Protein Kinase Inhibitors: all 15,766 studies that test it
Page 26 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.
- Targeted Pathway Inhibition in Patients With Pancreatic CancerRecruitingNCT04005690Early Phase 1
- Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell LymphomaRecruitingNCT04002947Phase 2
- Clinical Study of Combination Therapy With Ectiecinib, Pemetrexed and Platinum in Patients With Metastatic Non-squamous Non-small Cell Lung Cancer With EGFR Mutations.RecruitingNCT03992885Phase 3
- Adjuvant Chemotherapy With or Without Intercalated IcotinibNot yet recruitingNCT03983811Not applicable
- A Prospective Multicenter Phase 2 Study of FCR/BR Alternating With Ibrutinib in Treatment-naive Patients With CLLRecruitingNCT03980002Phase 2
- Advanced Therapeutics in Rheumatoid Arthritis (RA)RecruitingNCT03976245Phase 4
- A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GlioblastomaRecruitingNCT03970447Phase 2/3
- Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated RejectionRecruitingNCT03955172Not applicable
- A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 GangliosidosisRecruitingNCT03952637Phase 1/2
- Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid TumorsRecruitingNCT03934372Phase 1/2
- APG-2449 in Patients With Advanced Solid TumorsRecruitingNCT03917043Phase 1
- A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer.RecruitingNCT03906669Phase 2
- ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate CancerRecruitingNCT03903835Phase 3
- Losartan + Sunitinib in Treatment of OsteosarcomaRecruitingNCT03900793Phase 1
- Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBsAg+ Advanced Stage HCCRecruitingNCT03899428Phase 2
- Pan Tumor Rollover StudyRecruitingNCT03899155Phase 2
- Acalabrutinib and Venetoclax Treatment of Newly Diagnosed Patients With CLL at High Risk of Infection or Early TreatmentRecruitingNCT03868722Phase 2/3
- Pazopanib for the Treatment of Epistaxis in Hereditary Hemorrhagic TelangiectasiaNot yet recruitingNCT03850730Phase 1/2
- Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic DiseaseRecruitingNCT03844360Phase 4
- Ripasudil for Enhanced Corneal Clearing Following Descemet Membrane Endothelial Keratoplasty in Fuchs' DystrophyRecruitingNCT03813056Phase 2
- Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell TransplantationRecruitingNCT03805477Phase 2
- A PhaseI Study of HL-085 Plus Vemurafenib in Solid Tumor With BRAF V600 MutationRecruitingNCT03781219Phase 1
- A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic ArthritisRecruitingNCT03773965Phase 3
- Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor MalignanciesRecruitingNCT03772561Phase 1
- Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active SurveillanceRecruitingNCT03769766Phase 3
- A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)RecruitingNCT03767075Phase 2
- Examination of Efficacy and Safety of Baricitinib in RA PatientsRecruitingNCT03755466Phase 2
- WIRE - Novel Treatments in Renal Cell CancerRecruitingNCT03741426Phase 2
- PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition With or Without Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Treatment Resistant Residual Triple Negative Breast CancerRecruitingNCT03740893Phase 2
- Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic LeukemiaRecruitingNCT03739814Phase 2
- Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin LymphomaRecruitingNCT03681561Phase 1/2
- RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial CancerRecruitingNCT03675893Phase 2
- Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic SyndromeRecruitingNCT03661307Phase 1/2
- Study of Anlotinib Combined With Docetaxel in Non-Driver Mutation Non-squamous NSCLC: the Save StudyRecruitingNCT03646968Phase 2
- Combination of Alpelisib and Trametinib in Progressive Refractory MeningiomasRecruitingNCT03631953Phase 1
- Combination Chemotherapy With Pazopanib in Children and Adolescents With Relapsed/Refractory Solid TumorsNot yet recruitingNCT03628131Phase 1/2
- ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CMLRecruitingNCT03595917Phase 1
- A Study of HQP1351 in Patients With GIST or Other Solid TumorsRecruitingNCT03594422Phase 1
- Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell DiseaseRecruitingNCT03587272Phase 2
- A Study of BI-1206 in Combination With Rituximab With or Without Acalabrutinib in Subjects With Indolent B-Cell NHLRecruitingNCT03571568Phase 1/2
- Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic LeukemiaRecruitingNCT03571321Phase 1
- Melanoma Metastasized to the Brain and SteroidsRecruitingNCT03563729Phase 2
- VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or LymphomaRecruitingNCT03556228Phase 1/2
- Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaRecruitingNCT03516617Phase 2
- Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)RecruitingNCT03486873Phase 3
- A Phase I/II Study of Regorafenib Plus Avelumab in Solid TumorsRecruitingNCT03475953Phase 1/2
- A Phase 3 Study for the Efficacy and Safety of Radotinib in CP-CML Patients With Failure or Intolerance to Previous TKIsRecruitingNCT03459534Phase 3
- Signal TrAnsduction Pathway Activity Analysis in OVarian cancERRecruitingNCT03458221Phase 2/3
- Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid TumorsRecruitingNCT03454035Phase 1
- A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast CancerRecruitingNCT03424005Phase 1/2
- Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruitingNCT03414502Phase 3
- Gefitinib Combine Radiotherapy as Therapy for Patients With NSCLC Harbouring Sensitive Mutations of EGFRNot yet recruitingNCT03381430Not applicable
- XELOX Plus Apatinib vs XELOX as Post-operative Chemotherapy in Locally Advanced Gastric Signet Ring CarcinomaNot yet recruitingNCT03355612Phase 3
- Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast CancerRecruitingNCT03351062Phase 3
- Dabrafenib and/or Trametinib Rollover StudyRecruitingNCT03340506Phase 4
- Selumetinib and Azacitidine in High Risk Chronic Blood CancersRecruitingNCT03326310Phase 1
- Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6RecruitingNCT03310879Phase 2
- Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)RecruitingNCT03297606Phase 2
- The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant RecipientsEnrolling by invitationNCT03292861Phase 2
- Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic LeukemiaRecruitingNCT03263572Phase 2
- Glanatec(R) for Descemet Stripping in Fuch's Endothelial DystrophyRecruitingNCT03249337Phase 4
- Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic MalformationsRecruitingNCT03243019Phase 2
- Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.RecruitingNCT03242382Phase 2
- Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell LymphomaRecruitingNCT03223610Phase 1/2
- Apatinib as the First-Line Therapy in Elderly Locally Advanced or Metastatic Gastric CancerRecruitingNCT03219593Phase 2
- Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling DonorRecruitingNCT03214354Phase 2
- Clinical Trial of Neoadjuvant Targeted Treatment to NSCLC PatientsNot yet recruitingNCT03203590Phase 3
- Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 ChangeRecruitingNCT03191149Phase 2
- APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsRecruitingNCT03175224Phase 2
- Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS PatientsRecruitingNCT03127267Phase 3
- Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)RecruitingNCT03126916Phase 3
- Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell DiseaseRecruitingNCT03121001Phase 2
- Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid CancerRecruitingNCT03099356Phase 2
- A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsRecruitingNCT03093116Phase 1/2
- A Clinical Trial With Apatinib for Subjects With Refractory Malignant AscitesRecruitingNCT03020979Phase 2
- Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)RecruitingNCT03016819Phase 3
- Study of Biomarker-Based Treatment of Acute Myeloid LeukemiaRecruitingNCT03013998Phase 2/3
- Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors TrialRecruitingNCT03011684Phase 3
- INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)RecruitingNCT02977780Phase 2
- Study of Ruxolitinib in Relapsed or Refractory T or NK Cell LymphomaRecruitingNCT02974647Phase 2
- The Drug Rediscovery Protocol (DRUP Trial)RecruitingNCT02925234Phase 2
- Study for the Use of TKIs for Treatment of Cognitive Decline Due to Degenerative DementiasEnrolling by invitationNCT02921477Phase 1
- ASCT After a Rituximab/Ibrutinib/Ara-c Containing iNduction in Generalized Mantle Cell LymphomaRecruitingNCT02858258Phase 3
- Senescence in Chronic Kidney DiseaseEnrolling by invitationNCT02848131Phase 2
- European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory TumorsRecruitingNCT02813135Phase 1/2
- Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 3
- TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage CancerRecruitingNCT02693535Phase 2
- A CpG-methylation-based Assay for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant TreatmentNot yet recruitingNCT02688491Not applicable
- Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard CareRecruitingNCT02638389Phase 3
- Phase I/II Trial of Everolimus in Combination With Lonafarnib in ProgeriaEnrolling by invitationNCT02579044Phase 1/2
- Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive MeningiomasRecruitingNCT02523014Phase 2
- A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous CarcinomaRecruitingNCT02491099Phase 2
- Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence ScoreRecruitingNCT02476786Phase 2
- Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of RecurrenceRecruitingNCT02446431Early Phase 1
- Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...RecruitingNCT02390752Phase 1
- Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver CancerEnrolling by invitationNCT02081755Phase 4
- Adjuvant Curcumin to Assess Recurrence Free Survival in Patients Who Have Had a Radical ProstatectomyRecruitingNCT02064673Phase 3
- Evaluation of Tamoxifen's Efficacy for ER/PR Negative,ER-beta Positive Operable Breast Cancer PatientsRecruitingNCT02062489Phase 3
- Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous MalformationsRecruitingNCT02042326Phase 2
- Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatmentRecruitingNCT02029001Phase 2