Janus Kinase Inhibitors: all 1,428 studies that test it
Page 1 of 15. Open to participants first (328), then studies with results posted, then the rest; newest registration first within each.
- A Study of Zasocitinib in Adults With Psoriatic Arthritis (LATITUDE PsA NeXt)Not yet recruitingNCT07871721Phase 3
- Safety, Efficacy and Pharmacokinetics of TT00420 Tablets Combined With Novel Endocrine Therapy in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC)RecruitingNCT07871110Phase 2
- A Phase 3 Study of Povorcitinib Phosphate in Chinese Adults With Nonsegmental VitiligoNot yet recruitingNCT07865312Phase 3
- A Study to Evaluate DMR-001 in Participants With CALR-mutant Myeloproliferative NeoplasmsRecruitingNCT07849231Phase 1
- Abrocitinib Dose Tapering in Patients With Atopic DermatitisNot yet recruitingNCT07848074Phase 4
- JAK1 Inhibitor Ivarmacitinib for Improving Pancreatic Islet Function in T1DNot yet recruitingNCT07845955Phase 2
- A Study to Evaluate the Safety and Pharmacokinetics of Multiple Doses Upadacitinib, Tofacitinib, and Baricitinib in Healthy Adult VolunteersRecruitingNCT07843693Phase 1
- Safety and Efficacy of Ruxolitinib in Patients With HNSCC and High NLR Treated With Pembrolizumab - The Phase 2 InflammaSTOP TrialNot yet recruitingNCT07840456Phase 2
- Abrocitinib Treatment of Atopic Dermatitis in Children 2 to Less Than 6 Years of AgeNot yet recruitingNCT07823595Phase 3
- Ivarmacitinib Versus Glucocorticoids in Mild-to-Moderate Systemic Lupus ErythematosusNot yet recruitingNCT07814664Phase 2/3
- Topical Ruxolitinib in Acute Skin GVHD (Graft Versus Host Disease)Not yet recruitingNCT07801248Phase 1
- Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNINot yet recruitingNCT07796620Phase 1/2
- Continued Access to Deucravacitinib for Adult SLE/SjD and Pediatric PsO/PsA Study CompletersNot yet recruitingNCT07791199Phase 3
- Topical Ruxolitinib in the Treatment of Adults With Pyoderma GangrenosumRecruitingNCT07783412Phase 2
- Topical JAK-Inhibition of Early-Stage CTCLNot yet recruitingNCT07781449Phase 2
- Precision Medicine Adaptive Network Platform Trial in Hypoxemic Acute Respiratory FailureNot yet recruitingNCT07779642Phase 2
- A Study to Evaluate the Safety and Effectiveness of Upadacitinib in Pediatric Participants With Alopecia AreataRecruitingNCT07772492Phase 3
- A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor Necrosis Factor-alpha Inhibitor Failure in Axial SpondyloarthritisNot yet recruitingNCT07770646Phase 4
- Golidocitinib and Chidamide for Cutaneous T-Cell LymphomaRecruitingNCT07754890Phase 1/2
- Golidocitinib Plus Anthracycline-based Therapy for Untreated Nodal T-follicular Helper (TFH) Cell LymphomaNot yet recruitingNCT07753642Phase 2
- A Study of Zasocitinib in Adults With Non-pustular Palmoplantar PsoriasisNot yet recruitingNCT07752108Phase 3
- Efficacy and Safety of Golidocitinib for Rapidly Progressive Interstitial Lung DiseaseNot yet recruitingNCT07737249Phase 2
- A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment of Patchy Hair Loss, Known by the Medical Term as Moderate Alopecia AreataRecruitingNCT07733765Phase 3
- Efficacy of Upadacitinib Re-induction Therapy in Patients With Ulcerative Colitis Who Lost Response to 30 mg Maintenance DoseNot yet recruitingNCT07700446Phase 4
- Golidocitinib in Patients With Mycosis Fungoides/Sézary Syndrome and T-Cell Large Granular Lymphocytic LeukemiaNot yet recruitingNCT07682792Phase 2
- Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative NeoplasmsNot yet recruitingNCT07679334Phase 1
- The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe ItchingNot yet recruitingNCT07678645Phase 2
- Trial of Delgocitinib 20 mg/g Cream in Subjects With Frontal Fibrosing Alopecia (FFA)Not yet recruitingNCT07671157Phase 2
- Upadacitinib in Treatment of JAK/STAT Pathway Disorders With Activating MutationsNot yet recruitingNCT07670156Phase 1/2
- TPO-RA Plus Baricitinib vs. TPO-RA for ITPNot yet recruitingNCT07669675Phase 2
- Opzelura Experience StudyNot yet recruitingNCT07661979Phase 4
- Belumosudil With Ruxolitnib as Third Line Therapy for Chronic Graft Versus Host Disease (cGvHD)Not yet recruitingNCT07643025Phase 2
- Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Japanese Adults With Severe Alopecia AreataRecruitingNCT07617597Phase 3
- JAK Signaling in Depression and Cognition in Male Football PlayersRecruitingNCT07608796Phase 2
- Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1RecruitingNCT07598643Phase 2
- Efficacy and Safety of Ruxolitinib Cream in Chinese Children Aged 2-11 Years With Non-segmental VitiligoNot yet recruitingNCT07595939Phase 3
- daGOAT-Guided Prevention of Severe aGVHD After Allo-HSCTNot yet recruitingNCT07588945Phase 3
- A Trial of Upadacitinib for Non-responsive Eosinophilic EsophagitisRecruitingNCT07588568Phase 2
- Comparison of Methotrexate and Tofacitinib in Chronic Plaque PsoriasisNot yet recruitingNCT07581418Not applicable
- A Study Evaluating the Efficacy and Safety of Momelotinib in Participants With Vacuoles, E1-enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) SyndromeNot yet recruitingNCT07569081Phase 2/3
- A Phase I Study to Evaluate the Safety and Efficacy of L19IL2 in Combination With Ruxolitinib in Patients With Advanced Solid TumorsNot yet recruitingNCT07566897Phase 1
- Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIALRecruitingNCT07554820Phase 4
- Safety, Tolerability, Pharmacokinetics, and Efficacy of Filgotinib for the Treatment of Polyarticular-course Juvenile Idiopathic Arthritis in Children and AdolescentsRecruitingNCT07554495Phase 3
- OLE Study With Filgotinib in JIARecruitingNCT07553182Phase 3
- A Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of TQ05105 Tablets in Subjects With Intermediate/High-risk MyelofibrosisRecruitingNCT07551427Phase 2
- Upadacitinib Versus Infliximab as Second-Line Treatment for Acute Severe Ulcerative Colitis（UPRISE）RecruitingNCT07550673Phase 4
- Efficacy and Safety of Switching to Ivarmacitinib in Patients With Moderate-to-Severe Atopic Dermatitis With Inadequate Response to Interleukin-4 Receptor Alpha(IL-4Rα) Inhibitors: A Prospective, Multicenter, Real-World StudyNot yet recruitingNCT07550452Not applicable
- Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell TransplantationRecruitingNCT07548983Phase 1
- Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye DiseaseRecruitingNCT07547930Phase 2
- Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis（UPFRONT）RecruitingNCT07546097Phase 4
- Therapeutics for Moderate and Severe DengueNot yet recruitingNCT07543458Phase 3
- Baricitinib for Post-HSCT Persistent ThrombocytopeniaRecruitingNCT07535645Phase 1/2
- A Phase 2/3 Study of Brepocitinib in Adults With Lichen PlanopilarisRecruitingNCT07532603Phase 2/3
- A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe AsthmaRecruitingNCT07532265Phase 2
- Tofacitinib Plus Imatinib in Moderate-to-Severe Palmoplantar PustulosisNot yet recruitingNCT07530367Phase 3
- Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)RecruitingNCT07525466Phase 1/2
- A Precision Medicine Trial for Patients With Relapsed or Refractory T Cell ALLNot yet recruitingNCT07522801Phase 2
- Tolerability of Ropeginterferon Alfa-2b Add-on to Ongoing Ruxolitinib Therapy in MyelofibrosisRecruitingNCT07521046Phase 1
- TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal ResponseRecruitingNCT07510191Phase 4
- Novel Therapies for Severe Acute GVHD (Graft-versus-host Disease)RecruitingNCT07509749Phase 2
- Deucravacitinib in the Treatment of Cicatricial AlopeciasRecruitingNCT07508488Phase 2
- Camrelizumab, Chemotherapy and Ivarmacitinib in Patients With Resectable Esophageal Squamous Cell CarcinomaRecruitingNCT07505186Phase 2
- Upadacitinib in Patients Hospitalized With Acute Severe Ulcerative ColitisNot yet recruitingNCT07502339Phase 4
- Efficacy and Safety of Tinengotinib Tablets Combined With Fulvestrant Injection in Patients With HR Positive and HER-2 Negative Recurrent or Metastatic Breast Cancer Who Have Failed Prior TreatmentRecruitingNCT07498478Phase 2
- Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell CountsNot yet recruitingNCT07498205Phase 4
- Genotype-guided Targeted Agents Plus EZH2i for Primary Refractory PTCLNot yet recruitingNCT07493330Phase 1/2
