Drug
Interferon gamma-1b clinical trials
Also written Actimmune.
A product of Interferon Gamma; its studies count on that page too.
- studies test it
- 39
- open now
- 2
- in phase 3
- 9
- first study started
- 2000
Keep track of what changes. Save the interferon gamma-1b studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
37 studies that test it; most in 2001 (5)
| Year | Studies |
|---|---|
| 2000 | 3 |
| 2001 | 5 |
| 2002 | 3 |
| 2003 | 3 |
| 2006 | 1 |
| 2008 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 2 |
| 2012 | 1 |
| 2013 | 2 |
| 2015 | 3 |
| 2016 | 4 |
| 2017 | 2 |
| 2021 | 2 |
| 2022 | 1 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 12
- Phase 2
- 21
- Phase 3
- 9
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 18 · Other 21
InterMune (13) · Amgen (4) · National Eye Institute (NEI) (4) · National Cancer Institute (NCI) (3) · Radboud University Medical Center (1) · Sawa Ito, MD (1) · Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
Often tested with
Tested in the same studies.
Pembrolizumab (1) · Tocilizumab (1) · Baricitinib (1) · Interleukin 1 Receptor Antagonist Protein (1) · Hydrocortisone (1) · Fludrocortisone (1) · Heparin (1) · Heparin, Low-Molecular-Weight (1)
Studies
Open first, then newest update. How each study uses interferon gamma-1b is read from its arms, and is right about nine times in ten.
Testing it · 39
- Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket TrialRecruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT06381661Written as Interferon gamma-1b
- Prevention of Secondary Infections by Interferon Gamma in ICU-acquired Sustained Immune-suppressionRecruitingPhase 3University Hospital, LimogesNCT06774235Written as Interferon Gamma 1-b
- Safety and Efficacy of Interferon-Gamma 1b in Patients With CandidemiaCompletedPhase 2Radboud University Medical CenterNCT04979052Written as Interferon Gamma-1B
- Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal CancerTerminatedPhase 1National Cancer Institute (NCI)NCT02948426Written as Autologous Monocytes + ACTIMMUNE + SYLATRON
- IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell TransplantationCompletedEarly Phase 1Sawa Ito, MDNCT04628338Written as IFN-γ (interferon gamma-1b) injection
- Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's AtaxiaCompletedPhase 3AmgenNCT02415127Written as Interferon γ-1b
- Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia StudyCompletedPhase 3AmgenNCT02593773Written as Interferon γ-1b
- Long-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich's AtaxiaCompletedPhase 3AmgenNCT02797080Written as interferon γ-1b
- ACTIMMUNE in Intermediate OsteopetrosisCompletedPhase 2Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterNCT02666768Written as Interferon gamma-1b
- Topical Interferon Gamma-1b for Central Serous ChorioretinopathyCompletedPhase 1/2National Eye Institute (NEI)NCT01468337Written as Interferon gamma-1b
- Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial SarcomaCompletedPhase 2National Cancer Institute (NCI)NCT03063632Written as Interferon Gamma-1b
- Human Recombinant Interferon Gamma-1b for the Prevention of Hospital-acquired Pneumonia in Critically Ill Patients: a Double-blind, International, Phase 2, Randomized, Placebo-controlled Trial - the PREV-HAP StudyStatus unknownPhase 2Nantes University HospitalNCT04793568Written as Recombinant Interferon gamma 1b (IMUKIN®)
- Phase I/II Study of Recombinant Human Interferon-gamma (rIFN-gamma) in HIV-Infected ChildrenCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT00000761Written as Interferon gamma-1b
- Interferon Gamma-1b in Friedreich Ataxia (FRDA)CompletedPhase 2Children's Hospital of PhiladelphiaNCT01965327Written as Interferon Gamma-1b
- Use of ACTIMMUNE in Patients With ADO2CompletedPhase 2Indiana UniversityNCT02584608Written as ACTIMMUNE
- HGS-ETR2 to Treat Children With Solid TumorsTerminatedPhase 1National Cancer Institute (NCI)NCT00428272Written as Interferon gamma 1b in combination
- Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)TerminatedPhase 1/2National Eye Institute (NEI)NCT02338973Written as Interferon gamma-1b
- Effect of IFN-γ on Innate Immune CellsCompletedPhase 1University of Colorado, DenverNCT02609932Written as Administration of drug (Interferon-gamma 1-b) subcutaneously
- The Treatment of Uveitic Cystoid Macular Edema With Topical Interferon GammaCompletedPhase 1National Eye Institute (NEI)NCT00943982Written as Interferon Gamma 1-b
- Determining the Effect of Actimmune (Interferon Gamma 1b)Dose Titration on Flu-Like Symptoms in Healthy VolunteersStatus unknownPhase 1Vidara Therapeutics Research LtdNCT01929382Written as interferon gamma 1b
See all 39 studies that test interferon gamma-1b →
Given in every arm · 3 — interferon gamma-1b is usual care beside what is tested
- Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell TransplantationRecruitingPhase 2Sawa Ito, MDNCT06529731Written as Interferon gamma-1b
- Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell CancerTerminatedPhase 1/2Fred Hutchinson Cancer CenterNCT03747484Written as Interferon Gamma-1b
- Study of Gamma Interfereon in Metastatic Colorectal CarcinomaCompletedPhase 2Accelerated Community Oncology Research NetworkNCT00786643Written as Gamma-Interferon-1b (IFN-γ)
Codes
What other systems call interferon gamma-1b · ClinicalTrials.gg INT005749
- MeSH (NLM) C554125interferon gamma-1bOne source NLM
- UNII (FDA) 21K6M2I7AGINTERFERON GAMMA-1BConfirmed FDA, NLM, Wikidata
- RxNorm 5882Confirmed FDA, Wikidata
- Wikidata Q582356interferon gamma-1bConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C100089Interferon Gamma-1bOne source FDA
- DrugBank DB00033One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C554125 | interferon gamma-1b | One source NLM |
| UNII (FDA) | 21K6M2I7AG | INTERFERON GAMMA-1B | Confirmed FDA, NLM, Wikidata |
| RxNorm | 5882 | — | Confirmed FDA, Wikidata |
| Wikidata | Q582356 | interferon gamma-1b | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C100089 | Interferon Gamma-1b | One source FDA |
| DrugBank | DB00033 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.