Neurotransmitter Agents clinical trials
A class of medicines: the studies that test any of its 4 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones.
Get an email when these change. Save the neurotransmitter agents studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Medicines in this class
Studies that test each. A study of two counts under both, and once above.
- Met-enkephalin
- 2
Studies by the year they started
157 studies that test it; most in 2020 (12)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1998 | 2 |
| 1999 | 1 |
| 2000 | 2 |
| 2001 | 3 |
| 2002 | 3 |
| 2003 | 1 |
| 2004 | 4 |
| 2005 | 8 |
| 2006 | 5 |
| 2007 | 2 |
| 2008 | 5 |
| 2009 | 7 |
| 2010 | 4 |
| 2011 | 8 |
| 2012 | 7 |
| 2013 | 5 |
| 2014 | 3 |
| 2015 | 6 |
| 2016 | 10 |
| 2017 | 9 |
| 2018 | 6 |
| 2019 | 7 |
| 2020 | 12 |
| 2021 | 6 |
| 2022 | 4 |
| 2023 | 9 |
| 2024 | 7 |
| 2025 | 4 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 47 · Other 110
Mallinckrodt (15) · Massachusetts General Hospital (9) · Danish Headache Center (8) · Bellerophon Pulse Technologies (6) · Tomsk National Research Medical Center of the Russian Academy of Sciences (5) · Sanotize Research and Development corp. (5) · Beyond Air Inc. (5) · Wake Forest University Health Sciences (4)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing one of them · 157
- NO During CPB in Neonates to Reduce Risk of AKIRecruitingPhase 3Children's Hospital Medical Center, CincinnatiNCT04216927Written as Nitric Oxide
- The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPDNot yet recruitingPhase 1/2University of AlbertaNCT04231760Written as Inhaled Nitric Oxide
- Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain InjuryEnrolling by invitationPhase 2University of PennsylvaniaNCT05616910Written as inhaled nitric oxide
- Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary BypassRecruitingPhase 3Xijing HospitalNCT06702553Written as Nitric Oxide Gas
- iNO300 Therapy in Critically Ill Patients With PneumoniaRecruitingEarly Phase 1Massachusetts General HospitalNCT06950294Written as High dose inhaled nitric oxide
- Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical ThrombectomyRecruitingPhase 1Wake Forest University Health SciencesNCT05871606Written as iNO
- Inhaled Nitric Oxide for Prevention of Postoperative AKI in High-Risk Cardiac Surgery PatientsNot yet recruitingNot applicableShanghai Zhongshan HospitalNCT07544147Written as Inhaled Nitric Oxide (iNO)
- Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activating Polypeptide-38Not yet recruitingNot applicableDanish Headache CenterNCT07342296Written as Pituitary Adenylate Cyclase Activating Polypeptide-38 (PACAP-38)
- Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic HerniaNot yet recruitingPhase 4Asan Medical CenterNCT07247240Written as Inhaled Nitric Oxide
- Substance P-Induced Migraine Attacks Without AuraRecruitingNot applicableDanish Headache CenterNCT06959004Written as Substance P
- Effects of Substance P on Headache Induction in Healthy IndividualsNot yet recruitingNot applicableDanish Headache CenterNCT06632080Written as Substance P
- Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).RecruitingEarly Phase 1Dr. Denis O'DonnellNCT05052229Written as Nitric Oxide
- Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular FunctionRecruitingNot applicableFernando Suarez SipmannNCT06097026Written as Nitric Oxide
- Inhaled Nitric Oxide for ARDS-related Pulmonary HypertensionNot yet recruitingEarly Phase 1Yuri MatusovNCT06249633Written as Nitric Oxide
- The Effects of a Nitrate Supplementation on Erectile FunctionRecruitingNot applicableRHA Investments LtdNCT06213077Written as Nitric Oxide
- Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney DiseaseCompletedPhase 1/2Tomsk National Research Medical Center of the Russian Academy of SciencesNCT05757557Written as 80-ppm NO
- Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac SurgeryCompletedPhase 1/2Nikolay KamenshchikovNCT03527381Written as Nitric Oxide
- Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary BypassCompletedPhase 1/2Tomsk National Research Medical Center of the Russian Academy of SciencesNCT03500783Written as Nitric Oxide
- High-dose Inhalations of Nitric Oxide in the Treatment of PneumoniaActive, not recruitingNot applicableTomsk National Research Medical Center of the Russian Academy of SciencesNCT06170372Written as 200 ppm Nitric Oxide
- High-dose Inhaled NO Therapy for the Prevention of Nosocomial Pneumonia After Cardiac Surgery With CPBCompletedNot applicableTomsk National Research Medical Center of the Russian Academy of SciencesNCT06162455Written as 200- ppm NO
See all 157 studies that test one of the neurotransmitter agents →