- Upadacitinib in Adult Patients With Erosive Mucosal Lichen Planus and Lichen Planopilaris: a Prospective Multicenter Randomized Placebo-controlled Study.RecruitingNCT07492251Phase 2
- Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen PlanopilarisRecruitingNCT07487948Phase 2
- To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Hepatic Impairment SubjectsRecruitingNCT07480824Phase 1
- A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative NeoplasmsRecruitingNCT07469891Phase 1
- CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid LeukemiaRecruitingNCT07464951Phase 1
- Efficacy and Safety of Ivarmacitinib Monotherapy in the Treatment of csDMARDs-IR Rheumatoid ArthritisNot yet recruitingNCT07452445Phase 4
- Efficacy and Safety of Vunakizumab and Ivarmacitinib in the Treatment of Active Takayasu's ArteritisNot yet recruitingNCT07451665Phase 4
- Safety and Efficacy of Baricitinib After Endovascular Treatment in Acute Anterior Circulation Large Vessel Occlusion: A Multicenter, Randomized Controlled Clinical TrialNot yet recruitingNCT07449910Phase 2/3
- Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With CytopeniasNot yet recruitingNCT07447817Phase 2
- A Clinical Trial of Flonoltinib Maleate Tablets in the Treatment of JAK Inhibitor Refractory/Relapsed/Intolerant Patients With Intermediate to High Risk MyelofibrosisRecruitingNCT07443306Phase 2
- Ruxolitinib for Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (RISE)RecruitingNCT07424222Phase 1
- Golidocitinib Versus Placebo as Maintenance Therapy in PTCL Patients With Response (CR/PR) After First-Line ChemotherapyRecruitingNCT07414758Phase 3
- A Study on the Efficacy and Safety of JAK Inhibitors Versus Calcineurin Inhibitors as Initial Therapy for Interstitial Lung Disease Associated With Antisynthetase SyndromeRecruitingNCT07406932Not applicable
- Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA)Not yet recruitingNCT07406204Phase 4
- A Study of Zasocitinib (TAK-279) in Adults With Active Crohn's DiseaseRecruitingNCT07403968Phase 2
- Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have ThrombocytopeniaRecruitingNCT07394153Phase 2
- A Clinical Study on the Efficacy and Safety of Ivarmacitinib in Preventing aGVHD After HLA-matched TransplantationNot yet recruitingNCT07381114Phase 1/2
- Golidocitinib Combined With Selinexor for CAEBVDRecruitingNCT07369739Phase 2/3
- Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic MalignanciesRecruitingNCT07366801Phase 2/3
- A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell TransplantRecruitingNCT07359859Phase 2
- Baricitinib Effects on Procoagulant State in Rheumatoid ArthritisNot yet recruitingNCT07357649Phase 4
- Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell LymphomaRecruitingNCT07356245Phase 2
- Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingNCT07352566Phase 4
- The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic RosaceaRecruitingNCT07343635Not applicable
- Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease )RecruitingNCT07340723Phase 2
- Prospective Single-Arm Clinical Trial of GO Regimen for HLH.RecruitingNCT07339345Phase 2/3
- A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen SclerosusRecruitingNCT07335588Phase 3
- Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or MutationsNot yet recruitingNCT07328919Phase 3
- Ivarmacitinib in Advanced Solid Tumors: A Prospective, Two-Cohort, Two-Phase Exploratory Study in Patients Discontinued Due to Immune IntoleranceNot yet recruitingNCT07313202Phase 2
- Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic LeukemiaRecruitingNCT07311746Phase 1/2
- Golidocitinib for Refractory Immune-related Hematologic Toxicities of Advanced Lung CancerNot yet recruitingNCT07303881Phase 2
- Golidocitinib Versus Placebo as Maintenance Therapy for Peripheral T-Cell LymphomaRecruitingNCT07300514Phase 3
- Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALLRecruitingNCT07297914Phase 2/3
- Safety and Efficacy of the JAK1 Inhibitor Combined With Intensive Immunosuppressive Therapy in Severe Aplastic AnemiaNot yet recruitingNCT07297550Phase 1/2