Drug
Pegaspargase clinical trials
Also written Oncaspar and PEG-asparaginase.
- studies test it
- 70
- open now
- 8
- in phase 3
- 20
- first study started
- 1994
Keep track of what changes. Save the pegaspargase studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
70 studies that test it; most in 2016 (8)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1996 | 1 |
| 1997 | 1 |
| 1998 | 1 |
| 1999 | 1 |
| 2000 | 3 |
| 2002 | 1 |
| 2003 | 2 |
| 2004 | 2 |
| 2005 | 2 |
| 2006 | 2 |
| 2007 | 3 |
| 2008 | 1 |
| 2009 | 5 |
| 2010 | 2 |
| 2011 | 3 |
| 2012 | 3 |
| 2013 | 5 |
| 2014 | 1 |
| 2015 | 2 |
| 2016 | 8 |
| 2017 | 1 |
| 2019 | 4 |
| 2020 | 4 |
| 2021 | 4 |
| 2023 | 3 |
| 2024 | 3 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 9
- Phase 2
- 40
- Phase 3
- 20
- Phase 4
- 3
- No phase
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 69
Children's Oncology Group (9) · Sun Yat-sen University (9) · St. Jude Children's Research Hospital (8) · Dana-Farber Cancer Institute (4) · Beijing Tongren Hospital (4) · National Cancer Institute (NCI) (3) · Children's Cancer Group, China (2) · M.D. Anderson Cancer Center (2)
Often tested with
Tested in the same studies.
Dexamethasone (33) · Vincristine (29) · Cytarabine (28) · Cyclophosphamide (27) · Methotrexate (27) · Mercaptopurine (23) · Etoposide (22) · Doxorubicin (21)
Studies
Open first, then newest update. How each study uses pegaspargase is read from its arms, and is right about nine times in ten.
Testing it · 70
- TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia IIRecruitingPhase 1/2Tanja Andrea GruberNCT05848687Written as PEG asparaginase
- A Phase II Study of Sintilimab, Pegaspargase and Selinexor Followed by Radiotherapy in Newly Diagnosed Stage I/II Extranodal NK/T-Cell LymphomaNot yet recruitingPhase 2Sun Yat-sen UniversityNCT07574528Written as Pegaspargase
- Screening Study of Combined Sequential Chemotherapy and Radiation Therapy for Early-stage NK/T-cell LymphomaRecruitingPhase 2Fudan UniversityNCT06314334Written as Sintilimab+Pegaspargase
- Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma (T-LBL)RecruitingPhase 3Children's Cancer Group, ChinaNCT05681260Written as Prednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin
- "Selinexor+Pegaspargase+Dexamethasone"in Ⅰ/Ⅱ NKTCLRecruitingPhase 1/2Mingzhi ZhangNCT06559553Written as Selinexor+pegaspargase+dexamethasone
- Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic DiseaseRecruitingPhase 4Wei ZhaoNCT03844360Written as Pegaspargase
- Linperlisib Combined With Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-cell LymphomaRecruitingPhase 1/2Beijing Tongren HospitalNCT06376721Written as Pegaspargase
- Pegaspargase-COEP Chemotherapy Combined With Radiotherapy for Extra-nodal NK/T Cell LymphomaRecruitingPhase 2Peking UniversityNCT04484506Written as pegaspargase, cyclophosphamide, vincristine, etoposide, prednisone
- Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic LeukemiaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT02101853Written as Pegaspargase
- A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic LeukemiaActive, not recruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT01920737Written as PEG-Asparaginase
- Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or LymphomaActive, not recruitingPhase 3Children's Oncology GroupNCT05602194Written as Pegaspargase
- Sintilimab, Pegaspargase and Anlotinib for Stage IV Natural Killer /T-cell LymphomaCompletedPhase 2Rong TaoNCT04004572Written as LEAP regimen
- 05-001: Treatment of Acute Lymphoblastic Leukemia in ChildrenCompletedPhase 3Dana-Farber Cancer InstituteNCT00400946Written as pegaspargase
- SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic LymphomaActive, not recruitingPhase 2Dana-Farber Cancer InstituteNCT01574274Written as Oncaspar
- Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) IActive, not recruitingPhase 1/2St. Jude Children's Research HospitalNCT02553460Written as Pegaspargase
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic LymphomaCompletedPhase 3National Cancer Institute (NCI)NCT00408005Written as Pegaspargase
- Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingPhase 2/3St. Jude Children's Research HospitalNCT03117751Written as Pegaspargase
- Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic LymphomaCompletedPhase 3Children's Oncology GroupNCT01190930Written as Pegaspargase
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 2Alliance for Clinical Trials in OncologyNCT00558519Written as pegaspargase
- LBL-2016 for Children or Adolescents in ChinaActive, not recruitingPhase 3Children's Cancer Group, ChinaNCT02845882Written as Prednisone,Vincristine, Pegylated-asparaginase, Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine
