2Results posted
• Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naive to Systemic TherapyCompletedNCT00919061Phase 2Results posted
• Single Agent Temsirolimus (Torisel®) in Chemotherapy-naïve Castration-Resistant Prostate Cancer PatientsCompletedNCT00919035Phase 2Results posted
• A Study to Evaluate the Safety and Efficacy of Dasatinib (Sprycel) in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)TerminatedNCT00918463Phase 2Results posted
• Genomic Guided Therapy With Dasatinib or Nilutamide in Metastatic Castration-Resistant Prostate CancerTerminatedNCT00918385Phase 2Results posted
• Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin LymphomaCompletedNCT00918333Phase 1/2Results posted
• Trial of Paclitaxel/Bevacizumab +/- Everolimus for Patients With HER2-Negative Metastatic Breast CancerCompletedNCT00915603Phase 2Results posted
• Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast CancerCompletedNCT00915018Phase 2Results posted
• Sunitinib Malate in Refractory Germ Cell TumorsTerminatedNCT00912912Phase 2Results posted
• Phase II Trial of EVEROLIMUS ± Trastuzumab in Hormone-Refractory Metastatic Breast CancerCompletedNCT00912340Phase 2Results posted
• A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment ElevationCompletedNCT00910962Phase 2Results posted
• Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative DiseasesCompletedNCT00910728Phase 1Results posted
• Sunitinib Malate After Stereotactic Radiosurgery in Treating Patients With Newly Diagnosed Brain MetastasesTerminatedNCT00910039Phase 2Results posted
• Ursodiol 500 mg Tablets Under Fed ConditionsCompletedNCT00909753Phase 1Results posted
• Ursodiol Tablets 500 mg Under Fasting ConditionsCompletedNCT00909610Phase 1Results posted
• Sirolimus as Therapeutic Approach to UveitisCompletedNCT00908466Phase 1Results posted
• Study of SCH 900776 (MK-8776) With and Without Cytarabine in Participants With Acute Leukemias (P05247)TerminatedNCT00907517Phase 1Results posted
• Exemestane With Sunitinib (SUTENT®) in Metastatic Breast CancerTerminatedNCT00905021Phase 1/2Results posted
• Efficacy and Safety Comparison of RAD001 Versus Sunitinib in the First-line and Second-line Treatment of Patients With Metastatic Renal Cell CarcinomaCompletedNCT00903175Phase 2Results posted
• Trial of Fulvestrant, MK-0646, and Dasatinib for Metastatic Hormone Receptor-Positive HER2-Negative Breast CancerTerminatedNCT00903006Phase 1/2Results posted
• INCB028050 Compared to Background Therapy in Patients With Active Rheumatoid Arthritis (RA) With Inadequate Response to Disease Modifying Anti-Rheumatic DrugsCompletedNCT00902486Phase 2Results posted
• Imatinib (QTI571) in Pulmonary Arterial HypertensionCompletedNCT00902174Phase 3Results posted
• Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular CarcinomaCompletedNCT00901901Phase 3Results posted
• Phase I/II AZD8931/Paclitaxel in Treatment of Advanced Solid Tumours (Phase I) and Advanced Breast Cancer (Phase II)CompletedNCT00900627Phase 1/2Results posted
• Kidney Biopsy Controlled Trial of Calcineurin Inhibitor WithdrawalCompletedNCT00896012Phase 4Results posted
• Study Evaluating A Planned Transition From Tacrolimus To Sirolimus In Kidney Transplant RecipientsCompletedNCT00895583Phase 4Results posted
• Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma MultiformeCompletedNCT00892177Phase 2Results posted
• AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC PatientsCompletedNCT00890825Phase 2Results posted
• Tarceva And Radiotherapy in Locally Advanced Lung Cancer Non-small Cell Lung CancerCompletedNCT00888511Phase 2Results posted
• Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial CancerCompletedNCT00888173Phase 2Results posted
• Selumetinib in Cancers With BRAF MutationsCompletedNCT00888134Phase 2Results posted
• Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration Resistant Metastatic Prostate CancerTerminatedNCT00887640Phase 2Results posted
• Neoadjuvant Sunitinib With Paclitaxel/Carboplatin in Patients With Triple-Negative Breast CancerCompletedNCT00887575Phase 1/2Results posted
• A Study of BMS-863233 in Patients With Advanced and/or Metastatic Solid TumorsTerminatedNCT00886782Phase 1/2Results posted
• Bevacizumab With or Without Everolimus in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerCompletedNCT00886691Phase 2Results posted
• Bevacizumab and Lapatinib in Children With Recurrent or Refractory EpendymomaCompletedNCT00883688Phase 2Results posted
