Drug
Medroxyprogesterone Acetate clinical trials
Also written DMPA, Provera, Depo-Provera and TV-46046.
A product of Medroxyprogesterone; its studies count on that page too.
Keep track of what changes. Save the Medroxyprogesterone Acetate studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Other names
- DMPA
- 14
Studies by the year they started
74 studies that test it; most in 2015 (9)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 1999 | 1 |
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 3 |
| 2008 | 2 |
| 2009 | 3 |
| 2010 | 4 |
| 2011 | 3 |
| 2012 | 2 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 9 |
| 2016 | 1 |
| 2017 | 5 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 2 |
| 2021 | 3 |
| 2022 | 3 |
| 2023 | 6 |
| 2024 | 1 |
| 2025 | 4 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 9 · Other 65
FHI 360 (5) · Teva Branded Pharmaceutical Products R&D, Inc. (3) · Pfizer (2) · University of Washington (2) · Assiut University (2) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (2) · Botswana Harvard AIDS Institute Partnership (1) · Northwestern University (1)
Often tested with
Tested in the same studies.
Levonorgestrel (3) · Conjugated estrogens (3) · Contraceptives, Oral, Combined (2) · Dydrogesterone (2) · Estradiol (2) · Megestrol Acetate (2) · Megestrol (2) · Letrozole (2)
Studies
Open first, then newest update. How each study uses Medroxyprogesterone Acetate is read from its arms, and is right about nine times in ten.
Testing it · 74
- A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)RecruitingPhase 2Merck Sharp & Dohme LLCNCT06979596Written as Megestrol acetate/Medroxyprogesterone acetate
- Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell DiseaseRecruitingPhase 4University of PennsylvaniaNCT06665997Written as Depot medroxyprogesterone acetate (DMPA)
- Refining Fertility-sparing Treatment in Endometrial Carcinoma Based on Molecular ClassificationRecruitingPhase 2/3Fudan UniversityNCT07319429Written as Medroxyprogesterone Acetate 500 MG
- Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-ANot yet recruitingPhase 3ShangHai Ji Ai Genetics & IVF InstituteNCT05326087Written as MPA
- Nanocrystalline Megestrol for Managing Chemotherapy-Induced Nausea and VomitingNot yet recruitingPhase 3The First Affiliated Hospital of Xinxiang Medical CollegeNCT07124195Written as Medroxyprogesterone acetate oral suspension
- Protocol with Progestin-primed Ovarian Stimulation (PPOS) from the Beginning of Stimulation Versus Protocol with GnRH Antagonists for Ovarian Stimulation in Patients Undergoing DUOSTIM with Embryo Accumulation for PGT-A.Not yet recruitingPhase 4GinefivNCT06637189Written as Medroxyprogesterone Acetate 10 MG
- Medroxyprogesterone Acetate Plus Atorvastatin in Young Women With Early Endometrial Carcinoma and Atypical Endometrial HyperplasiaRecruitingPhase 2Peking University People's HospitalNCT05675787Written as Medroxyprogesterone acetate + Atorvastatin
- Medroxyprogesterone Acetate vs LNG-IUS in Early-stage Endometrioid Carcinoma and Atypical Hyperplasia PatientsRecruitingPhase 2/3Hua LiNCT05565573Written as Medroxyprogesterone Acetate 500 MG Oral Tablet
- Continuation of Subcutaneous and Intramuscular Depot Medroxyprogesterone Acetate in Post-abortion PatientsCompletedPhase 4Northwestern UniversityNCT05505435Written as Depot-Medroxyprogestereone Acetate
- Endometrial Biopsy in Progestin Contraceptive UsersCompletedEarly Phase 1Oregon Health and Science UniversityNCT05760144Written as DMPA
