Neurotransmitter Agents: all 157 studies that test it

Page 1 of 2. Open to participants first (15), then studies with results posted, then the rest; newest registration first within each.

• Inhaled Nitric Oxide for Prevention of Postoperative AKI in High-Risk Cardiac Surgery PatientsNot yet recruitingNCT07544147Not applicable
• Induction of Migraine Attacks With Aura Using Pituitary Adenylate Cyclase Activating Polypeptide-38Not yet recruitingNCT07342296Not applicable
• Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic HerniaNot yet recruitingNCT07247240Phase 4
• Substance P-Induced Migraine Attacks Without AuraRecruitingNCT06959004Not applicable
• iNO300 Therapy in Critically Ill Patients With PneumoniaRecruitingNCT06950294Early Phase 1
• Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary BypassRecruitingNCT06702553Phase 3
• Effects of Substance P on Headache Induction in Healthy IndividualsNot yet recruitingNCT06632080Not applicable
• Inhaled Nitric Oxide for ARDS-related Pulmonary HypertensionNot yet recruitingNCT06249633Early Phase 1
• The Effects of a Nitrate Supplementation on Erectile FunctionRecruitingNCT06213077Not applicable
• Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular FunctionRecruitingNCT06097026Not applicable
• Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical ThrombectomyRecruitingNCT05871606Phase 1
• Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain InjuryEnrolling by invitationNCT05616910Phase 2
• Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).RecruitingNCT05052229Early Phase 1
• The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPDNot yet recruitingNCT04231760Phase 1/2
• NO During CPB in Neonates to Reduce Risk of AKIRecruitingNCT04216927Phase 3
• Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 InfectionTerminatedNCT05109611Phase 3Results posted
• Substance P Challenge in Healthy ParticipantsCompletedNCT04676763Not applicableResults posted
• A Study to Assess Pulsed Inhaled Nitric Oxide vs Placebo in Subjects With Mild or Moderate COVID-19TerminatedNCT04421508Phase 3Results posted
• Inhaled Nitric Oxide for Preventing Progression in COVID-19TerminatedNCT04388683Phase 2Results posted
• Nitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19CompletedNCT04306393Phase 2Results posted
• Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19TerminatedNCT04305457Phase 2Results posted
• Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary DysplasiaTerminatedNCT03576885Phase 1/2Results posted
• Nitric Oxide Administration During Pediatric Cardiopulmonary Bypass Surgery to Prevent Platelet ActivationCompletedNCT03455218Phase 2/3Results posted
• Inhaled Nitric Oxide in Brain InjuryCompletedNCT03260569Phase 3Results posted
• Inhaled Selective Pulmonary Vasodilators for Advanced Heart Failure Therapies and Lung Transplantation OutcomesCompletedNCT03081052Phase 4Results posted
• Inhaled Nitric Oxide After Out-of-Hospital Cardiac ArrestTerminatedNCT03079102Phase 2Results posted
• Nitric Oxide Releasing Solution (NORS) Footbath to Treat Athlete's FootCompletedNCT02871011Phase 2Results posted
• Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.CompletedNCT02836899Phase 3Results posted
• Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAHCompletedNCT02734953Phase 2Results posted
• Clinical Study of Pulsed, Inhaled Nitric Oxide Versus Placebo in Symptomatic Subjects With PAHTerminatedNCT02725372Phase 3Results posted
• Efficacy of Nitric Oxide Administration in Attenuating Ischemia/Reperfusion Injury During Neonatal Cardiopulmonary BypassCompletedNCT02151877Not applicableResults posted
• Nitric Oxide to Treat Pulmonary EmbolismCompletedNCT01939301Phase 2Results posted
• Study of Inhaled Nitric Oxide (iNO) and Respiratory Outcomes in Late Preterm InfantsTerminatedNCT01748045Phase 2/3Results posted
