Protein Kinase Inhibitors: all 15,278 studies that test it

Page 57 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• Expanded Phase I Pazopanib and Everolimus in Advanced Solid Tumors and Previously Treated Advanced Urothelial CancerCompletedNCT01184326Phase 1Results posted
• A Study of Tarceva (Erlotinib) to Compare Two Different Doses in in Currently Smoking Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (CURRENTS)CompletedNCT01183858Phase 3Results posted
• A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by SurgeryCompletedNCT01183559Phase 1Results posted
• Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)TerminatedNCT01182350Phase 2Results posted
• Tandem Auto-Allo Transplant for LymphomaCompletedNCT01181271Phase 2Results posted
• Erlotinib Plus Bevacizumab in Hepatocellular Carcinoma (HCC) as Second-line TherapyCompletedNCT01180959Phase 2Results posted
• Comparison Of 2 Doses Of Temsirolimus (Torisel) In Patients With Mantle Cell LymphomaCompletedNCT01180049Phase 4Results posted
• Efficacy, Safety, Tolerability and Pharmacokinetics (PK) of Nilotinib (AMN107) in Pulmonary Arterial Hypertension (PAH)TerminatedNCT01179737Phase 2Results posted
• Study of Orally Administered TAK-960 in Patients With Advanced Nonhematologic MalignanciesTerminatedNCT01179399Phase 1Results posted
• An Extension Protocol for Subjects Who Were Previously Enrolled in Other Tivantinib (ARQ 197) ProtocolsCompletedNCT01178411Phase 1/2Results posted
• Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple MyelomaCompletedNCT01177397Phase 1/2Results posted
• A Study on the Correlation Between Tarceva (Erlotinib) - Induced Rash and Efficacy in EGFR Mutated Participants With Advanced Non-Small Cell Lung Cancer Receiving First-Line TherapyCompletedNCT01174563Phase 2Results posted
• A Two Arm Trial of Axitinib and Carboplatin/Paclitaxel in MelanomaCompletedNCT01174238Phase 2Results posted
• Pilot Study of Erlotinib for the Treatment of Patients With de Novo Acute Myeloid LeukemiaCompletedNCT01174043Phase 2Results posted
• Dasatinib With Fludarabine and Rituximab in Relapsed and Refractory CLL and SLLTerminatedNCT01173679Phase 2Results posted
• A Phase Ib Expansion Study Investigating the Safety, Efficacy, and Pharmacokinetics of Intravenous CUDC-101 in Subjects With Advanced Head and Neck, Gastric, Breast, Liver and Non-small Cell Lung Cancer TumorsCompletedNCT01171924Phase 1Results posted
• Roll Over Study From 1199.30 BIBF 1120 in Idiopathic Pulmonary Fibrosis (IPF)CompletedNCT01170065Phase 2Results posted
• 24 Months Follow-up, Two Arm Study to Compare the Cardiovascular Profile in a Regimen With Everolimus + Mycophenolic Acid (MPA) Versus (vs.) a Regimen of CNI+MPA in Maintenance Renal Transplant RecipientsCompletedNCT01169701Phase 4Results posted
• BIBW 2992 (Afatinib) in Combination With Pemetrexed in Advanced Solid TumoursCompletedNCT01169675Phase 1Results posted
• Study of MK-2206 in Patients With Metastatic Neuroendocrine Tumors (NET)CompletedNCT01169649Phase 2Results posted
• Ridaforolimus and Vorinostat in Treating Patients With Advanced Solid Tumors or LymphomaCompletedNCT01169532Phase 1Results posted
• A Phase 1 Absolute Bioavailability Study For Oral Crizotinib In Healthy VolunteersCompletedNCT01168934Phase 1Results posted
• Renal Allograft Function and Histology Following Switching From A Tacrolimus to Sirolimus (SRL)-Based Immunosuppression-TerminatedNCT01166724Phase 3Results posted
• Nilotinib in the Treatment of Systemic SclerosisCompletedNCT01166139Phase 2Results posted
• Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IVTerminatedNCT01166126Phase 2Results posted
• A Pharmacokinetic and Metabolism Study of 14C-labeled RO5185426 on Patients With Metastatic MelanomaCompletedNCT01164891Phase 1Results posted
• Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)CompletedNCT01164579Phase 2Results posted
• Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By SurgeryCompletedNCT01164228Phase 2Results posted
• Chemoembolization of the Liver With or Without Sunitinib Malate in Treating Patients With Liver CancerCompletedNCT01164202Phase 2/3Results posted
• A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque PsoriasisTerminatedNCT01163253Phase 3Results posted
• Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and LymphomaCompletedNCT01162551Phase 2Results posted
• A Study to Compare the Safety and Efficacy of an Aromatase Inhibitor in Combination With Lapatinib, Trastuzumab or Both for the Treatment of Hormone Receptor Positive, HER2+ Metastatic Breast CancerCompletedNCT01160211Phase 3Results posted
• Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade GliomasCompletedNCT01158651Phase 2Results posted
• Pazopanib Hydrochloride Before Surgery in Treating Patients With Kidney CancerCompletedNCT01158521Phase 2Results posted
• Sunitinib Malate in Treating Patients With Previously Untreated Metastatic Kidney CancerCompletedNCT01158222Phase 2Results posted
• Pazopanib Hydrochloride in Treating Patients With Stage IV Kidney CancerCompletedNCT01157091Phase 2Results posted
• Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or LeukemiaCompletedNCT01154816Phase 2Results posted
• Everolimus and OSI-906 for Patients With Refractory Metastatic Colorectal CancerCompletedNCT01154335Phase 1Results posted
• Bioequivalence And Food Effect Study Comparing The Commercial Formulation Of Crizotinib To Its Clinical Study Formulations And Commercial Formulation With Or Without Food In Healthy VolunteersCompletedNCT01154218Phase 1Results posted
• A Study to Assess Biomarkers Impact on Participants Response to Erlotinib Treatment for First-line Non-Small Cell Lung Cancer With Endothelial Growth Factor Receptor (EGFR) Activating MutationsCompletedNCT01153984Phase 2Results posted
• A Study of GSK2118436 in BRAF Mutant Metastatic MelanomaCompletedNCT01153763Phase 2Results posted
• A Study of BIBW 2992 (Afatinib) in Patients With Metastatic Colorectal CancerCompletedNCT01152437Phase 2Results posted
• Rechallenge of Imatinib in GIST Having no Effective Treatment: RIGHTCompletedNCT01151852Phase 3Results posted
• Study of Anastrozole +/- AZD8931 in Postmenopausal Women With Endocrine Therapy Naive Breast CancerTerminatedNCT01151215Phase 2Results posted
• Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant RecipientsCompletedNCT01150097Phase 3Results posted
• Estimation Of Effect Of Ketoconazole On Pharmacokinetics Of Crizotinib In Healthy VolunteersCompletedNCT01149785Phase 1Results posted
• Study of JI-101 in Patients With Advanced Low Grade Endocrine Tumors, Ovarian Cancers or K-RAS Mutant Colon CancersTerminatedNCT01149434Phase 1/2Results posted
• Pazopanib Versus Sunitinib in the Treatment of Asian Subjects With Locally Advanced and/or Metastatic Renal Cell CarcinomaCompletedNCT01147822Phase 2Results posted
• Estimation Of Effect Of Rifampin On Pharmacokinetics Of Crizotinib In Healthy VolunteersCompletedNCT01147055Phase 1Results posted
• BI 6727 (Volasertib) Human ADME Trial in Various Solid TumoursCompletedNCT01145885Phase 1Results posted
• Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the EyeCompletedNCT01143402Phase 2Results posted
• Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant GliomasCompletedNCT01140568Phase 2Results posted
• Pilot Study of Gleevec/Imatinib Mesylate (STI-571, NSC 716051) in Neurofibromatosis (NF1) Patient With Plexiform NeurofibromasCompletedNCT01140360Phase 1/2Results posted
• A Study in Non Small Cell Lung CancerCompletedNCT01139775Phase 1/2Results posted
• A Study in Subjects With Recurrent Malignant GliomaCompletedNCT01137604Phase 2Results posted
• An Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Stage III or Stage IV MelanomaCompletedNCT01136967Phase 2Results posted
• A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth Factor (VEGF)-Targeted TreatmentCompletedNCT01136733Phase 1/2Results posted
• Safety and PK Study of BIBF 1120 in Japanese Patients With IPFCompletedNCT01136174Phase 2Results posted
• A Phase II, Dose Ranging Study Of CP-690,550 Eye Drops In Patients With Dry Eye DiseaseCompletedNCT01135511Phase 2Results posted
• A Study of Avastin (Bevacizumab) in Combination With Xelox and Tarceva in Patients With Metastatic Colorectal Cancer.CompletedNCT01135498Phase 2Results posted
• Study of Sirolimus Versus Mycophenolate Liver Transplant Recipients With Recurrent Hepatitis C Virus (HCV)CompletedNCT01134952Phase 4Results posted
• A Phase I Study of AZD6244 in Combination With Capecitabine and Radiotherapy in Locally Advanced Adenocarcinoma of the RectumTerminatedNCT01134601Phase 1Results posted
• Dose Ranging Study of Pazopanib to Treat Neovascular Age-Related Macular DegenerationCompletedNCT01134055Phase 2Results posted
• E7080 (Lenvatinib) in Combination With Dacarbazine Versus Dacarbazine Alone as First Line Therapy in Patients With Stage IV MelanomaCompletedNCT01133977Phase 1/2Results posted
• E7080 in Combination With Carboplatin + Gemcitabine Versus Carboplatin + Gemcitabine Alone as Second Line Therapy in Patients With Platinum-Sensitive Recurrent Ovarian Cancer by CA125TerminatedNCT01133756Phase 1/2Results posted
