Hypnotics and Sedatives: all 2,749 studies that test it

Page 23 of 28. Open to participants first (425), then studies with results posted, then the rest; newest registration first within each.

• Dexmedetomidine for Postoperative Analgesia After Bariatric SurgeryCompletedNCT02213159Phase 2/3
• Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40 in VitrectomyCompletedNCT02212340Not applicable
• Sedation and Physiological Effects of Intranasal Dexmedetomidine in Severe COPDCompletedNCT02211118Phase 4
• The Feasibility of Different Doses of Etomidate Admixed With Propofol in Induced Abortion: A Randomized, Double Blind Controlled TrialStatus unknownNCT02208596Phase 4
• Antitussive Effect of Single-dose Dexmedetomidine With Low-dose Remifentanil InfusionCompletedNCT02208505Phase 4
• The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol AnesthesiaCompletedNCT02203097Phase 4
• Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic PatientsStatus unknownNCT02202239Phase 4
• Pilot Study of Sedation With Propofol in Refractory Pains Due to Care in Palliative Care UnitCompletedNCT02198404Phase 4
• Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol DrinkerStatus unknownNCT02197403Phase 4
• The Role of Melatonin in the Effective Attainment of Sleep Electroencephalograms (EEG) in ChildrenCompletedNCT02195661Phase 3
• Effect of Anesthetics on Oxygenation and Microcirculation During One-lung VentilationCompletedNCT02191371Not applicable
• Dexmedetomidine Pharmacokinetics in the ObeseCompletedNCT02187068Phase 4
• Comparison of Etomidate, Propofol and Etomidate-propofol Combination in Terms of Effects on Haemodynamic Response to IntubationCompletedNCT02186990Phase 4
• Effects of Dexmedetomidine on Respiratory Mechanics and Oxygenation During One Lung Ventilation With Chronic Obstructive Lung DiseaseCompletedNCT02185430Not applicable
• Bispectral Index Guiding Etomidate Used in Children Aged 3 to 10 for Clinical Anesthesia InductionStatus unknownNCT02182648Phase 4
• Multiple Doses of BI 207127 NA, BI 201335 NA Followed by the Combination of BI 207127 NA and BI 201335 NA in Healthy Male VolunteersTerminatedNCT02182401Phase 1
• Moderate Sedation for Elective Upper Endoscopy With Balanced Propofol Versus Propofol Alone: a Randomized Clinical TrialCompletedNCT02174588Not applicable
• The Application of Target Controlled Infusion of Etomidate Combined With Propofol in the Maintenance of Anesthesia During Brain SurgeriesStatus unknownNCT02174120Phase 4
• Safety and Efficacy of Fentanyl Citrate in ChildrenCompletedNCT02172014Phase 2
• The Effectiveness of the Addition of Dexmedetomidine to Analgesia for Ankle Surgery.TerminatedNCT02170948Not applicable
• Small Doses of Dexmedetomidine for Emergence AgitationStatus unknownNCT02169843Phase 4
• Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study)CompletedNCT02166853Phase 4
• A Comparison of Sedative Drugs for Conscious Sedation During Ultrasound Guided Transbronchial Needle AspirationCompletedNCT02157818Not applicable
• Dexmedetomidine Influence on the Level of Perioperative Blood Glucose and Insulin of Elderly Diabetes PatientsStatus unknownNCT02154074Phase 4
• Comparison of Propofol 1mg/kg and Propofol 0.5mg/kg for Prevention of Emergence Agitation in Children Undergoing Strabismus Surgery During Sevoflurane AnesthesiaStatus unknownNCT02152787Not applicable
• Different Hemostasis According to the Anesthetic AgentsCompletedNCT02151305Not applicable
• The Effect of Propofol Based Total Intravenous Anesthesia on Oxidative Stress and Nitric OxideCompletedNCT02149628Phase 4
• A Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Midazolam in Healthy SubjectsCompletedNCT02147808Phase 1
• A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly PatientsStatus unknownNCT02147678Phase 4
• Postoperative Sleep Quality of Patients Anesthesia With Propofol or Sevoflurane Undergoing ThyroidectomyCompletedNCT02146976Phase 4
