Drug
Prochlorperazine clinical trials
Also written Compazine.
- studies test it
- 12
- open now
- 0
- in phase 3
- 3
- first study started
- 2004
How studies write it
Studies that test it under each name
Brand
Combined with it in one product
Studies by the year they started
12 studies that test it; most in 2006 (2)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 2 |
| 2007 | 2 |
| 2010 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2018 | 1 |
| 2021 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 2
- Phase 2
- 2
- Phase 3
- 3
- Phase 4
- 4
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 10
Montefiore Medical Center (2) · Nova Pneuma Inc. (1) · University of Rochester NCORP Research Base (1) · University of Colorado, Denver (1) · CHRISTUS Health (1) · Alexza Pharmaceuticals, Inc. (1) · Joseph Roscoe (1) · Emory University (1)
Often tested with
Tested in the same studies.
Diphenhydramine (2) · Olanzapine (1) · Hydromorphone (1) · Metoclopramide (1) · Granisetron (1) · Palonosetron (1) · Ondansetron (1)
Studies
Open first, then newest update. How each study uses Prochlorperazine is read from its arms, and is right about nine times in ten.
Testing it · 12
- Staccato Prochlorperazine Single Dose PK StudyCompletedPhase 1Nova Pneuma Inc.NCT00610727Written as Prochlorperazine 0.5 mg IV over 5 sec
- Treatment of Refractory Nausea and Vomiting in Patients With Breast CancerCompletedPhase 3University of Rochester NCORP Research BaseNCT03367572Written as Prochlorperazine
- Prochlorperazine vs Imitrex for Acute Migraine in the Emergency DepartmentWithdrawnNot applicableUnited States Naval Medical Center, PortsmouthNCT00573599Written as prochlorperazine and benadryl IV
- Prochlorperazine Maleate Versus Placebo for the Prophylaxis of Acute Mountain SicknessCompletedPhase 2University of Colorado, DenverNCT06450899Written as Prochlorperazine Maleate
- Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain SicknessCompletedPhase 4CHRISTUS HealthNCT06310642Written as Prochlorperazine 10 mg
- Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute MigraineTerminatedPhase 4Albert Einstein Healthcare NetworkNCT01629329Written as Prochlorperazine 10mg
- Staccato Prochlorperazine Thorough QT/QTcCompletedPhase 1Alexza Pharmaceuticals, Inc.NCT00543062Written as Inhaled prochlorperazine 5 mg
- Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute MigraineCompletedPhase 4Montefiore Medical CenterNCT02389829Written as Prochlorperazine
- Prochlorperazine vs MetoclopramideCompletedPhase 4Montefiore Medical CenterNCT00364806Written as Prochlorperazine
- Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCTStatus unknownPhase 3Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterNCT02779959Written as Prochlorperazine
- Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical TrialCompletedPhase 3Joseph RoscoeNCT00475085Written as prochlorperazine
- Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency DepartmentCompletedPhase 2Emory UniversityNCT00590317Written as Prochlorperazine
Given in every arm · 7 — Prochlorperazine is usual care beside what is tested
- Intravenous Fluids in Pediatric MigraineRecruitingNot applicableDayton Children's HospitalNCT06182098Written as Prochlorperazine
- E7 TCR T Cells for Human Papillomavirus-Associated CancersCompletedPhase 1/2National Cancer Institute (NCI)NCT02858310Written as Prochlorperazine
- Intranasal Ketorolac TrialTerminatedPhase 2Washington University School of MedicineNCT06083571Written as Prochlorperazine
- Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology PatientsTerminatedPhase 3University of Michigan Rogel Cancer CenterNCT04503668Written as Compazine
- Intravenous Fluids in Benign Headaches TrialCompletedPhase 4University Medical Center of Southern NevadaNCT03185130Written as Prochlorperazine 0.15 mg/kg up to 10 mg IV
- Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple MyelomaWithdrawnEarly Phase 1Koen van BesienNCT05013437Written as Prochlorperazine
- Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve GastrectomyCompletedPhase 4Stony Brook UniversityNCT03435003Written as Compazine
As the comparator · 4 — what is tested is compared with Prochlorperazine
- Magnesium Versus Prochlorperazine Versus Metoclopramide for MigrainesCompletedPhase 3Wake Forest University Health SciencesNCT05967442Written as Prochlorperazine (Compazine) Injection
- The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus KetamineTerminatedPhase 3Mike O'Callaghan Military HospitalNCT02735343Written as Compazine
- SPG Block for Acute Pediatric MigraineStatus unknownPhase 3Newark Beth Israel Medical CenterNCT03984045Written as Prochlorperazine Injection
- The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus KetamineCompletedPhase 4University Medical Center of Southern NevadaNCT02657031Written as Prochlorperazine
Codes
What other systems call Prochlorperazine · ClinicalTrials.gg INT008096
- MeSH (NLM) D011346ProchlorperazineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) YHP6YLT61TPROCHLORPERAZINEConfirmed FDA, NLM, Wikidata
- RxNorm 8704Confirmed FDA, Wikidata
- Wikidata Q2359690prochlorperazineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C774ProchlorperazineOne source FDA
- DrugBank DB00433One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D011346 | Prochlorperazine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | YHP6YLT61T | PROCHLORPERAZINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 8704 | — | Confirmed FDA, Wikidata |
| Wikidata | Q2359690 | prochlorperazine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C774 | Prochlorperazine | One source FDA |
| DrugBank | DB00433 | — | One source Wikidata |
Also registered as prochlorperazine edisylate (UNII PG20W5VQZS · RxNorm 8705) and prochlorperazine maleate (UNII I1T8O1JTL6 · RxNorm 8706).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.