See all 70 studies that test pegaspargase →
Given in every arm · 72 — pegaspargase is usual care beside what is tested
- A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)RecruitingPhase 2National Cancer Institute (NCI)NCT06124157Written as Pegaspargase
- Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic LymphomaRecruitingPhase 2M.D. Anderson Cancer CenterNCT00501826Written as Pegaspargase
- A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)RecruitingPhase 2National Cancer Institute (NCI)NCT04546399Written as Pegaspargase
- Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLyRecruitingPhase 3Children's Oncology GroupNCT03959085Written as Pegaspargase
- GELAD-Based Response-Adapted Treatment for Early-Stage Extranodal NK/T-Cell LymphomaNot yet recruitingPhase 2Fudan UniversityNCT07768943Written as pegaspargase
- ALL Backbone in AYAsRecruitingPhase 2Dana-Farber Cancer InstituteNCT07227584Written as Oncaspar
- Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)Not yet recruitingPhase 2/3Children's Oncology GroupNCT07072585Written as Pegaspargase
- Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic LeukemiaRecruitingPhase 1University of ChicagoNCT03571321Written as Pegaspargase
- Study of Sugemalimab (or Placebo) Plus PGemOx Regimen in Participants With Extranodal NK/T-Cell LymphomaNot yet recruitingPhase 3CStone PharmaceuticalsNCT05700448Written as Pegaspargase
- International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic LymphomaRecruitingPhase 3University Hospital MuensterNCT04043494Written as PEG asparaginase
- Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic LeukemiaRecruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT05660473Written as Pegaspargase
- Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017RecruitingPhase 3Martin SchrappeNCT03643276Written as Pegaspargase
- A Multicenter, Phase 3, Randomized Trial of Sequencial Chemoradiotherapy with or Without Toripalimab (PD-1 Antibody) in Newly Diagnosed Early-Stage Extranodal Natural Killer/T Cell Lymphoma, Nasal Type (ENKTL)RecruitingPhase 3Sun Yat-sen UniversityNCT04365036Written as Pegaspargase
- Blinatumomab Plus Venetoclax Sequenced With Inotuzumab Ozogamicin in Treating B-ALLRecruitingPhase 2First Affiliated Hospital of Zhejiang UniversityNCT06554626Written as Pegaspargase
- Ma-Spore ALL 2020 StudyRecruitingPhase 2National University Hospital, SingaporeNCT06336395Written as Pegylated asparaginase
- PEG-ASP, Etoposide and Gemcitabine for Natural Killer/T LymphomaRecruitingPhase 2Sun Yat-sen UniversityNCT02705508Written as Pegaspargase
- Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic LymphomaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT02112916Written as Pegaspargase
- Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and NavitoclaxActive, not recruitingPhase 1/2St. Jude Children's Research HospitalNCT05192889Written as Pegaspargase
- Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaActive, not recruitingPhase 3Children's Oncology GroupNCT03007147Written as Pegaspargase
- A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic LeukemiaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT03914625Written as Pegaspargase
Showing 20 of 72.
As the comparator · 3 — what is tested is compared with pegaspargase
- Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)CompletedPhase 3AmgenNCT02393859Written as PEG-asparaginase
- A Study of PD5K3 in Healthy Adult VolunteersCompletedPhase 1Chongqing Peg-Bio Biopharm Co., Ltd.NCT06527781Written as Pegaspargase
- Trial of Oncaspar® and Three Doses of Pegylated Recombinant Asparaginase in Adult Patients With Newly Diagnosed Acute Lymphoblastic LeukaemiaTerminatedPhase 1/2medac GmbHNCT01251809Written as Oncaspar
Codes
What other systems call pegaspargase · ClinicalTrials.gg INT003165
- MeSH (NLM) C042705pegaspargaseConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 7D96IR0PPMPEGASPARGASEConfirmed FDA, NLM, Wikidata
- RxNorm 34132Confirmed FDA, Wikidata
- Wikidata Q7160547pegaspargaseConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1200PegaspargaseOne source FDA
- DrugBank DB00059One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C042705 | pegaspargase | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 7D96IR0PPM | PEGASPARGASE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 34132 | — | Confirmed FDA, Wikidata |
| Wikidata | Q7160547 | pegaspargase | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1200 | Pegaspargase | One source FDA |
| DrugBank | DB00059 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.