• Postoperative Sleep Quality of Patients Sedation With i.v. Dexmedetomidine or Midazolam Undergoing TURPCompletedNCT02142595Phase 4
• Intravenous Dexmedetomidine For The Quaity Of Emergence From General AnesthesiaCompletedNCT02141412Phase 4
• To Evaluate the Effect of AZD1722 on the Pharmacokinetics of Oral Midazolam in Healthy VolunteersCompletedNCT02140268Phase 1
• Efficacy of Dexmedetomidine in Preventing Contrast Induced NephropathyCompletedNCT02137863Phase 4
• Effect of Anesthetics on CD39 and CD73 After Open-heart SurgeryCompletedNCT02136979Phase 4
• Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal AnesthesiaCompletedNCT02136641Phase 4
• Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune StatusStatus unknownNCT02135055Phase 4
• Clobazam Use in Epilepsia Partialis Continua - Pilot StudyTerminatedNCT02134366Phase 3
• Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder PatientsStatus unknownNCT02134093Phase 4
• Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During SurgeryStatus unknownNCT02133638Phase 4
• The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged SurgeryStatus unknownNCT02123355Phase 4
• Transverse Abdominal Block for Analgesia in Casarean SectionCompletedNCT02122510Not applicable
• Sequential Use of Propofol/Midazolam and Dexmedetomidine for Sedation in Mechenical Ventialtion Patients in ICU.Status unknownNCT02122055Phase 4
• Impact of Various Sedation Regimens on the Incidence of DeliriumStatus unknownNCT02117726Phase 4
• The Effect of Induction Technique on Postoperative Pain and AgitationCompletedNCT02110745Phase 4
• The Effect of Dexmedetomidine on Microcirculation in Severe SepsisTerminatedNCT02109965Phase 4
• Preop Dexmedetomidine Attenuates Haemodynamic Responses to HydrodissectionCompletedNCT02102139Phase 4
• Preoperative Dexmedetomidine & EC50 of PropofolCompletedNCT02097407Phase 4
• Neuroprotection With Dexmedetomidine in Patients Undergoing Elective Cardiac or Abdominal Surgery (Neuprodex)CompletedNCT02096068Phase 4
• Comparison of Preemptive Analgesic Effects of Dexketoprofen Versus Dexmedetomidine on Abdominal Hysterectomy PatientsStatus unknownNCT02092012Phase 4
• Anesthetic Advantages of Dexmedetomidine for Hypotensive AnesthesiaCompletedNCT02083055Not applicable
• Safety and Efficacy of Combined Sedation With Midazolam and Dexmedetomidine in ICU PatientsStatus unknownNCT02080169Phase 4
• Effects of Desflurane Versus Propofol on Hemostasis During SplenectomyCompletedNCT02079064Not applicable
• Intranasal Dexmedetomidine Sedation for Ophthalmic Examinations in ChildrenStatus unknownNCT02077712Not applicable
• Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric PatientsCompletedNCT02072083Phase 4
• A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain InjuryStatus unknownNCT02071407Phase 4
• The Efficacy And Cognitive Impairment Of Modified Electroconvulsive TherapyCompletedNCT02066077Not applicable
• Three Anxiolytic Drugs Used in Third Molar SurgeryCompletedNCT02065843Phase 2/3
• Postoperative Analgesic Effects of Dexmedetomidine for Transversus Abdominis Plane BlockCompletedNCT02064530Phase 4
• The Effects of the Drugs Used in Hypotensive Anaesthesia on CochleaCompletedNCT02062333Phase 4
• TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary ResuscitationCompletedNCT02056236Not applicable
• The Effect of Midazolam on Fluid Responsiveness in Septic PatientsCompletedNCT02050893Phase 1/2
• Effect of the Addition of Dexmedetomidine to Bupivacaine During Supraclavicular Brachial Plexus BlockadeCompletedNCT02049970Phase 4
• RCT of Efficacy and Safety of Sedation Compared to General Anesthesia for ERCPTerminatedNCT02046590Not applicable
• Effects of Dexmedetomidine During IRE Procedures for Solid TumoursCompletedNCT02044224Phase 4
• Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary InsomniaCompletedNCT02043977Phase 1