• Inhaled Nitric Oxide and Inhaled Prostacyclin After Cardiac Surgery for Heart Transplant or LVAD PlacementCompletedNCT01717209Phase 4Results posted
• Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal ResuscitationCompletedNCT01220687Not applicableResults posted
• Nitric Oxide, GeNO Nitrosyl Delivery SystemCompletedNCT01165047Phase 2Results posted
• Examining the Use of Non-Invasive Inhaled Nitric Oxide to Reduce Chronic Lung Disease in Premature NewbornsCompletedNCT00955487Phase 2Results posted
• Effect of Nitric Oxide (NO) on Ischemic/Reperfusion Injury During Extended Donor Criteria (EDC) Liver TransplantationTerminatedNCT00948194Not applicableResults posted
• The Effects of Inhaled Nitric Oxide After Fontan OperationCompletedNCT00945529Phase 2/3Results posted
• Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm InfantsCompletedNCT00931632Phase 3Results posted
• Topical Nitric Oxide Trial in Chronic Non-Healing WoundsTerminatedNCT00823095Phase 2Results posted
• Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator TestingCompletedNCT00626028Phase 3Results posted
• Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in SepsisCompletedNCT00608322Phase 3Results posted
• Inhaled NO as an Anti-inflammatory and Anti-reperfusion Agent in Infants and Children Undergoing Cardiopulmonary BypassCompletedNCT00585013Phase 1/2Results posted
• Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After TransplantationCompletedNCT00582010Phase 2/3Results posted
• Safety and Tolerability of Inhaled Nitric Oxide in Patients With Cystic FibrosisCompletedNCT00570349Phase 1/2Results posted
• Nitric Oxide in Myocardial Infarction SizeTerminatedNCT00568061Phase 2Results posted
• Safety and Efficacy Study of Nitric Oxide for Inhalation on Chronic Lung Disease in Premature BabiesCompletedNCT00551642Phase 3Results posted
• Nitric Oxide Administration for Acute Respiratory Distress SyndromeCompletedNCT00240487Phase 3Results posted
• Nitric Oxide Inhalation to Treat Sickle Cell Pain CrisesCompletedNCT00094887Phase 2Results posted
• The Effects of Nitric Oxide for Inhalation During Left Ventricular Assists Device (LVAD) ImplantationCompletedNCT00060840Phase 2Results posted
• Perioperative Nitric Oxide Prevents Acute Kidney Injury in Acute Type A Aortic Dissection PatientsCompletedNCT06622291Phase 4
• High-dose Inhaled NO Therapy for the pREvenvention of NP After Cardiac Surgery Under CPBCompletedNCT06261827Not applicable
• High-dose Inhalations of Nitric Oxide in the Treatment of PneumoniaActive, not recruitingNCT06170372Not applicable
• High-dose Inhaled NO Therapy for the Prevention of Nosocomial Pneumonia After Cardiac Surgery With CPBCompletedNCT06162455Not applicable
• Nitric Oxide Releasing Mouthwash (NORM) for the Management of Oropharyngeal CandidiasisCompletedNCT06120816Phase 1
• Nitric Oxide Releasing Solution (NORS) For The Treatment Of Human Papillomavirus(HPV) Verrucae Plantaris (Plantar Warts)CompletedNCT05877313Phase 2
• Inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA)Status unknownNCT05868109Phase 2
• Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney DiseaseCompletedNCT05757557Phase 1/2
• A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Hypertension Associated With Pulmonary FibrosisStatus unknownNCT05747508Phase 2
• Inhaled NO in Surgical Patients With Recent COVID-19 InfectionCompletedNCT05721144Phase 2
• Methemoglobin Concentration in High Dose Inhaled Nitric OxideActive, not recruitingNCT05612074Early Phase 1
• Nitric Oxide Nasal Spray (NONS) To Treat and Prevent the Exacerbation of Infection in Individuals With Mild COVID-19CompletedNCT05599919Phase 3
• Consistency of Electrical Cardiometry and Pulmonary Artery CatheterStatus unknownNCT05587400Not applicable