- Risk Evaluation and Screening to Tailor Prevention and Reduce the Incidence of Endometrial CancerCompletedPhase 4University of British ColumbiaNCT05651282Written as Provera
- Measuring Lactation Initiation After Early Postpartum Injectable Progestin (DMPA) Use Among Women in Dhanusha District of Nepal: A Pilot StudyCompletedPhase 4University of California, San DiegoNCT06816901Written as Depo Medroxyprogesterone acetate
- A Study Comparing Subcutaneous Injection of Sayana Press In the Upper Arm Versus Anterior Thigh and AbdomenCompletedPhase 1PfizerNCT04893798Written as Sayana Press
- Comparing the Safety and Efficacy in the Use of Hormonal Therapy on Endometriosis Patients After Conservative SurgeryCompletedPhase 3Universitas DiponegoroNCT06145438Written as Depo Medroxyprogesterone acetate
- Comparison of 3 Different Protocols for Preventing Premature Ovulation in Ovarian Stimulation CyclesCompletedNot applicableBezmialem Vakif UniversityNCT05767086Written as Medroxyprogesterone Acetate (Tarlusal)
- Sayana® Press Extension StudyCompletedPhase 3FHI 360NCT03154125Written as Sayana® Press
- Medroxyprogesterone Acetate Injection 150 mg/1 mL in Postmenopausal WomenCompletedPhase 1Teva Pharmaceuticals USANCT00830414Written as medroxyprogesterone acetate
- The Kampala Women's Bone StudyCompletedPhase 4University of WashingtonNCT03464266Written as FTC/TDF and DMPA
- Postpartum Family PlanningTerminatedPhase 4Ohio State UniversityNCT03844633Written as Depo-Provera Injectable Product
- Tranexamic Acid and Depot-Medroxyprogesterone Acetate for Perimenopausal Irregular Uterine BleedingCompletedNot applicableAssiut UniversityNCT04710017Written as Medroxyprogesterone Acetate 150 MG/ML
See all 74 studies that test Medroxyprogesterone Acetate →
Given in every arm · 10 — Medroxyprogesterone Acetate is usual care beside what is tested
- A Study of TCD601 in de Novo Renal Transplant RecipientsCompletedPhase 2ITB-Med LLCNCT05669001Written as MPA
- Estrogen Receptor Beta and MoodCompletedPhase 2National Institute of Mental Health (NIMH)NCT03689543Written as Provera
- Pilot Study of Femring Estrogen Supplementation During Depo-Provera InitiationCompletedNot applicableColumbia UniversityNCT00563576Written as DepoProvera ®
- Medroxyprogesterone Acetate With or Without Entinostat Before Surgery in Treating Patients With Endometrioid Endometrial CancerCompletedEarly Phase 1National Cancer Institute (NCI)NCT03018249Written as Medroxyprogesterone Acetate
- Research Investigation of Soy and EstrogenCompletedPhase 2University of Illinois at ChicagoNCT00997893Written as Medroxyprogesterone Acetate (MPA)
- Safety and Efficacy of Basiliximab in Calcineurin Inhibitor Intolerant Long-term Kidney Transplant Recipients Treated With Mycophenolic Acid and SteroidsCompletedPhase 4NovartisNCT00284947Written as MMF/EC-MPS
- Contraception and Menstrual Cycle Effect on Pharmacokinetics, Pharmacodynamics and Safety in Tenofovir Vaginal Gel UseCompletedPhase 1CONRADNCT01421368Written as Depo-medroxyprogesterone acetate (DMPA)
- Somatropin Treatment to Final Height in Turner SyndromeCompletedPhase 3Eli Lilly and CompanyNCT00191113Written as Medroxyprogesterone acetate
- Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration AddendumCompletedPhase 1/2University of WashingtonNCT00156650Written as Depo-Medroxyprogesterone
- Male Hormonal Contraceptive Development-ACY-5CompletedPhase 1/2University of WashingtonNCT00161447Written as Depo-Medroxyprogesterone
As the comparator · 15 — what is tested is compared with Medroxyprogesterone Acetate
