Glucosephosphate Dehydrogenase Deficiency clinical trials
The registry lists 41 studies for Glucosephosphate Dehydrogenase Deficiency across more than 10 countries. 4 are recruiting or about to start. 16 of them are mainly about Glucosephosphate Dehydrogenase Deficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-02.
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Who runs them
PATH (6) · University of Thessaly (3) · Menzies School of Health Research (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · London School of Hygiene and Tropical Medicine (2) · University of Mississippi, Oxford (2) · Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1)
What is being tested here
Drugs under test in Glucosephosphate Dehydrogenase Deficiency studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ascorbic Acid | 1 | 0 | 1 |
| Ursodeoxycholic Acid | 1 | 0 | 1 |
| Primaquine | 0 | 0 | 4 |
| Tin mesoporphyrin | 0 | 0 | 2 |
| Thioctic Acid | 0 | 0 | 2 |
| Tafenoquine | 0 | 0 | 1 |
| Dapsone Gel | 0 | 0 | 1 |
| Chloroquine | 0 | 0 | 1 |
| Aspirin | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Nov 2026Early Check: Expanded Screening in Newborns · RTI International
- Jan 2027The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect Hyperbilirubinemia · Tishreen University Hospital
- Jul 2027High-Dose Vitamin C in G6PDA and Pyruvate Kinase Deficiency: A Safety Study · University of Utah
Who these studies take
Of the 2 Glucosephosphate Dehydrogenase Deficiency studies recruiting now, 1 (50%) set no upper age limit and 1 (50%) stop at 75 or younger. 1 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (50%) | 1 (50%) |
| 30 | 1 (50%) | 1 (50%) |
| 40 | 1 (50%) | 1 (50%) |
| 50 | 1 (50%) | 1 (50%) |
| 65 | 1 (50%) | 1 (50%) |
| 75 | 1 (50%) | 1 (50%) |
| 85 | 1 (50%) | 1 (50%) |
Across all 41 studies, recruiting or not: 51% stop at 75 or younger and 49% at 65; 56% take children; 0% are for women only and 5% for men only; 49% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 41 of 41. search them.
- High-Dose Vitamin C in G6PDA and Pyruvate Kinase Deficiency: A Safety StudyNot yet recruitingNCT07612345Phase 11 country
- The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect HyperbilirubinemiaRecruitingNCT07110987Not applicable1 country
- Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases.RecruitingNCT07468513Phase 43 countries
- Screening of Coexistence Between Sickle Cell Anaemia and G6PD DeficiencyNot yet recruitingNCT06615024
- Short Course Primaquine for the Radical Cure of P. Vivax - Papua New GuineaCompletedNCT05874271Not applicable1 country
- Early Check: Expanded Screening in NewbornsActive, not recruitingNCT036552231 country
- Short Course Primaquine for the Radical Cure of P. Vivax Malaria - IndonesiaCompletedNCT05879224Not applicable1 country
- Baby Detect : Genomic Newborn ScreeningCompletedNCT056874741 country
- Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective StudyCompletedNCT070377061 country
- Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient PatientsCompletedNCT03529396Phase 21 country
- Primaquine Enantiomers in G6PD Deficient Human VolunteersCompletedNCT04073953Phase 11 country
- At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic ConditionsCompletedNCT019316441 country
- Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in ThailandCompletedNCT057531501 country
- Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in BrazilActive, not recruitingNCT050967021 country
- Oxidative Stress, Carbohydrate Metabolism Disorders and G6PD DeficiencyStatus unknownNCT05571748Not applicable
- Validation of Diagnostics to Identify Glucose-6-phosphate Dehydrogenase Activity in the USCompletedNCT04010695Not applicable1 country
- G6PD Deficiency in Infarction Patients in Shaanxi ProvinceStatus unknownNCT050264891 country
- Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency (SAST)Status unknownNCT04088513Phase 41 country
- Effects of N-acetyl Cystein (NAC) Supplementation in G6PD Deficient Individuals After Acute ExerciseStatus unknownNCT02937376Early Phase 11 country
- Assessing a Risk Model for G6PD DeficiencyTerminatedNCT03337152Phase 41 country
- Evaluation of a Diagnostic to Identify Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in BrazilCompletedNCT04033640Not applicable1 country
- Validation of a Diagnostic Test for Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Anti-coagulated BloodCompletedNCT04054661Not applicable1 country
- Comparative Evaluation of the FINDER Instrument and FINDER G6PD Cartridge in Adults and NeonatesCompletedNCT041462461 country
- A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) MalariaCompletedNCT02563496Phase 22 countries
- Stannsoporfin With Light Therapy for Newborn Babies With JaundiceCompletedNCT01887327Phase 21 country
- Innate and Acquired Resistance to Plasmodium Falciparum Malaria in MaliCompletedNCT006690841 country
- Effect of G6PD Deficiency on Red Blood Cell StorageCompletedNCT040812721 country
- Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose RegimenCompletedNCT03934450Phase 11 country
- Malaria Studies in CambodiaCompletedNCT006635461 country
- Effects of Alpha Lipoic Acid Supplementation in G6PD Deficient Individuals After Acute ExerciseCompletedNCT02937363Not applicable1 country
- Safety and Tolerability of Low Dose PrimaquineCompletedNCT02434952Phase 41 country
- Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)CompletedNCT02174900Phase 2/31 country
- Efficacy of Yinzhihuang Oral Liquid on Indirect Bilirubin of Neonates With Glucose-6-phosphate Dehydrogenase DeficiencyStatus unknownNCT02594904Phase 41 country
- Comparing G6PD Tests Using Capillary Blood Versus Venous BloodCompletedNCT02069236Not applicable1 country
- Diet Challenge in G6PD Deficient Egyptian Children: A One- Year Prospective Single Center Study With Genotype - Phenotype CorrelationStatus unknownNCT02498340Phase 2/31 country
- Evaluation of Different G6PD Testing PlatformsCompletedNCT021045181 country
- Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD DeficiencyCompletedNCT00243542Phase 41 country
- A Test to Predict the Hemolytic Potential of Drugs in G6PD DeficiencyCompletedNCT00076323Not applicable1 country
- Demographic, Metabolic, and Genomic Description of Neonates With Severe HyperbilirubinemiaCompletedNCT003833181 country
- Lapdap and Coartemether for Uncomplicated MalariaCompletedNCT00118794Phase 31 country
- Phase II Randomized Study of Tin Mesoporphyrin for Neonatal HyperbilirubinemiaCompletedNCT00004381Phase 21 country