Protein Kinase Inhibitors: all 15,766 studies that test it

Page 28 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.

• A Study of Effect of Selpercatinib (LY3527723) on Corrected QT (QTc) Interval in Healthy ParticipantsCompletedNCT05630274Phase 1Results posted
• Neo-DAB: Darolutamide and Abemaciclib in Prostate CancerTerminatedNCT05617885Phase 1Results posted
• A Study to Evaluate Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Adolescent and Adult Participants With Moderate to Severe Atopic DermatitisCompletedNCT05601882Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque PsoriasisCompletedNCT05600036Phase 2Results posted
• International Sites: Novel Experimental COVID-19 Therapies Affecting Host ResponseTerminatedNCT05593770Phase 2/3Results posted
• A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen SclerosusCompletedNCT05593445Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen PlanusCompletedNCT05593432Phase 2Results posted
• Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell LymphomasActive, not recruitingNCT05583149Phase 2Results posted
• Mirdametinib + BGB-3245 in Advanced Solid TumorsTerminatedNCT05580770Phase 1/2Results posted
• Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic LiposarcomasTerminatedNCT05580588Phase 2Results posted
• Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies.TerminatedNCT05579769Phase 2Results posted
• Study of PARPi 2X-121 as Monotherapy and in Combination With Dovitinib in Patients With Advanced Solid TumorsTerminatedNCT05571969Phase 1Results posted
• A Study of Ibrutinib With Rituximab in Relapsed or Refractory Mantle Cell LymphomaCompletedNCT05564052Phase 2Results posted
• Anlotinib Combined With Chemotherapy and Neoadjuvant Therapy for Hormone Receptor-positive HER-2 Negative Breast CancerActive, not recruitingNCT05558722Phase 2Results posted
• A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia AreataTerminatedNCT05556265Phase 2Results posted
• Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)TerminatedNCT05554354Phase 2Results posted
• Ritlecitinib for Cicatricial AlopeciaCompletedNCT05549934Phase 2Results posted
• Sitravatinib and Tislelizumab in Patients With Metastatic Uveal Melanoma With Liver Metastases.CompletedNCT05542342Phase 2Results posted
• A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract SurgeryCompletedNCT05528172Phase 3Results posted
• A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010/LEAP-010)-China ExtensionCompletedNCT05523323Phase 3Results posted
• A Study to Assess Treat-to-Target and Dosing Flexibility of Oral Upadacitinib Tablets in Adult Participants With Moderate to Severe Atopic DermatitisCompletedNCT05507580Phase 4Results posted
• Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated CytopeniasTerminatedNCT05502783Phase 2Results posted
• Testing Copanlisib as a Potential Targeted Treatment in Cancers With PIK3CA Mutations (MATCH-Subprotocol Z1F)Active, not recruitingNCT05490771Phase 2Results posted
• A Study Evaluating the Effect of Filgotinib Dose De-escalation in Participants With Ulcerative Colitis (UC) in RemissionTerminatedNCT05479058Phase 3Results posted
• Efficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp PsoriasisCompletedNCT05478499Phase 4Results posted
• A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 GeneTerminatedNCT05469178Phase 1/2Results posted
• A Study of Effects of Selpercatinib (LY3527723) on Repaglinide in Healthy ParticipantsCompletedNCT05469113Phase 1Results posted
• A Study of Effect of Selpercatinib (LY3527723) in Participants With Normal and Impaired Renal FunctionCompletedNCT05469100Phase 1Results posted
• A Study of Effect of Food and a Proton Pump Inhibitor on Selpercatinib (LY3527723) in Healthy ParticipantsCompletedNCT05468164Phase 1Results posted
• Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell CarcinomaTerminatedNCT05461794Phase 2Results posted
• Study of Ruxolitinib Cream in Adolescents With Atopic DermatitisCompletedNCT05456529Phase 3Results posted
• A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP)Active, not recruitingNCT05456191Phase 3Results posted
• CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's SarcomaActive, not recruitingNCT05440786Phase 2Results posted
• A Study of Effects of Selpercatinib in Hepatically Impaired Participants and Healthy ParticipantsCompletedNCT05436912Phase 1Results posted
• Study of Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With an Allergy to PeanutsCompletedNCT05432388Phase 2Results posted
• A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula SurgeryCompletedNCT05425056Phase 3Results posted
• A Randomized, Double-Blind, Placebo-Controlled Trial of IkT-148009 in Untreated Parkinson's DiseaseCompletedNCT05424276Phase 2Results posted
• Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's DiseaseCompletedNCT05422885Phase 1/2Results posted
• Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral MicrodialysisActive, not recruitingNCT05413304Phase 1Results posted
• Efficacy and Safety of Losmapimod in Treating Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) (REACH)TerminatedNCT05397470Phase 3Results posted
• Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast CancerTerminatedNCT05384119Phase 1Results posted
• Study of EYP-1901 in Patients With Nonproliferative Diabetic Retinopathy (NPDR)CompletedNCT05383209Phase 2Results posted
• Maribavir Food-Effect Study in Healthy Adults ParticipantsCompletedNCT05382104Phase 1Results posted
• Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD)CompletedNCT05381948Phase 2Results posted
• Study of Intravaginal Tamoxifen in PostMenopausal Women With VVACompletedNCT05378269Phase 1/2Results posted
• A Study to Learn About Abrocitinib Tablets in People With Atopic Dermatitis in IndiaCompletedNCT05375929Phase 3Results posted
• Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid MalignanciesCompletedNCT05371054Phase 1/2Results posted
• Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand EczemaCompletedNCT05355818Phase 3Results posted
• A Study to Understand the Effect of Low-Fat and High-Fat Meals on the Medicine Called PF-07284890 in Healthy AdultsCompletedNCT05349864Phase 1Results posted
• A Study of Selpercatinib (LY3527723) in Healthy ParticipantsCompletedNCT05338515Phase 1Results posted
• A Study of Effects of Selpercatinib (LY3527723) on Midazolam in Healthy ParticipantsCompletedNCT05338476Phase 1Results posted
• A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing AlopeciaCompletedNCT05332366Phase 2Results posted
• A Study of the Effect of Food on Selpercatinib (LY3527723) in Healthy ParticipantsCompletedNCT05324124Phase 1Results posted
• Tarlox and Sotorasib in Patients With KRAS G12C MutationsTerminatedNCT05313009Phase 1/2Results posted
• Lenvatinib Plus Pembrolizumab In Patients With Immune Checkpoint Inhibitor Naïve Metastatic Uveal MelanomaTerminatedNCT05308901Phase 2Results posted
• Extended Treatment and Follow-up of Subjects Treated With Belumosudil in Study KD025-208 or Study KD025-213CompletedNCT05305989Phase 2Results posted
• Topical Ruxolitinib in Chronic Hand DermatitisCompletedNCT05293717Phase 1/2Results posted
• A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)Active, not recruitingNCT05288166Phase 3Results posted
• A Study To Evaluate The Pharmacokinetics, Excretion, Mass Balance and Metabolism of PF-07265803CompletedNCT05286281Phase 1Results posted
• A Study to Evaluate Long-term Safety of Nintedanib in Children and Adolescents With Interstitial Lung Disease (InPedILD®-ON)CompletedNCT05285982Phase 3Results posted
• ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA)CompletedNCT05279417Phase 2Results posted
• A Study to Evaluate the Safety and Tolerability of Tirbanibulin Ointment 1% in Adult Participants With Actinic KeratosisCompletedNCT05279131Phase 3Results posted
• Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian CancerActive, not recruitingNCT05276973Phase 1Results posted
• A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)CompletedNCT05276063Phase 2/3Results posted
• A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung CancerTerminatedNCT05275673Phase 2Results posted