• Study in Locally Advanced Squamous Cell Carcinoma of Head and NeckTerminatedNCT01133678Phase 2Results posted
• Cediranib Maleate in Treating Patients With Recurrent or Persistent Endometrial CancerCompletedNCT01132820Phase 2Results posted
• Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast CancerTerminatedNCT01132664Phase 1/2Results posted
• Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma ConcentrationsTerminatedNCT01131325Phase 4Results posted
• A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell CancerCompletedNCT01130519Phase 2Results posted
• A Study Of Neratinib (HKI-272) And Capecitabine In Japanese With Solid TumorCompletedNCT01128842Phase 1Results posted
• Lapatinib in Combination With VinorelbineCompletedNCT01128543Phase 2Results posted
• RAD001 Plus Carboplatin in Breast Cancer PatientsCompletedNCT01127763Phase 2Results posted
• LUX-Breast 1: BIBW 2992 (Afatinib) in HER2-positive Metastatic Breast Cancer Patients After One Prior Herceptin TreatmentCompletedNCT01125566Phase 3Results posted
• Everolimus, Bortezomib and/or Rituximab in Patients With Relapsed/Refractory Waldenstrom's MacroglobulinemiaTerminatedNCT01125293Phase 1/2Results posted
• Studying An Investigational Drug Crizotinib (PF-02341066) In Non Non-Small Cell Lung Cancer Tumors That Are Positive For Anaplastic Lymphoma Kinase (ALK)TerminatedNCT01121588Phase 1Results posted
• A Study Of Combined C- MET Inhibitor And PAN-HER Inhibitor (PF-02341066 And PF-00299804) In Patients With Non- Small Cell Lung CancerCompletedNCT01121575Phase 1Results posted
• Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine TumorsCompletedNCT01121562Phase 2Results posted
• BI 6727 (Volasertib) Randomised Trial in Ovarian CancerCompletedNCT01121406Phase 2Results posted
• BIBW 2992 (Afatinib) vs Gemcitabine-cisplatin in 1st Line Non-small Cell Lung Cancer (NSCLC)CompletedNCT01121393Phase 3Results posted
• S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone SurgeryCompletedNCT01120249Phase 3Results posted
• Campath, Calcineurin Inhibitor Reduction and Chronic Allograft NephropathyCompletedNCT01120028Phase 2/3Results posted
• GCC 0845:Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and BiomarkersTerminatedNCT01118975Phase 1/2Results posted
• Sunitinib Malate in Treating Patients With Recurrent Transitional Cell Bladder CancerTerminatedNCT01118351Phase 2Results posted
• Extension to QTI571A2301 to Evaluate the Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)TerminatedNCT01117987Phase 3Results posted
• Continuous Dosing of BAY73-4506 in Patients With Advanced MalignanciesCompletedNCT01117623Phase 1Results posted
• Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast CancerActive, not recruitingNCT01116648Phase 1/2Results posted
• Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell TransplantationTerminatedNCT01116232Phase 2Results posted
• Efficacy, Safety and Evolution of Cardiovascular Parameters in Renal Transplant RecipientsCompletedNCT01114529Phase 3Results posted
• Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast CancerCompletedNCT01111825Phase 1/2Results posted
• Study of Lenvatinib in Subjects With Advanced Endometrial Cancer and Disease ProgressionCompletedNCT01111461Phase 2Results posted
• Everolimus Versus Placebo in Head and Neck CancerTerminatedNCT01111058Phase 2Results posted
• Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)TerminatedNCT01110876Phase 1/2Results posted
• Safety and Tolerability Study of PCI-32765 in B Cell Lymphoma and Chronic Lymphocytic LeukemiaCompletedNCT01109069Phase 2Results posted
• A Phase 2 Study of Pertuzumab and Erlotinib for Refractory Pancreatic AdenocarcinomaTerminatedNCT01108458Phase 2Results posted
• Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell CarcinomaCompletedNCT01108445Phase 2Results posted
• Phase II Pazopanib in Combination With Weekly Paclitaxel in Refractory Urothelial CancerCompletedNCT01108055Phase 2Results posted
• Pazopanib and Paclitaxel as First-Line Treatment for Subjects With Unresectable Stage III and Stage IV MelanomaCompletedNCT01107665Phase 2Results posted
• A Pharmacokinetic/Pharmacodynamic Study of RO5185426 in Previously Treated Patients With Metastatic MelanomaCompletedNCT01107418Phase 1Results posted
• Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)CompletedNCT01106833Phase 2/3Results posted

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