- Oral GnRH Antagonist (Linzagolix) Versus Injectable GnRH Antagonist in Controlled Ovarian Stimulation for In Vitro Fertilization: A Randomized Controlled Non-Inferiority Trial With a Concurrent Comparator Cohort Undergoing Progestin-Primed Ovarian Stimulation (PPOS)Not yet recruitingNot applicableCentro A.M.B.R.A. (Associazione Medici e Biologi per la Riproduzione Assistita)NCT07732348Written as Medroxyprogesterone Acetate ; Micronized Progesterone
- Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial CancerActive, not recruitingPhase 2Fudan UniversityNCT05247268Written as Medroxyprogesterone Acetate 500 MG
- Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 MonthsWithdrawnPhase 3BayerNCT06904274Written as Medroxyprogesterone acetate
- Everolimus and Letrozole or Hormonal Therapy to Treat Endometrial CancerCompletedPhase 2GOG FoundationNCT02228681Written as Medroxyprogesterone Acetate
- The Impact of Hormone Therapy on Lower Urinary Tract Symptoms, Sexual Function and Psychosomatic DisorderCompletedPhase 4Far Eastern Memorial HospitalNCT01822288Written as Estradiol & medroxyprogesterone acetate
- Tibolone Endometrium Study (Study 32972)(P06470)CompletedPhase 3Organon and CoNCT00745108Written as CE/MPA
- Elagolix Versus Subcutaneous Depot Medroxyprogesterone Acetate for the Treatment of EndometriosisCompletedPhase 2AbbVieNCT00437658Written as Subcutaneous depot medroxyprogesterone acetate (DMPA-SC)
- Efficacy of Cyclic DSG Compared With Cyclic MPA for the Treatment of Anovulatory DUBStatus unknownPhase 3Mahidol UniversityNCT02103764Written as Medroxyprogesterone acetate
- Bioidentical 'Natural' Hormone Evaluation in Early MenopauseTerminatedPhase 2Jeanne Drisko, MD, CNS, FACNNCT00302731Written as equine estrogens m-progesteroneacetate
- Lower Dose Depo Provera® Contraceptive InjectionCompletedPhase 1FHI 360NCT02732418Written as Depo-subQ 104
- "Stair Step Study"CompletedPhase 4Radboud University Medical CenterNCT03309176Written as Medroxyprogesterone Acetate 10 MG
- Long-Acting Reversible ContraceptionCompletedPhase 4FHI 360NCT01299116Written as DMPA
- Safety of the Etonogestrel-releasing Implant During the Puerperium of Healthy WomenCompletedNot applicableUniversity of Sao PauloNCT00828542Written as depot medroxyprogesterone acetate
- Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)CompletedPhase 3BayerNCT00360490Written as Medroxyprogesterone acetate
- Multi-centre Clinical Trial on Hormone Replacement Treatment in ChinaStatus unknownPhase 4Peking Union Medical College HospitalNCT01698164Written as estradiol plus MPA
Codes
What other systems call Medroxyprogesterone Acetate · ClinicalTrials.gg INT008565
- MeSH (NLM) D017258Medroxyprogesterone AcetateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) C2QI4IOI2GMEDROXYPROGESTERONE ACETATEConfirmed FDA, NLM, Wikidata
- RxNorm 1000112Confirmed FDA, Wikidata
- Wikidata Q2823834medroxyprogesterone acetateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1155Medroxyprogesterone AcetateOne source FDA
- DrugBank DB00603One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D017258 | Medroxyprogesterone Acetate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | C2QI4IOI2G | MEDROXYPROGESTERONE ACETATE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1000112 | — | Confirmed FDA, Wikidata |
| Wikidata | Q2823834 | medroxyprogesterone acetate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1155 | Medroxyprogesterone Acetate | One source FDA |
| DrugBank | DB00603 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.