Mitomycin: all 137 studies that test it

Page 1 of 2. Open to participants first (23), then studies with results posted, then the rest; newest registration first within each.

• Metronomic Gemcitabine, Mitomycin C, and Thalidomide for Advanced Solid TumorsRecruitingNCT07671534Phase 2
• Disitamab Vedotin Plus Intravesical Mitomycin C in HER2-Expressing Intermediate- to High-Risk Non-Muscle-Invasive Bladder CancerRecruitingNCT07646145Phase 2
• Safety and Efficacy of PIPAC Using Single Agent Mitomycin in Solid TumorsRecruitingNCT07487168Phase 1
• Combined Systemic and Intraperitoneal Chemotherapy for Synchronous Gastric and/or Gastroesophageal Peritoneal CarcinomatosisRecruitingNCT07475286Phase 2
• Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT TrialRecruitingNCT07271355Phase 3
• Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 StudyNot yet recruitingNCT07189793Phase 2
• Efficacy of the Use of Neoadjuvant With/Without Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Colon CancerRecruitingNCT06783491Phase 3
• Chemoablation Or Bladder Resection With Adjuvant Chemotherapy in Recurrent Non-Muscle Invasive Bladder CancerRecruitingNCT06781879Phase 4
• In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE TrialRecruitingNCT06704191Phase 1/2
• Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC PatientsRecruitingNCT06696794Phase 3
• Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation SurgeryNot yet recruitingNCT06680245Phase 3
• Study to Evaluate the Non-inferiority of Low-dose HIPEC Versus High-dose HIPEC in the Treatment of PMP (HIPEC-PMP)RecruitingNCT06513065Phase 3
• The Clinical Effectiveness and Safety of Intravesical Mitomycin-C and Gemcitabine Sequential TherapyRecruitingNCT06388720Phase 2
• Precise Chemoresection in Low-grade NMIBC Using Drug Screens in Patient-derived OrganoidsNot yet recruitingNCT06227065Phase 2
• POST URS Chemotherapy InstillationRecruitingNCT06167057Not applicable
• Intravesical Mitomycin C After Diagnostic Ureteroscopy for Upper Tract Urothelial CarcinomaNot yet recruitingNCT05979909Phase 1
• Adaptive Radiation in Anal CancerRecruitingNCT05838391Not applicable
• Phase II Trial of Lung ChemoemobolizationRecruitingNCT05672108Phase 2
• Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingNCT04847063Phase 1
• Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal ChemotherapyNot yet recruitingNCT04845490Phase 2
• PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric CancerRecruitingNCT04329494Phase 1
• Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric CancerRecruitingNCT04107077Phase 2
• Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.RecruitingNCT03914820Not applicable
• A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder CancerActive, not recruitingNCT05243550Phase 3Results posted
• Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)CompletedNCT05136898Phase 3Results posted
• A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder CancerTerminatedNCT04688931Phase 3Results posted
• Subconjunctival Versus Direct Mitomycin C in TrabeculectomyCompletedNCT04352660Phase 4Results posted
• Comparing Preoperative Injection of Mitomycin-C vs. Intraoperative Injection of Mitomycin-C vs. Topical Application of Mitomycin-C (Conventional Use) in TrabeculectomyTerminatedNCT03875911Phase 4Results posted
• Trial of Mitomycin C During Nephroureterectomy for Urothelial CarcinomaCompletedNCT03658304Phase 2Results posted
• Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder CancerCompletedNCT03617913Phase 2Results posted
• A Phase 2b Study of UGN-102 for Low Grade Intermediate Risk Non-Muscle-Invasive Bladder CancerCompletedNCT03558503Phase 2Results posted
• Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal CytologyCompletedNCT03092518Phase 2Results posted
• Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal CancerCompletedNCT02891447Phase 2Results posted
