Primaquine: all 59 studies that test it

Page 1 of 1. Open to participants first (3), then studies with results posted, then the rest; newest registration first within each.

• Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives)Not yet recruitingNCT07357103Phase 4
• Postpartum 8-aminoquinoline Breast Milk StudyNot yet recruitingNCT07060404Phase 2/3
• A Revised Tafenoquine Dose to Improve Radical Cure for Vivax MalariaRecruitingNCT06148792Phase 3
• Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical CureCompletedNCT04706130Phase 4Results posted
• Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial TherapyCompletedNCT04661579Phase 2Results posted
• Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, BrazilCompletedNCT03610399Not applicableResults posted
• Assessing a Risk Model for G6PD DeficiencyTerminatedNCT03337152Phase 4Results posted
• Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax MalariaCompletedNCT02216123Phase 3Results posted
• Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, BrazilCompletedNCT02043652Not applicableResults posted
• Postpartum Primaquine in Breast MilkCompletedNCT06191458Phase 4
• Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium VivaxCompletedNCT06044805Phase 4
• Momordica Charantia and Dihydroartemisinin-piperaquined-primaquine for Uncomplicated Plasmodium Falciparum Malaria Patients in Southwest Sumba RegencyCompletedNCT05829187Phase 2
• Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in MaliCompletedNCT05550909Phase 2
• Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in MaliCompletedNCT05081089Phase 2
• Study to Evaluate Primaquine for Radical Cure of Uncomplicated Plasmodium Vivax Malaria in ChildrenCompletedNCT05044637Phase 2
• Tafenoquine and Primaquine in Colostrum and Breast MilkWithdrawnNCT04984759Phase 4
• Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination ActivitiesCompletedNCT04864444Not applicable
• Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and PrimaquineCompletedNCT04411836Phase 3
• Controlled Human Malaria Infection Transmission Model - Phase ASuspendedNCT04280692Phase 1/2
• Biomarkers of P. Vivax RelapseStatus unknownNCT04228315Not applicable
• Short Course Radical Cure of P. Vivax Malaria in NepalCompletedNCT04079621Phase 4
• Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum TransmissionCompletedNCT04049916Phase 2/3
• Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic AreasCompletedNCT03916003Phase 4
• Targeted Active Case Detection Among High Risk Populations in Southern Lao Peoples Democratic RepublicCompletedNCT03783299Phase 4
• Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient PatientsCompletedNCT03529396Phase 2
• Single Low-dose Primaquine Efficacy and Safety.CompletedNCT03352843Phase 4
• "Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania"CompletedNCT03241901Phase 4
• Genetic Variability in CYP2D6 in U.S Active Duty PopulationCompletedNCT02960568Phase 1
• Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers, Study 1CompletedNCT02898779Phase 1
• G6PD Assessment Before Primaquine for Radical Treatment of Vivax MalariaCompletedNCT02876549Phase 4
• Pharmacokinetic Study of Primaquine in Healthy Obese Thai Adult SubjectsCompletedNCT02789566Phase 1
• Study of Artemether-lumefantrine, Amodiaquine and Primaquine in Healthy SubjectsTerminatedNCT02696954Phase 1/2
• Determining a Tolerable Dose of Primaquine in G6PD-deficient Persons Without Malaria in MaliCompletedNCT02535767Phase 1/2
• Safety and Tolerability of Low Dose PrimaquineCompletedNCT02434952Phase 4
• Effectiveness of Malaria Treatment in MexicoCompletedNCT02394197Phase 4
• Investigation of Short Course, High Dose Primaquine Treatment for Liver Stages of Plasmodium Vivax InfectionStatus unknownNCT02364583Phase 4
• Artemether-lumefantrine vs Chloroquine for Uncomplicated P. Vivax Malaria in MalaysiaStatus unknownNCT02348788Phase 3
• Dihydroartemisinin-piperaquine With Low Dose Primaquine to Reduce Malaria TransmissionCompletedNCT02259426Phase 3
• Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and MorbidityCompletedNCT02143934Phase 4
• Efficacy and Safety of a Single Low-dose Primaquine for the Clearance of GametocytesCompletedNCT02090036Phase 4
• Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus PrimaquineCompletedNCT01878357Phase 4
• Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic CarriersCompletedNCT01838902Phase 3
• Safety and Efficacy of Primaquine for P. VivaxStatus unknownNCT01837992Not applicable
• IMPROV (Improving the Radical Cure of Vivax Malaria)CompletedNCT01814683Not applicable
• Primaquine Pharmacokinetics in Lactating Women and Their InfantsCompletedNCT01780753Phase 1
• Ethiopia Antimalarial in Vivo Efficacy Study 2012CompletedNCT01680406Phase 4
• Pharmacokinetic Study of Primaquine and Pyronaridine-Artesunate in Healthy SubjectsCompletedNCT01552330Phase 1
• Malaria Challenge in Healthy VolunteersCompletedNCT01500980Phase 1
• Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in UgandaCompletedNCT01365598Phase 3
• Study of ACTs Plus Primaquine for Uncomplicated Plasmodium Vivax MalariaCompletedNCT01288820Phase 3
• G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)CompletedNCT01205178Phase 1
• Estimating the Risk of Plasmodium Vivax Relapses in AfghanistanCompletedNCT01178021Phase 4
• Incidence of Vivax Along the Thai Burma BorderCompletedNCT01076868Not applicable
• Study on the Treatment of Vivax MalariaCompletedNCT01074905Phase 3
• Trial of Artesunate Combination Therapy in PakistanCompletedNCT00959517Phase 2
• Eight Week Primaquine Regimen for the Treatment of Vivax MalariaCompletedNCT00158587Phase 3
• A Test to Predict the Hemolytic Potential of Drugs in G6PD DeficiencyCompletedNCT00076323Not applicable
• The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDSCompletedNCT00000717Not applicable
• A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDSCompletedNCT00000640Phase 3

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