A Phase 4 interventional study of Dexmedetomidine and esmolol in Anesthesia; Adverse Effect, Reflex, Abnormal and Tinnitus, Spontaneous Oto-Acoustic Emission, sponsored by TC Erciyes University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2014-11-10.
Sponsored by TC Erciyes University · Phase 4, Interventional, and Treatment
The aim of this study is to find the Effects of Anesthetics Used in Hypotensive Anesthesia on Stapes Reflex and Distortion Product Auto Acoustic Emission.
This study was aimed at evaluating the effects of dexmedetomidine and esmolol on stapes reflex and distortion product auto acoustic emission. the stapes reflex and auto acoustic emission are of considerable diagnostic significances in otolaryngology this are objective methods for the assessment of auditory function.
21 studies on the registry are indexed under Reflex, Abnormal; 1 is open to participants now.
This study's enrollment of 47 is above the median of 25 across 15 interventional studies indexed under Reflex, Abnormal.
Browse Reflex, Abnormal studies →TC Erciyes University is the lead sponsor of 346 studies on the registry; 76 are open to participants now.
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Exclusion Criteria:
0,4-0,8 µg./kg./h dexmedetomidine
Drug: Dexmedetomidine
100- 300 µg./kg./min esmolol
Drug: esmolol
1 mcg/kg dexmedetomidine is applied bolus and 0.2 mcg/kg/h dexmedetomidine is applied iv infusion
Also known as: precedex
500 mcg/kg brevibloc is applied bolus and 100 mcg/kg/h iv infusion
Also known as: breviblock
distortion product auto acoustic emission
distortion product measurements will be performed in 1001, 1501, 2002, 3003, 4004, 6006, 7996 Hz frequencies and change from baseline in distortion product measurements at postoperative 1 day
Time frame: postoperative 1 day
stapes reflex
stapes muscle reflex measurements will be performed by electrical impedance. data will be taken as graphics. ıf there is an amplitude on graphic the data will be assumed as stapes reflex positive.Change from Baseline in stapes muscle reflex at postoperative 1 day
Time frame: postoperative 1 day
This study is completed, as verified in Nov 2014. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Dexmedetomidine · Esmolol