• Ahmed Glaucoma Valve Surgery With Mitomycin-CCompletedNCT02805257Phase 2Results posted
• The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC StudyCompletedNCT02793128Phase 3Results posted
• The Bladder Instillation Comparison StudyCompletedNCT02695771Phase 3Results posted
• Mitomycin C in Patients With Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Standard TherapiesCompletedNCT02369458Phase 2Results posted
• CAVATAK (CVA21) in Non-muscle Invasive Bladder Cancer (VLA-012 CANON)CompletedNCT02316171Phase 1Results posted
• Laparoscopic Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) for Metastatic Gastric CancerCompletedNCT02092298Phase 2Results posted
• HIPEC for Peritoneal CarcinomatosisCompletedNCT02040142Phase 2Results posted
• Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal CarcinomaCompletedNCT01858025Early Phase 1Results posted
• A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal CancerTerminatedNCT01671488Phase 1/2Results posted
• Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the AppendixCompletedNCT01580410Phase 2Results posted
• Study of Mitomycin-C Application in Laryngotracheal StenosisTerminatedNCT01523275Not applicableResults posted
• Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal CancerTerminatedNCT01324141Phase 1Results posted
• Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic CancerCompletedNCT01296763Phase 1Results posted
• Radiation Therapy and Chemotherapy in Treating Patients With Stage I Bladder CancerCompletedNCT00981656Phase 2Results posted
• Mitomycin C Versus Bacillus Calmette-Guerin in the Intravesical Treatment of Non-Muscle-Invasive Bladder Cancer PatientsTerminatedNCT00974818Phase 3Results posted
• Mitomycin C With Hyperthermia and Intravesical Mitomycin C to Treat Recurrent Bladder CancerCompletedNCT00734994Early Phase 1Results posted
• Primary Tube Versus Trabeculectomy StudyCompletedNCT00666237Phase 4Results posted
• Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal CancerCompletedNCT00423293Phase 2Results posted
• Safety Study of Recombinant Human Hyaluronidase (Chemophase) in Combination With Mitomycin in Participants With Superficial Bladder CancerCompletedNCT00318643Phase 1/2Results posted
• Trial of Adjuvant Chemotherapy for Gastric CancerCompletedNCT00296335Phase 3Results posted
• Trial of Adjuvant Chemotherapy for Gastric CancerCompletedNCT00296322Phase 3Results posted
• Individualized Drug Treatment for Treating Patients With Pancreatic CancerTerminatedNCT00276744Phase 2Results posted
• A Study of Mitomycin C, Irinotecan, and CetuximabTerminatedNCT00271011Phase 2Results posted
• A Phase II Study of Intra-arterial Chemotherapy With Cisplatin and Mitomycin-C in Patients With Hepatocellular CarcinomaCompletedNCT00183885Phase 2Results posted
• Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the LiverCompletedNCT00003907Phase 2Results posted
• Bladder Preservation or Cystectomy for MIBCActive, not recruitingNCT07821177Early Phase 1
• BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder CancerActive, not recruitingNCT06462001Phase 3
• Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral StrictureCompletedNCT06232005Phase 2/3
• REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity MitigationActive, not recruitingNCT05902533Phase 2/3
• Comparison Between Topical Mitomycin C and CyclosporineCompletedNCT05627947Phase 1
• Guiding Instillation in Non Muscle-invasive Bladder Cancer Based on Drug Screens in Patient Derived OrganoidsActive, not recruitingNCT05024734Phase 2
• Therapy Adapted for High Risk and Low Risk HIV-Associated Anal CancerActive, not recruitingNCT04929028Phase 2
• Conjunctival Vascularity Changes Usnig OCTA After TrabeculectomyStatus unknownNCT04493073Early Phase 1
• A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE TrialActive, not recruitingNCT04216290Phase 2
• Chemoembolization for Lung TumorsCompletedNCT04200417Phase 1
• Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE StudyActive, not recruitingNCT04166318Phase 2
• Efficacy of Topical Mitomycin C for Complex Benign Esophageal Anastomotic StricturesWithdrawnNCT04037072Phase 2
• Efficacy and Safety of UGN-101 in Recurrent PatientsWithdrawnNCT04006691Phase 3
• Sequential Combination Therapy in Bladder CancerStatus unknownNCT03790384Phase 4
• Study of IMRT Radiotherapy Concurrent Chemothrerapy for Anal CancerStatus unknownNCT03381352Phase 2
• Neoadjuvant Short-term Intensive Chemoresection Versus Standard Adjuvant Intravesical Instillations in NMIBCCompletedNCT03348969Phase 4
• Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive CytologyCompletedNCT03330028Phase 1
• A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin CStatus unknownNCT03242317Phase 4
• A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before ImplantationStatus unknownNCT03126877Phase 4
• A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated With Mitomycin C Following Femtosecond Flap Creation.TerminatedNCT03101501Phase 4
• Surgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-CaribbeansStatus unknownNCT02989207Not applicable
• Adding Mitomycin to BCG as Adjuvant Intravesical Therapy for High-risk Non-Muscle-invasive Bladder CancerActive, not recruitingNCT02948543Phase 3
• Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled GlaucomaCompletedNCT02901236Phase 2/3
• Mitomycin C Trabeculectomy Trial for Glaucoma in EthiopiaWithdrawnNCT02744690Not applicable
• Risk Enabled Therapy After Initiating Neoadjuvant Chemotherapy for Bladder Cancer (RETAIN)CompletedNCT02710734Phase 2
• Pterygium Head Body MMC1: Two Different Surgical Procedures and Their Effect on Endothelial Cell Count.Status unknownNCT02641132Phase 4
• Clinical Trial to Evaluate Safety and Efficacy of Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) With Mitomycin C Used During Surgery for Treatment of Locally Advanced Colorectal CarcinomaStatus unknownNCT02614534Phase 3
• Bleb Function and Morphology With Intratendon Injection of MMC Compared With Standard MethodStatus unknownNCT02385370Phase 3
• Phase I Mitomycin Combined With Bacillus Calmette-Guérin (BCG) for Bladder CancerCompletedNCT02311101Phase 1
• Safety of Pre-TURBT Intravesical Instillation of Escalating Doses of TC-3 Gel and MMC in NMIBC PatientsCompletedNCT02307487Phase 2
• Study of Interventional Pulmonologic Treatment of Benign Central Airway Fibrotic StrictureStatus unknownNCT02287389Not applicable
• Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial NeoplasiaCompletedNCT02199327Phase 4
• Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic RhinosinusitisCompletedNCT02106793Phase 3
• Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder CancerStatus unknownNCT02070120Phase 2
• The Use of MMC During PRK and Its Effect on Postoperative Topical Steroid RequirementsStatus unknownNCT02030990Phase 2/3
• Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and NeckTerminatedNCT02015650Phase 4
• The Efficacy of 5-fluorouracil/Mitomycin for the Patients With Pulmonary Metastasis of Hepatocellular CarcinomaWithdrawnNCT01953406Phase 2
• Intravesical Adjuvant Electromotive Mitomycin-CCompletedNCT01920269Phase 2/3
• Phase II Study of Concomitant Intensity-modulated Radiotherapy Combined to Capecitabine, Mitomycin and Panitumumab in Patients With Stage II-IIIB Squamous-cell Carcinoma of the Anal CanalTerminatedNCT01843452Phase 2
• ICARuS Post-operative Intraperitoneal Chemotherapy (EPIC) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) After Optimal Cytoreductive Surgery (CRS) for Neoplasms of the Appendix, Colon or Rectum With Isolated Peritoneal MetastasisActive, not recruitingNCT01815359Phase 2
• Mitomycin C Therapy for Patients With Primary Sclerosing CholangitisStatus unknownNCT01688024Phase 2
• Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0CompletedNCT01621217Phase 1

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