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Leukoencephalopathy, Progressive Multifocal clinical trials

The registry lists 29 studies for Leukoencephalopathy, Progressive Multifocal across 8 countries. 7 are recruiting or about to start. 20 of them are mainly about Leukoencephalopathy, Progressive Multifocal (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29.

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Status

Completed
17
Recruiting
6
Terminated
3
Status unknown
2
Not yet recruiting
1

Phase

Phase 2
9
Early Phase 1
2
Phase 1
2
Phase 3
1
Phase 4
1

Where

United States
17
Germany
5
France
4
Spain
2
China
2
Italy
2

Who runs them

National Institute of Neurological Disorders and Stroke (NINDS) (5) · Biogen (5) · Fondation Ophtalmologique Adolphe de Rothschild (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Beth Israel Deaconess Medical Center (2) · University Hospital, Toulouse (2) · Bristol-Myers Squibb (2) · Cellevolve Bio Inc (1)

What is being tested here

Drugs under test in Leukoencephalopathy, Progressive Multifocal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Pembrolizumab112
Brincidofovir101
Zirconium Zr 89 Crefmirlimab Berdoxam101
Enfuvirtide001
Efineptakin alfa001
Cytarabine001
Cidofovir001
Didanosine001
Topotecan001
Zidovudine001

Coming up

1phase 3 study under way
1study finishes main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The study

Who these studies take

Of the 6 Leukoencephalopathy, Progressive Multifocal studies recruiting now, 3 (50%) set no upper age limit and 0 (0%) stop at 75 or younger. 3 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (17%) take healthy volunteers.

Recruiting studies that take each age, of 6
AgeWomenMen
102 (33%)2 (33%)
186 (100%)6 (100%)
306 (100%)6 (100%)
406 (100%)6 (100%)
506 (100%)6 (100%)
656 (100%)6 (100%)
756 (100%)6 (100%)
856 (100%)6 (100%)

Across all 29 studies, recruiting or not: 17% stop at 75 or younger and 14% at 65; 24% take children; 0% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 29 of 29. search them.