• A Study of Dasatinib, Cetuximab and Radiation With or Without Cisplatin in HNSCCTerminatedNCT00882583Phase 1Results posted
• Bevacizumab and Erlotinib or Sorafenib as First-Line Therapy in Treating Patients With Advanced Liver CancerCompletedNCT00881751Phase 2Results posted
• Lapatinib and Capecitabine for Second Line Treatment of Pancreas CancerTerminatedNCT00881621Phase 2Results posted
• Sorafenib and Ifosfamide in Treating Patients With High-Grade Soft Tissue Sarcoma or Bone Sarcoma That Can Be Removed by SurgeryTerminatedNCT00880542Phase 2Results posted
• Randomized Study of Docetaxel +/- Vandetanib in Metastatic TCCCompletedNCT00880334Phase 2Results posted
• Study Evaluating Bosutinib-Letrozole Combination Versus Letrozole Alone In Post Menopausal Women With Breast CancerTerminatedNCT00880009Phase 2Results posted
• Taxotere/Prednisone Plus Sunitinib in Chemotherapy-Naïve, Hormone Refractory Prostate Cancer PatientsTerminatedNCT00879619Phase 1/2Results posted
• Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)CompletedNCT00879333Phase 3Results posted
• Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast CancerCompletedNCT00878709Phase 3Results posted
• Phosphatidylinositol 3 Kinase and Mammalian Target of Rapamycin (PI3K-mTOR) in Advanced Cancer PatientsTerminatedNCT00877773Phase 1/2Results posted
• Everolimus in Combination With Trastuzumab and Paclitaxel in the Treatment of HER2 Positive Locally Advanced or Metastatic Breast CancerCompletedNCT00876395Phase 3Results posted
• Cisplatin or Carboplatin and Sorafenib in Treating Patients With Liver Cancer That Cannot Be Removed By SurgeryCompletedNCT00875615Phase 2Results posted
• Afatinib (BIBW 2992) QTcF Trial in Patients With Relapsed or Refractory Solid TumoursCompletedNCT00875433Phase 2Results posted
• A Study to Evaluate the Effect of MK-8669 (Ridaforolimus) on QTc Interval in Participants With Advanced Cancer (MK-8669-037)CompletedNCT00874731Phase 1Results posted
• Perifosine in Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaCompletedNCT00873457Phase 2Results posted
• S0904: Docetaxel With or Without Vandetanib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerCompletedNCT00872989Phase 2Results posted
• Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung CancerCompletedNCT00871923Phase 2Results posted
• Study of Pazopanib and Pemetrexed in Advanced Non-small Cell Lung CancerCompletedNCT00871403Phase 2Results posted
• Everolimus Plus Rituximab for Relapsed/Refractory Diffuse Large B Cell LymphomaCompletedNCT00869999Phase 2Results posted
• Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00869401Phase 1/2Results posted
• New Individualized Therapy Trial for Metastatic Colorectal CancerCompletedNCT00867334Phase 1/2Results posted
• Bevacizumab and Sorafenib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Liver CancerCompletedNCT00867321Phase 1/2Results posted
• Five Year Adjuvant Imatinib Mesylate (Gleevec®) in Gastrointestinal Stromal Tumor (GIST)CompletedNCT00867113Phase 2Results posted
• Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft RecipientsCompletedNCT00866879Phase 4Results posted
• Efficacy and Safety of Pazopanib Monotherapy After First Line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal CancerCompletedNCT00866697Phase 3Results posted
• Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive ProtocolTerminatedNCT00866684Phase 4Results posted
• Sorafenib in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Sunitinib or BevacizumabCompletedNCT00866320Phase 2Results posted
• A Study of the Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric LeukemiaTerminatedNCT00866281Phase 1/2Results posted
• MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV MelanomaCompletedNCT00866177Phase 2Results posted
• Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) SubjectsCompletedNCT00865709Phase 2Results posted
• Sunitinib Non Small Cell Lung Cancer Patients Over 70CompletedNCT00864721Phase 2Results posted
• Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients With Soft Tissue Sarcoma of the Extremity and Body WallCompletedNCT00864032Phase 1/2Results posted
• A 3rd/4th Line Placebo-controlled Trial of Sorafenib in Patients With Predominantly Non Squamous Non-Small Cell Lung Cancer (NSCLC).CompletedNCT00863746Phase 3Results posted
• Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or AnastrozoleCompletedNCT00863655Phase 3Results posted

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