• Hypersensitivity to PACAP-38 in Post-Traumatic HeadacheStatus unknownNCT05378061Not applicable
• Effect of iNO in Patients With Submassive and Massive PEWithdrawnNCT04996667Phase 2
• Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Intractable Cerebral VasospasmCompletedNCT04988932Not applicable
• The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy VolunteersCompletedNCT04960657Not applicable
• Inhaled Nitric Oxide (iNO) in Post-Pulmonary Embolism (Post-PE)CompletedNCT04920695Not applicable
• Nitric Oxide During Cardiopulmonary Bypass in Adult SurgeryStatus unknownNCT04807413Phase 3
• iNOPulse for COVID-19WithdrawnNCT04398290Phase 2
• High Dose Inhaled Nitric Oxide for COVID-19 (ICU Patients)CompletedNCT04383002Phase 1
• Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 InfectionCompletedNCT04374032Phase 2/3
• Nitric Oxide Inhalation Therapy for COVID-19 Infections in the EDTerminatedNCT04338828Phase 2
• Nitric Oxide Gas Inhalation for Severe Acute Respiratory Syndrome in COVID-19.WithdrawnNCT04290871Phase 2
• Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID19 InfectionWithdrawnNCT04290858Phase 2
• The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in HypoxiaCompletedNCT04231773Phase 1/2
• The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in Interstitial Lung Disease.WithdrawnNCT04181359Phase 1/2
• Nitric Oxide Releasing Sinus Irrigation (NOSi) to Treat Recalcitrant Chronic Rhinosinusitis (RCRS)CompletedNCT04163978Phase 2
• Improving Outcomes in Cardiac Arrest With Inhaled Nitric OxideStatus unknownNCT04134078Early Phase 1
• The Effect of Inhaled Nitric Oxide on Deadspace in COPDCompletedNCT04069052Early Phase 1
• Evaluation of Two Doses of Nitric Oxide (NO) Given Intermittently Via Inhalation to Subjects With BronchiolitisCompletedNCT04060979Phase 2
• Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical PatientsWithdrawnNCT04022161Phase 2
• Inhaled NO in IPF and COPD During 6 Minute Walk TestStatus unknownNCT03873298Phase 2
• Effects of Nitric Oxide on the Endothelium During Hemolysis.WithdrawnNCT03748082Phase 2
• A Dose Escalation Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis or SarcoidosisCompletedNCT03727451Phase 2
• The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in COPDCompletedNCT03679312Phase 1/2
• Nitric Oxide During Bypass for Arterial Switch OperationCompletedNCT03661385Phase 3
• Study of PAH Subjects With LTOT Use That Have Demonstrated Improved Exercise Tolerance With the Use of Inhaled NitricWithdrawnNCT03602781Phase 3
• Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac SurgeryCompletedNCT03527381Phase 1/2
• Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary BypassCompletedNCT03500783Phase 1/2
• PACAP27 Headache Properties in Migraine Without Aura PatientsCompletedNCT03471039Not applicable
• Inhaled Gaseous Nitric Oxide (gNO) Antimicrobial Treatment of Difficult Bacterial and Viral Lung (COVID-19) InfectionsTerminatedNCT03331445Phase 2
• A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis at Risk for Pulmonary HypertensionTerminatedNCT03267108Phase 3
• Inhaled Nitric Oxide for Patients With MABSCCompletedNCT03208764Phase 2
• Effect iNO on Functional Respiratory Imaging in Subjects With WHO Group 3 Pulmonary Hypertension With COPD on OxygenTerminatedNCT03135860Early Phase 1
• Evaluation of the Efficacy Safety and Tolerability of Nitric Oxide Given Intermittently Via Inhalation to Subjects With BronchiolitisCompletedNCT03053388Phase 3
• Diffuse Optical Monitoring With Inhaled Nitric OxideActive, not recruitingNCT03023449Phase 2
• Salvage Treatment of Inhaled Nitric Oxide in Patients With Refractory Hypoxemia After Aortic SurgeryStatus unknownNCT03009643Not applicable
• Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNOStatus unknownNCT02851472Phase 1/2

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