• Optimizing Propofol Dosing for (Preterm) Newborn Infants That Need Endotracheal IntubationTerminatedNCT02040909Phase 1
• Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual CycleCompletedNCT02035930Phase 4
• Comparison of Lormetazepam and Midazolam Used as Sedatives for Patients That Require Intensive CareCompletedNCT02022592Phase 4
• A Study Exmining the Effect of Multiple Doses of Bitopertin on the Single Dose Pharmacokinetics of Midazolam in Healthy Volunteers.WithdrawnNCT02019290Phase 1
• Effects of Dexmedetomidine During Radiofrequency Ablation of Abdominal TumoursCompletedNCT02016391Phase 4
• Effects of Etomidate on Postoperative Circadian Rhythm Changes of Salivary Cortisol in ChildrenStatus unknownNCT02013986Phase 4
• Efficacy of Peritonsillar Dexmedetomidine Infiltration for Postadenotonsillectomy PainCompletedNCT02013570Phase 4
• Nasal Fentanyl and Buccal Midazolam for Dying PatientsCompletedNCT02009306Phase 4
• A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized TrialCompletedNCT02009280Phase 4
• Small-dose Dexmedetomidine Effects on Recovery Profiles of Supratentorial Tumors Patients From General AnesthesiaStatus unknownNCT02007798Not applicable
• The Effect of Pnemoperitoneum on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Surgery According to Anesthesia Agents: Propofol Based Total Intravenous Anesthesia vs Desflurane AnesthesiaWithdrawnNCT02003768Not applicable
• Prothrombotic Factors and Anaesthesia in Prostate CancerCompletedNCT01998685Not applicable
• Sevoflurane and Propofol Anesthesia on Postoperative DeliriumStatus unknownNCT01995214Phase 4
• Phase 1 Study to Characterize the Safety and Pharmacokinetics of Single Intravenous Dose of Lorazepam in Healthy Japanese Adult SubjectsCompletedNCT01994668Phase 1
• The Effects of Midazolam on the Quality of Postoperative RecoveryCompletedNCT01993459Phase 4
• Oral Midazolam for Sedation in Esophagogastroduodenoscopy(EGD)Status unknownNCT01990937Phase 4
• Anti-histamines and Methacholine Challenges.CompletedNCT01985789Phase 4
• AnaConDa Long Term Sedation StudyCompletedNCT01983800Not applicable
• Effect of Intravenous Dexmedetomidine on Analgesic Duration of Infraclavicular BlockCompletedNCT01981369Not applicable
• Safety Study of Dexmedetomidine in Septic PatientsCompletedNCT01976754Not applicable
• Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane AnesthesiaCompletedNCT01975064Phase 4
• Propofol for Supreme LMA Insertion With and Without RemifentanilCompletedNCT01974648Phase 4
• Study of Use of Dexmedetomidine for Regional AnesthesiaWithdrawnNCT01969903Phase 2
• First-time-in-man, to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BP1.5375TerminatedNCT01965301Phase 1
• Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.CompletedNCT01964586Phase 4
• Effects of Different Types of Anesthesia on Stress Response in Laparoscopic Gastric Bypass for Type 2 Diabetes MellitusStatus unknownNCT01963546Not applicable
• Controlled Hypotension During Functional Endoscopic Sinus SurgeryCompletedNCT01956981Phase 4
• Anesthesia for Retinopathy of PrematurityCompletedNCT01955135Phase 4
• Alprazolam as Conscious Sedation for Upper Gastrointestinal EndoscopyCompletedNCT01949038Phase 2/3
• Xenon as an Adjuvant to Propofol Anaesthesia in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery.CompletedNCT01948765Phase 2
• The Effects of Dexmedetomidine on Early Stage Renal Functions in Pediatric PatientsCompletedNCT01948336Phase 4
• Remifentanil Use in Pediatric Rigid BronchoscopyCompletedNCT01947114Phase 4
• Propofol TCI Administered by Gastroenterologists During Endoscopy: a Randomized Double Blind Controlled StudyCompletedNCT01941888Phase 4
• Therapeutic Effect of Quetiapine on Methamphetamine-Induced PsychosisCompletedNCT01939093Phase 4

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