Drug
Tafenoquine clinical trials
Also written Arakoda.
- studies test it
- 32
- open now
- 12
- in phase 3
- 6
- first study started
- 1997
Keep track of what changes. Save the tafenoquine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Studies by the year they started
32 studies that test it; most in 2024 (4)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 1998 | 1 |
| 2000 | 1 |
| 2003 | 1 |
| 2009 | 2 |
| 2011 | 1 |
| 2014 | 2 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 1 |
| 2020 | 1 |
| 2021 | 3 |
| 2023 | 3 |
| 2024 | 4 |
| 2025 | 3 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 5
- Phase 2
- 15
- Phase 3
- 6
- Phase 4
- 6
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 15 · Other 17
GlaxoSmithKline (10) · 60 Degrees Pharmaceuticals LLC (4) · U.S. Army Medical Research and Development Command (4) · Menzies School of Health Research (3) · University of Oxford (3) · Shoklo Malaria Research Unit (2) · London School of Hygiene and Tropical Medicine (2) · Curtin University (2)
Often tested with
Tested in the same studies.
Primaquine (7) · Chloroquine (5) · Artemether, Lumefantrine Drug Combination (2) · Artemether (2) · Fanasil, pyrimethamine drug combination (1) · Amodiaquine (1) · Mefloquine (1) · Artenimol (1)
Studies
Open first, then newest update. How each study uses tafenoquine is read from its arms, and is right about nine times in ten.
Testing it · 32
- Southeast Asia Dose Optimization of TafenoquineRecruitingPhase 4University of OxfordNCT04704999Written as Tafenoquine
- An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and OlderRecruitingPhase 3GlaxoSmithKlineNCT06666491Written as Tafenoquine
- Tafenoquine Drug Levels in Small ChildrenNot yet recruitingPhase 2University of OxfordNCT07835321Written as Tafenoquine
- Pharmacokinetic (PK) Study of Tafenoquine in Healthy AdultsNot yet recruitingEarly Phase 1State University of New York - Upstate Medical UniversityNCT07373743Written as Tafenoquine Oral Tablet
- Tafenoquine and ACTs (TADORE- Plus)Not yet recruitingPhase 4Menzies School of Health ResearchNCT07060794Written as Tafenoquine plus Artesunate-pyronaridine
- Postpartum 8-aminoquinoline Breast Milk StudyNot yet recruitingPhase 2/3Curtin UniversityNCT07060404Written as Single-dose tafenoquine given with food and water to prevent gastrointestinal discomfort
- Investigating the Pharmacokinetics of Tafenoquine in Healthy Papua New Guinean ChildrenRecruitingPhase 4Curtin UniversityNCT07052162Written as Single dose tafenoquine (10 mg/kg) given with water
- Oral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for BabesiosisRecruitingPhase 260 Degrees Pharmaceuticals LLCNCT06207370Written as Tafenoquine
- B-FREE Chronic Babesiosis StudyRecruitingPhase 260 Degrees Pharmaceuticals LLCNCT06656351Written as Tafenoquine 100mg
- A Revised Tafenoquine Dose to Improve Radical Cure for Vivax MalariaRecruitingPhase 3Menzies School of Health ResearchNCT06148792Written as Tafenoquine
- ACT vs CQ With Tafenoquine for P. Vivax Mono-infectionRecruitingPhase 4Shoklo Malaria Research UnitNCT05788094Written as Chloroquine plus Tafenoquine (450 mg adult dose)
- A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease ProgressionNot yet recruitingPhase 260P Australia Pty LtdNCT05947812Written as Tafenoquine Oral Tablet
- Long-Term Safety Study of TafenoquineCompletedPhase 260 Degrees Pharmaceuticals LLCNCT03320174Written as Tafenoquine
- Vivax Elimination With Tafenoquine (VET) StudyCompletedPhase 4Shoklo Malaria Research UnitNCT06575647Written as Tafenoquine
- Tafenoquine in Patients With Mild to Moderate COVID-19CompletedPhase 260 Degrees Pharmaceuticals LLCNCT04533347Written as Tafenoquine Oral Tablet
- Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and PrimaquineCompletedPhase 3Menzies School of Health ResearchNCT04411836Written as Tafenoquine
- Tafenoquine and Primaquine in Colostrum and Breast MilkWithdrawnPhase 4University of OxfordNCT04984759Written as Tafenoquine
- Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2)CompletedPhase 2London School of Hygiene and Tropical MedicineNCT04609098Written as Tafenoquine 100mg [Arakoda]
- Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in MaliCompletedPhase 2London School of Hygiene and Tropical MedicineNCT05081089Written as Tafenoquine
- A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) MalariaCompletedPhase 2GlaxoSmithKlineNCT02563496Written as Tafenoquine
See all 32 studies that test tafenoquine →
Given in every arm · 2 — tafenoquine is usual care beside what is tested
- Tafenoquine Combinations for Improved Radical Cure Efficacy of Plasmodium VivaxNot yet recruitingNot applicableWalter Reed Army Institute of Research (WRAIR)NCT07533136Written as Tafenoquine (TQ)
- Investigating the Pharmacology of Tafenoquine in Papua New Guinean Children With Uncomplicated MalariaNot yet recruitingPhase 4Curtin UniversityNCT07403643Written as Single dose tafenoquine (10 mg/kg)
Codes
What other systems call tafenoquine · ClinicalTrials.gg INT003375
- MeSH (NLM) C055852tafenoquineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 262P8GS9L9TAFENOQUINEConfirmed FDA, NLM, Wikidata
- RxNorm 2054023One source FDA
- Wikidata Q2387553tafenoquineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73006TafenoquineOne source FDA
- DrugBank DB06608One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C055852 | tafenoquine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 262P8GS9L9 | TAFENOQUINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2054023 | — | One source FDA |
| Wikidata | Q2387553 | tafenoquine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73006 | Tafenoquine | One source FDA |
| DrugBank | DB06608 | — | One source Wikidata |
Also registered as tafenoquine succinate (UNII DL5J0B8VSS · RxNorm 2054091) and tafenoquine succinate, (r)- (UNII 39WAV9S05J).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.