• Sirolimus for Nosebleeds in HHTCompletedNCT05269849Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 AlterationsTerminatedNCT05267106Phase 2Results posted
• Baricitinib for the Treatment of Ocular Mucous Membrane PemphigoidTerminatedNCT05263505Phase 2Results posted
• Study of Lenvatinib w/ Pembro in Black Participants w/Mismatch Repair-Prof Recurrent Endometrial CancerTerminatedNCT05263492Phase 2Results posted
• A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand EczemaCompletedNCT05259722Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer With an FGFR AlterationCompletedNCT05253807Phase 2Results posted
• Study of Bavituximab, Axitinib, and Avelumab in Advanced Hepatocellular CarcinomaTerminatedNCT05249569Phase 2Results posted
• DDI Study of Evobrutinib and CarbamazepineCompletedNCT05248945Phase 1Results posted
• Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208)CompletedNCT05246111Phase 1Results posted
• Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis TestTerminatedNCT05243641Phase 1/2Results posted
• 9-ING-41 Plus Retifanlimab and Gemcitabine/Nab-Paclitaxel in Patients With Advanced Pancreatic AdenocarcinomaTerminatedNCT05239182Phase 2Results posted
• Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT05237284Phase 2Results posted
• Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) MalignanciesTerminatedNCT05221320Phase 2Results posted
• ATI-450 vs Placebo in Participants With Moderate to Severe Hidradenitis Suppurativa (HS)CompletedNCT05216224Phase 2Results posted
• Osimertinib Plus Chemotherapy in Uncommon EGFRm NSCLCTerminatedNCT05215951Phase 2Results posted
• Tepotinib Drug-Drug Interaction Study With Carbamazepine in Healthy ParticipantsCompletedNCT05213481Phase 1Results posted
• Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous SystemActive, not recruitingNCT05211336Phase 1Results posted
• Tepotinib Drug-Drug Interaction Study With Itraconazole in Healthy ParticipantsCompletedNCT05203822Phase 1Results posted
• Study of Ipilimumab, Nivolumab, and Cabozantinib in Patients With Cutaneous MelanomaTerminatedNCT05200143Phase 2Results posted
• Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the BodyTerminatedNCT05198843Phase 1/2Results posted
• Regorafenib and Durvalumab for the Treatment of High-Risk Liver CancerActive, not recruitingNCT05194293Phase 2Results posted
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket TrialCompletedNCT05189106Phase 1/2Results posted
• Baricitinib (LY3009104) in the Treatment of Cutaneous Lichen PlanusCompletedNCT05188521Phase 2Results posted
• Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal CarcinomatosisCompletedNCT05185947Phase 2Results posted
• Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)CompletedNCT05177211Phase 2Results posted
• A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LY3527727) and Rosuvastatin in Healthy ParticipantsCompletedNCT05176314Phase 1Results posted
• Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast CancerActive, not recruitingNCT05169567Phase 3Results posted
• A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)TerminatedNCT05160168Phase 1/2Results posted
• A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic ArthritisCompletedNCT05153148Phase 2Results posted
• AZD4573 as Monotherapy or in Combinations With Anti-cancer Agents in Patients With r/r PTCL or r/r cHLCompletedNCT05140382Phase 2Results posted
• A Study of Maribavir in Japanese People With Cytomegalovirus (CMV) InfectionCompletedNCT05137717Phase 3Results posted
• A Relative Bioavailability Study of Selpercatinib (LY3527723) in Healthy ParticipantsCompletedNCT05136404Phase 1Results posted
• Study of the Effect of Food and a Proton Pump Inhibitor (PPI; Omeprazole) on LOXO-305 in Healthy ParticipantsCompletedNCT05134350Phase 1Results posted
• Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy ParticipantsCompletedNCT05134337Phase 1Results posted
• A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast CancerActive, not recruitingNCT05132582Phase 3Results posted

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