Drug
Mefloquine clinical trials
Also written Lariam.
- studies test it
- 30
- open now
- 0
- in phase 3
- 10
- first study started
- 1998
How studies write it
Studies that test it under each name
Name
Brand
Studies by the year they started
30 studies that test it; most in 2005 (4)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 2004 | 1 |
| 2005 | 4 |
| 2006 | 1 |
| 2007 | 3 |
| 2008 | 1 |
| 2009 | 2 |
| 2010 | 4 |
| 2011 | 2 |
| 2012 | 1 |
| 2013 | 2 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 1 |
| 2019 | 2 |
| 2020 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 9
- Phase 3
- 10
- Phase 4
- 6
- No phase
- 6
What it is tested for
Each study’s main condition, where its own words name it.
- Malaria
- 17
Who runs them
Industry 4 · Other 26
University of Oxford (3) · Institute of Tropical Medicine, Belgium (3) · London School of Hygiene and Tropical Medicine (3) · Armed Forces Research Institute of Medical Sciences, Thailand (3) · U.S. Army Medical Research and Development Command (2) · Albert Schweitzer Hospital (2) · Pfizer (2) · Instituto Nacional de Salud. Peru (1)
Often tested with
Tested in the same studies.
Artesunate (12) · Fanasil, pyrimethamine drug combination (4) · Azithromycin (3) · Chloroquine (3) · Artenimol (2) · Piperaquine (2) · Hydroxychloroquine (1) · Tocilizumab (1)
Studies
Open first, then newest update. How each study uses Mefloquine is read from its arms, and is right about nine times in ten.
Testing it · 30
- Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation TherapyTerminatedPhase 1M.D. Anderson Cancer CenterNCT01430351Written as Mefloquine
- Safety and Efficacy of NF135 CPS ImmunizationTerminatedNot applicableRadboud University Medical CenterNCT03813108Written as CPS-immunization
- Randomised Trial of 3 Artemisinin Combination Therapy for Malaria in PregnancyCompletedPhase 3University of OxfordNCT01054248Written as Artesunate-mefloquine
- Assessment of Artesunate/Mefloquine in the Peruvian AmazonCompletedPhase 4Instituto Nacional de Salud. PeruNCT02084602Written as Mefloquine
- Merozoite Surface Protein 1 Antibody Response in Asymptomatic Human Malaria InfectionCompletedNot applicableU.S. Army Medical Research and Development CommandNCT00761020Written as Mefloquine
- Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African ChildrenCompletedPhase 3Institute of Tropical Medicine, BelgiumNCT03893097Written as Artesunate + Mefloquine
- Malaria Elimination Pilot Study in Military Forces in CambodiaStatus unknownPhase 4Armed Forces Research Institute of Medical Sciences, ThailandNCT02653898Written as Artesunate + Mefloquine
- A Study of the Effectiveness of an Off Label Mefloquine Use for the Treatment of Patients With COVID19CompletedPhase 2/3Burnasyan Federal Medical Biophysical CenterNCT04347031Written as Mefloquine
- Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in CambodiaCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT02612545Written as Mefloquine (MQ)
- A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium FalciparumCompletedPhase 2U.S. Army Medical Research and Development CommandNCT02488902Written as Mefloquine 250 mg
- Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western CambodiaWithdrawnPhase 2/3University of OxfordNCT00936767Written as Artemisone/Mefloquine (AmiM3)
- A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + PatientsCompletedPhase 1ORIYOMI OMOTOYOSI AKINYOTUNCT02524444Written as Mefloquine
- In Vivo and In Vitro Efficacy of Artemisinin Combination TherapyCompletedPhase 4Global Emerging Infections Surveillance and Response SystemNCT01976780Written as Mefloquine
- The Effect of Malaria on Disease Progression of HIV/AIDSCompletedNot applicableLondon School of Hygiene and Tropical MedicineNCT00499876Written as mefloquine
- Kilimanjaro IPTi Drug Options TrialCompletedPhase 2/3London School of Hygiene and Tropical MedicineNCT00158574Written as mefloquine
- Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With MalariaCompletedPhase 3Institute of Tropical Medicine, BelgiumNCT00852423Written as Artesunate-mefloquine
- Harmonized AS/MQ Efficacy Study - ThailandCompletedPhase 4Armed Forces Research Institute of Medical Sciences, ThailandNCT02052323Written as Artesunate/mefloquine (AS/MQ)
- Pharmacokinetic and Pharmacodynamic Study of Mefloquine and Dihydroartemisinin-Piperaquine in Healthy SubjectsCompletedPhase 4University of OxfordNCT02324738Written as Mefloquine
- P. Knowlesi Trial of Artesunate-mefloquine Versus ChloroquineCompletedPhase 3Menzies School of Health ResearchNCT01708876Written as Artesunate-mefloquine
- Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML)TerminatedPhase 1/2BiogenNCT00746941Written as mefloquine
See all 30 studies that test Mefloquine →
Given in every arm · 1 — Mefloquine is usual care beside what is tested
As the comparator · 7 — what is tested is compared with Mefloquine
- Compare the Effectiveness Between Existing Treatment and New TreatmentTerminatedNot applicableUniversity of OxfordNCT01640587Written as Mefloquine+Artesunate
- Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria PatientsCompletedPhase 3Medicines for Malaria VentureNCT00403260Written as Mefloquine plus artesunate
- Clinical Investigation of In-vivo Susceptibility of P.Falciparum to Artesunate in Western CambodiaCompletedNot applicableUniversity of OxfordNCT00493363Written as Artesunate + Mefloquine
- An Evaluation of Weekly TafenoquineCompletedPhase 2U.S. Army Medical Research and Development CommandNCT02488980Written as Mefloquine
- Prevention of Pregnancy-associated Malaria in HIV-infected Women: Cotrimoxazole Prophylaxis Versus MefloquineCompletedPhase 3Institut de Recherche pour le DeveloppementNCT00970879Written as mefloquine
- Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory FunctionCompletedPhase 4NovartisNCT00444106Written as Artesunate-mefloquine
- Efficacy and Safety of Dihydroartemisinin/Piperaquine (Artekin®) for the Treatment of Uncomplicated Malaria in PeruCompletedPhase 3Institute of Tropical Medicine, BelgiumNCT00373607Written as Mefloquine + Artesunate
Codes
What other systems call Mefloquine · ClinicalTrials.gg INT008498
- MeSH (NLM) D015767MefloquineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) TML814419RMEFLOQUINEConfirmed FDA, NLM, Wikidata
- RxNorm 6694Confirmed FDA, Wikidata
- Wikidata Q27084116(-)-mefloquineConfirmed FDA, NLM, Wikidata
- Wikidata Q72488310Mefloquine hydrochlorideConfirmed FDA, NLM, Wikidata
- Wikidata Q736270mefloquineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61827MefloquineOne source FDA
- DrugBank DB00358One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015767 | Mefloquine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | TML814419R | MEFLOQUINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6694 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27084116 | (-)-mefloquine | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q72488310 | Mefloquine hydrochloride | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q736270 | mefloquine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61827 | Mefloquine | One source FDA |
| DrugBank | DB00358 | — | One source Wikidata |
Also registered as mefloquine hydrochloride (UNII 5Y9L3636O3 · RxNorm 82130).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.