Schistosomiasis clinical trials
The registry lists 79 studies for Schistosomiasis across more than 10 countries. 14 are recruiting or about to start. 55 of them are mainly about Schistosomiasis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its narrower condition Schistosomiasis haematobia too: 93 studies, 16 open.
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Who runs them
DBL -Institute for Health Research and Development (9) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · Leiden University Medical Center (5) · Centre de Recherche Médicale de Lambaréné (3) · IRCCS Sacro Cuore Don Calabria di Negrar (3) · Oswaldo Cruz Foundation (3) · Assistance Publique - Hôpitaux de Paris (2) · London School of Hygiene and Tropical Medicine (2)
What is being tested here
Drugs under test in Schistosomiasis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Jan 2027Assessment of Infection Activity in Travelers and Migrants Diagnosed With Chronic Schistosomiasis · IRCCS Sacro Cuore Don Calabria di Negrar
- Mar 2027Long-Term Outcomes of Selexipag in Schistosomiasis-Associated Pulmonary Arterial Hypertension · Caio Júlio César dos Santos Fernandes
- Jul 2027Assessment of Right Ventricular-Pulmonary Arterial Coupling in Schistosomiasis-Associated Pulmonary Arterial Hypertension · Sohag University
- Jul 2027Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations · Uwemedimo Friday Ekpo
- Aug 2027Prevalence and Molecular Identification of Human Schistosomiasis · Assiut University
- Aug 2027MATCHING - feMAle geniTal sCHistosomiasis IN miGrants Female Genital Schistosomiasis in Migrants Presenting to an Outpatient Clinic in Italy: Prevalence and Clinical Impact · IRCCS Sacro Cuore Don Calabria di Negrar
Who these studies take
Of the 6 Schistosomiasis studies recruiting now, 3 (50%) set no upper age limit and 3 (50%) stop at 75 or younger. 6 (100%) take children under 18. 1 (17%) are for women only and 0 (0%) for men only; 3 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (67%) | 4 (67%) |
| 18 | 5 (83%) | 4 (67%) |
| 30 | 5 (83%) | 4 (67%) |
| 40 | 5 (83%) | 4 (67%) |
| 50 | 4 (67%) | 4 (67%) |
| 65 | 4 (67%) | 4 (67%) |
| 75 | 4 (67%) | 4 (67%) |
| 85 | 3 (50%) | 3 (50%) |
Across all 79 studies, recruiting or not: 70% stop at 75 or younger and 68% at 65; 68% take children; 14% are for women only and 3% for men only; 61% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 79. Browse all 79 → or search them.
- A Phase III Trial to Evaluate the Safety and Efficacy of Anti-inflammatory Drugs in Addition to Praziquantel in Girls and Women With Female Genital SchistosomiasisNot yet recruitingNCT07915518Phase 34 countries
- Different Treatment Frequencies for Hepatic Fibrosis Due to SchistosomiasisNot yet recruitingNCT07754617Phase 2/31 country
- Assessment of Right Ventricular-Pulmonary Arterial Coupling in Schistosomiasis-Associated Pulmonary Arterial HypertensionNot yet recruitingNCT07707193Not applicable1 country
- Expanding Access to Preventive Chemotherapy Among Mobile and Migrant PopulationsRecruitingNCT07707817Not applicable1 country
- MATCHING - feMAle geniTal sCHistosomiasis IN miGrants Female Genital Schistosomiasis in Migrants Presenting to an Outpatient Clinic in Italy: Prevalence and Clinical ImpactRecruitingNCT07484256Not applicable1 country
- Prevalence and Molecular Identification of Human SchistosomiasisNot yet recruitingNCT07482215
- Long-Term Outcomes of Selexipag in Schistosomiasis-Associated Pulmonary Arterial HypertensionNot yet recruitingNCT074530301 country
- Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health PerspectiveRecruitingNCT073589101 country
- Introduction of Arpraziquantel Treatment for Schistosomiasis Control in Preschool-aged Children in Endemic Areas: A Small-scale Public Health Intervention StudyRecruitingNCT066985103 countries
- Assessment of Infection Activity in Travelers and Migrants Diagnosed With Chronic SchistosomiasisRecruitingNCT06873308Not applicable5 countries
- Female Genital Schistosomiasis in Migrant Women: A Pilot StudyNot yet recruitingNCT06828536Not applicable
- Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth ControlNot yet recruitingNCT06182176Not applicable
- Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network ApproachRecruitingNCT06311344Not applicable1 country
- Sm-p80 Schistosomiasis Challenge StudyNot yet recruitingNCT05999825Phase 2
- Health Education Model Led by Community Health Volunteers.CompletedNCT06312462Not applicable1 country
- A Study to Evaluate the Safety, Tolerability, and Immunogenicity of the rSm-p80 + GLA-SE (SchistoShield®) Candidate Vaccine in Healthy Adults in Burkina Faso and MadagascarCompletedNCT05762393Phase 12 countries
- Praziquantel in Children Under Age 4CompletedNCT03640377Phase 22 countries
- Protocol for Integrating Mass Drug Administration Into Primary Health Care in Western KenyaCompletedNCT07507461Not applicable1 country
- Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan AdultsCompletedNCT03910972Phase 1/21 country
- Performance of Tests for Schistosoma Haematobium DiagnosisCompletedNCT068087501 country
- Safety, Tolerability, and Immunogenicity Study of Sm-p80 + GLA-SE (SchistoShield(R)) Vaccine in Healthy AdultsCompletedNCT05292391Phase 11 country
- Delivering a Multi-disease Screening Tool to Migrant PopulationsCompletedNCT05868005Not applicable1 country
- Single-sex Female Controlled Human Schistosomiasis Mansoni InfectionCompletedNCT04269915Not applicable1 country
- L-PZQ ODT in Schistosoma Infected ChildrenCompletedNCT03845140Phase 32 countries
- Helminth Infection During Pregnancy on Vitamin D Regulation: HELMVIT StudyCompletedNCT043248531 country
- Schistosomiasis in SenegalActive, not recruitingNCT03187366Not applicable1 country
- Repeated Controlled Human Schistosoma Mansoni InfectionCompletedNCT05085470Not applicable1 country
- Retrospective Study of Clinical Practice and Management of Imported Schistosomiasis in FranceCompletedNCT048107411 country
- Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African ChildrenStatus unknownNCT05354258Not applicable1 country
- Clinical Evaluation of Ujiplus® Against Schistosoma MansoniCompletedNCT04679831Phase 2/31 country
- Seropositivity and Adverse Birth Events in Migrants From Bilharzia-endemic AreasTerminatedNCT031582981 country
- Schistosomiasis Diagnosis Using a CAA Antigen TestStatus unknownNCT03779347Phase 31 country
- Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African ChildrenCompletedNCT03893097Phase 31 country
- A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed AdultsCompletedNCT03110757Phase 11 country
- Monitoring Schistosome Hybrids Under Under Praziquantel PressureStatus unknownNCT046355531 country
- Single-sex Controlled Human Schistosomiasis Infection: Safety and Dose FindingCompletedNCT02755324Not applicable1 country
- Detection of Schistosomiasis CAA in Travellers After High-risk Water ContactCompletedNCT021947121 country
- Repeated Doses of Praziquantel in Schistosomiasis Treatment (RePST)CompletedNCT02868385Phase 31 country
- Selexipag for the Treatment of Schistosomiasis-Associated Pulmonary Arterial HypertensionStatus unknownNCT04589390Phase 21 country
- Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Parasites Infections.Status unknownNCT045050461 country
- Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept StudyCompletedNCT04115072Phase 2/31 country
- HIV Accelerated Liver Disease in UgandaCompletedNCT015245621 country
- Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With SchistosomiasisWithdrawnNCT02734186Phase 4
- Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School ChildrenCompletedNCT03799510Phase 21 country
- An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni)CompletedNCT02806232Phase 21 country
- Urinary Schistosomiasis InfectionCompletedNCT001384501 country
- Praziquantel-Pharmacokinetic StudyCompletedNCT01288872Phase 11 country
- Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic TreatmentCompletedNCT024959091 country
- Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan AfricaCompletedNCT034583381 country
- Study of Safety and Immune Response of the Sm14 Vaccine in Adults of Endemic RegionsCompletedNCT03041766Phase 21 country